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CN105496608A - Aortic valve device conveyed by catheter - Google Patents

Aortic valve device conveyed by catheter
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Publication number
CN105496608A
CN105496608ACN201610029113.3ACN201610029113ACN105496608ACN 105496608 ACN105496608 ACN 105496608ACN 201610029113 ACN201610029113 ACN 201610029113ACN 105496608 ACN105496608 ACN 105496608A
Authority
CN
China
Prior art keywords
support frame
valve device
aortic valve
described support
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610029113.3A
Other languages
Chinese (zh)
Inventor
周庆亮
代高旭
孟坚
可大年
史欢欢
李阳
黄韬
杨宇霆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co Ltd
Beijing Med Zenith Medical Scientific Co Ltd
Original Assignee
BEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co LtdfiledCriticalBEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co Ltd
Priority to CN201610029113.3ApriorityCriticalpatent/CN105496608A/en
Publication of CN105496608ApublicationCriticalpatent/CN105496608A/en
Priority to PCT/CN2016/107221prioritypatent/WO2017121192A1/en
Pendinglegal-statusCriticalCurrent

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Abstract

The invention discloses an aortic valve device conveyed by a catheter. The aortic valve device comprises a supporting frame, wave leaflets and a skirt. The valve leaflets are fixed to the inner side of the middle of the supporting frame. The skirt is fixed along the periphery of the inner side of the supporting frame and fixed to the valve leaflets. An upper horn mouth structure in a three-valve form is formed by the upper end of the supporting frame. Three circular connection jaws used for loads of the supporting frame are arranged at the tail end of the horn mouth structure. Thorn-shaped positioning rods extending towards the bottom end of the supporting frame to be exposed are arranged on the outer side of the middle of the supporting frame. A lower horn mouth structure used for reducing outward expanding of perivalvular leakage is arranged at the bottom end of the supporting frame.

