A kind of joint nutrient solution that can be used to importTechnical field
The present invention relates to field of medicaments more particularly to a kind of joint nutrient solutions that can be used to import.
Background technique
Osteoarthropathy just has and all over the world from ancient times, and paleontologist is from the dinosaur before 200,000,000 years and the mankind before 500,000 yearsIt has been found that in osseous remains with the presence of osteoarthritis.People to after 60 years old, when internal ammonia sugar only has young 3%, 70 years old when be almostZero, osteoarthropathy is almost inevitable, so, supplementing ammonia sugar as early as possible is the most important thing for preventing and treating osteoarthropathy.
Currently, ammonia sugar is as articular cartilage nutritional agents the most direct, by World Health Organization's public affairs in worldwideThink the specific drug for uniquely capableing of fundamentally rehabilitation osteoarthrosis.It is currently on the market mainly traditional oral ammoniaSugar also generates very big side effect, it will pass through although oral ammonia sugar has certain effect to treatment bone and joint diseases simultaneouslyPeptic digest and intestinal absorption increase stomach burden and liver kidney burden to some extent, especially very big to the damage of kidney；Secondly,Although oral ammonia sugar plays certain relaxation effect to aseptic inflammation, cannot tackle the problem at its root.
Summary of the invention
The purpose of invention: in order to provide the joint nutrient solution that a kind of effect does not damage liver kidney preferably, specific purposes are shown in toolMultiple substantial technological effects of body implementation section.
In order to reach purpose as above, the present invention is adopted the following technical scheme that:
It is a kind of can be used for import joint nutrient solution prescription, which is characterized in that the substance comprising following parts by weight, go from30 parts of sub- water --- 60 parts；Ammonia sugar, 10 parts --- 30 parts；Chondroitin sulfate, 8 parts --- 20 parts；Chinese scholartree reality extract, 2 parts ---10 parts；TypeⅡ Collagen, 5 parts --- 10 parts；Lysozyme, 5 parts --- 15 parts；Amino acid humectant, 5 parts --- 8 parts；It is transparentMatter acid sodium, 0.1 part --- 1 part.
A kind of joint nutrient solution that can be used to import, which is characterized in that grasped the substance of following parts by weight as followsMake, the substance comprising following parts by weight, 30 parts of deionized water --- 60 parts；Ammonia sugar, 10 parts --- 30 parts；Chondroitin sulfate,8 parts --- 20 parts；Chinese scholartree reality extract, 2 parts --- 10 parts；TypeⅡ Collagen, 5 parts --- 10 parts；Lysozyme, 5 parts --- 15Part；Amino acid humectant, 5 parts --- 8 parts；Sodium Hyaluronate, 0.1 part --- 1 part；
Various substances above other than Chinese scholartree reality extract and deionized water are removed into impurity；Each raw material is faced with super respectivelyBoundary fluid CO2 carries out innoxious extraction, and extraction conditions is that raw material is first crushed to 20-60 mesh；Pressure 50MPa-60MPa；EntrainmentAgent: ethyl acetate parts by weight are the 30% of raw material gross weight；Reaction kettle is added in deionized water, 85 DEG C is heated to and keeps the temperature 30 pointsClock, is cooled to 5 DEG C, and raw material needed for being formulated is added, and stirs 30 minutes, constant temperature 72 hours, 500 mesh filterings, impurity elimination, spare.
The further technical solution of the present invention is, also includes the step of being mixed into active material, the active material is mixed into standbyIt in liquid, is added in the aqueous solution of Chinese scholartree reality extract after being stirred under vacuum 1.5 hours, stands 48 hours, discharging；Semi-finished product inspectionIt surveys；Sterile filling；Packaging.
The further technical solution of the present invention is that the active material is biological active ammonia sugar.
Using the present invention of technical solution as above, have the advantages that compared with the existing technology: our company has developed oneKind effectively treatment bone and joint diseases liquid, this liquid by instrument can multiple spot, uniformly, comprehensively, positioning, given layer, quantitativelyGround is delivered directly to active ingredient in the Bones and joints for being badly in need for the treatment of, allows various active composition and nutriment rapidly by Bones and jointsAnd surrounding tissue absorbs, and then promotes Bones and joints metabolism, and the function of the nutriments such as ammonia sugar is performed to maximum utility；ItsSecondary, this liquid fundamentally solves the problems, such as aseptic inflammation, drives away inflammation, effectively treatment Bones and joints；Again, this liquid withoutIt need to take orally, bear stomach and intestine zero, liver kidney is not damaged, and therapeutic process does not have any side effect to human body, fast and effeciently solves painBitterly.
