CN103751870A - Mini automatic peritoneal dialysis machine and operation method thereof - Google Patents

Abstract

The invention discloses and provides a mini automatic peritoneal dialysis machine and an operation method thereof. The mini automatic peritoneal dialysis machine comprises an irrigation and discharge channel communicated with an abdominal cavity of a human body, a waste discharge channel for discharging the liquid discharged from the abdominal cavity through the irrigation and discharge channel, and a liquid supply channel for being connected with a liquid bag accommodating dialysate. The irrigation and discharge channel, the waste discharge channel and the liquid supply channel are correspondingly connected with three liquid flow openings in non-uniform distribution of a first three-way valve. The irrigation and discharge channel further comprises a two-way irrigation and discharge pump. The liquid supply channel further comprises a heater, a heat pump and a second three-way valve, and the second three-way valve is connected with a circulation channel which is connected with the liquid supply channel. The mini automatic peritoneal dialysis machine and the operation method thereof solve the technical problem by overcoming the disadvantages of complex system structure, high machining accuracy requirements and complex operations of an existing peritoneal dialysis transfusion system.

Description

Small automatic peritoneal dialysis machine and operational approach thereof

Technical field

The present invention relates to medical instruments field.Be specially small automatic peritoneal dialysis machine and operational approach thereof.

Background technology

Peritoneal dialysis (Peritoneal Dialysis, english abbreviation PD) is a kind of one of more effective blood purification mode at present, is applicable to carry out after human body injury of kidney the surrogate therapeutic of renal function.Its cardinal principle is that aseptic, the apyrogenic dialysis solution preparing is poured into patient's peritoneal cavity through conduit, utilize the semipermeable membrane characteristic of peritoneum to carry out disperse, infiltration, exchange, and constantly change by abdominal dialysis liquid, reach and remove internal metabolism refuse or toxin, and correct the object of water, electrolyte, acid base imbalance.The operation principle of peritoneal dialysis treatment is to intraperitoneal perfusion dialysis solution and retains after a period of time, the waste liquid after exchange is got rid of external, by perfusion, stop, discharge three important steps and form.Peritoneal dialysis mainly contain two types, continue non-bed peritoneal dialysis (english abbreviation CAPD) and automatization's peritoneal dialysis (english abbreviation APD).CAPD is manually-operated, and change 3-5 every day, conventionally each 2000ml, and APD realizes by peritoneal dialysis machine.Peritoneal dialysis machine or be called cycler (Cycler), patient stays at home and carries out every night conventionally, and a plurality of liquid bags perfusions, the whole loop control process that stops, discharges are completed automatically by machine.

APD is the peritoneal dialysis technology of a develop rapidly in recent years, and it not only can help to solve the technical problem of patient's long-term treatment, can also help the patient of many renal failures to reintegrate into society, and is society, family's creation of value.The technological core of APD is liquid supplying way, particularly patent CN1829545B, 200680012708.2 representative for current APD liquid supplying way.But in its fluid administration system design, all adopted numerous special valves or air door to carry out logical combination, to realize the break-make of each pipeline, controlled, cause its pipeline structure design complicated, requirement on machining accuracy is high, thereby cost is very high, and its operation more complicated.

Summary of the invention

The technical problem that the present invention solves is to overcome that the required precision of existing peritoneal dialysis transfusion system complex structure, processing is high, the shortcoming of complicated operation, and a kind of simple in structure, small automatic peritoneal dialysis machine of being easy to processing and simple operation is provided.

Small automatic peritoneal dialysis machine of the present invention, comprise the filling row passage for being connected with human abdominal cavity, the liquid feeding channel that the waste discharge passage of discharging for the liquid that the row's of filling passage is discharged from intraperitoneal is connected with the liquid bag for holding dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with three liquid communication mouths of the first three-way valve and realize the connection under a certain state between each two respective channel in passage at least between two, described filling row passage is also provided with the row's of filling pump, described filling row pump is that two-way pump is to control the row's of filling passage liquid stream direction, described liquid feeding channel is also provided with for heating the heater of dialysis solution and described dialysis solution being pumped into the heat pump of described heater, described liquid feeding channel is also provided with the second three-way valve, described the second three-way valve is between described the first three-way valve and described heat pump, two liquid communication mouths of described the second three-way valve are all connected with described liquid feeding channel, another liquid communication mouth of described the second three-way valve is connected with circulation canal, described circulation canal is connected with described liquid feeding channel.

