技术领域technical field
本发明属于生物医学电子学医疗仪器技术领域。涉及一种注射式神经刺激器，更具体是涉及一种射频能量供电的注射式神经刺激器。本发明主要应用于生物医疗中，对神经或肌肉进行刺激。The invention belongs to the technical field of biomedical electronics medical instruments. It relates to an injectable nerve stimulator, and more particularly relates to an injectable nerve stimulator powered by radio frequency energy. The invention is mainly used in biomedicine to stimulate nerves or muscles.
背景技术Background technique
神经刺激器是一种生物医疗电子装置。它用于产生低频电脉冲对生物体进行功能性神经电刺激，以达到减轻病痛症状，恢复或调整神经或肌肉的功能等作用。神经刺激器可以由神经科医师，护士或经过培训的技术人员来进行校准，以满足个别病人的具体需要。目前市场上比较成熟和应用最广的是植入式神经刺激器。这种神经刺激器必须通过外科手术将其植入到人或其他动物的身体内，具有以下局限性：1)将植入式神经刺激器植入到身体内需要通过较长时间的手术(如植入脑深部刺激器需要约十二个小时)，病人必须忍受一定的痛苦；2)相对于特定的需要刺激的靶点神经，植入式神经刺激器的尺寸相对较大，不能被植入到形状或体积受限的靶点神经或肌肉组织中(如脑部)；为了将刺激信号传导至脑部部位，需要在电极上引入较长的电极延长导线；但是电极延长导线很容易发生移动，有可能在错误的位置引发一个电刺激，这会极大地增加感染的风险。而且在植入式神经刺激器的任何部分所诱发的感染往往会扩散到整个系统中，在这种情况下，必须再次通过外科手术对电池或整个植入神经刺激器进行更换；3)当前市场上通用的植入式神经刺激器主要使用非充电电池供电，电能在4到10年内会被耗尽，此时需要再次手术更换电池，因此其全寿命周期较短；4)植入植入式神经刺激器在植入体内后，如果发生不适，在需要移除或更换时，需要再次进行手术，因此对肌体组织造成的二次伤害较大。A neurostimulator is a biomedical electronic device. It is used to generate low-frequency electrical pulses to perform functional nerve electrical stimulation on organisms, so as to relieve pain symptoms, restore or adjust nerve or muscle functions, etc. Neurostimulators can be calibrated by neurologists, nurses, or trained technicians to meet the specific needs of individual patients. Implantable neurostimulators are currently the most mature and widely used in the market. This neurostimulator must be surgically implanted into the body of a human or other animal, which has the following limitations: 1) implanting the implantable neurostimulator in the body requires a long period of surgery (such as It takes about twelve hours to implant a deep brain stimulator), and the patient must endure a certain amount of pain; 2) Compared with the specific target nerve that needs to be stimulated, the size of the implantable neurostimulator is relatively large and cannot be implanted To the target nerve or muscle tissue with limited shape or volume (such as the brain); in order to transmit the stimulation signal to the brain, it is necessary to introduce a long electrode extension wire on the electrode; but the electrode extension wire is easy to move , it is possible to trigger an electrical stimulus in the wrong place, which greatly increases the risk of infection. Moreover, infections induced in any part of the implanted neurostimulator tend to spread throughout the system, in which case the battery or the entire implanted neurostimulator must be replaced surgically again; 3) the current market Implantable neurostimulators commonly used in the world are mainly powered by non-rechargeable batteries, and the power will be exhausted within 4 to 10 years. At this time, another operation is required to replace the battery, so its life cycle is short; 4) implantable After the nerve stimulator is implanted in the body, if discomfort occurs, when it needs to be removed or replaced, it needs to be operated again, so the secondary damage to the body tissue is relatively large.
发明内容Contents of the invention
本发明的目的是为了解决和克服上述现有技术，尤其植入式神经刺激器所存在的技术问题和缺陷，提供一种射频能量供电的注射式神经刺激器。本发明的射频能量供电的注射式神经刺激器，目前尚无相关的文献介绍，亦未搜索到相关的专利文件。The purpose of the present invention is to solve and overcome the technical problems and defects of the above-mentioned prior art, especially the implanted nerve stimulator, and provide an injectable nerve stimulator powered by radio frequency energy. The injectable nerve stimulator powered by radio frequency energy of the present invention has no relevant literature introductions, nor has any relevant patent documents been searched.
