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CN104207780A - Measuring device and measuring method for judgment of lower limb flexibility of parkinsonian - Google Patents

Measuring device and measuring method for judgment of lower limb flexibility of parkinsonian
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CN104207780A
CN104207780ACN201410416108.9ACN201410416108ACN104207780ACN 104207780 ACN104207780 ACN 104207780ACN 201410416108 ACN201410416108 ACN 201410416108ACN 104207780 ACN104207780 ACN 104207780A
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flexibility
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徐仁伵
邓霞
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Nanchang University
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Abstract

Translated fromChinese

本发明公开了用于帕金森病患者下肢灵活度的测量装置,包括控制板、脚踏垫、光电感应装置、时间控制秒表、显示屏、电池装置、时间增减按钮、测试开关及启停按钮;本发明能够较准确地为患者的下肢灵活度进行等级判断,能大幅度提高本项目测定的下肢灵活度的精确度,从而提高UPDRS中运动功能部分的分数测定的精度与可靠性;不仅能系统且主动地对具有帕金森病患者的下肢灵活度进行准确的测定,而且能准确地为后续分析提供可靠依据;同时,由于提供了带有有效足跟抬高次数的显示屏,可以精密地给出设定时间内足跟抬高的有效次数。

The invention discloses a measuring device for the flexibility of the lower limbs of patients with Parkinson's disease, which includes a control board, a foot pad, a photoelectric induction device, a time control stopwatch, a display screen, a battery device, time increase and decrease buttons, a test switch and a start-stop button ; The present invention can more accurately carry out grade judgment for the flexibility of the lower limbs of the patient, can greatly improve the accuracy of the flexibility of the lower limbs measured by this project, thereby improving the accuracy and reliability of the score measurement of the motor function part in the UPDRS; not only can Systematically and proactively measure the flexibility of the lower limbs of patients with Parkinson's disease, and can accurately provide a reliable basis for subsequent analysis; at the same time, because it provides a display screen with effective heel raising times, it can precisely measure Gives the effective number of heel lifts within the set time.

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Translated fromChinese
一种用于帕金森病患者下肢灵活度判定的测量装置及方法A measuring device and method for judging flexibility of lower limbs of patients with Parkinson's disease

技术领域technical field

本发明涉及一种评级装置,尤其涉及一种专用于帕金森病患者下肢灵活度判定的测量装置,更进一步涉及实验时对帕金森病人进行国际用统一帕金森病评定量表第三部分中第26项目对下肢灵活度评定中所需用的测量装置。The present invention relates to a rating device, in particular to a measuring device specially used for judging the lower limb flexibility of patients with Parkinson's disease, and further relates to the third part of the International Unified Parkinson's Disease Rating Scale for Parkinson's patients during experiments. 26 items are the measuring devices required in the assessment of the flexibility of the lower limbs.

背景技术Background technique

帕金森病是一种中老年神经退行性疾病,其临床特征通常表现为静止性震颤、运动迟缓、肌张力增高和姿势平衡障碍,其病理特点主要有三点:(1)选择性中脑黑质多巴胺能神经元丧失;(2)纹状体多巴胺含量显著减少;(3)黑质及蓝斑出现路易小体;Parkinson's disease is a neurodegenerative disease of middle-aged and elderly people. Its clinical features are usually resting tremor, bradykinesia, increased muscle tone, and postural balance disorder. There are three main pathological features: (1) Selective substantia nigra Loss of dopaminergic neurons; (2) significantly decreased dopamine content in striatum; (3) Lewy bodies appeared in substantia nigra and locus coeruleus;

目前,对于帕金森病的诊断,通常是采用帕金森病的国际通用临床诊断标准进行诊断:具体的判断标准如下:(1)静止性震颤、运动迟缓、齿轮样肌强直和姿势性反射障碍,一个帕金森病患者至少需要具有静止性震颤、运动迟缓两项中之一的特征;(2)病人的帕金森病症状和体征不是由于脑外伤、脑血管疾病、脑肿瘤、病毒感染或其他已知的神经系统疾病,以及已知的药物和化学毒物所引起的;(3)病人必须具备以下体征:明显的核上性共视运动障碍、小脑症、核性发音障碍、体位性低血压(改变超过30mmHg以上)、锥体性损害及肌萎缩;(4)左旋多巴制剂试验有效;同时满足上述四项标准的病人可临床诊断为帕金森病;但是经过此临床标准诊断出的帕金森病人与病理诊断的一致性只有70%-75%,其特异性并不高;在临床研究和流行病学研究中,为尽量保证诊断的准确性,除要求病人符合上述四项标准外,还需要满足病人的症状及体征在初发时或病程中是否有不对称得表现,若病人出现不对称表现在帕金森病的诊断特异性将显著提高到90%左右;At present, the diagnosis of Parkinson's disease is usually made using the international general clinical diagnostic criteria for Parkinson's disease: the specific criteria are as follows: (1) resting tremor, bradykinesia, gear-like muscle rigidity and postural reflex disorder, A patient with Parkinson's disease needs to have at least one of the characteristics of resting tremor and slow movement; (2) The patient's symptoms and signs of Parkinson's disease are not due to traumatic brain injury, cerebrovascular disease, brain tumor, viral infection or other (3) The patient must have the following signs: obvious supranuclear synoptic dyskinesia, cerebellar disease, nuclear dysphonia, orthostatic hypotension ( change over 30mmHg), pyramidal damage and muscle atrophy; (4) levodopa preparation test is effective; patients who meet the above four criteria at the same time can be clinically diagnosed as Parkinson's disease; but Parkinson's disease diagnosed by this clinical standard The consistency between the patient and the pathological diagnosis is only 70%-75%, and its specificity is not high; It is necessary to meet whether the patient's symptoms and signs have asymmetrical manifestations at the initial onset or during the course of the disease. If the patient has asymmetrical manifestations, the diagnostic specificity of Parkinson's disease will be significantly increased to about 90%;

然而上述帕金森病的临床症状主要以运动症状为主,但仍存在非运动症状,非运动症状主要包括(1)精神症状,具体体现在注意力缺陷;人格、认识障碍;视觉(视空间感知障碍、颜色辨别能力受损)、意识障碍;抑郁;淡漠;缺乏快感;激越;躁狂;焦虑;视幻觉;计算力、记忆力、定向力、判断力丧失;(生理)错觉;痴呆;认知损害(智力功能、心理运动控制、高水平认知功能及认知可塑性的异常);生动的梦境;(2)自主神经症状,主要表现在便秘、体位性低血压、出汗、性功能障碍、排尿障碍、流涎;(3)感觉障碍,主要表现在麻木、疼痛、痉挛、不宁腿综合症(RLS)、嗅觉丧失;(4)睡眠障碍,具体表现在失眠、不安腿综合症(RLS)、周期性肢体运动(PLM)、快速眼动(REM)睡眠、非快速眼动睡眠、行为障碍、白日嗜睡;However, the above-mentioned clinical symptoms of Parkinson's disease are mainly motor symptoms, but there are still non-motor symptoms. The non-motor symptoms mainly include (1) mental symptoms, which are specifically reflected in attention deficit; impairment of color discrimination), disturbance of consciousness; depression; apathy; anhedonia; agitation; mania; anxiety; visual hallucinations; loss of calculation, memory, orientation, judgment; (physiological) illusions; dementia; cognition Impairment (abnormalities of intellectual function, psychomotor control, high-level cognitive function, and cognitive plasticity); vivid dreams; (2) autonomic symptoms, mainly manifested in constipation, postural hypotension, sweating, sexual dysfunction, Urination disorders, salivation; (3) sensory disturbances, mainly manifested in numbness, pain, cramps, restless legs syndrome (RLS), loss of smell; (4) sleep disturbances, specifically manifested in insomnia, restless legs syndrome (RLS) , periodic limb movement (PLM), rapid eye movement (REM) sleep, non-REM sleep, behavioral disturbance, daytime sleepiness;