As preferably, between described at least two respective channel, the connection of a certain state comprises filling with between row's passage and waste discharge passage and is communicated with, fill with between row's passage and liquid feeding channel and be communicated with, between liquid feeding channel and waste discharge passage, be communicated with, or being communicated with between the row's of filling passage and waste discharge passage and three passages of liquid feeding channel.

As preferably, described the first three-way valve and the second three-way valve include valve body and spool, described spool has at least three liquid flowing channels that communicate with each other and connect, and described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.

As preferably, the valve body of described the first three-way valve and the second three-way valve is the cylindric valve body with inner core, described the first three-way valve and the second three-way valve spool be the inwall that is positioned at described valve body and is close to described valve body, cylindrical spool with respect to described valve body rotation, described spool has three described liquid flowing channels that communicate with each other and connect, three described liquid flowing channels form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T shape or Y shape two arm portions is equal in length with vertical section, described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.

As preferably, described spool is connected with the driving device that drives described Spool rotating, when three described liquid flowing channels are when the projection of horizontal plane forms " Y ", wherein the angle between the projection of two liquid flowing channels is 60 °, and the angle between the projection of another liquid flowing channel and the projection of these two liquid flowing channels is 150 °.

As preferably, described spool is connected with the driving device that drives described Spool rotating.

As preferably, described filling row's pump and/or described heat pump are peristaltic pump or membrane pump.

As preferably, described heater is heating bag, and described heating bag comprises bag and be positioned at the heating plate of described bag one or both sides, and described bag has and is connected logical inlet and liquid outlet with feed liquid pipeline.

As preferably, described filling row passage is provided with at least one for detection of the first via pressure transducer of the pressure in described filling row passage, described first via pressure transducer is between abdominal cavity and the row's of filling pump, described liquid feeding channel is provided with at least one for detection of the second road pressure transducer of the pressure in described liquid feeding channel, and described waste discharge passage is provided with at least one for detection of the Third Road pressure transducer of the pressure in described waste discharge passage.

As preferably, between described first via pressure transducer and described filling row passage, between described the second road pressure transducer and described liquid feeding channel and be equipped with barrier film device between described Third Road pressure transducer and described waste discharge passage.

As preferably, described filling row passage, liquid feeding channel and/or waste discharge passage are also provided with at least one for detection of the temperature sensor of the temperature of dialysis solution, and/or described filling row's passage, liquid feeding channel and/or waste discharge passage and be located between the temperature sensor of this passage and be provided with barrier film device.

As preferably, described filling row's passage and/or waste discharge passage are provided with at least one flow transducer and/or weight sensor and/or optical pickocff, each passage and be located at flow transducer on this passage and/or weight sensor and/or optical pickocff between be provided with barrier film device.

As preferably, described barrier film device comprises housing and the barrier film that is positioned at described housing, and the inner chamber that described barrier film surrounds described housing is partitioned into and the row's of filling passage or liquid feeding channel or waste discharge passage the first chamber being connected and the second chamber being connected with described temperature sensor or described pressure transducer.

As preferably, described barrier film is discharged in fluid by the granule without coming off or shot and the good material of biocompatibility is made, as silicone, polyurethane, Biopure^tM, Kraton^tM, Pebax^tMor Santoprene^tMin any material make.

As preferably, the liquid conveying system of described peritoneal dialysis also comprises control device, and the driving device of described control device and described first via pressure transducer, the second road pressure transducer, Third Road pressure transducer, the first three-way valve, the second three-way valve, the row's of filling pump and heat pump are connected with according to the pressure of the row of filling passage, liquid feeding channel and waste discharge passage or driving device, the row's of filling pump and heat pump that the relation between each channel pressure is controlled the first three-way valve and the second three-way valve.