为实现上述目的，本发明所采取的技术方案是：For realizing above-mentioned purpose, the technical scheme that the present invention takes is:
一种射频能量供电的注射式神经刺激器，由外壳1、电极2、天线3、可充电电池4、微控制器及微神经刺激器模块5、数据接收模块6、射频能量收集模块7、生物及温度传感器8、压力传感器9、眼孔10和填充物11等构成。An injectable neurostimulator powered by radio frequency energy consists of a shell 1, an electrode 2, an antenna 3, a rechargeable battery 4, a microcontroller and a micro neurostimulator module 5, a data receiving module 6, a radio frequency energy collection module 7, a biological And temperature sensor 8, pressure sensor 9, eyelet 10 and filler 11 etc. constitute.
所述外壳1用以保护注射式神经刺激器和人体组织互相免受对方的侵蚀。所述电极2是注射式神经刺激器和生物体组织之间的接口。所述天线3用于数据传输。所述可充电电池4储存所述射频能量收集模块7所收集的电能。所述微控制器及微神经刺激器模块5用于产生、管理和控制注射式神经刺激器的运行；其中微神经刺激器产生一个极性、幅度、占空比和频率可调的脉冲，通过所述电极2对神经或肌肉组织提供适当的电刺激；微控制器用于管理和控制注射式神经刺激器的运行，例如启动或停止刺激，监测神经行为，读取数据信息等。所述数据接收模块6用于解码外部信号发送器所发送的刺激信号信息，如极性、幅度、占空比和频率等。所述射频能量模块7将捕获到的电磁能转换成电能。所述生物及温度传感器8将生物传感器和温度传感器整合在一个模块上；其中前者用于检测神经或肌肉组织的行为，提取电信号和生物体内的生理或生化参数等；后者用于感知注射式神经刺激器的温度以及其和所处组织之间界面处的温度。所述压力传感器9用于测量注射后注射式神经刺激器在体内的压力变化，预警风险。所述眼孔10用以在短期内移除注射式神经刺激器。所述填充物11用于空间填充和部件固定。The shell 1 is used to protect the injectable nerve stimulator and human tissue from being corroded by each other. The electrode 2 is the interface between the injectable nerve stimulator and the biological tissue. The antenna 3 is used for data transmission. The rechargeable battery 4 stores the electric energy collected by the RF energy collection module 7 . The micro-controller and the micro-neurostimulator module 5 are used to generate, manage and control the operation of the injection-type neurostimulator; wherein the micro-neurostimulator generates a pulse with adjustable polarity, amplitude, duty cycle and frequency, through The electrodes 2 provide appropriate electrical stimulation to the nerve or muscle tissue; the microcontroller is used to manage and control the operation of the injectable nerve stimulator, such as starting or stopping stimulation, monitoring nerve behavior, and reading data information. The data receiving module 6 is used for decoding the stimulation signal information sent by the external signal transmitter, such as polarity, amplitude, duty cycle and frequency. The RF energy module 7 converts the captured electromagnetic energy into electrical energy. The biological and temperature sensor 8 integrates a biological sensor and a temperature sensor into one module; the former is used to detect the behavior of nerve or muscle tissue, extract electrical signals and physiological or biochemical parameters in the living body, etc.; the latter is used to sense injection The temperature of the neurostimulator and the temperature at the interface between it and the tissue in which it is placed. The pressure sensor 9 is used to measure the pressure change of the injectable nerve stimulator in the body after injection, so as to warn risks. The eyelet 10 is used for short-term removal of the injectable neurostimulator. The filler 11 is used for space filling and component fixing.
