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CN105496607A - Aortic valve device conveyed by catheter - Google Patents

Aortic valve device conveyed by catheter
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Publication number
CN105496607A
CN105496607ACN201610029112.9ACN201610029112ACN105496607ACN 105496607 ACN105496607 ACN 105496607ACN 201610029112 ACN201610029112 ACN 201610029112ACN 105496607 ACN105496607 ACN 105496607A
Authority
CN
China
Prior art keywords
main support
valve device
aortic valve
mouth structure
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610029112.9A
Other languages
Chinese (zh)
Inventor
代高旭
周庆亮
孟坚
可大年
史欢欢
李阳
黄韬
杨宇霆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co Ltd
Beijing Med Zenith Medical Scientific Co Ltd
Original Assignee
BEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co LtdfiledCriticalBEIJING MAIDI DINGFENG MEDICAL TECHNOLOGY Co Ltd
Priority to CN201610029112.9ApriorityCriticalpatent/CN105496607A/en
Publication of CN105496607ApublicationCriticalpatent/CN105496607A/en
Priority to PCT/CN2016/107224prioritypatent/WO2017121194A1/en
Pendinglegal-statusCriticalCurrent

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Abstract

The invention provides an aortic valve device conveyed by a catheter. The aortic valve device comprises a main support, wave leaflets and a skirt. The valve leaflets are fixed to the inner side of the middle of the main support. The skirt is fixed along the periphery of the inner side of the main support and fixed to the valve leaflets. An upper horn mouth structure in a three-valve form is formed by the upper end of the main support. Three circular connection jaws used for loads of the main support are arranged at the tail end of the horn mouth structure. A lower horn mouth structure used for reducing outward expanding of perivalvular leakage is arranged at the bottom end of the main support. Three lower end circular connection jaws are arranged at the lower end of the lower horn mouth structure. The aortic valve device further comprises a positioning ring located on the lower side of the main support and used for conducting positioning. The positioning ring comprises three V-shaped or U-shaped arc sections. The ends of the V-shaped or U-shaped arc sections are connected to form an annular shape. Three positioning circular connection jaws are formed at the ends. The lower end circular connection jaws are connected with the corresponding positioning circular connection jaws through flexible positioning lines respectively.