As preferably, described control device is also connected according to the temperature of dialysis solution, to control the first three-way valve and/or the second three-way valve and/or the row's of filling pump and/or heat pump and/or heater with heater with described temperature sensor.

As preferably, the flow transducer of described control device and described filling row's passage and/or waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.

As preferably, described filling row passage, liquid feeding channel and waste discharge passage consist of the tube for transfusion being tightly connected with described the first three-way valve, the second three-way valve and heater.

As preferably, described filling row passage, liquid feeding channel, waste discharge passage, pump line and three-way valve are integrated in a replaceable cartridge.

As preferably, described heater comprises to be located in described replaceable cartridge and to allow the water back that described dialysis solution passes through and be located in described replaceable cartridge for heating plate or the heating film of the dialysis solution transferring heat in described water back, and the inlet of described water back and liquid outlet are all connected with described liquid feeding channel.

The present invention also provides a kind of operational approach of above-mentioned small automatic peritoneal dialysis machine, comprises following operator scheme:

Circulating-heating pattern: regulating the second three-way valve to make the first section of liquid feeding channel is that the second three-way valve communicates with circulation canal with the section between dialyzate bag, simultaneously the second section of liquid feeding channel is between the section between the second three-way valve and the first three-way valve and the first section and be all cut off between the second section and circulation canal, open heat pump, dialysis solution flows out from dialyzate bag under the effect of heat pump, and flows into heater by rear liquid feeding channel the first section and the circulation canal of flowing into of heater heating;

Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulate the first three-way valve make to fill with row's passage with the second section of liquid feeding channel communicate, between the second section of waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, be all cut off, regulate the second three-way valve that the second section of liquid feeding channel is communicated with the first section, open the operative orientation that row's pump is filled with in the row's of filling pump setting, the operative orientation of the row's of filling pump makes dialysis solution pass through the first section of liquid feeding channel, the second three-way valve, the second section of liquid feeding channel and the first three-way valve enter the row's of filling passage and flow to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity,

Waste discharge pattern: regulate the first three-way valve to make the row's of filling passage and waste discharge channel connection, the second section of liquid feeding channel and filling are arranged between passage and are cut off between liquid feeding channel and waste discharge passage, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid enter waste discharge passage and flow out arranging passage, the first three-way valve by filling, thereby realize, Intraabdominal waste liquid is excreted.

As preferably; also comprise overtemperature protection pattern: when liquid feeding channel or while filling with the temperature range that the temperature of the dialysis solution in row's passage requires higher than perfusion; close the row's of filling pump and heater; regulating three-way valve; liquid feeding channel is connected with waste discharge passage; simultaneously; fill with between row's passage and liquid feeding channel and the row's of filling passage and waste discharge passage between be communicated with and be cut off; overheated dialysis solution liquid self-feeding passage, three-way valve and waste discharge passage are discharged; or during the temperature range that the temperature of the dialysis solution in liquid feeding channel or the row's of filling passage requires higher than perfusion, enter waste discharge pattern.

As preferably, before fill-up mode, also have pipeline is carried out to pre-pattern of rinsing, be specially: regulate the first three-way valve that the second section of liquid feeding channel is all communicated with the row's of filling passage and waste discharge passage, regulate the second three-way valve to make the second section of liquid feeding channel, the first section and the circulation canal logical dialysis solution of homogeneous phase that communicates is flowed through and is full of liquid feeding channel the first section from dialyzate bag under the effect of heat pump and the row's of filling pump, circulation canal, the second three-way valve, liquid feeding channel the second section, the first three-way valve, the row's of filling passage and waste discharge passage are also discharged from the row's of filling passage and waste discharge passage, the pre-flushing of realization to pipeline.