所述外壳1为具有空腔的圆柱体，圆柱体的两端开设有同轴线的一通孔；所述电极2为2根圆柱体，圆柱体的一端套穿连接在外壳1的通孔中，另一延伸端端头为球头；所述天线3为2根，分别并对称涂覆在所述外壳1的内壁上，天线3的一端分别与其中一个所述电极2相连，另一端与所述微控制器及微神经刺激器模块5和射频能量收集模块7相连接，并经电容耦合后连接至数据接收模块6；所述可充电电池4、射频能量收集模块7、微控制器及微神经刺激器模块5、数据接收模块6、生物及温度传感器8和压力传感器9自左至右依次并相互隔离安置在所述外壳1的空腔内；所述可充电电池4的两根电源接头依次以串联的方式连接至所述射频能量收集模块7、微控制器及微神经刺激器模块5、数据接收模块6、生物及温度传感器8和压力传感器9；所述生物及温度传感器8的两路信号，以及所述压力传感器9的一路信号均连接至所述数据接收模块6；所述微控制器及微神经刺激器模块5还有两路信号连接至所述数据接收模块6；所述眼孔10是位于其中一个所述电极2末端实体球中心的通孔；所述眼孔10是在所述2根电极2中的任一根的球头上所开设的孔中心线与电极2轴线相垂直的一通孔。所述填充物11填充所述外壳1内部剩余的空间，并固定其内部所有部件。The housing 1 is a cylinder with a cavity, and a coaxial through hole is opened at both ends of the cylinder; the electrodes 2 are two cylinders, and one end of the cylinder is inserted through and connected to the through hole of the housing 1 , the other end of the extension end is a ball head; the antenna 3 is two, respectively and symmetrically coated on the inner wall of the housing 1, one end of the antenna 3 is connected to one of the electrodes 2, and the other end is connected to the electrode 2. Described microcontroller and microneurostimulator module 5 are connected with radio frequency energy harvesting module 7, and are connected to data receiving module 6 after capacitive coupling; Described rechargeable battery 4, radio frequency energy harvesting module 7, microcontroller and The micro-nerve stimulator module 5, the data receiving module 6, the biological and temperature sensor 8 and the pressure sensor 9 are sequentially arranged in the cavity of the housing 1 from left to right; the two power supplies of the rechargeable battery 4 The joint is connected to the radio frequency energy collection module 7, the microcontroller and the microneurostimulator module 5, the data receiving module 6, the biological and temperature sensor 8 and the pressure sensor 9 in series in sequence; Two-way signal, and one-way signal of described pressure sensor 9 are all connected to described data receiving module 6; Described microcontroller and micro-nerve stimulator module 5 also have two-way signal to be connected to described data receiving module 6; Described eye hole 10 is the through hole that is positioned at the solid ball center of one of them described electrode 2 end; 2 through holes perpendicular to each other. The filler 11 fills the remaining space inside the casing 1 and fixes all the components inside it.
上述外壳1用具有生物兼容性的材料制造，如陶瓷或玻璃中任一种，优选陶瓷；其外径小于相对应的注射针头的内径。The above shell 1 is made of biocompatible materials, such as any one of ceramics or glass, preferably ceramics; its outer diameter is smaller than the inner diameter of the corresponding injection needle.
上述电极2用具有生物兼容性的导体制造，如铂、铂-铱合金、氧化铱、氮化钛、蚕丝中任一种，优选铂；上述电极2的直径小于上述外壳1的内径；其末端球头的直径大于其圆柱体的直径。The above-mentioned electrode 2 is made of a biocompatible conductor, such as any one of platinum, platinum-iridium alloy, iridium oxide, titanium nitride, and silk, preferably platinum; the diameter of the above-mentioned electrode 2 is smaller than the inner diameter of the above-mentioned shell 1; its end The diameter of the ball head is larger than the diameter of its cylinder.
上述的天线3由金属微带线制造。The aforementioned antenna 3 is made of metal microstrip lines.
上述的可充电电池4应采用具有高能量的可充电电池，如锂离子电池等。Above-mentioned rechargeable battery 4 should adopt the rechargeable battery with high energy, as lithium ion battery etc.
上述的可充电电池4、微控制器及微神经刺激器模块5、数据接收模块6、射频能量收集模块7、生物及温度传感器8、压力传感器9之间的信号由金属键合线相连。The signals among the above-mentioned rechargeable battery 4, microcontroller and micro-neurostimulator module 5, data receiving module 6, radio frequency energy collection module 7, biological and temperature sensor 8, and pressure sensor 9 are connected by metal bonding wires.
上述眼孔9的直径小于所述电极2的球头的直径。The diameter of the eye hole 9 is smaller than the diameter of the ball head of the electrode 2 .
上述的填充物11为环氧树脂或凝胶中任一种，优选环氧树脂。The above-mentioned filler 11 is any one of epoxy resin or gel, preferably epoxy resin.