因此,对于PD的运动症状和非运动症状应采取综合治疗,包括药物治疗、手术治疗、康复治疗、心理治疗及护理等;药物治疗作为首选,是整个治疗过程中的主要治疗手段,而手术治疗则是药物治疗的一种有效补充手段;目前应用的治疗手段,无论是药物或手术,都只能改善症状而不能阻止病情的发展,更无法治愈;对帕金森病人的治疗,以达到有效改善症状,提高生活质量为目标,坚持“剂量滴定“、“以最小剂量达到满意效果”;治疗应该根据个体化特点不同而不同;因此,对PD症状的确定,可以明确病情是得到改善还是进一步恶化,并与治疗方案的选择和确定有着重大而密切的关系;Therefore, comprehensive treatment should be adopted for the motor symptoms and non-motor symptoms of PD, including drug therapy, surgical treatment, rehabilitation therapy, psychological therapy and nursing care; drug therapy is the first choice and is the main treatment in the whole treatment process, while surgical treatment It is an effective supplementary means of drug therapy; the current treatment methods, whether drugs or surgery, can only improve the symptoms but cannot prevent the development of the disease, let alone cure; the treatment of Parkinson's patients, in order to achieve effective improvement Symptoms, improve the quality of life as the goal, adhere to "dose titration" and "achieve satisfactory results with the smallest dose"; treatment should be different according to individual characteristics; therefore, the determination of PD symptoms can clearly determine whether the condition is improved or further deteriorated , and has a significant and close relationship with the selection and determination of treatment options;

对帕金森病人所处阶段的判定,国际上普遍采用统一帕金森病评定量表(Unified Parkinson’s Disease Rating Scal, UPDRS)来评估;分值越高,PD症状越严重; UPDRS 是用来概括测量帕金森病人各个方面能力的统一量表,共分三部分:第一部分:精神、行为和情绪(包括测试项目1-4);第二部分:日常活动(包括测试项目5-17,由患者填写);第三部分:运动功能(包括测试项目18-31,医生检查);第四部分:治疗的并发症(包括测试项目32-42,指上周);To determine the stage of Parkinson's patients, the Unified Parkinson's Disease Rating Scale (UPDRS) is generally used in the world to evaluate; the higher the score, the more severe the symptoms of PD; UPDRS is used to generalize the measurement of Parkinson's disease. The unified scale of Jinsen patients' ability in various aspects is divided into three parts: the first part: mental, behavioral and emotional (including test items 1-4); the second part: daily activities (including test items 5-17, to be filled out by the patient) ;Part III: Motor function (including test items 18-31, doctor’s examination); Part IV: Complications of treatment (including test items 32-42, referring to last week);

然而,在实际使用UPDRS中,却面临着重重难关,主要是一些项目的界定标准不统一,导致其准确评价造成极大的困难;在这四个部分中,第一、二、四部分多数项目的测试有固定量化标准,较容易测量,而第三部分的一些项目的测试标准较模糊,并且一些量化的标准由检查者在多次不同场合中进行测量时来维持固定比较困难;其中,第三部分的第26项检测项目为下肢灵活度,主要是膝关节屈曲状态下腿的灵活性,主要是指快速反复踮起足跟使腿抬起,足跟抬高至少6cm;通常有五种状态显示:(1)0表示正常状态;(2)1表示动作轻度减慢或幅度轻度变小;(3)2表示中度损害;主要症状表现有早衰,可有间歇,即幅度减少,易于疲劳,动作中偶尔有暂停;(4)3表示严重损害,包括启动困难、中途间歇,即动作开始时犹豫,动作进行中有暂停现象;(5)4表示几乎不能完成测试;However, in the actual use of UPDRS, there are many difficulties. The main reason is that the definition standards of some projects are not uniform, which leads to great difficulties in its accurate evaluation; among these four parts, most of the projects in the first, second and fourth parts There are fixed quantitative standards in the tests, which are easier to measure, while the test standards of some items in the third part are more vague, and some quantitative standards are difficult to maintain when the inspectors measure in multiple different occasions; among them, the first The 26th test item in the three parts is the flexibility of the lower limbs, mainly the flexibility of the legs under the knee joint flexion state, mainly refers to the rapid and repeated tipping of the heels to lift the legs, and the heel is raised by at least 6cm; usually there are five states Display: (1) 0 indicates a normal state; (2) 1 indicates a slight slowing down of the movement or a slight decrease in the range; (3) 2 indicates moderate damage; the main symptoms are premature aging, and there may be intervals, that is, the amplitude is reduced, Easy to fatigue, with occasional pauses in the movement; (4) 3 means serious impairment, including difficulty in starting, intermittence in the middle, that is, hesitation at the beginning of the movement, and pauses during the movement; (5) 4 means that the test can hardly be completed;

根据该表分析,准确测量下肢灵活度的条件包括:1、项目测试的标准动作为快速反复踮起足跟使腿抬起,且足跟太高至少6cm;2、测试过程没有时间限制;3、对下肢灵活度的评定分为5个级别:正常;轻度障碍;明显障碍;严重障碍;几乎不能完成;根据该表进行帕金森病的判定,主要是根据这5个级别的评定依据观察测试者的情况;然而,对测试者的观察往往没有固定、量化的标准依据;因此,对于同一个病人,不同时间段的测试没有统一的标准,对于多个甚至大批患者的评定也没有统一的评价标准,而不同的实验,不同的测试员对患者进行该项目测试的标准更是没有统一的标准;即便在同一个试验中,测试者由于不同时间里具有不同的状态,不同状态下的标准很不恒定,将可能导致测试结果与实验中患者的实际情况产生严重偏差;对不同实验相对比时,由于标准不可控,此偏移将可能更大;According to the table analysis, the conditions for accurately measuring the flexibility of the lower limbs include: 1. The standard action of the project test is to quickly and repeatedly lift the heel to lift the leg, and the heel is at least 6cm too high; 2. There is no time limit for the test process; 3. 1. The assessment of the flexibility of the lower limbs is divided into 5 levels: normal; mild impairment; obvious impairment; severe impairment; almost impossible to complete; the judgment of Parkinson's disease according to this table is mainly based on the evaluation of these 5 levels based on observation However, there is often no fixed and quantitative standard basis for the observation of testers; therefore, for the same patient, there is no unified standard for testing in different time periods, and there is no unified standard for the evaluation of multiple or even a large number of patients Evaluation standards, and in different experiments, different testers have no uniform standards for testing patients on this item; even in the same test, testers have different states at different times, and the standards in different states It is very inconstant, which may lead to a serious deviation between the test results and the actual situation of the patients in the experiment; when comparing different experiments, due to uncontrollable standards, the deviation may be larger;

由于以上传统测试方法存在种种缺陷,不能精确且无法对患者的下肢灵活度下降的程度或发展进程做出准确的确认,将导致第26项目的测试失误,进而导致运动功能以致UPRDS第三部分评分的失误,继而导致后续相关性分析的失误;Due to the various defects of the above traditional testing methods, it is not accurate and cannot accurately confirm the degree of decline in the flexibility of the lower limbs or the development process of the patient, which will lead to test errors in the 26th item, which will lead to motor function and UPRDS Part III scores mistakes, which in turn lead to mistakes in subsequent correlation analysis;

为满足高精度试验中对测量的准确要求,我们设计了一种专门用于帕金森病患者下肢灵活度判定的测试装置,提高测试的精准度。In order to meet the accurate requirements for measurement in high-precision tests, we have designed a test device specially used to determine the flexibility of the lower limbs of patients with Parkinson's disease to improve the accuracy of the test.

发明内容Contents of the invention

本发明为了弥补现有技术的不足,提供一种结构简单的专用于帕金森病患者下肢灵活度判定的测量装置,该装置能够标准、精确地计量数据,有效地避免在短暂的时间里计数不准确、评分不准的结果,大大提高了帕金森病项目测试结构的精确度和可靠度;本发明的另一目的在于提供一种利用该装置进行帕金森病患者下肢灵活度的测量方法,该方法主要是利用简易编程控制时程、利用简易编程计数踮起足跟的有效次数,避免在短暂的时间里计数不准、评分不准的结果,从而大大提高本项目测试结果的精确度和可靠度。In order to make up for the deficiencies of the prior art, the present invention provides a measuring device with simple structure specially used for judging the flexibility of the lower limbs of patients with Parkinson's disease. Accurate and inaccurate results greatly improve the accuracy and reliability of the Parkinson's disease project test structure; another object of the present invention is to provide a method for measuring the flexibility of the lower limbs of patients with Parkinson's disease using the device. The method is mainly to use simple programming to control the time course, and use simple programming to count the effective times of standing on tiptoe to avoid the results of inaccurate counting and inaccurate scoring in a short period of time, thereby greatly improving the accuracy and reliability of the test results of this project Spend.