The present invention also provides the another kind of operational approach of above-mentioned small automatic peritoneal dialysis machine, comprises following operator scheme:

Circulating-heating pattern: regulating the second three-way valve to make the first section of liquid feeding channel is that the second three-way valve communicates with circulation canal with the section between dialyzate bag, the second section of liquid feeding channel is between the section and the first section between the second three-way valve and the first three-way valve simultaneously, and second be all cut off between section and circulation canal, open heat pump, dialysis solution flows out from dialyzate bag under the effect of heat pump, flow into heater by rear the first section and the circulation canal that flows into liquid feeding channel of heater heating, Data Control the second three-way valve that control device transmits according to the temperature sensor of the first section setting of liquid feeding channel, heat pump and heater, during the temperature of dialysis solution requires lower than perfusion in the first section of liquid feeding channel temperature range, continue heating, when in the first section of liquid feeding channel, the temperature of dialysis solution meets the temperature range of perfusion requirement, enter fill-up mode,

Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulate the first three-way valve that the row's of filling passage is communicated with the second section of liquid feeding channel, between the second section of waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, be all cut off, regulate the second three-way valve that the second section of liquid feeding channel is communicated with the first section, open the operative orientation that row's pump is filled with in the row's of filling pump setting, the operative orientation of the row's of filling pump makes dialysis solution pass through the first section of liquid feeding channel, the second three-way valve, the second section of liquid feeding channel and the first three-way valve enter the row's of filling passage and flow to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity, first via pressure transducer detects pressure and/or second road pressure transducer detection filling row's channel pressure of liquid feeding channel and feeds back to control device simultaneously, control device is according to numerical control the first three-way valve of receiving, the second three-way valve, the action of the row's of filling pump and heat pump,

Waste discharge pattern: in the time of need to discharging the waste liquid in human abdominal cavity according to treatment requirement, control device regulates the first three-way valve to make the row's of filling passage and waste discharge channel connection, the second section of liquid feeding channel and filling are arranged between passage and are cut off between liquid feeding channel and waste discharge passage, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid enter waste discharge passage and flow out arranging passage, the first three-way valve by filling, thereby realize, Intraabdominal waste liquid is excreted.

As preferably, when the pressure of liquid feeding channel and/or the row's of filling channel pressure numerical value reach the first setting value, control device is controlled small automatic peritoneal dialysis machine and is entered waste discharge pattern

As preferably, control device calculates the pressure of liquid feeding channel and the pressure of the row's of the filling passage difference between the two, when difference reaches the second setting value, controls small automatic peritoneal dialysis machine and enters waste discharge pattern.

As preferably, also comprise overtemperature protection pattern: when liquid feeding channel or while filling with the temperature range that the temperature of dialysis solution in row's passage requires higher than perfusion, control device cuts out the row's of filling pump and heater according to the data of temperature sensor feedback, regulate the first three-way valve that liquid feeding channel is connected with waste discharge passage and make and cut off between the row's of filling passage and liquid feeding channel and between the row's of filling passage and waste discharge passage, control device also regulates the second three-way valve that the first section of liquid feeding channel is communicated with the second section simultaneously, make overheated dialysis solution through liquid feeding channel, the second three-way valve, the first three-way valve and waste discharge passage are discharged, or during the temperature range that the temperature of dialysis solution requires higher than perfusion in liquid feeding channel or the row's of filling passage, control device is controlled small automatic peritoneal dialysis machine and is entered waste discharge pattern.

As preferably, control device calculates the amount of the dialysis solution that each perfusion used and the dialysis solution cumulative amount that repeatedly perfusion is used according to filling with data that flow transducer on row's passage and/or weight sensor and/or optical pickocff transmit, and the data that control device transmits according to the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff can calculate the amount of waste liquid and the cumulative amount of the waste liquid that repeatedly waste discharge is discharged that each waste discharge is discharged.

Compared to the prior art small automatic peritoneal dialysis machine of the present invention and operational approach thereof, have following beneficial effect:

1, thereby the present invention only can at least be completed to patient's intraperitoneal perfusion dialysis solution, from the outside drained liquid in patient abdominal cavity, when dialysate temperature is too high, be made dialysis solution carry out several operations such as overtemperature protection at liquid feeding channel and circulation canal internal recycle by the first three-way valve, the second three-way valve and two-way filling row pump; the valve numerous with existing dependence carries out the incompatible technology that realizes the switching of multiple operation of logical groups of break-make and compares; greatly simplify the structure; reduced the requirement to machining accuracy; thereby make its cost, also make easy and simple to handle reliable simultaneously.Meanwhile, the present invention, by the second three-way valve and circulation canal, can realize the circulating-heating to dialysis solution, makes the temperature of the dialysis solution after being heated more even, thereby can bring into play more fully its function.