本发明的一种射频能量供电的注射式神经刺激器与现有技术相比具有如下优点和有益效果：Compared with the prior art, a radiofrequency energy-powered injectable nerve stimulator of the present invention has the following advantages and beneficial effects:
1、由于本发明的一种射频能量供电的注射式神经刺激器的尺寸很小，所以可以通过注射器将其注射至靶点神经或肌肉组织中，且可以选用中小口径的注射针头(如16G及以下)，以减小注射过程中对活体肌肉组织或神经的损伤；1. Since the injectable nerve stimulator powered by radio frequency energy of the present invention has a very small size, it can be injected into the target nerve or muscle tissue through a syringe, and small and medium-caliber injection needles (such as 16G and Below), in order to reduce the damage to living muscle tissue or nerve during injection;
2、由于本发明的一种射频能量供电的注射式神经刺激器可以注射至植入式神经刺激器所不能达到的靶点神经或肌肉组织中，因此不需要电极延长导线，从而极大降低了感染的风险；2. Since the injectable nerve stimulator powered by radio frequency energy of the present invention can be injected into the target nerve or muscle tissue that cannot be reached by the implanted nerve stimulator, there is no need for electrode extension wires, thereby greatly reducing the risk of infection;
3、由于本发明的一种射频能量供电的注射式神经刺激器采用射频能量供电，其能量是无线传输的，且可以储存在可充电电池中，因此不需要更换电池，全寿命周期长。3. Since the injectable nerve stimulator powered by radio frequency energy of the present invention is powered by radio frequency energy, its energy is transmitted wirelessly and can be stored in a rechargeable battery, so there is no need to replace the battery, and the whole life cycle is long.
4、由于本发明的一种射频能量供电的注射式神经刺激器具有眼孔，因此在注射的初期如果发生不适，可以在原创口处进行快捷移除，对肌体组织造成的二次伤害小。4. Since the radiofrequency energy-powered injectable nerve stimulator of the present invention has an eye hole, if discomfort occurs at the initial stage of injection, it can be quickly removed at the original opening, causing little secondary damage to the body tissue.
附图说明Description of drawings
图1是本发明的构造示意图；Fig. 1 is a structural representation of the present invention;
图2是电极2、天线3与微控制器及微神经刺激器模块5、数据接收模块6和射频能量收集模块7之间的接口信号连接示意图；Fig. 2 is the interface signal connection schematic diagram between electrode 2, antenna 3 and microcontroller and microneurostimulator module 5, data receiving module 6 and radio frequency energy collection module 7;
图3是可充电电池4与微控制器及微神经刺激器模块5、数据接收模块6、射频能量收集模块7、生物及温度传感器8和压力传感器9之间的电源信号连接示意图；Fig. 3 is a schematic diagram of the power supply signal connection between the rechargeable battery 4 and the microcontroller and the microneurostimulator module 5, the data receiving module 6, the radio frequency energy collection module 7, the biological and temperature sensor 8 and the pressure sensor 9;
图4是微控制器及微神经刺激器模块5、数据接收模块6、生物及温度传感器8和压力传感器9之间的数据信号连接示意图。FIG. 4 is a schematic diagram of the data signal connection between the microcontroller and the microneurostimulator module 5 , the data receiving module 6 , the biological and temperature sensor 8 and the pressure sensor 9 .
图中：1.外壳，2.电极，3.天线，4.可充电电池，5.微控制器及微神经刺激器模块，6.数据接收模块，7.射频能量收集模块，8.生物及温度传感器，9.压力传感器，10.眼孔，11.填充物。In the figure: 1. Shell, 2. Electrode, 3. Antenna, 4. Rechargeable battery, 5. Microcontroller and micro-neurostimulator module, 6. Data receiving module, 7. RF energy harvesting module, 8. Biological and Temperature sensor, 9. Pressure sensor, 10. Eye hole, 11. Filling.
具体实施方式Detailed ways
为了加深对本发明的理解，下面结合实施例和附图对本发明作进一步的详述，该实施例仅用于解释本发明，并不构成对本发明保护范围的规定。In order to deepen the understanding of the present invention, the present invention will be described in further detail below in conjunction with the examples and accompanying drawings. The examples are only used to explain the present invention, and do not constitute regulations on the protection scope of the present invention.
本发明中所述的“内、外”的含义指的是相对于神经刺激器本身而言，指向神经刺激器内部的方向为内，反之为外，而非对本发明的神经刺激器的特定限定。The meaning of "inner and outer" mentioned in the present invention refers to that relative to the neurostimulator itself, the direction pointing to the interior of the neurostimulator is inward, and vice versa, it is not a specific limitation to the neurostimulator of the present invention .
本发明中所述的“左、右”的含义指的是阅读者正对附图时，阅读者的左边即为左，阅读者的右边即为右，而非对本发明的神经刺激器的特定限定。The meaning of "left and right" mentioned in the present invention refers to that when the reader is facing the accompanying drawings, the left side of the reader is the left, and the right side of the reader is the right, rather than specific to the neurostimulator of the present invention. limited.
