In vitro fertilization and embryo transfer information checking methodTechnical field
The present invention relates to a kind of in vitro fertilization and embryo transfer information checking method, belong to biotechnology and Medical Devices technical field.
Background technology
In test-tube baby's therapeutic process of transgenic animals, cloned animal and the mankind, more and more use technology in vitro fertilization and embryo transfer technology.Carry out in vitro the artificial combination of sperm and ovum, form embryonated egg, by vitro culture, development of fertilized ova is become to embryo.Utilize embryo transfer technology, embryo transfer is gone back to parent uterus and then obtained gestation.Yet, in the prior art, the combination of essence ovum and embryo transfer are all to check by artificial mode, because incubation time is long, link is more, there will be unavoidably and checks mistake, the smart ovum leading to errors in conjunction with or wrong embryo transfer is gone back to parent uterus, once because this mistake is not easy to be discovered, will cause the inaccurate of result of study.Particularly, in mankind test-tube baby therapeutic process, if there is similar mistake, will cause serious ethics problem and medical tangle.
Summary of the invention
The present invention has overcome the deficiencies in the prior art, a kind of in vitro fertilization and embryo transfer information checking method is provided, sperm can effectively be checked in the situation that not needing manual intervention whether consistent with ovum identity information, whether embryo is consistent with parent identity information, thereby guarantees that smart ovum combination is correct and embryo transfer is correct.
In order to achieve the above object, the technical solution used in the present invention is:
A1, the corresponding identity information of sperm, ovum, embryo and parent is stored in database;
A2, by radio-frequency technique, identify current sperm, ovum, embryo's double dish and the relevant identity information of parent identification ring of being loaded with;
A3, search database, whether the identity information that comparison obtains mates with database, and if so, pairing is correctly; If not, match mistake.
As a further improvement on the present invention, before described A2 step, also comprise: for each double dish and parent identification ring that is loaded with sperm, ovum, embryo arranges a RFID label of indicating identity information.
As a further improvement on the present invention, described A2 step specifically also comprises: before smart ovum binding operation, distinguish the RFID label on the double dish that is loaded with sperm, ovum, obtain both identity informations.Before embryo transfer operation, distinguish the RFID label on the double dish that is loaded with embryo, distinguish the entrained identification ring RFID label of parent, obtain both identity informations.
As a further improvement on the present invention, described A3 step specifically also comprises: the identity information that A2 step is obtained is sent to database compares, if comparison is correct, sends correct signal; If comparison mistake, sends rub-out signal.
The invention solves the defect existing in existing background technology, in the situation that not needing manual intervention, while distinguishing out in vitro fertilization and embryo transfer by REID, be loaded with sperm, ovum, embryo's double dish and the identity information of parent identification ring, and by recognition to identity information compare, send correct signal or rub-out signal, thereby guaranteed the accuracy of in vitro fertilization and embryo transfer.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the present invention is further described.
Fig. 1 is the basic flow sheet of in vitro fertilization in an embodiment of the present invention and embryo transfer information checking method.
Embodiment
Below with reference to embodiment shown in the drawings, describe the present invention.But these embodiments do not limit the present invention, the conversion in the structure that those of ordinary skill in the art makes according to these embodiments, method or function is all included in protection scope of the present invention.
Please refer to shown in Fig. 1, in vitro fertilization and embryo transfer information checking method of the present invention, the method comprises the steps:
A1, the corresponding identity information of sperm, ovum, embryo and parent is stored in database.Researchist works out the relevant identity information of in vitro fertilization and embryo transfer, for example date of operation, numbering, male parent's title or name, parent title or name.If there is repetition, can add other information, such as blood group, hair color etc.This information should have uniqueness, and each relevant identity information in vitro fertilization and the relevant identity information of embryo transfer and the in vitro fertilization and embryo transfer of other batches does not have repetition.According to experiment or operation arrangement, in advance all identity informations in vitro fertilization and embryo transfer are entered in database by software and make corresponding RF ID label.RFID label is attached to respectively on the corresponding double dish that is loaded with sperm, ovum, embryo and parent identification ring.
A2, by radio-frequency technique, identify current sperm, ovum, embryo's double dish and the relevant identity information of parent identification ring of being loaded with.When sperm, ovum, cultivate respectively processing can reach condition in vitro fertilization time, researchist takes out respectively a sperm double dish and its corresponding ovum double dish is placed on operating platform in vitro fertilization.On operating platform in vitro fertilization, FRID recognizer senses RFID label, reads voluntarily the RFID label data of sperm double dish and ovum double dish, and the identity information obtaining is sent to database; When embryo and parent develop into respectively can reach embryo transfer condition time, researchist takes out an Embryo Culture ware to be placed in embryo transfer operating platform, corresponding parent is positioned on embryo transfer platform, on embryo transfer platform, FRID recognizer senses RFID label, the RFID label data that reads voluntarily Embryo Culture ware and parent identification ring, is sent to database by the identity information obtaining.
A3, search database, whether the identity information that comparison obtains mates with database, and if so, pairing is correctly; If not, match mistake.The Embryo Culture ware that on the sperm double dish that database comparison is obtained and ovum double dish, identity information or comparison are obtained and the identity information on parent identification ring.If consistent, send normal signal, utilize acousto-optic or Liquid Crystal Module display notification researchist to compare correctly, remind researchist can carry out next step operation; If inconsistent, send abnormal signal, utilize acousto-optic or Liquid Crystal Module display notification researchist to compare incorrect, remind researchist to suspend next step operation.
Above foundation desirable embodiment of the present invention is enlightenment, and by above-mentioned description, related personnel can, within not departing from the scope of this invention technological thought, carry out various change and modification completely.The technical scope of this invention is not limited to the content on instructions, must determine technical scope according to claim scope.