2, simple in structure, the reliable operation of its first three-way valve and the second three-way valve, and its spool drives by electrohydraulic valve actuator machine, the spinning movement that can make spool more accurately, reliable.

3, it fills with row's pump and heat pump adopts membrane pump or peristaltic pump, and the inwall that prevents pump contacts with dialysis solution and pollutes dialysis solution.

4, its temperature sensor is all connected with passage by barrier film device with pressure transducer, can prevent that temperature sensor from directly contacting with dialysis solution with pressure transducer and polluting dialysis solution.

5, its control device can be related to control valve drive motors between the pressure of row passage, liquid feeding channel and waste discharge passage or each channel pressure according to filling with, make the first three-way valve automatically adjust to the position needing, avoided operator to forget or delayed the problem that operation produces; Control device can also be according to the real-time control heater of Temperature numerical of temperature sensor feedback, and controls whole small automatic peritoneal dialysis machine and enter perfusion state or overtemperature protection state.

Accompanying drawing explanation

Fig. 1 is the structural representation of an embodiment of small automatic peritoneal dialysis machine of the present invention.

Fig. 2 is the position view when different operations of the first three-way valve of small automatic peritoneal dialysis machine of the present invention.

Fig. 3 is the schematic diagram of small automatic peritoneal dialysis machine of the present invention while carrying out the operation of pre-irrigation channel.

Fig. 4 is the schematic diagram of small automatic peritoneal dialysis machine of the present invention while carrying out operating to patient's intraperitoneal perfusion dialysis solution.

Fig. 5 is the schematic diagram of small automatic peritoneal dialysis machine of the present invention while carrying out the operation from the outside drained liquid in patient abdominal cavity.

Fig. 6 is that small automatic peritoneal dialysis machine of the present invention carries out the overtemperature protection schematic diagram in when operation.

Fig. 7 is the structural representation of the first three-way valve of small automatic peritoneal dialysis machine of the present invention, and wherein left figure is the cross sectional representation of the first three-way valve, and right figure is the longitudinal section of the first three-way valve and the structural representation of electrohydraulic valve actuator machine.

Fig. 8 is the schematic diagram of the peristaltic pump of small automatic peritoneal dialysis machine of the present invention.

Fig. 9 is the schematic diagram of the barrier film device of small automatic peritoneal dialysis machine of the present invention.

Figure 10 is the cartridge type schematic diagram of small automatic peritoneal dialysis machine of the present invention.

Reference numeral

1-fills with row's passage, 2-liquid feeding channel, 3-waste discharge passage, 4-the first three-way valve, 5-the second three-way valve, 6-fills with row's pump, 7-liquid bag, 8-heater, 9-heat pump, 10-valve body, 11-spool, 11a-spool rear end, 12-liquid flowing channel, 13-liquid communication mouth, 14-electrohydraulic valve actuator machine, 15-pump head, 16-pump drive motors, 17-roller, 18-knob, 19-temperature sensor, 20-barrier film device, 21-first via pressure transducer, 22-the second road pressure transducer, 23-Third Road pressure transducer, 24-housing, 25-barrier film, 26-the first chamber, 27-the second chamber, 28-pump line, 29-the first joint, 30-the second joint, 31-control device, 32-circulation canal.