本发明中所述的“连接”的含义可以是部件之间的直接连接也可以是部件间通过其它部件的间接连接。The meaning of "connection" in the present invention may be a direct connection between components or an indirect connection between components through other components.
如图1，图2，图3和图4所示，一种射频能量供电的注射式神经刺激器，由外壳1、电极2、天线3、可充电电池4、微控制器及微神经刺激器模块5、数据接收模块6、射频能量收集模块7、生物及温度传感器8、压力传感器9、眼孔10和填充物11等构成。所述外壳1为具有空腔的圆柱体，其外径(Φ1)为1毫米，内径为0.9毫米，长度(L1)为4毫米，由陶瓷制造；所述陶瓷外壳1圆柱体的两端开设有同轴线直径为0.42毫米的一通孔，通孔中各放置一个封口用的陶瓷帽。所述电极2由直径(Φ21)0.4毫米、长度0.4毫米的圆柱体和末端直径为(Φ22)0.6毫米的球头构成，均采用金属铂制造；两个所述铂电极2圆柱体的末端分别套在所述外壳1陶瓷帽的圆孔内以构成正电极和负电极，并采用以氧化铝为主要原料的金属陶瓷密封环密封。所述天线3由两根宽度为200微米、厚度为50微米的微带线制造，采用金属银对称沉积在外壳1的内壁上，呈“S”形；每根所述天线3的一个接头焊接在所述电极2圆柱体的末端，另一端通过金属键合线连接至所述微控制器及微神经刺激器模块5(NS_OUT+和NS_OUT-)和射频能量收集模块7(RF_RX+和RF_RX-)，并经电容耦合后(DATA_RX+和DATA_RX-)连接至数据接收模块6，如图2所示。所述可充电电池4采用美国Qullion公司制造的注射式锂离子可充电电池，其直径为0.8毫米，长度为3毫米；所述可充电电池4安置于所述外壳1内部圆柱体的左半边。所述微控制器及微神经刺激器模块5、数据接收模块6、射频能量收集模块7、生物及温度传感器8、压力传感器9等功能模块自左至右依次并隔离安置于球体的右半边，且均采用基于90纳米的CMOS工艺制造，其相互之间的信号通过金属键合线相连。所述可充电电池4的两根电源接头(BAT+和BAT-)依次以串联的方式连接至所述射频能量收集模块7、微控制器及微神经刺激器模块5、数据接收模块6、生物及温度传感器8和压力传感器9，如图3所示。所述微控制器及微神经刺激器模块4和数据接收模块5之间通过I2C总线(SDA和SCL)通信；所述生物及温度传感器8所感知的生物信号(BIO)和温度信号(TEMP)，以及所述压力传感器9所感知的压力信号(PRESSURE)均输入所述数据接收模块6，如图4所示。所述眼孔10是在所述2根电极2中的任一根的球头上所开设的孔中心线与电极2轴线相垂直的一通孔，其直径(Φ10)为0.1毫米。所述填充物11采用环氧树脂，填充所述外壳1内部剩余的空间，并固定其内部所有其它部件。在将所有部件装入所述外壳1内后，将所述外壳1的陶瓷帽套在其圆柱体的末端上封口，并用O形陶瓷密封圈和陶瓷密封胶密封。As shown in Fig. 1, Fig. 2, Fig. 3 and Fig. 4, an injectable neurostimulator powered by radio frequency energy consists of a shell 1, an electrode 2, an antenna 3, a rechargeable battery 4, a microcontroller and a microneurostimulator module 5, data receiving module 6, radio frequency energy collection module 7, biological and temperature sensor 8, pressure sensor 9, eye hole 10 and filler 11, etc. The shell 1 is a cylinder with a cavity, its outer diameter (Φ1) is 1 mm, its inner diameter is 0.9 mm, and its length (L1) is 4 mm, made of ceramics; the two ends of the ceramic shell 1 cylinder are opened There is a through hole with a coaxial diameter of 0.42 mm, and a ceramic cap for sealing is placed in each of the through holes. The electrode 2 is composed of a cylinder with a diameter of (Φ21) 0.4 mm and a length of 0.4 mm and a ball head with a diameter of (Φ22) 0.6 mm at the end, all made of metal platinum; the ends of the two platinum electrodes 2 cylinders are respectively The positive electrode and the negative electrode are set in the circular hole of the ceramic cap of the shell 1, and are sealed with a cermet sealing ring with alumina as the main raw material. The antenna 3 is made of two microstrip lines with a width of 200 microns and a thickness of 50 microns, and metal silver is symmetrically deposited on the inner wall of the housing 1 in an "S"shape; a joint of each antenna 3 is welded At the end of the cylinder of the electrode 2, the other end is connected to the microcontroller and the micro-neurostimulator module 5 (NS_OUT+ and NS_OUT-) and the radio frequency energy collection module 7 (RF_RX+ and RF_RX-) through a metal bonding wire, And after capacitive coupling (DATA_RX+ and DATA_RX-), connect to the data receiving module 6, as shown in FIG. 2 . The rechargeable battery 4 is an injection-type lithium-ion rechargeable battery manufactured by the U.S. company Qullion, which has a diameter of 0.8 mm and a length of 3 mm; Functional modules such as the microcontroller and micro-neurostimulator module 5, the data receiving module 6, the radio frequency energy collection module 7, the biological and temperature sensor 8, and