为实现上述发明目的,本发明采用如下的技术方案:In order to realize the above-mentioned purpose of the invention, the present invention adopts following technical scheme:

一种用于帕金森病患者下肢灵活度的测量装置,包括控制板、脚踏垫、光电感应装置、时间控制秒表、显示屏、电池装置、时间增减按钮、测试开关及启停按钮;其特征在于:A device for measuring the flexibility of the lower limbs of patients with Parkinson's disease, including a control panel, a foot pad, a photoelectric sensor device, a time control stopwatch, a display screen, a battery device, time increase and decrease buttons, a test switch and a start-stop button; Features:

所述控制板设置在脚踏垫的内部,用于实现装置各种操作的控制功能;The control board is arranged inside the foot pad, and is used to realize the control functions of various operations of the device;

所述光电感应装置设置在脚踏垫上,且位于前端设置,与脚踏垫内部的控制板电连接,用于判定测试者的足跟抬起高度是否达到6cm;The photoelectric sensing device is arranged on the foot pad, and is located at the front end, and is electrically connected to the control board inside the foot pad, and is used to determine whether the heel lift height of the tester reaches 6cm;

所述时间控制秒表设置在显示屏的上端,用于控制测试时程控制,并发出测试终止讯息;The time control stopwatch is set on the upper end of the display screen, used to control the test schedule control, and send a test termination message;

所述显示屏设置在脚踏垫的尾部上端,与控制板电连接,用于显示评级级数、计量次数、计量时间;The display screen is arranged on the upper end of the tail of the foot pad, and is electrically connected to the control panel, and is used to display the rating series, the number of times of measurement, and the time of measurement;

所述时间增减按钮设置在显示屏的左侧,分别与控制板、显示屏点连接;用于设定测试时间的长短;The time increase and decrease buttons are arranged on the left side of the display screen, respectively connected to the control panel and the display screen; used to set the length of the test time;

所述电池装置设置在显示屏的左侧,且靠近时间增减按钮的尾端,用于给整个装置供电;The battery device is arranged on the left side of the display screen, and is close to the tail end of the time increase and decrease buttons, and is used to supply power to the whole device;

所述启动按钮设置在显示屏的右侧,分别控制板、显示屏连接,用于启动整个装置;The start button is arranged on the right side of the display screen, connected to the control board and the display screen respectively, and is used to start the whole device;

所述测试按钮设置在显示屏的右侧,且靠近脚踏垫的尾端,用于控制下肢测试的启停;The test button is arranged on the right side of the display screen, and is close to the tail end of the foot pad, and is used to control the start and stop of the lower limb test;

进一步改进,所述控制板包括控制模块、显示模块、开关模块、电源模块、时间设定模块、光电感应控制模块及时间控制模块;所述开关模块、显示模块、电源模块、时间设定模块、光电感应控制模块及时间控制模块均为控制模块电连接;所述开关模块分别与启停按钮、测试开关电连接;所述显示模块与显示屏电连接;所述时间设定模块与时间增减按钮连接,实现时间增加或减少的设定;所述电源模块与电池专职电连接,用于给测量装置提供电源;所述光电感应控制模块与光电感应装置电连接,控制两个光电感应装置进行光源相互对射、感应;所述时间控制模块与时间控制秒表电连接,用于控制时间秒表时间的设定及控制;As a further improvement, the control board includes a control module, a display module, a switch module, a power supply module, a time setting module, a photoelectric sensor control module and a time control module; the switch module, the display module, the power supply module, the time setting module, Both the photoelectric induction control module and the time control module are electrically connected to the control module; the switch module is electrically connected to the start-stop button and the test switch respectively; the display module is electrically connected to the display screen; the time setting module is connected to the time increase and decrease The button is connected to realize the setting of time increase or decrease; the power module is electrically connected with the battery to provide power to the measuring device; the photoelectric sensor control module is electrically connected to the photoelectric sensor device to control the two photoelectric sensor devices. The light sources meet and sense each other; the time control module is electrically connected with the time control stopwatch, and is used for setting and controlling the time of the time control stopwatch;

所述控制模块为可写入控制程序的中央处理器;The control module is a central processing unit that can be written into a control program;

进一步改进,所述踏脚板包括踏板及支撑板;所述踏板设置在支撑板上,与支撑板插接固定;As a further improvement, the tread plate includes a pedal and a support plate; the pedal is arranged on the support plate, and is plugged and fixed with the support plate;

进一步改进,所述踏板为塑料踏板;其长度为40cm、宽度为20cm、厚度为0.5cm;As a further improvement, the pedal is a plastic pedal; its length is 40cm, width is 20cm, and thickness is 0.5cm;

进一步改进,所述支撑板为橡胶支撑板;As a further improvement, the support plate is a rubber support plate;

进一步改进,所述时间增减按钮包括增加按钮及减少按钮;所述增加按钮用“+”表示;所述减少按钮用“-”表示;As a further improvement, the time increase and decrease buttons include an increase button and a decrease button; the increase button is represented by "+"; the decrease button is represented by "-";

进一步改进, 所述光电感应开关为一对对射式红外线光电开关;其中一个为红外线发射器;另一个为红外线接收器;As a further improvement, the photoelectric sensor switch is a pair of through-beam infrared photoelectric switches; one of them is an infrared transmitter; the other is an infrared receiver;

进一步改进,所述时间控制秒表为具有编程程序的秒表;As a further improvement, the time-controlled stopwatch is a stopwatch with a programming program;

进一步改进,所述时间控制秒表内设有报警单元,用于发出测量终止报警信号,终止测量;As a further improvement, the time control stopwatch is provided with an alarm unit for sending a measurement termination alarm signal to terminate the measurement;

利用上述装置进行下肢灵活度的测量方法,具体步骤如下:Using the above device to measure the flexibility of the lower limbs, the specific steps are as follows:

步骤一:测量前检查,检测测量装置运行是否正常;显示屏的显示是否清晰,电池的电量是否冲出,各部件是否齐全、其工作性能是否良好;Step 1: Check before measurement to check whether the measuring device is operating normally; whether the display is clear, whether the battery power is discharged, whether all components are complete, and whether its working performance is good;

步骤二、 让患者的一只脚站在该装置的脚踏板上,测试人员指导患者进行足跟抬起练习,Step 2. Let the patient stand on the foot pedal of the device with one foot, and the tester instructs the patient to perform heel lift exercises.

步骤三、长按启停开关,启动本装置;Step 3. Long press the start-stop switch to start the device;

步骤四、通过时间增减按钮中增加按钮增加测试所需的时间;Step 4. Increase the time required for the test through the increase button in the time increase and decrease buttons;

步骤五、待患者足跟抬起稳定后,启动测试开关,光电感应装置对有效的踮脚次数,并将该信息传送至控制板中控制模块;控制模块根据内部的编程程序进行运算,获得最终的有效次数、等级判断信息,并在控制信息在显示屏上进行显示;Step 5. After the patient's heel is lifted and stabilized, start the test switch, and the photoelectric sensor will check the effective number of tiptoes, and send the information to the control module in the control panel; the control module performs calculations according to the internal programming program to obtain the final result. Effective times, grade judgment information, and display the control information on the display;

与现有技术相比,采用上述方案,本发明的有益效果是:本发明能够较准确地为患者的下肢灵活度进行等级判断,能大幅度提高本项目测定的下肢灵活度的精确度,从而提高UPDRS中运动功能部分的分数测定的精度与可靠性;不仅能系统且主动地对具有帕金森病患者的下肢灵活度进行准确的测定,而且能准确地为后续分析提供可靠依据;同时,由于提供了带有有效足跟抬高次数的显示屏,可以精密地给出设定时间内足跟抬高的有效次数;Compared with the prior art, adopting the above scheme, the beneficial effect of the present invention is that the present invention can more accurately judge the grade of the flexibility of the patient's lower limbs, and can greatly improve the accuracy of the flexibility of the lower limbs measured by this project, thereby Improve the accuracy and reliability of the score measurement of the motor function part in UPDRS; not only can systematically and actively measure the flexibility of the lower limbs of patients with Parkinson's disease, but also accurately provide a reliable basis for subsequent analysis; at the same time, due to Provides a display screen with the number of effective heel lifts, which can precisely give the effective number of heel lifts within the set time;

另外,本发明整体采用较硬的塑料材料制成,价格低廉,工艺简单,可以轻便地携带;利于不同实验室研究者测试UPDRS第三部分第26项目的方法、过程与结果的统一,利于对实验的操作过程和结果进行对比分析。In addition, the present invention is made of relatively hard plastic material as a whole, which is cheap, simple in process, and can be carried lightly; it is beneficial to the unification of methods, processes and results of testing the 26th item of UPDRS Part III by researchers in different laboratories, and is beneficial to the The operation process and results of the experiment were compared and analyzed.