Description

A kind of through conduit conveying aortic valve valve device
Technical field
The present invention relates to medical instruments field, particularly relate to a kind of aortic valve valve device through conduit conveying.
Background technology
Along with increasing the weight of of aged tendency of population, the valve pathological changes caused after senile valvular heart disease and coronary heart disease, myocardial infarction is also more and more common.Surgical operation and the operative treatment such as Prosthetic valve replacement or valve forming are the radical cure methods of valvular heart disease, but for some advanced ages, multiple complication or the patient having surgery open chest surgery history, the mortality rate of surgery open chest surgery is very high.In recent years, along with the progress of interventional therapeutic technique, through this epoch-making technology of conduit artificial valve, push intervene operation to technology summit, and attempt all deficiencies solving surgery valve replacement.2002, the success that first case is performed the operation through conduit artificial valve replacement, indicated that this revolutionary interventional medicine technology has really entered into feasibility stage, through the development of 10 years, has had more than 10 ten thousand people by this reconstruction cardiac function, has obtained new life.
But existing aortic valve valve device or can recovery be discharged; Or accurate positioning but can not reclaim; Or recovery can be discharged and accurate positioning, but indication is limited.
Summary of the invention
The object of this invention is to provide a kind of aortic valve valve device through conduit conveying, it is for implantation into causing in the original position aortic valve of pathological changes because of aortic stenosis or incompetence, to solve the accurate positioning of aortic valve valve device and once release just irretrievable problem; Further, the problem adapting to various disease conditions is solved, as the aortic stenosis of severe calcification, independent aortic stenosis or incompetence and two lobe problems.
The invention provides a kind of aortic valve valve device through conduit conveying, described aortic valve valve device comprises: support frame; Be fixed on the lobe leaf inside described support frame mid portion; And fix and the shirt rim fixing with described lobe leaf along described support frame inner peripheral; Wherein, the upper end of described support frame forms the upper bell-mouth structure of air in three lobe forms; Bell-mouth structure of air end has that three of loading for described support frame are circular connects pawls on described; The thorn-like locating rod exposed that outside the described mid portion of described support frame, the direction, bottom of oriented described support frame extends; There is the lower bell-mouth structure of air expanded outwardly for reducing perivalvular leakage the bottom of described support frame.
Selectively, the material of described support frame is memorial alloy, such as, be nickel-titanium alloy material; Described mid portion is vertical section, and the extent of opening of described lower bell-mouth structure of air is less than the extent of opening of described upper bell-mouth structure of air.
Selectively, described support frame is the network that the grid cell assumed diamond in shape is formed; And the inclination angle that the end of described upper bell-mouth structure of air and lower bell-mouth structure of air departs from the central axis of described support frame is respectively 1 ° to 15 °.
Selectively, described circle connects the center of pawl be circular or square through hole or without hole shape, described circular connection pawl is connected by short connecting rod with upper bell-mouth structure of air.
Selectively, described thorn-like locating rod root position to described support frame bottom distance be 10mm to 25mm.
Selectively, described thorn-like locating rod distributes along described support frame even circumferential, and quantity is 3 to 12.
Selectively, the length of described thorn-like locating rod is 4mm to 15mm; The width of thorn-like locating rod is 0.3mm to 1mm.
Selectively, the circle diameter of the circumscribed circle of described thorn-like locating rod is greater than described support frame mid portion vertical section diameter 3mm to 9mm.
Selectively, described thorn-like locating rod and support frame can be integral structure or split structure, and integral structure adopts cut to form, and split structure adopts laser weld to form.
Selectively, the lower bell-mouth structure of air height of the expansion of described support frame bottom is 3mm to 8mm, and its diameter is greater than described support frame mid portion vertical section 3mm to 6mm.
Selectively, the mid portion of described support frame and the upper bell-mouth structure of air of described support frame are connected to each other by short connecting rod.
Selectively, described short connecting rod length is 1.5mm to 4mm, and width is 0.25mm to 1mm.
Selectively, the short connecting rod of left and right indent is adopted to connect between the adjacent described grid cell of described support frame.
Selectively, the minimum widith of the short connecting rod of described left and right indent is 0.25mm to 0.5mm.
Selectively, the short connecting rod of described left and right indent is the concave inward structure that the concave inward structure that formed of two semicircles in left and right or a bit of straightway add left and right circular arc and formed.
Selectively, the material of described lobe leaf is Cor Sus domestica bag, bovine pericardium, Cor Equi bag or macromolecular material politef.
Selectively, the material of described shirt rim is Cor Sus domestica bag, bovine pericardium, Cor Equi bag, macromolecular material politef or woven dacron.
The advantage of the present invention end comprised by being arranged to bell-mouth structure of air and bell-mouth structure of air in the support frame upper end of aortic valve valve has three circularly to connect pawls, achieves loading and the recovery of aortic valve valve device; The thorn-like locating rod exposed downwards by the mid portion of support frame, is achieved the accurate location of aortic valve valve device, makes operation process more safe and reliable.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of a kind of aortic valve valve device of the present invention;
Fig. 2 is the top view of a kind of aortic valve valve device of the present invention;
Fig. 3 is the expansion schematic diagram of a kind of aortic valve valve device of the present invention;
Fig. 4 is the expansion schematic diagram of a kind of aortic valve valve device thorn-like locating rod of the present invention;
Fig. 5 is the schematic diagram that aortic valve valve device of the present invention is loaded into induction system;
Fig. 6 is the schematic diagram of aortic valve valve device thorn-like locating rod of the present invention release;
Fig. 7 is the schematic diagram of aortic valve valve device thorn-like locating rod of the present invention and the release of support frame bottom;
Fig. 8 is that aortic valve valve device of the present invention discharges schematic diagram completely;
Fig. 9 is that aortic valve valve device of the present invention is at cardiac position thorn-like locating rod location schematic diagram;
Figure 10 is that aortic valve valve device of the present invention is at cardiac position thorn-like locating rod and location, support bottom schematic diagram;
Figure 11 is that aortic valve valve device of the present invention discharges schematic diagram completely at cardiac position;
Detailed description of the invention
A kind of aortic valve valve device through conduit conveying of the present invention for implantation into causing in the original position aortic valve of pathological changes because of aortic stenosis or incompetence, to solve the accurate positioning of aortic valve valve device and once release just irretrievable problem; Also attempt in addition to solve the problem adapting to various disease conditions, as the aortic stenosis of severe calcification, independent aortic stenosis or incompetence and two lobe problems.