the pressure sensor 9 are sequentially and isolatedly placed on the right half of the sphere from left to right, And all adopt the CMOS process based on 90 nanometers to manufacture, and the signals between them are connected by metal bonding wires. The two power connectors (BAT+ and BAT-) of the rechargeable battery 4 are sequentially connected in series to the radio frequency energy harvesting module 7, microcontroller and microneurostimulator module 5, data receiving module 6, biological and The temperature sensor 8 and the pressure sensor 9 are shown in FIG. 3 . The microcontroller and the microneurostimulator module 4 and the data receiving module 5 communicate through the I2 C bus (SDA and SCL); the biological signal (BIO) and the temperature signal (BIO) sensed by the biological and temperature sensor 8 ( TEMP) and the pressure signal (PRESSURE) sensed by the pressure sensor 9 are input into the data receiving module 6, as shown in FIG. 4 . The eyehole 10 is a through hole whose center line of the hole provided on the ball head of any one of the two electrodes 2 is perpendicular to the axis of the electrode 2, and its diameter (Φ10) is 0.1 mm. The filler 11 uses epoxy resin to fill the remaining space inside the housing 1 and fix all other components inside it. After all components are packed into the housing 1, the ceramic cap of the housing 1 is sealed on the end of its cylinder, and sealed with O-shaped ceramic sealing ring and ceramic sealant.
以上实施例，仅为本发明较佳的具体实施方式。当然，本发明还可有其它多种实施例，在不背离本发明精神及其实质的情况下，任何熟悉本技术领域的技术人员，当可根据本发明作出各种相应的等效设计，都应属于本发明所附的权利要求的保护范围。The above embodiments are only preferred specific implementation modes of the present invention. Certainly, the present invention also can have other various embodiments, under the situation of not departing from the spirit and essence of the present invention, any person familiar with this technical field, when can make various corresponding equivalent designs according to the present invention, all Should belong to the scope of protection of the appended claims of the present invention.
本发明的一种射频能量供电的注射式神经刺激器的直径和长度都很小，可以通过注射器并选用中小口径的注射针头(如16G及以下)，将其直接注射至植入式神经刺激器所不能达到的靶点神经或肌肉组织中，并可以快捷移除。本发明适用于需要较低脉冲幅度刺激的场合。The diameter and length of a radio frequency energy-powered injection neurostimulator of the present invention are very small, and can be directly injected into the implantable neurostimulator through a syringe and a small and medium-caliber injection needle (such as 16G and below). In the target nerve or muscle tissue that cannot be reached, it can be removed quickly. The invention is suitable for occasions requiring stimulation with lower pulse amplitude.
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510020720.9ACN104548344B (en) | 2015-01-16 | 2015-01-16 | Injection type nerve stimulator with power supplied by radio frequency energy |
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510020720.9ACN104548344B (en) | 2015-01-16 | 2015-01-16 | Injection type nerve stimulator with power supplied by radio frequency energy |
| Publication Number | Publication Date |
|---|---|
| CN104548344Atrue CN104548344A (en) | 2015-04-29 |
| CN104548344B CN104548344B (en) | 2017-02-22 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510020720.9AActiveCN104548344B (en) | 2015-01-16 | 2015-01-16 | Injection type nerve stimulator with power supplied by radio frequency energy |
| Country | Link |
|---|---|
| CN (1) | CN104548344B (en) |
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