附图说明Description of drawings

图1是本发明的结构示意图;Fig. 1 is a structural representation of the present invention;

图2是图1所示的显示屏的结构示意图;Fig. 2 is a structural schematic diagram of the display screen shown in Fig. 1;

图3是图1所示的显示屏与踏脚板连接的结构示意图;Fig. 3 is a structural schematic diagram of the connection between the display screen shown in Fig. 1 and the footboard;

图4是图1所示报警装置结构示意图;Fig. 4 is a structural schematic diagram of the alarm device shown in Fig. 1;

图5是本发明的测试患者脚放置的结构示意图;Fig. 5 is the structural representation of test patient's foot placement of the present invention;

图6是本发明的测试患者脚踮起的结构示意图;Fig. 6 is the structural representation of test patient's pin tiptoe of the present invention;

图7是本发明的控制板结构示意图;Fig. 7 is a schematic structural view of the control board of the present invention;

其中,1.红外线发射器;2.红外线接收器;3.踏脚板;4.时间控制秒表;5.报警单元;6.显示屏;7.启停按钮;8.测试开关; 9.踏板;10、固定板;11.支撑板;12.电池装置;13、减少按钮;14、增加按钮;15、卡槽 。Among them, 1. Infrared transmitter; 2. Infrared receiver; 3. Pedal; 4. Time control stopwatch; 5. Alarm unit; 6. Display; 7. Start and stop button; 8. Test switch; 10. Fixed plate; 11. Support plate; 12. Battery device; 13. Decrease button; 14. Increase button; 15. Card slot.

具体实施方式Detailed ways

下面结合附图和实施例对本发明进一步说明。The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

如图1--图4所示,一种用于帕金森病患者手指捏合能力的测量装置,包括控制板、脚踏垫3、光电感应装置、时间控制秒表4、显示屏6、电池装置12、时间增减按钮、测试开关8及启停按钮7;所述控制板设置在脚踏垫3的内部,用于实现装置各种操作的控制功能;所述光电感应装置设置在脚踏垫3上,且位于前端设置,与脚踏垫3内部的控制板电连接,用于判定测试者的足跟抬起高度是否达到6cm;所述时间控制秒表4设置在显示屏6的上端,用于控制测试时程控制,并发出测试终止讯息;所述显示屏6设置在脚踏垫3的尾部上端,与控制板电连接,用于显示评级级数、计量次数、计量时间;所述时间增减按钮设置在显示屏6的左侧,分别与控制板、显示屏6点连接;用于设定测试时间的长短;所述电池装置12设置在显示屏6的左侧,且靠近时间增减按钮的尾端,用于给整个装置供电;所述启动按钮设置在显示屏6的右侧,分别控制板、显示屏6连接,用于启动整个装置;所述测试按钮设置在显示屏6的右侧,且靠近脚踏垫3的尾端,用于控制下肢测试的启停;As shown in Figures 1 to 4, a measuring device for the kneading ability of the fingers of patients with Parkinson's disease includes a control panel, a foot pad 3, a photoelectric sensor device, a time-controlled stopwatch 4, a display screen 6, and a battery device 12 , time increase and decrease buttons, test switch 8 and start-stop button 7; the control board is arranged on the inside of the pedal pad 3, and is used to realize the control functions of various operations of the device; the photoelectric sensing device is arranged on the pedal pad 3 and located at the front end, electrically connected to the control board inside the foot pad 3, used to determine whether the tester’s heel lift height reaches 6cm; the time control stopwatch 4 is arranged on the upper end of the display screen 6, for Control the test schedule control, and send a test termination message; the display screen 6 is arranged on the upper end of the tail of the foot pad 3, and is electrically connected to the control panel for displaying the rating series, the number of times of measurement, and the measurement time; the time increase The minus button is arranged on the left side of the display screen 6, and is connected with the control board and the display screen at 6 points respectively; it is used to set the length of the test time; the battery device 12 is arranged on the left side of the display screen 6, and is close to the time increase The tail end of the button is used to supply power to the whole device; the start button is arranged on the right side of the display screen 6, and the control panel and the display screen 6 are connected respectively for starting the whole device; the test button is arranged on the display screen 6 The right side, and close to the tail end of the foot pad 3, is used to control the start and stop of the lower limb test;

所述踏脚板3包括踏板9及支撑板11;所述踏板9设置在支撑板11上,与支撑板11插接固定;The tread plate 3 includes a pedal 9 and a support plate 11; the pedal 9 is arranged on the support plate 11, and is plugged and fixed with the support plate 11;

所述踏板9的边缘处设有固定板10,该固定板10使踏板9周边形成凹槽;所述支撑板11嵌入该固定板10形成的凹槽内;The edge of the pedal 9 is provided with a fixed plate 10, and the fixed plate 10 forms a groove around the pedal 9; the support plate 11 is embedded in the groove formed by the fixed plate 10;

优选地,所述踏板9为塑料踏板,采用质地较硬的塑料材质制成;其长度为40cm、宽度为20cm、厚度为0.5cm;Preferably, the pedal 9 is a plastic pedal, made of hard plastic material; its length is 40cm, width is 20cm, and thickness is 0.5cm;

所述固定板10为塑料固定板,采用于踏板9同材质的塑料材质制成,其长度为10cm、厚度为2cm;高度为6.5cm;The fixed plate 10 is a plastic fixed plate, which is made of the same plastic material as the pedal 9, and has a length of 10 cm and a thickness of 2 cm; a height of 6.5 cm;

所述支撑板11为橡胶支撑板;支撑板11采用天然橡胶或其他耐磨橡胶材料制成;支撑板11紧贴地面,防止患者在测试过程中脚步用力导致装置滑动,避免测试结果不准确;The support plate 11 is a rubber support plate; the support plate 11 is made of natural rubber or other wear-resistant rubber materials; the support plate 11 is close to the ground to prevent the device from sliding due to the patient's footsteps during the test, and to avoid inaccurate test results;

所述时间增减按钮包括增加按钮14及减少按钮13;所述增加按钮14用“+”表示,;所述减少按钮13用“-”表示;通过增加按钮14、减少按钮13两种按钮,计量较长时间内的有效踮脚次数;时间设定最长为60秒;最短为0秒;The time increase and decrease buttons include an increase button 14 and a decrease button 13; the increase button 14 is represented by "+"; the decrease button 13 is represented by a "-"; through the increase button 14 and the decrease button 13 two kinds of buttons, Measure the number of effective tiptoes in a long period of time; the longest time setting is 60 seconds; the shortest is 0 seconds;

所述光电感应开关为一对对射式红外线光电开关;其中一个为红外线发射器1;另一个为红外线接收器2;所述光电感应开关为方形开关,所述开关外壳采用塑料外壳;光电感应开关设置在塑料外壳内,塑料外壳上设有一个孔,便于红外线的对射;所述光电感应开关距离踏脚板3的距离为6cm,距离塑料外壳顶部的距离为0.5cm;The photoelectric sensor switch is a pair of through-beam infrared photoelectric switches; one of them is an infrared transmitter 1; the other is an infrared receiver 2; the photoelectric sensor switch is a square switch, and the switch shell adopts a plastic shell; the photoelectric sensor The switch is arranged in the plastic shell, and the plastic shell is provided with a hole, which is convenient for infrared radiation; the distance between the photoelectric sensor switch and the pedal 3 is 6cm, and the distance from the top of the plastic shell is 0.5cm;