Below in conjunction with accompanying drawing, embodiments of the invention are described in detail.
A kind of aortic valve valve device 100 as shown in Fig. 1 to Fig. 4, for implantation into causing in the original position aortic valve of pathological changes because of aortic stenosis or incompetence, comprise: support frame, be fixed on the lobe leaf 104 inside described support frame mid portion, and fix and the shirt rim 102 fixing with described lobe leaf along described support frame inner peripheral.Furtherly, shirt rim 102 forms a circle along support frame surrounding, and fixes by suture; Lobe leaf 104 is three (please refer to Fig. 2), is sewn in support frame mid portion, and sews up with shirt rim 102 is fixing.
Described support frame comprises: formed in the upper end of described support frame in the upper bell-mouth structure of air 105 of three lobe forms, bell-mouth structure of air end has that three of loading for described support frame are circular connects pawls 106 on described; The mid portion of described support frame, the thorn-like locating rod 103 exposed that outside it, direction, bottom of oriented described support frame extends; Be positioned at the lower bell-mouth structure of air 101 expanded outwardly for reducing perivalvular leakage of the bottom of described support frame.(please refer to Fig. 1).
The material of described support frame can be memorial alloy, such as, be nickel-titanium alloy material.
Described mid portion is vertical section, and the extent of opening of described lower bell-mouth structure of air 101 is less than the extent of opening of described upper bell-mouth structure of air 105.
Described support frame is the network that the grid cell assumed diamond in shape is formed; The short connecting rod of left and right indent is adopted to connect between the adjacent described grid cell of described support frame.Selectively, the minimum widith of the short connecting rod of described left and right indent is 0.25mm to 0.5mm.Selectively, the short connecting rod of described left and right indent is the concave inward structure that the concave inward structure that formed of two semicircles in left and right or a bit of straightway add left and right circular arc and formed.
The inclination angle that the end of described upper bell-mouth structure of air and lower bell-mouth structure of air departs from the central axis of described support frame is respectively 1 ° to 15 °.Lower bell-mouth structure of air 101 seamlessly transits with the mid portion of support frame; Mid portion and the upper bell-mouth structure of air 105 of support frame seamlessly transit; The mid portion of support frame is connected (please refer to Fig. 4) by short connecting rod 107 with upper bell-mouth structure of air 105, and described short connecting rod length is 1.5mm to 4mm, and width is 0.25mm to 1mm.Short connecting rod 108 is adopted to connect (please refer to Fig. 4) between the grid cell assumed diamond in shape of support frame; Upper bell-mouth structure of air 105 mid portion assumes diamond in shape expansion, and upper bell-mouth structure of air 105 is uniformly distributed in support frame surrounding; The circular pawl 106 that connects is connected by short connecting rod with upper bell-mouth structure of air 105, and circular to connect pawl 106 be hollow or solid construction, and furtherly, the center of described circular connection pawl 106 is circle or square through hole or without hole shape.
Thorn-like locating rod 103 is positioned at support frame mid portion, is circularly and evenly distributed in support frame mid portion, and the lower bell-mouth structure of air 101 of support frame is pointed in the direction of thorn; The root position of described thorn-like locating rod is 10mm to 25mm to the bottom distance of described support frame.Described thorn-like locating rod distributes along described support frame even circumferential, and quantity is 3 to 12.Selectively, the length of described thorn-like locating rod is 4mm to 15mm; The width of thorn-like locating rod is 0.3mm to 1mm.The circle diameter of the circumscribed circle of described thorn-like locating rod is greater than described support frame mid portion vertical section diameter 3mm to 9mm.Described thorn-like locating rod and support frame can be integral structure or split structure, and integral structure adopts cut to form, and split structure adopts laser weld to form.
Lower bell-mouth structure of air height is 3mm to 8mm, and its external diameter of a circle is greater than described support frame mid portion vertical section 3mm to 6mm.
The material of described lobe leaf and the material of described shirt rim can be respectively Cor Sus domestica bag, bovine pericardium, Cor Equi bag or macromolecular material politef.
There are three circularly to connect pawls by the end being arranged to bell-mouth structure of air and bell-mouth structure of air in the support frame upper end of aortic valve valve, achieve loading and the recovery of aortic valve valve device; The thorn-like locating rod exposed downwards by the mid portion of support frame, is achieved the accurate location of aortic valve valve device, makes operation process more safe and reliable.
One described in the embodiment of the present invention is as follows through conduit conveying aortic valve valve device work process:
First described aortic valve valve device 100 is shunk by certain device in the head end 201 and loading sheath 202 being loaded into induction system 200 (please refer to Fig. 5), moved backward by the loading sheath 202 of handle 203 by induction system 200, the thorn-like locating rod 103 of described aortic valve valve device 100 is discharged (please refer to Fig. 6 and Fig. 9), now due to the characteristic of the memorial alloy of described aortic valve valve device 100 material self, thorn-like locating rod 103 automatic expansion, slowly push induction system 200 downwards, thorn-like locating rod 103 is made to touch human body natural's lobe leaf texture 300, stop pushing induction system 200.Moved forward by the head end 201 of handle 203 by induction system 200 again, the lower bell-mouth structure of air 101 of described aortic valve valve device 100 is discharged from the head end 201 of induction system 200, due to the characteristic of the memorial alloy of described aortic valve valve device 100 material self, lower bell-mouth structure of air 101 automatic expansion (please refer to Fig. 7), human body natural's lobe leaf texture 300 is strutted, now human body natural's lobe leaf texture 300 is between the lower bell-mouth structure of air 101 of described aortic valve valve device 100 and thorn-like locating rod 103 (please refer to Figure 10), described aortic valve valve device 100 completes accurate location.Again by the handle 203 of induction system 200, loading sheath 202 is continued to move backward, the upper bell-mouth structure of air 105 of described aortic valve valve device 100 is connected pawl 106 to discharge (please refer to Fig. 8) from loading sheath 202 with circle, due to the characteristic of the memorial alloy of self of described aortic valve valve device 100 material, upper bell-mouth structure of air 105 automatic expansion is to maximum, fixing (please refer to Figure 11) is fitted with blood vessel wall, last induction system 200 is connected pawl 106 with circle and departs from, withdraw from induction system 200, described aortic valve valve device 100 has been implanted.
Above embodiment is only for illustration of the present invention; and be not limitation of the present invention; the those of ordinary skill of relevant technical field; without departing from the spirit and scope of the present invention; can also make a variety of changes and modification; therefore all equivalent technical schemes also belong to category of the present invention, and scope of patent protection of the present invention should be defined by the claims.