The specific embodiment

The structural representation of an embodiment of Fig. 1 small automatic peritoneal dialysis machine of the present invention.As shown in Figure 1, small automatic peritoneal dialysis machine of the present invention, comprises the row offilling passage 1,liquid feeding channel 2 andwaste discharge passage 3, and describedfilling row passage 1,liquid feeding channel 2 are connected with threeliquid communication mouths 13 of the first three-way valve 4 correspondingly with waste discharge passage 3.In the present embodiment, threeliquid communication mouth 13 right and wrong are equally distributed.Describedfilling row passage 1 is also provided with the row's offilling pump 6, and describedfilling row pump 6 is two-way pump.Describedliquid feeding channel 2 be provided with for or connect hold dialysissolution liquid bag 7, for heatliquid feeding channel 2dialysis solution heater 8 and the dialysis solution in describedliquid bag 7 is pumped into theheat pump 9 ofheater 8, in the present embodiment,heat pump 9 is betweenliquid bag 7 and heater 8.Describedliquid feeding channel 2 is also provided with the second three-way valve 5, described the second three-way valve 5 is between described the first three-way valve 4 and describedheat pump 9, twoliquid communication mouths 13 of described the second three-way valve 5 are all connected with describedliquid feeding channel 2, anotherliquid communication mouth 13 of described the second three-way valve 5 is connected withcirculation canal 32, and describedcirculation canal 32 is connected with described liquid feeding channel 2.In the present embodiment, the second three-way valve 5 is connected with the end that liquid feeding channel is provided with one end of liquid bag.

In the present invention, " the first three-way valve " and " the second three-way valve " refers to have at least threeliquid communication mouths 13, and can realize following operation: threeliquid communication mouths 13 all communicate with each other, or threeliquid communication mouths 13 are not all communicated with, or in threeliquid communication mouths 13 any two are interconnected, anotherliquid communication mouth 13 is closed simultaneously.Therefore, the first three-way valve 4 of the present invention and the second three-way valve 5 can adopt the multiposition valve of various concrete forms and structure, as long as realize above function.

In the present invention, between described at least two respective channel, the connection of a certain state comprises filling with between row's passage and waste discharge passage and is communicated with, fill with between row's passage and liquid feeding channel and be communicated with, between liquid feeding channel and waste discharge passage, be communicated with, certainly, fill with between row's passage and waste discharge passage and three passages of liquid feeding channel and also can all be communicated with under a certain state.

In the present invention, " two-way pump " refers to that can realize inlet is switching to the pump that liquid outlet while liquid outlet is switching to inlet,, can realize the pump that flow direction can be switched at positive and negative both direction that is.

In the present invention, as preferred scheme, described the first three-way valve 4 and the second three-way valve 5 include valve body and spool, described spool has at least three liquid flowing channels that communicate with each other and connect, and described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.

As further preferred, the valve body of the first three-way valve 4 and the second three-way valve 5 is thecylindric valve body 10 with inner core, spool is to be positioned at describedvalve body 10 and can be close to the inwall of describedvalve body 10, thecylindrical spool 11 rotating with respect to describedvalve body 10, as shown in Figure 7, describedspool 11 has three and communicates with each other and connectliquid flowing channel 12, three liquid flowingchannels 12 form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T shape or Y shape two arm portions and vertical section is equal in length.In the present embodiment, three liquid flowingchannels 12 are "T"-shaped in the projection formation of horizontal plane, and wherein two liquid flowingchannels 12 are arranged in same level, and anotherliquid flowing channel 12 is arranged on another horizontal plane.Describedvalve body 10 is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the describedliquid communication mouth 13 of the corresponding connection of different conditions.

In other embodiment, three liquid flowing channels also can form " Y " shape (not shown) jointly, as, when three described liquid flowing channels are when the projection of horizontal plane forms " Y ", wherein the angle between the projection of two liquid flowing channels is 60 °, angle between the projection of the projection of another liquid flowing channel and these two liquid flowing channels is 150 °, between certain three liquid flowing channels, also can be other angles.

Certainly, spool also can arrange more liquid flowing channels, and liquid flowing channel can evenly arrange, and also can non-homogeneously arrange, as long as can realize several situations that communicate or disconnect between above-mentioned said three liquid communication mouths.

By above scheme, small automatic peritoneal dialysis machine of the present invention at least can be realized following operation: to patient's intraperitoneal perfusion dialysis solution, from the outside drained liquid in patient abdominal cavity, to dialysis solution circulating-heating.