优选地,在一对对射的红外线发射器1与红外线接收器2之间的踏脚板3上设有一个黑色的圆点,防止患者测试初始过程中脚后跟放置位置偏离过大,避免导致测试结果不标准;Preferably, a black dot is arranged on the footboard 3 between a pair of opposing infrared transmitters 1 and infrared receivers 2, so as to prevent the position of the patient's heel from being too far from the position during the initial test, and avoid causing test results Not standard;

所述时间控制秒表4为具有编程程序的秒表,实现对患者测试的时间的精确限定;所述时间控制秒表4内设有报警单元5,用于发出测量终止报警信号,终止测量,便于更清晰地给予测试者项目测试结束的信息、利于准确地终止测试;The time control stopwatch 4 is a stopwatch with a programming program, which realizes the precise limitation of the patient's test time; the time control stopwatch 4 is provided with an alarm unit 5, which is used to send a measurement termination alarm signal to terminate the measurement, so as to facilitate clearer Give the tester the information that the project test is over, which is conducive to accurately terminating the test;

优选地,所述显示屏6为电子显示屏,其材质为塑料,长度为1cm,宽度为1cm;显示屏6是数字式的电子显示屏,类似于电子血压计显示屏,可准确地显示出有效踮脚次数、分级分数及所计的秒数;显示屏6为可拆卸更换的显示屏,所述指身装置上设有卡槽15,所述显示屏6可直接卡入该卡槽15内,便于显示屏6的更换;显示屏6数字化显示最后评级级数、计量的次数,便于详细记录、利于后续的多层面深入分析;Preferably, the display screen 6 is an electronic display screen made of plastic, with a length of 1 cm and a width of 1 cm; the display screen 6 is a digital electronic display screen, similar to the display screen of an electronic blood pressure monitor, which can accurately display Effective tiptoe times, graded scores and counted seconds; the display screen 6 is a detachable and replaceable display screen, and the finger body device is provided with a card slot 15, and the display screen 6 can be directly snapped into the card slot 15 , to facilitate the replacement of the display screen 6; the display screen 6 digitally displays the final rating series and the number of measurements, which is convenient for detailed records and subsequent multi-level in-depth analysis;

优选地,所述测试开关8为触碰式按钮开关,根据需要选择启动测试或终止测试;Preferably, the test switch 8 is a touch button switch, which can be selected to start the test or terminate the test as required;

优选地,所述电池装置12为可拆卸式装置,便于电池的安装、拆卸及更换;Preferably, the battery device 12 is a detachable device, which is convenient for installation, removal and replacement of the battery;

如图7所示,所述控制板包括控制模块、显示模块、开关模块、电源模块、时间设定模块、光电感应控制模块及时间控制模块;所述开关模块、显示模块、电源模块、时间设定模块、光电感应控制模块及时间控制模块均为控制模块电连接;所述开关模块分别与启停按钮7、测试开关8电连接;所述显示模块与显示屏6电连接;所述时间设定模块与时间增减按钮连接,实现时间增加或减少的设定;所述电源模块与电池专职电连接,用于给测量装置提供电源;所述光电感应控制模块与光电感应装置电连接,控制两个光电感应装置进行光源相互对射、感应;所述时间控制模块与时间控制秒表4电连接,用于控制时间秒表时间的设定及控制;As shown in Figure 7, the control board includes a control module, a display module, a switch module, a power module, a time setting module, a photoelectric induction control module and a time control module; the switch module, the display module, the power module, the time setting The fixed module, the photoelectric induction control module and the time control module are all electrically connected to the control module; the switch module is electrically connected to the start-stop button 7 and the test switch 8 respectively; the display module is electrically connected to the display screen 6; the time setting The fixed module is connected with the time increase or decrease button to realize the setting of time increase or decrease; the power supply module is electrically connected with the battery to provide power for the measuring device; the photoelectric sensor control module is electrically connected with the photoelectric sensor device to control Two photoelectric sensing devices carry out light source mutual shooting and induction; the time control module is electrically connected with the time control stopwatch 4, and is used to control the setting and control of the time stopwatch time;

所述控制模块为可写入控制程序的中央处理器;经“中央处理器”所获得的最终结果输入显示屏显示出来;例如:患者15秒内做了8次抬脚运动,红外线接收器总共接收次数为8次。输出:8/3,分级/次数,00:15(秒),表示患者15秒内做了8次抬脚运动,记为分级中的3级,也记为3分。The control module is a central processing unit that can be written into the control program; the final result obtained by the "central processing unit" is displayed on the display screen; for example: the patient has raised his feet 8 times within 15 seconds, and the infrared receiver has a total of The number of receptions is 8 times. Output: 8/3, grading/times, 00:15 (seconds), which means that the patient did 8 leg lifts within 15 seconds, which is recorded as grade 3 in the grading, and is also recorded as 3 points.

利用上述装置进行下肢灵活度的测量方法,具体步骤如下:Using the above device to measure the flexibility of the lower limbs, the specific steps are as follows:

步骤一:测量前检查,检测测量装置运行是否正常;显示屏6的显示是否清晰,电池的电量是否冲出,各部件是否齐全、其工作性能是否良好;Step 1: Check before measurement to check whether the measuring device is operating normally; whether the display on the display screen 6 is clear, whether the battery power is discharged, whether all components are complete, and whether their working performance is good;

步骤二、 让患者的一只脚站在该装置的脚踏板上,测试人员指导患者进行足跟抬起练习,Step 2. Let the patient stand on the foot pedal of the device with one foot, and the tester instructs the patient to perform heel lift exercises.

步骤三、长按启停开关,启动本装置;Step 3. Long press the start-stop switch to start the device;

步骤四、通过时间增减按钮中增加按钮增加测试所需的时间;Step 4. Increase the time required for the test through the increase button in the time increase and decrease buttons;

步骤五、待患者足跟抬起稳定后,启动测试开关8,光电感应装置对有效的踮脚次数,并将该信息传送至控制板中控制模块;控制模块根据内部的编程程序进行运算,获得最终的有效次数、等级判断信息,并在控制信息在显示屏6上进行显示;Step 5. After the patient's heel is lifted and stabilized, start the test switch 8, and the photoelectric sensing device will check the effective number of tiptoes, and send the information to the control module in the control panel; the control module performs calculations according to the internal programming program to obtain the final The effective number of times, the level judgment information, and the control information is displayed on the display screen 6;

更具体,本实施例以15秒时间测试为例子:More specifically, this embodiment takes the 15-second time test as an example:

步骤一、在利用本发明进行测试前,需要按照需求对UPDRS中第26项目进行量化设定,不同的实验可以根据不同的测试需求进行量化条件的设定;Step 1. Before using the present invention to test, it is necessary to quantify the 26th item in the UPDRS according to the requirements, and different experiments can be quantified according to different test requirements;

在15秒测试时间内的量化方式为:The quantification method within the 15-second test time is:

0=正常(X≧20次/15秒)0=Normal (X≧20 times/15 seconds)

1=动作轻度减慢或幅度轻度变小(20次/15秒>X≧15次/15秒)1=Slightly slowed down or slightly reduced range of movements (20 times/15 seconds > X≧15 times/15 seconds)

2=中度损害(15次/15秒>X≧10次/15秒)2=moderate damage (15 times/15 seconds > X≧10 times/15 seconds)

3=严重损害(10次/15秒>X≧5次/15秒)3=Serious damage (10 times/15 seconds > X≧5 times/15 seconds)

4=几乎不能完成测试(5次/15秒>X≧0次/15秒)4=The test can hardly be completed (5 times/15 seconds > X≧0 times/15 seconds)

步骤二、向控制板的中央处理器中输入设定程序,具体程序设定如下:Step 2. Input the setting program into the central processing unit of the control panel. The specific program setting is as follows:

output:output:

frequency, grage, t:显示结果frequency, grage, t: display results

method:method:

(1)     初始化时间t和计数器值frequency;(1) Initialization time t and counter value frequency;

(2)     for 每一次运动{(2)for each movement {

       (3)          if t > 15 then(3)if t > 15then

       (4)                 break;(4) break;

       (5)          end if(5)end if

       (6)          if 抬脚高度 > 6 then(6)if foot lift height > 6then

       (7)                 frequency++;       (7)              frequency++;

       (8)          end if(8)end if

       (9)end for(9)end for

       (10)if frequency >= 20 then(10)if frequency >= 20then

       (11)        grade = 0;(11) grade = 0;

       (12)end if(12)end if

       (13)iffrequency >= 15 && frequency <= 19 then(13)if frequency >= 15 && frequency <= 19then

       (14)        grade = 1;(14) grade = 1;

       (15)end if(15)end if

       (16)iffrequency >= 10 && frequency <= 14 then(16)if frequency >= 10 && frequency <= 14then

       (17)        grade = 2;(17) grade = 2;

       (18)end if(18)end if

       (19)if frequency >= 5 && frequency <= 9 then(19)if frequency >= 5 && frequency <= 9then

       (20)        grade = 3;(20) grade = 3;

       (21)end if(21)end if

       (22)if frequency >= 0 && frequency <= 4 then(22)if frequency >= 0 && frequency <= 4then

       (23)        grade = 4;(23) grade = 4;

       (24)end if(24)end if

       (25) printf("%d / %d\n", grade, frequency);(25) printf("%d / %d\n", grade, frequency);

(26) printf("分级 / 次数\n");(26) printf("grading / times\n");

       (27) printf("00:0%d(秒)\n", t);(27) printf("00:0%d(seconds)\n", t);

步骤三、检测本发明装置的运行是否正常,对射式红外线光电开关是否正常、显示屏6的显示是否清晰,电池电量是否充足、各部件是否齐全;并检查背部各部件是否齐全;Step 3: Check whether the operation of the device of the present invention is normal, whether the through-beam infrared photoelectric switch is normal, whether the display of the display screen 6 is clear, whether the battery power is sufficient, and whether each component is complete; and check whether each component on the back is complete;

这个步骤通常要在进行测量前进行,具体的做法如下:取出本发明产品,首先检查测量装置上的各部件是否齐全;然后按下启停开关7,启动本装置;然后,按动增加按钮14,设置所需的时间,若不小心时间设置的太多,可通过减少按钮13进行时间下调,同时查看显示屏6上所显示的数字是否清晰;若不清晰,分析不清晰的原因,若分析结果为显示屏6老化导致数字显示不清晰,则进行显示屏6的更换;若分析结果为电池电量不足导致的数字显示不清晰,则进行电池的更换;待检查合格后,长按启停开关7,即可将测试装置关闭,进入下一步的实际测试;This step will usually be carried out before the measurement, and the specific method is as follows: take out the product of the present invention, first check whether each part on the measuring device is complete; then press the start-stop switch 7 to start the device; then, press the increase button 14 , to set the required time, if you accidentally set too much time, you can use the decrease button 13 to adjust the time down, and at the same time check whether the number displayed on the display screen 6 is clear; if it is not clear, analyze the reason for the unclear The result is that the digital display is not clear due to the aging of the display screen 6, then replace the display screen 6; if the analysis result is that the digital display is not clear due to insufficient battery power, then replace the battery; after the inspection is qualified, press and hold the start-stop switch 7. You can close the test device and enter the next step of the actual test;

检测对射式红外线光电开关是否运行正常,主要方法如下:1、将一物体置于红外线发射装置1和红外线接收装置2之间,观察红外线是否中断,如图5所示;同时观察显示屏6显示是否为0;2、将物体抬高至6cm,观察红外线的状态,同时显示屏6显示是否为1,如图6所示;若两步观察显示正常,则表示红外线光电开关工作正常;若不是,则需检查是否是某一侧的光电开关出问题;To detect whether the through-beam infrared photoelectric switch is operating normally, the main method is as follows: 1. Put an object between the infrared emitting device 1 and the infrared receiving device 2, and observe whether the infrared rays are interrupted, as shown in Figure 5; at the same time, observe the display screen 6 Whether the display is 0; 2. Raise the object to 6cm, observe the state of the infrared ray, and at the same time the display 6 displays whether it is 1, as shown in Figure 6; if the two-step observation shows normal, it means that the infrared photoelectric switch is working normally; if If not, you need to check whether there is a problem with the photoelectric switch on one side;

优选地,当无遮挡物时,红外线接收器2接收到红外线发射器1发出的红外线,其触点动作;当有物体挡住时,红外线接收器2便接收不到红外线发射器1发出的红外线,其触点复位;即当患者快速反复踮起足跟使腿抬起,足跟抬高至少6cm时,红外线传导完整,红外线接收器可以接收到发射器发出的红外线信号,通过只要抬脚高度>6cm就累加一次,再以有效次数的形式传送给“中央处理器”,由中央处理器根据以下编程进行运算计数;在15秒内,红外线接收器接受一次红外线算一次有效次数;Preferably, when there is no obstruction, the infrared receiver 2 receives the infrared rays sent by the infrared transmitter 1, and its contact action; when an object is blocked, the infrared receiver 2 cannot receive the infrared rays sent by the infrared transmitter 1, Its contacts are reset; that is, when the patient quickly and repeatedly lifts the heel to lift the leg, and the heel is raised by at least 6cm, the infrared ray conduction is complete, and the infrared receiver can receive the infrared signal sent by the transmitter. 6cm will be accumulated once, and then sent to the "central processing unit" in the form of effective times, and the central processor will perform calculation and counting according to the following programming; within 15 seconds, the infrared receiver receives an infrared ray and counts an effective number of times;

显示屏6的更换只需将原有的显示屏从卡槽15中取下,并断开显示屏6与显示模块之间的连接,将新的显示屏与显示模块进行连接后,将新的显示屏卡入卡槽15即可;The replacement of display screen 6 only needs to take off original display screen from card slot 15, and disconnect the connection between display screen 6 and display module, after new display screen and display module are connected, new The display screen can be snapped into the card slot 15;

电池的更换过程与目前市面上的录音机、玩具汽车类似,在此不再累述;The battery replacement process is similar to that of tape recorders and toy cars currently on the market, so I won’t repeat it here;

步骤四、长按启停按钮7,启动本发明装置,按动增加按钮14,将时间增加到测试所需的时间,即15s;Step 4, press the start-stop button 7 for a long time, start the device of the present invention, press the increase button 14, and increase the time to the time required for the test, i.e. 15s;

若增加的时间超过15s,则按动减少按钮13,将时间减少到15s;If the increased time exceeds 15s, then press the decrease button 13 to reduce the time to 15s;

步骤五、如图5所示,测试人员先在地面上指导测试患者进行踮脚动作,待测试者踮脚动作稳定后,测试人员指导患者将脚放置在踏脚板3上,脚跟中心至于黑色圆点上,前脚掌自然放置,然后在踏脚板3上,指导患者进行踮脚,并使足跟部抬高6cm,按下测试开关8,开始进行测试;Step 5, as shown in Figure 5, the tester first guides the test patient to perform tiptoe movements on the ground. After the tester’s tiptoe movement is stable, the tester instructs the patient to place the foot on the footboard 3, with the center of the heel on the black dot , the forefoot is placed naturally, and then on the footboard 3, instruct the patient to tiptoe, and raise the heel by 6cm, press the test switch 8, and start the test;

步骤六、红外线接收装置2接收红外线发射装置发射的红外线光;并将该光信号转换成电信号,传送至控制板中的控制模块,Step 6, the infrared receiving device 2 receives the infrared light emitted by the infrared emitting device; and converts the optical signal into an electrical signal, and transmits it to the control module in the control panel,

注,足跟抬高6cm后成功接收一次红外线光信号,此时计为一次有效的足跟抬高动作;Note, if the heel is raised by 6cm and the infrared light signal is successfully received once, it is counted as a valid heel raising action at this time;