Claims (10)

1., through an aortic valve valve device for conduit conveying, described aortic valve valve device comprises: support frame; Be fixed on the lobe leaf inside described support frame mid portion; And fix and the shirt rim fixing with described lobe leaf along described support frame inner peripheral; It is characterized in that: the upper end of described support frame forms the upper bell-mouth structure of air in three lobe forms; Bell-mouth structure of air end has that three of loading for described support frame are circular connects pawls on described; The thorn-like locating rod exposed that outside the described mid portion of described support frame, the direction, bottom of oriented described support frame extends; There is the lower bell-mouth structure of air expanded outwardly for reducing perivalvular leakage the bottom of described support frame.
CN201610029113.3A2016-01-112016-01-11Aortic valve device conveyed by catheterPendingCN105496608A (en)

Priority Applications (2)

Application NumberPriority DateFiling DateTitle
CN201610029113.3ACN105496608A (en)2016-01-112016-01-11Aortic valve device conveyed by catheter
PCT/CN2016/107221WO2017121192A1 (en)2016-01-112016-11-25Apparatus, having spinous positioning rods, for transcatheter delivery of aortic valve

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
CN201610029113.3ACN105496608A (en)2016-01-112016-01-11Aortic valve device conveyed by catheter

Publications (1)

Publication NumberPublication Date
CN105496608Atrue CN105496608A (en)2016-04-20

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ID=55705178

Family Applications (1)

Application NumberTitlePriority DateFiling Date
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CN (1)CN105496608A (en)
WO (1)WO2017121192A1 (en)