Description

A kind of through conduit conveying aortic valve valve device
Technical field
The present invention relates to medical instruments field, particularly relate to a kind of aortic valve valve device through conduit conveying.
Background technology
Along with increasing the weight of of aged tendency of population, the valve pathological changes caused after senile valvular heart disease and coronary heart disease, myocardial infarction is also more and more common.Surgical operation and the operative treatment such as Prosthetic valve replacement or valve forming are the radical cure methods of valvular heart disease, but for some advanced ages, multiple complication or the patient having surgery open chest surgery history, the mortality rate of surgery open chest surgery is very high.In recent years, along with the progress of interventional therapeutic technique, through this epoch-making technology of conduit artificial valve, push intervene operation to technology summit, and attempt all deficiencies solving surgery valve replacement.2002, the success that first case is performed the operation through conduit artificial valve replacement, indicated that this revolutionary interventional medicine technology has really entered into feasibility stage, through the development of 10 years, has had more than 10 ten thousand people by this reconstruction cardiac function, has obtained new life.
But existing aortic valve valve device or can recovery be discharged; Or accurate positioning but can not reclaim; Or recovery can be discharged and accurate positioning, but indication is limited.
Summary of the invention
The object of this invention is to provide a kind of aortic valve valve device through conduit conveying, this aortic valve valve device is for implantation into because of aortic stenosis or incompetence or backflow and cause in the original position aortic valve of pathological changes, to solve the problem of aortic valve valve device accurate positioning; Further, solve and adapt to the problem of various disease conditions, as aortic stenosis or incompetence or backflow or the disease such as two lobes.
The invention provides a kind of aortic valve valve device through conduit conveying, described aortic valve valve device comprises: main support; Be fixed on the lobe leaf inside described main support mid portion; And fix and the shirt rim fixing with described lobe leaf along described main support inner peripheral; Wherein, the upper end of described main support forms the upper bell-mouth structure of air in three lobe forms; Bell-mouth structure of air upper end has three upper ends circles of the loading for described main support to connect pawls on described; There is the lower bell-mouth structure of air expanded outwardly for reducing perivalvular leakage the bottom of described main support; The lower end of described lower bell-mouth structure of air has three lower end circles to connect pawl; Described aortic valve valve device also comprises the locating ring for locating be positioned on the downside of described main support, described locating ring comprises three V-shaped or U-shaped arc section, the end of V-shaped described in each or U-shaped arc section is connected with each other formation ring-type, and on described end, forms three positioning rounds connect pawls; Described lower end circle connects pawl and is connected pawl with corresponding positioning round and connects respectively by the position line of flexibility.
Selectively, described main support and/or described locating ring are nickel-titanium alloy material; Described mid portion is vertical section, and the extent of opening of described lower bell-mouth structure of air is less than the extent of opening of described upper bell-mouth structure of air.Furtherly, lower bell-mouth structure of air is the straight bell-mouth structure of air of outside micro-expansion.Lower bell-mouth structure of air height is 3mm to 8mm.
Selectively, described main support is the network that the grid cell assumed diamond in shape is formed; And the inclination angle that the end of described upper bell-mouth structure of air and lower bell-mouth structure of air departs from the central axis of described main support is respectively 1 ° to 15 °.
Selectively, described upper end circle connects the center of pawl be circular or square through hole or without hole shape, described upper end circular connection pawl is connected by short connecting rod with upper bell-mouth structure of air.
Selectively, the mid portion of described main support and the upper bell-mouth structure of air of described main support are connected to each other by short connecting rod.Preferably, described short connecting rod length is 1.5mm to 4mm, and width is 0.25mm to 1mm.
Selectively, the short connecting rod of left and right indent is adopted to connect between the adjacent described grid cell of described main support.The minimum widith of the short connecting rod of described left and right indent is 0.25mm to 0.5mm.
Selectively, the short connecting rod of described left and right indent is the concave inward structure that the concave inward structure that formed of two circular arcs in left and right or a bit of straightway add left and right circular arc and formed.
Selectively, the centre that described lower end circle connects pawl is circular hole or square hole, and the bottom that described lower end circle connects pawl is the arc structure of indent; Lower end circle connects pawl and is uniformly distributed in main support bottom.
The centre that described positioning round connects pawl is circular hole or square hole, and the top that described positioning round connects pawl is the arc structure of indent.
Preferably, described lower end circle connects the circular arc size of pawl bottom indent is that radius 0.3mm is to radius 1mm.The circular arc size that described positioning round connects pawl top indent is that radius 0.3mm is to radius 1mm.
Selectively, the material of described lobe leaf is Cor Sus domestica bag, bovine pericardium, Cor Equi bag or macromolecular material politef; The material of described shirt rim is Cor Sus domestica bag, bovine pericardium, Cor Equi bag, macromolecular material politef or woven dacron.
Selectively, described position line is the wire-shaped material such as the macromolecular material silk thread such as common suture or degradable medical stitching thread or titanium-nickel wire.
Selectively, described locating ring is made up of 3 to 12 V-shaped or U-shaped construction unit, and bar is wide is 0.3mm to 1mm, and described locating ring height is 7mm to 15mm.
Preferably, the length of described position line increases 5mm to 12mm than the height of described locating ring.
Advantage of the present invention is three circular connection pawls by being arranged to bell mouth shape structure end in the main support upper end of aortic valve valve, achieves loading and the recovery of aortic valve valve device; By the straight horn mouth shape of main support bottom, decrease perivalvular leakage; By position line and the locating ring of main support lower end, achieve the accurate location of aortic valve valve device, thus make operation process more safe and reliable.
Accompanying drawing explanation
Fig. 1 is the deployed condition schematic diagram of a kind of aortic valve valve device of the present invention;
Fig. 2 is the location schematic diagram of a kind of aortic valve valve device of the present invention;
Fig. 3 is a kind of aortic valve valve device locating ring structure schematic diagram of the present invention;
Fig. 4 is the schematic diagram that aortic valve valve device of the present invention is loaded into induction system;
Fig. 5 is the schematic diagram of aortic valve valve device locating ring of the present invention half release;
Fig. 6 is the schematic diagram that aortic valve valve device locating ring of the present invention discharges completely;
Fig. 7 is that aortic valve valve device of the present invention is transported to cardiac position schematic diagram;
Fig. 8 is that aortic valve valve device of the present invention partly discharges schematic diagram at cardiac position locating ring;
Fig. 9 is that aortic valve valve device of the present invention discharges schematic diagram completely at cardiac position locating ring;
Figure 10 is that aortic valve valve device of the present invention is at cardiac position main support location schematic diagram;
Figure 11 is that aortic valve valve device of the present invention discharges schematic diagram completely at cardiac position;
Detailed description of the invention
The invention provides a kind of aortic valve valve device through conduit conveying, this aortic valve valve device is for implantation into because of aortic stenosis or incompetence or backflow and cause in the original position aortic valve of pathological changes, to solve the problem of aortic valve valve device accurate positioning; Further, solve and adapt to the problem of various disease conditions, as aortic stenosis or incompetence or backflow or the disease such as two lobes.