步骤七、控制模块根据内部中央处理器中的编程程序进行运算,得到最终的有效次数信息,累计计数,待到达15s测试时间时,时间控制秒表4上的报警单元5发出“滴滴”的报警声,表示测试时间已到,提醒测试人员关闭测试开关5;控制模块进行等级级数的判断;并将结果显示在显示屏6上;Step 7, the control module performs calculations according to the programming program in the internal central processing unit, and obtains the final effective number of times information, and counts them cumulatively. When the 15s test time is reached, the alarm unit 5 on the time control stopwatch 4 sends out a "didi" alarm sound, indicating that the test time has arrived, and the tester is reminded to close the test switch 5; the control module carries out the judgment of the grade series; and the result is displayed on the display screen 6;

本发明在于提供一种简易的、标准的、精确的,即利用简易编程控制时程、利用简易编程识别并累计踮起足跟有效次数,避免在短暂时间里计数不准、评分不准的结果,从而大大提高本项目测试结果的精确度和可靠度;通过此UPDRS第三部分中第26项目配套装置,给予患者简单的教习之后,将开始准确计量患者有效踮起足跟次数,从而给予后续下肢灵活度的评分、UPDRS第三部分提供可靠的基础数据,以利于UPDRS第三部分后续的相关分析,从而可将PD患者运动功能情况与实验的一些其他方面的相关性得到准确量化,比如在功能磁共振检查中,可将PD患者以数值方式量化的脑区受刺激的激活位置与程度与下肢灵活度作相关分析,得出不同脑区刺激位置、程度是否与下肢灵活度的损害程度相关。深入探索,可能掌握有下肢灵活度损害的患者的具体的有相关的脑区损害区域以及由该脑区激活程度来推导反映出的手指下降程度;下肢灵活度损害为患者运动功能损害的项目之一,以期根据这些特定的脑区损害与其他疾病相鉴别,准确地识别帕金森病,为帕金森病的早期识别、早期治疗与治疗检测提供有力的证据;The present invention is to provide a simple, standard and accurate method, that is, to use simple programming to control the time course, to use simple programming to identify and accumulate the effective times of standing on tiptoe, and to avoid inaccurate counting and inaccurate scoring results in a short period of time. , so as to greatly improve the accuracy and reliability of the test results of this project; through the supporting device of item 26 in the third part of the UPDRS, after giving simple teaching to the patient, the patient will start to accurately measure the number of times the patient can lift the heel effectively, so as to give follow-up The lower limb flexibility score and the third part of the UPDRS provide reliable basic data to facilitate the subsequent correlation analysis of the third part of the UPDRS, so that the correlation between the motor function of PD patients and some other aspects of the experiment can be accurately quantified, such as in In functional magnetic resonance examination, the numerically quantified activation position and degree of brain region stimulation in PD patients can be correlated with lower limb flexibility, and it can be concluded whether the stimulation position and degree of different brain regions are related to the degree of damage to lower limb flexibility . Through in-depth exploration, it is possible to grasp the specific and related brain area damage in patients with lower limb flexibility impairment and the degree of finger descent reflected by the activation of this brain region; lower limb flexibility impairment is one of the items of motor function impairment in patients First, in order to distinguish Parkinson's disease from other diseases based on these specific brain damages, and provide strong evidence for early identification, early treatment and treatment detection of Parkinson's disease;

通过本发明可以对帕金森病人踮脚运动功能(快速反复踮起足跟使腿抬起,足跟抬高至少6cm)做以下研究:1、根据下肢踮脚运动功能与一些诊断方法做相关性分析研究诊断方法的可行性;例如:下肢踮脚运动功能损害程度与帕金森病Hoehn-Yahr(修正)分级量表分级的相关性,下肢踮脚运动功能损坏程度与下肢踮脚运动事件相关性功能磁共振研究所激活脑区的相关性,下肢踮脚运动功能损坏程度与脑电图受损程度之间的相关性,下肢踮脚运动功能损坏程度与经颅磁刺激后显示脑部损坏程度之间的相关性;2、监测治疗后的功能恢复情况;下肢踮脚运动功能恢复程度与各种药物治疗、手术治疗细胞治疗、基因治疗及使用其他新治疗方法后功能恢复的相关性;Through the present invention, the following research can be done on the tiptoe motor function of Parkinson's patients (rapidly and repeatedly tiptoe the heel to lift the leg, and the heel is raised by at least 6cm): 1. Do correlation analysis and research according to the lower limb tiptoe motor function and some diagnostic methods Feasibility of diagnostic methods; for example: Correlation between the degree of lower extremity tiptoe motor impairment and Parkinson's disease Hoehn-Yahr (modified) grading scale, the correlation between lower extremity tiptoe motor impairment and lower extremity tiptoe motor events Functional Magnetic Resonance Institute The correlation of activated brain regions, the correlation between the damage degree of tiptoe motor function of lower limbs and the degree of EEG damage, the correlation between the degree of motor function damage of lower limb tiptoe movement and the degree of brain damage after transcranial magnetic stimulation;2 , Monitoring the recovery of function after treatment; the correlation between the recovery of tiptoe motor function of the lower limbs and the recovery of function after various drug treatments, surgical treatment, cell therapy, gene therapy and other new treatment methods;

根据本发明的下肢灵活度评级装置,由于能通过任意设定时程、短时间内有效地捕捉患者的有效足跟抬高次数,因此能大大提高对国际用统一帕金森病评定量表(Unified Parkinson’s Disease Rating Scal,UPDRS)第三部分第26项目的测试精准度;整套具有精确时间设置、统一标准化定位有效足跟抬高运动的装置,能准确给予下肢灵活度评分,也能详细给予患者特定时间内的有效足跟抬高运动次数,所以能大幅度提高下肢灵活度测试结果的精度和可靠性;According to the lower limb flexibility rating device of the present invention, since the effective heel raising times of the patient can be captured effectively in a short period of time by arbitrarily setting the time course, it can greatly improve the international use of the unified Parkinson's disease rating scale (Unified Parkinson's Disease Rating Scale). Parkinson's Disease Rating Scal, UPDRS) test accuracy of the 26th item in the third part; the whole set has precise time setting, unified standardized positioning and effective heel raising movement device, can accurately give lower limb flexibility score, and can also give patients specific The number of effective heel raising movements within a certain period of time can greatly improve the accuracy and reliability of the lower limb flexibility test results;

本发明能够较准确地为患者的下肢灵活度进行等级判断,能大幅度提高本项目测定的下肢灵活度的精确度,从而提高UPDRS中运动功能部分的分数测定的精度与可靠性;不仅能系统且主动地对具有帕金森病患者的下肢灵活度进行准确的测定,而且能准确地为后续分析提供可靠依据;同时,由于提供了带有有效足跟抬高次数的显示屏,可以精密地给出设定时间内足跟抬高的有效次数;The present invention can more accurately judge the degree of flexibility of the patient's lower limbs, and can greatly improve the accuracy of the lower limb flexibility measured in this project, thereby improving the accuracy and reliability of the score measurement of the motor function part in the UPDRS; not only can the system It can actively and accurately measure the flexibility of the lower limbs of patients with Parkinson's disease, and can accurately provide a reliable basis for subsequent analysis; at the same time, because it provides a display screen with effective heel raising times, it can precisely give The effective number of heel lifts within the set time;

另外,本发明整体采用较硬的塑料材料制成,价格低廉,工艺简单,可以轻便地携带;利于不同实验室研究者测试UPDRS第三部分第26项目的方法、过程与结果的统一,利于对实验的操作过程和结果进行对比分析;In addition, the present invention is made of relatively hard plastic material as a whole, which is cheap, simple in process, and can be carried lightly; it is beneficial to the unification of methods, processes and results of testing the 26th item of UPDRS Part III by researchers in different laboratories, and is beneficial to the Comparative analysis of the operation process and results of the experiment;

本发明不局限于上述具体的实施方式,本领域的普通技术人员从上述构思出发,不经过创造性的劳动,所作出的种种变换,均落在本发明的保护范围之内。The present invention is not limited to the above-mentioned specific implementation manners, and various transformations made by those skilled in the art starting from the above-mentioned concept without creative work all fall within the protection scope of the present invention.