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CN106890035A (en)*2017-04-172017-06-27乐普(北京)医疗器械股份有限公司 A transcatheter implantable aortic valve device
WO2017121192A1 (en)*2016-01-112017-07-20北京迈迪顶峰医疗科技有限公司Apparatus, having spinous positioning rods, for transcatheter delivery of aortic valve
CN107088112A (en)*2017-05-182017-08-25金仕生物科技(常熟)有限公司One kind is through conduit aortic valve
WO2018099484A1 (en)*2016-12-022018-06-07Sino Medical Sciences Technology Inc.Low profile heart valve and delivery system
CN109124829A (en)*2018-06-292019-01-04金仕生物科技(常熟)有限公司It is a kind of through conduit aortic valve and preparation method thereof
CN109549755A (en)*2017-09-252019-04-02先健科技(深圳)有限公司Heart valve
WO2019062366A1 (en)*2017-09-292019-04-04上海微创心通医疗科技有限公司Heart valve prosthesis
CN109925095A (en)*2017-12-182019-06-25先健科技(深圳)有限公司Heart valve
CN109984868A (en)*2017-12-302019-07-09上海微创心通医疗科技有限公司Heart valve prosthesis and conveyer
WO2022042310A1 (en)*2020-08-252022-03-03北京市普惠生物医学工程有限公司Artificial valve and valve delivery system
CN114903653A (en)*2022-04-152022-08-16潘湘斌 Aortic valve stent and system for delivering aortic valve stent
CN115414157A (en)*2022-11-072022-12-02广东捍宇医疗科技有限公司Valve device and valve device system
CN116570404A (en)*2023-07-132023-08-11上海威高医疗技术发展有限公司Valve support and artificial heart valve prosthesis
CN116616956A (en)*2023-04-262023-08-22福建省立医院Artificial implantation heart valve
CN116616962A (en)*2023-07-242023-08-22乐普(北京)医疗器械股份有限公司Suture-free artificial heart valve
WO2023197328A1 (en)*2022-04-152023-10-19潘湘斌Aortic valve stent and system for conveying aortic valve stent
WO2025148560A1 (en)*2024-01-112025-07-17北京迈迪顶峰医疗科技股份有限公司Valve stent, method for processing valve stent, and artificial valve

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Cited By (21)

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Publication numberPriority datePublication dateAssigneeTitle
WO2017121192A1 (en)*2016-01-112017-07-20北京迈迪顶峰医疗科技有限公司Apparatus, having spinous positioning rods, for transcatheter delivery of aortic valve
WO2018099484A1 (en)*2016-12-022018-06-07Sino Medical Sciences Technology Inc.Low profile heart valve and delivery system
CN106890035A (en)*2017-04-172017-06-27乐普(北京)医疗器械股份有限公司 A transcatheter implantable aortic valve device
WO2018192197A1 (en)*2017-04-172018-10-25乐普(北京)医疗器械股份有限公司Aortic valve device
CN107088112A (en)*2017-05-182017-08-25金仕生物科技(常熟)有限公司One kind is through conduit aortic valve
CN109549755A (en)*2017-09-252019-04-02先健科技(深圳)有限公司Heart valve
WO2019062366A1 (en)*2017-09-292019-04-04上海微创心通医疗科技有限公司Heart valve prosthesis
CN109925095A (en)*2017-12-182019-06-25先健科技(深圳)有限公司Heart valve
CN109984868A (en)*2017-12-302019-07-09上海微创心通医疗科技有限公司Heart valve prosthesis and conveyer
CN109124829A (en)*2018-06-292019-01-04金仕生物科技(常熟)有限公司It is a kind of through conduit aortic valve and preparation method thereof
WO2022042310A1 (en)*2020-08-252022-03-03北京市普惠生物医学工程有限公司Artificial valve and valve delivery system
CN114903653A (en)*2022-04-152022-08-16潘湘斌 Aortic valve stent and system for delivering aortic valve stent
WO2023197328A1 (en)*2022-04-152023-10-19潘湘斌Aortic valve stent and system for conveying aortic valve stent
CN114903653B (en)*2022-04-152025-07-01潘湘斌 Aortic valve stent and system for delivering aortic valve stent
CN115414157A (en)*2022-11-072022-12-02广东捍宇医疗科技有限公司Valve device and valve device system
CN116616956A (en)*2023-04-262023-08-22福建省立医院Artificial implantation heart valve
CN116570404A (en)*2023-07-132023-08-11上海威高医疗技术发展有限公司Valve support and artificial heart valve prosthesis
CN116570404B (en)*2023-07-132023-11-03上海威高医疗技术发展有限公司Valve support and artificial heart valve prosthesis
CN116616962A (en)*2023-07-242023-08-22乐普(北京)医疗器械股份有限公司Suture-free artificial heart valve
CN116616962B (en)*2023-07-242023-12-19乐普(北京)医疗器械股份有限公司 Suture-free artificial heart valve
WO2025148560A1 (en)*2024-01-112025-07-17北京迈迪顶峰医疗科技股份有限公司Valve stent, method for processing valve stent, and artificial valve

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