Below in conjunction with accompanying drawing, the embodiment of the present invention is described in further detail.
A kind of aortic valve valve device 100 as shown in Fig. 1 to Fig. 3, for implantation into because of aortic stenosis or backflow and cause in the original position aortic valve of pathological changes, described aortic valve valve device comprises: main support; Be fixed on the lobe leaf 104 inside described main support mid portion; And fix and the shirt rim 102 fixing with described lobe leaf 104 along described main support inner peripheral; Furtherly, shirt rim 102 forms a circle along main support surrounding, and fixes by suture; Lobe leaf 104 is three, is sewn in main support mid portion, and sews up with shirt rim 102 is fixing.
See Fig. 1, the upper end of described main support forms the upper bell-mouth structure of air 105 in three lobe forms; Bell-mouth structure of air 105 upper end has three upper ends circles of the loading for described main support to connect pawls 106 on described, and it can be hollow or solid; There is the lower bell-mouth structure of air 101 expanded outwardly for reducing perivalvular leakage the bottom of described main support; The lower end of described lower bell-mouth structure of air 101 has three lower end circles to connect pawl 110; Described aortic valve valve device also comprises the locating ring 103 for locating be positioned on the downside of described main support, described locating ring 103 comprises three V-shaped or U-shaped arc section, the end of V-shaped described in each or U-shaped arc section is connected with each other formation ring-type, and on described end, forms three positioning rounds connect pawls 111; Described lower end circle connects pawl 110 and is connected pawl 111 with corresponding positioning round and connects respectively by the position line 107 of flexibility.
Described main support and described locating ring 103 can be nickel-titanium alloy material; Described mid portion is vertical section, and the extent of opening of described lower bell-mouth structure of air 101 is less than the extent of opening of described upper bell-mouth structure of air 105.Furtherly, lower bell-mouth structure of air 101 is the straight bell-mouth structure of air of outside micro-expansion.Lower bell-mouth structure of air 101 is highly 3mm to 8mm.
The network that described main support can be formed for the grid cell assumed diamond in shape; And the inclination angle that the end of described upper bell-mouth structure of air 105 and lower bell-mouth structure of air 101 departs from the central axis of described main support is respectively 1 ° to 15 °.Main support mid portion and lower bell-mouth structure of air 101 and upper bell-mouth structure of air 105 seamlessly transit.
The center that described upper end circle connects pawl 106 be circular or square through hole or without hole shape, described upper end circular connection pawl 106 is connected by short connecting rod with upper bell-mouth structure of air 105.
See Fig. 2, the mid portion of described main support and the upper bell-mouth structure of air 105 of described main support are connected to each other by short connecting rod 108.Preferably, described short connecting rod length is 1.5mm to 4mm, and width is 0.25mm to 1mm.
The short connecting rod of left and right indent can be adopted between the adjacent described grid cell of described main support to connect 109.The minimum widith of the short connecting rod of described left and right indent is 0.25mm to 0.5mm.
The concave inward structure that the short connecting rod of described left and right indent can be formed for two, left and right circular arc or a bit of straightway add the concave inward structure that left and right circular arc is formed.
The centre that described lower end circle connects pawl 110 can be circular hole or square hole, and the bottom that described lower end circle connects pawl 110 is the arc structure of indent; Lower end circle connects pawl 110 and is uniformly distributed in main support bottom.
The centre that described positioning round connects pawl 111 is circular hole or square hole, and there is the arc structure 112 (see Fig. 3) of indent on the top of described positioning round connection pawl 111.
The circular arc size that described lower end circle connects pawl 110 bottom indent is that radius 0.3mm is to radius 1mm.The circular arc size that described positioning round connects pawl 111 top indent is that radius 0.3mm is to radius 1mm.
The material of described lobe leaf can be Cor Sus domestica bag, bovine pericardium, Cor Equi bag or macromolecular material politef; The material of described shirt rim is Cor Sus domestica bag, bovine pericardium, Cor Equi bag, macromolecular material politef or woven dacron.
Described position line 107 can be the wire-shaped material such as the macromolecular material silk thread such as common suture or degradable medical stitching thread or titanium-nickel wire.
In addition, described locating ring 103 also can be made up of 3 to 12 V-shaped or U-shaped construction unit, and bar is wide is 0.3mm to 1mm, and described locating ring 103 is highly 7mm to 15mm.
The length of described position line 107 can increase 5mm to 12mm than the height of described locating ring 103.
In addition, the shape that can assume diamond in shape in the middle part of upper bell-mouth structure of air 105 launches, and upper bell-mouth structure of air 105 is uniformly distributed in main support surrounding.
One described in the embodiment of the present invention is as follows through conduit conveying aortic valve valve device work process:
First described aortic valve valve device 100 (comprising main support and locating ring 103) entered in the loading sheath 202 of induction system 200 (to please refer to Fig. 4) by certain device compression loaded, induction system 200 comprises head end 201, loads sheath 202 and handle 203 etc.By intervening mode, induction system 200 is transported to human lesion position (please refer to Fig. 7).Then by handle 203, the loading sheath 202 of induction system 200 is moved backward to fixed position, the locating ring 103 half of described aortic valve valve device 100 is discharged (please refer to Fig. 5 and Fig. 8), now due to described aortic valve valve device 100 material shape memory characteristic, locating ring 103 automatic expansion, form horn mouth shape (please refer to Fig. 5 and Fig. 8), slowly push induction system 200 to ventricle direction again, make locating ring 103 touch the bottom of human body natural's lobe leaf texture 300, stop pushing induction system 200.By handle 203, the loading sheath 202 of induction system 200 is moved backward to fixed position again again, locating ring 103 is discharged completely from loading sheath 202, now locating ring 103 is due to material shape memory characteristic, and complete automatic expansion is to full-size (please refer to Fig. 6 and 9).Continue to push induction system 200 to ventricle direction, make to load sheath 202 and cross human body natural's lobe leaf texture 300, until position line 107 is in tensioned state, induction system 200 is also in spacing state (please refer to Figure 10) simultaneously, and then load sheath 202 by handle 203 is slowly mobile backward, the lower bell-mouth structure of air 101 of main support is slowly discharged from the loading sheath 202 of induction system 200, due to described aortic valve valve device 100 material shape memory characteristic, lower bell-mouth structure of air 101 automatic expansion is to maximum, human body natural's lobe leaf texture 300 is strutted, now human body natural's lobe leaf texture 300 is between the lower bell-mouth structure of air 101 of described aortic valve valve device 100 and locating ring 103 (please refer to Figure 11), described aortic valve valve device 100 completes accurate location.Again by the handle 203 of induction system 200, loading sheath 202 is continued to move backward, the upper bell-mouth structure of air 105 of described aortic valve valve device 100 is connected pawl 106 with upper end circle discharge from loading sheath 202, due to the shape memory characteristic of described aortic valve valve device 100 material, upper bell-mouth structure of air 105 automatic expansion is to maximum, fixing (please refer to Figure 11) is fitted with blood vessel wall, induction system 200 is connected pawl 106 with upper end circle, finally withdraw from induction system 200, described aortic valve valve device 100 has been implanted.
Above embodiment is only for illustration of the present invention; and be not limitation of the present invention; the those of ordinary skill of relevant technical field; without departing from the spirit and scope of the present invention; can also make a variety of changes and modification; therefore all equivalent technical schemes also belong to category of the present invention, and scope of patent protection of the present invention should be defined by the claims.