Claims (10)

Translated fromChinese
1.一种用于帕金森病患者下肢灵活度的测量装置,包括控制板、脚踏垫、光电感应装置、时间控制秒表、显示屏、电池装置、时间增减按钮、测试开关及启停按钮;其特征在于:1. A measuring device for the flexibility of the lower limbs of patients with Parkinson's disease, including a control panel, a foot pad, a photoelectric sensor device, a time-controlled stopwatch, a display screen, a battery device, time increase and decrease buttons, a test switch and a start-stop button ; characterized by:所述控制板设置在脚踏垫的内部,用于实现装置各种操作的控制功能;The control board is arranged inside the foot pad, and is used to realize the control functions of various operations of the device;所述光电感应装置设置在脚踏垫上,且位于前端设置,与脚踏垫内部的控制板电连接,用于判定测试者的足跟抬起高度是否达到6cm;The photoelectric sensing device is arranged on the foot pad, and is located at the front end, and is electrically connected to the control board inside the foot pad, and is used to determine whether the heel lift height of the tester reaches 6cm;所述时间控制秒表设置在显示屏的上端,用于控制测试时程控制,并发出测试终止讯息;The time control stopwatch is set on the upper end of the display screen, used to control the test schedule control, and send a test termination message;所述显示屏设置在脚踏垫的尾部上端,与控制板电连接,用于显示评级级数、计量次数、计量时间;The display screen is arranged on the upper end of the tail of the foot pad, and is electrically connected to the control panel, and is used to display the rating series, the number of times of measurement, and the time of measurement;所述时间增减按钮设置在显示屏的左侧,分别与控制板、显示屏点连接;用于设定测试时间的长短;The time increase and decrease buttons are arranged on the left side of the display screen, respectively connected to the control panel and the display screen; used to set the length of the test time;所述电池装置设置在显示屏的左侧,且靠近时间增减按钮的尾端,用于给整个装置供电;The battery device is arranged on the left side of the display screen, and is close to the tail end of the time increase and decrease buttons, and is used to supply power to the whole device;所述启动按钮设置在显示屏的右侧,分别控制板、显示屏连接,用于启动整个装置;The start button is arranged on the right side of the display screen, connected to the control board and the display screen respectively, and is used to start the whole device;所述测试按钮设置在显示屏的右侧,且靠近脚踏垫的尾端,用于控制下肢测试的启停。The test button is arranged on the right side of the display screen and near the tail end of the foot pad, and is used to control the start and stop of the lower limb test.2.根据权利要求1所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述控制板包括控制模块、显示模块、开关模块、电源模块、时间设定模块、光电感应控制模块及时间控制模块;所述开关模块、显示模块、电源模块、时间设定模块、光电感应控制模块及时间控制模块均为控制模块电连接;所述开关模块分别与启停按钮、测试开关电连接;所述显示模块与显示屏电连接;所述时间设定模块与时间增减按钮连接,实现时间增加或减少的设定;所述电源模块与电池专职电连接,用于给测量装置提供电源;所述光电感应控制模块与光电感应装置电连接,控制两个光电感应装置进行光源相互对射、感应;所述时间控制模块与时间控制秒表电连接,用于控制时间秒表时间的设定及控制。2. A kind of measuring device for the flexibility of the lower limbs of Parkinson's disease patients according to claim 1, characterized in that: the control board includes a control module, a display module, a switch module, a power supply module, a time setting module, A photoelectric induction control module and a time control module; the switch module, display module, power supply module, time setting module, photoelectric induction control module and time control module are all electrically connected to the control module; the switch module is respectively connected to the start-stop button, The test switch is electrically connected; the display module is electrically connected to the display screen; the time setting module is connected to the time increase or decrease button to realize the setting of time increase or decrease; the power supply module is fully electrically connected to the battery for giving The measuring device provides power; the photoelectric sensor control module is electrically connected to the photoelectric sensor device, and controls the two photoelectric sensor devices to carry out light source mutual shooting and induction; the time control module is electrically connected to the time control stopwatch, and is used to control the time stopwatch time settings and controls.3.根据权利要求2所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述控制模块为可写入控制程序的中央处理器。3 . The device for measuring flexibility of the lower limbs of Parkinson's disease patients according to claim 2 , wherein the control module is a central processing unit that can be written into a control program. 4 .4.根据权利要求1所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述踏脚板包括踏板及支撑板;所述踏板设置在支撑板上,与支撑板插接固定。4. A kind of measuring device for the flexibility of lower limbs of patients with Parkinson's disease according to claim 1, characterized in that: the tread plate comprises a pedal and a support plate; the pedal is arranged on the support plate, and the support plate Plug in and fix.5.根据权利要求4所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述踏板为塑料踏板;其长度为40cm、宽度为20cm、厚度为0.5cm。5. A device for measuring flexibility of the lower limbs of Parkinson's disease patients according to claim 4, characterized in that: the pedal is a plastic pedal; its length is 40cm, width is 20cm, and thickness is 0.5cm.6.根据权利要求4所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述支撑板为橡胶支撑板。6 . The device for measuring flexibility of the lower limbs of Parkinson's disease patients according to claim 4 , wherein the support plate is a rubber support plate. 7 .7.根据权利要求1所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述时间增减按钮包括增加按钮及减少按钮;所述增加按钮用“+”表示;所述减少按钮用“-”表示。7. A device for measuring the flexibility of lower limbs of Parkinson's disease patients according to claim 1, characterized in that: the time increase and decrease buttons include an increase button and a decrease button; the increase button is represented by "+" ; The decrease button is represented by "-".8.根据权利要求1所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述光电感应开关为一对对射式红外线光电开关;其中一个为红外线发射器;另一个为红外线接收器。8. A device for measuring the flexibility of the lower limbs of patients with Parkinson's disease according to claim 1, wherein the photoelectric sensor switch is a pair of through-beam infrared photoelectric switches; one of them is an infrared emitter; The other is an infrared receiver.9.根据权利要求1所述的一种用于帕金森病患者下肢灵活度的测量装置,其特征在于:所述时间控制秒表为具有编程程序的秒表;所述时间控制秒表内设有报警单元,用于发出测量终止报警信号,终止测量。9. A kind of measuring device for the flexibility of the lower limbs of patients with Parkinson's disease according to claim 1, characterized in that: said time control stopwatch is a stopwatch with a programming program; said time control stopwatch is provided with an alarm unit , used to issue a measurement termination alarm signal to terminate the measurement.10.利用如权利要求1所述的装置进行下肢灵活度的测量方法,具体步骤如下:10. utilize device as claimed in claim 1 to carry out the measurement method of lower limb flexibility, concrete steps are as follows:步骤一:测量前检查,检测测量装置运行是否正常;显示屏的显示是否清晰,电池的电量是否冲出,各部件是否齐全、其工作性能是否良好;Step 1: Check before measurement to check whether the measuring device is operating normally; whether the display is clear, whether the battery power is discharged, whether all components are complete, and whether its working performance is good;步骤二、 让患者的一只脚站在该装置的脚踏板上,测试人员指导患者进行足跟抬起练习,Step 2. Let the patient stand on the foot pedal of the device with one foot, and the tester instructs the patient to perform heel lift exercises.步骤三、长按启停开关,启动本装置;Step 3. Long press the start-stop switch to start the device;步骤四、通过时间增减按钮中增加按钮增加测试所需的时间;Step 4. Increase the time required for the test through the increase button in the time increase and decrease buttons;步骤五、待患者足跟抬起稳定后,启动测试开关,光电感应装置对有效的踮脚次数,并将该信息传送至控制板中控制模块;控制模块根据内部的编程程序进行运算,获得最终的有效次数、等级判断信息,并在控制信息在显示屏上进行显示。Step 5. After the patient's heel is lifted and stabilized, start the test switch, and the photoelectric sensor will check the effective number of tiptoes, and send the information to the control module in the control panel; the control module performs calculations according to the internal programming program to obtain the final result. Effective times, grade judgment information, and display the control information on the display screen.
CN201410416108.9A2014-08-222014-08-22Measuring device and measuring method for judgment of lower limb flexibility of parkinsonianPendingCN104207780A (en)

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