Specific embodiment
The embodiment of the present invention is illustrated below, embodiment is not construed as limiting the invention:
Embodiment one:
The substance of following parts by weight is proceeded as follows, the substance comprising following parts by weight, deionized water 30Part；Ammonia sugar, 10 parts；Chondroitin sulfate, 8 parts；Chinese scholartree reality extract, 2 parts；TypeⅡ Collagen, 5 parts；Lysozyme, 5 parts；Amino acidMoisturizer, 5 parts；Sodium Hyaluronate, 0.1 part；
Various substances above other than Chinese scholartree reality extract and deionized water are removed into impurity；Each raw material is faced with super respectivelyBoundary fluid CO2 carries out innoxious extraction, and extraction conditions is that raw material is first crushed to 20-60 mesh；Pressure 50MPa-60MPa；EntrainmentAgent: ethyl acetate parts by weight are the 30% of raw material gross weight；Reaction kettle is added in deionized water, 85 DEG C is heated to and keeps the temperature 30 pointsClock, is cooled to 5 DEG C, and raw material needed for being formulated is added, and stirs 30 minutes, constant temperature 72 hours, 500 mesh filterings, impurity elimination, spare.
The further technical solution of the present invention is, also includes the step of being mixed into active material, the active ammonia sugar is mixed into standbyIt in liquid, is added in the aqueous solution of Chinese scholartree reality extract after being stirred under vacuum 1.5 hours, stands 48 hours, discharging；Semi-finished product inspectionIt surveys；Sterile filling；Packaging.
Embodiment two:
A kind of joint nutrient solution that can be used to import, which is characterized in that grasped the substance of following parts by weight as followsMake, the substance comprising following parts by weight, 60 parts of deionized water；Ammonia sugar, 30 parts；Chondroitin sulfate, 20 parts；Chinese scholartree reality extract,10 parts；TypeⅡ Collagen, 10 parts；Lysozyme, 15 parts；Amino acid humectant, 8 parts；Sodium Hyaluronate, 1 part；
Various substances above other than Chinese scholartree reality extract and deionized water are removed into impurity；Each raw material is faced with super respectivelyBoundary fluid CO2 carries out innoxious extraction, and extraction conditions is that raw material is first crushed to 20-60 mesh；Pressure 50MPa-60MPa；EntrainmentAgent: ethyl acetate parts by weight are the 30% of raw material gross weight；Reaction kettle is added in deionized water, 85 DEG C is heated to and keeps the temperature 30 pointsClock, is cooled to 5 DEG C, and raw material needed for being formulated is added, and stirs 30 minutes, constant temperature 72 hours, 500 mesh filterings, impurity elimination, spare.
The further technical solution of the present invention is, also includes the step of being mixed into active material, the active material is mixed into standbyIt in liquid, is added in the aqueous solution of Chinese scholartree reality extract after being stirred under vacuum 1.5 hours, stands 48 hours, discharging；Semi-finished product inspectionIt surveys；Sterile filling；Packaging.
It should be noted that the bioactivity ammonia sugar that the present invention only treats osteoarthropathy is example, but not as limitSystem, as long as similar water-soluble material mixing can.
The various appellations occurred in text are the prior art, but a combination thereof is not；
Some basic explanations are done to noun below:
Sodium Hyaluronate (SODIUM HYALURONATE) is the substance extracted from cockscomb；
Amino acid humectant chemical name: trimethylglycine；English name: trimethyl glycine；
Chondroitin sulfate (CS) is to be covalently attached a kind of glycosaminoglycan that proteoglycans is formed on protein.Chondroitin sulfateElement is distributed widely in the extracellular matrix and cell surface of animal tissue, and sugar chain is by alternate glucuronic acid and N- acetyl galaOsamine (also known as N- acetylamino galactosamine) disaccharide unit composition, the silk ammonia of core protein is connected to by one like sugar chain blockOn sour residue.
The full name D- Glucosamine of ammonia sugar belongs to monosaccharide composition, can extract from the ginseng of in crab shrimp shell and red pole, be hydrophilyThe important component of extremely strong proteoglycan.