Claims (10)

1., through an aortic valve valve device for conduit conveying, described aortic valve valve device comprises: main support; Be fixed on the lobe leaf inside described main support mid portion; And fix and the shirt rim fixing with described lobe leaf along described main support inner peripheral; It is characterized in that: the upper end of described main support forms the upper bell-mouth structure of air in three lobe forms; Bell-mouth structure of air upper end has three upper ends circles of the loading for described main support to connect pawls on described; There is the lower bell-mouth structure of air expanded outwardly for reducing perivalvular leakage the bottom of described main support; The lower end of described lower bell-mouth structure of air has three lower end circles to connect pawl; Described aortic valve valve device also comprises the locating ring for locating be positioned on the downside of described main support, described locating ring comprises three V-shaped or U-shaped arc section, the end of V-shaped described in each or U-shaped arc section is connected with each other formation ring-type, and on described end, forms three positioning rounds connect pawls; Described lower end circle connects pawl and is connected pawl with corresponding positioning round and connects respectively by the position line of flexibility.
CN201610029112.9A2016-01-112016-01-11Aortic valve device conveyed by catheterPendingCN105496607A (en)

Priority Applications (2)

Application NumberPriority DateFiling DateTitle
CN201610029112.9ACN105496607A (en)2016-01-112016-01-11Aortic valve device conveyed by catheter
PCT/CN2016/107224WO2017121194A1 (en)2016-01-112016-11-25Transcatheter aortic valve device having positioning ring

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
CN201610029112.9ACN105496607A (en)2016-01-112016-01-11Aortic valve device conveyed by catheter

Publications (1)

Publication NumberPublication Date
CN105496607Atrue CN105496607A (en)2016-04-20

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WO2017121194A1 (en)*2016-01-112017-07-20北京迈迪顶峰医疗科技有限公司Transcatheter aortic valve device having positioning ring
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