Chinese scholartree reality extract is also Fructus Sophorae extract, Classification system:Fructus sophorae。
Enclose clinical experiment report:
| Name | Gender | Age | Address | Sick time | Control preceding symptom | With this medicine treatment time | Clinical cure |
| Sun | Female | 76 years old | Xi'an | 2000.5 | Prolapse of lumbar intervertebral disc | 3 months (embodiment one) | Clinical Pain disappears |
| Lee | Male | 82 years old | Wugong County | 1986.3 | Ischiatitis | 3 months (embodiment one) | Clinical Pain disappears |
| Side certain | Male | 70 years old | Nanning City | 1997.11 | Leg retrogression pathological changes | 12 months (embodiment one) | Clinical Pain disappears |
| Liu | Male | 65 years old | Yuanmou of Yunnan Province | 2009.11 | Double-legged spur | 6 months (embodiment one) | Clinical Pain disappears |
| Mr. Wang | Female | 65 years old | Sichuan Yibin | 2003.4 | Rheumatoid arthritis | 12 months (embodiment one) | Clinical Pain disappears |
| Shen | Female | 69 years old | Guangxi Yulin | 2009.5 | Osteoproliferation | 9 months (embodiment one) | Clinical Pain disappears |
| Cui | Male | 57 years old | Chengde | 1994.1 | Knee joint retrogression pathological changes | 5 months (embodiment one) | Clinical Pain disappears |
| Mr. Wang | Male | 52 years old | Tieling | 2011.5 | Waist disc bulging | 4 months (embodiment one) | Clinical Pain disappears |
| High mountain | Male | 45 years old | Heze City, Shandong Province | 2012.3 | Prolapse of lumbar intervertebral disc | 3 months (embodiment one) | Clinical Pain disappears |
| It is pungent certain | Female | 49 years old | Distributions in Liaocheng of Shandong Province | 2011.9 | Cervical spondylosis bone sassafras sound | 8 months (embodiment one) | Clinical Pain disappears |
| Qian | Male | 57 years old | Yinchuan of Ningxia Province | 2004.8 | Prolapse of lumbar intervertebral disc | 6 months (embodiment two) | Clinical Pain disappears |
| Dragon certain | Female | 68 years old | Chengde | 1988.4 | Synovitis | 1 month (embodiment two) | Clinical Pain disappears |
| Ma | Male | 52 years old | Huludao City | 2001.9 | Knee joint rheumatic arthritis | 6 months (embodiment two) | Clinical Pain disappears |
| Cao | Female | 53 years old | Xi'an | 2013.5 | Cervical spondylosis | 2 months (embodiment two) | Clinical Pain disappears |
| Lu | Male | 55 years old | Tieling | 2012.8 | Waist disc bulging | 6 months (embodiment two) | Clinical Pain disappears |
| Mr. Wang | Female | 66 years old | Yingkou City | 1999.3 | Knee joint retrogression pathological changes | 5 months (embodiment two) | Clinical Pain disappears |
| Ma | Male | 56 years old | Baotou | 1989.5 | Prolapse of lumbar intervertebral disc | 3 months (embodiment two) | Clinical Pain disappears |
| Mr. Wang | Male | 73 years old | Heze City | 2012.4 | Rheumatoid arthritis | 12 months (embodiment two) | Clinical Pain disappears |
| Qian | Male | 60 years old | Urumchi | 2009.8 | Cervical spondylosis | 7 months (embodiment two) | Clinical Pain disappears |
| Poplar | Male | 77 years old | Changsha | 1982.1 | Rheumatic arthritis | 12 months (embodiment two) | Clinical Pain disappears |
| Lee | Female | 59 years old | Luoyang City | 2012.3 | Prolapse of lumbar intervertebral disc | 4 months (embodiment two) | Clinical Pain disappears |
| Liu | Female | 67 years old | Xinjiang Urumqi | 2009.5 | Knee joint retrogression pathological changes | 6 months (embodiment two) | Clinical Pain disappears |
| History | Female | 55 years old | Anyang | 2011.6 | Cervical spondylosis | 1 month (embodiment two) | Clinical Pain disappears |
| Cui | Female | 56 years old | Yichang City | 1985.2 | Rheumatic gonitis | 3 months (embodiment two) | Clinical Pain disappears |
| Guo | Male | 55 years old | Wuhan City | 2011.6 | Knee joint endoprosthesis is scorching | 3 months (embodiment two) | Clinical Pain disappears |
| Often certain | Male | 48 years old | Jingmen | 2014.1 | Bursal synovitis | 7 months (embodiment two) | Clinical Pain disappears |
| Zhao | Male | 66 years old | Hangzhou | 2011.7 | Protrusion of lumber intervertebral disc | 3 months (embodiment two) | Clinical Pain disappears |
| Mr. Wang | Female | 49 years old | Yingkou City | 2013.9 | Cervical spondylosis | 3 months (embodiment two) | Clinical Pain disappears |
| Week certain | Female | 46 years old | Chiping County | 2014.3 | Articulations digitorum manus tenosynovitis | 2 months (embodiment two) | Clinical Pain disappears |
| Fourth | Male | 42 years old | Yinchuan | 2012.3 | Prolapse of lumbar intervertebral disc | 7 months (embodiment two) | Clinical Pain disappears |
| Shi | Male | 56 years old | Xinjiang Urumqi | 2009.12 | Tennis elbow | 2 months (embodiment two) | Clinical Pain disappears |
| Gold certain | Female | 73 years old | Weinan City | 2000.5 | Leg retrogression pathological changes | 4 months (embodiment two) | Clinical Pain disappears |
| Still certain | Male | 49 years old | Tieling | 2011.3 | Prolapse of lumbar intervertebral disc | 8 months (embodiment two) | Clinical Pain disappears |
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of this fieldPersonnel should be recognized that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this hairsBright principle, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these variationsIt is both fallen in claimed range with improving.