Small automatic peritoneal dialysis machine of the present invention also can be realized pre-flushing operation, Fig. 3 is the schematic diagram of small automatic peritoneal dialysis machine of the present invention while carrying out the operation of pre-irrigation channel, as shown in Figure 3, when passage is rinsed in advance, three liquid flowing channels 12 of the first three-way valve 4 are relative one by one with three liquid communication mouths 13, as shown in left several the 1st figure in Fig. 2, liquid feeding channel 2, the row's of filling passage 1 and waste discharge passage 3 are all communicated with each other.Simultaneously three liquid flowing channels 12 of the second three-way valve 5 and three liquid communication mouths 13 are relative one by one makes liquid feeding channel 2 and circulation canal 32 connections.The now row's of filling pump 6 forward runnings make liquid flow to the left in figure.Dialysis solution under the effect of heat pump 9 after liquid feeding channel 2 and the second three-way valve 5, thereby a road enters circulation canal 32 is full of circulation canal 32 and liquid feeding channel 2, another road is divided into again two-way after entering the second three-way valve, wherein a road enters waste discharge passage 3 and is full of waste discharge passage 3, another road enters liquid feeding channel 1 and is full of liquid feeding channel 1, and the flow direction of dialysis solution is as shown in the arrow in Fig. 3.Dialysis solution can stop pre-flushing operation after being full of the row of filling passage 1, waste discharge passage 3 and circulation canal 32, and this operation can be driven the air in each passage away and passage is cleaned.

Fig. 4 is the schematic diagram of small automatic peritoneal dialysis machine of the present invention while carrying out operating to patient's intraperitoneal perfusion dialysis solution, as shown in Figure 4, during to patient's intraperitoneal perfusion dialysis solution, two liquid flowingchannels 12 of the second three-way valve 5 are aimed at theliquid communication mouth 13 being connected withliquid feeding channel 2, make dialysis solution throughliquid feeding channel 2, enter anotherliquid flowing channel 12 sealings of the first three-way valve 4, the second three-way valve 5.Simultaneously, two liquid flowingchannels 12 of the first three-way valve 4 are aimed at twoliquid communication mouths 13 that are connected with fillingrow passage 1 withliquid feeding channel 2 respectivelyliquid feeding channel 2 and the row's of fillingpassage 1 are connected by the first three-way valve 4, anotherliquid flowing channel 12 is closed, as shown in left several the 2nd figure in Fig. 2.The now row's of fillingpump 6 forward runnings, make liquid flow to the left in figure,, flow into the intraperitoneal of human body that is.The flow direction of dialysis solution is as shown in the arrow in Fig. 4.Now can open heater heats dialysis solution.

Fig. 5 is the schematic diagram of small automatic peritoneal dialysis machine of the present invention while carrying out the operation from the outside drained liquid in patient abdominal cavity, as shown in left several the 3rd figure in Fig. 5 and Fig. 2, two liquid flowing channels 12 of the first three-way valve 4 are aimed at two liquid communication mouths 13 that are connected with waste discharge passage 3 with filling row passage 1 respectively the row's of filling passage 1 and waste discharge passage 3 are connected by the first three-way valve 4, and another liquid flowing channel 12 is closed.Fill with row's pump 6 antiports, liquid in abdominal cavity is flowed out and enter the row's of filling passage 1, and then enter waste discharge passage 3 and discharge.Now, the second three-way valve 5 can, in any position, all not affect the waste discharge of waste discharge passage.If three liquid flowing channels 12 of the second three-way valve 5 and three liquid communication mouths 13 are corresponding (as shown in Figure 5) one by one, or a fluid flow passages 12 communicates with the liquid feeding channel 2 of its upstream, another liquid flowing channel 13 communicates with circulation canal 32, another liquid flowing channel 12 sealings, carry out circulating-heating to dialysis solution when can realize from the outside drained liquid in patient abdominal cavity.Now, the flow direction of liquid as shown in Figure 5.

Fig. 6 is that small automatic peritoneal dialysis machine of the present invention carries out the overtemperature protection schematic diagram in when operation; when the temperature of perception dialysis solution is during higher than body temperature; make two liquid flowing channels 12 of the second three-way valve 5 aim at respectively two liquid communication mouths 13 that are connected with liquid feeding channel 2; another liquid flowing channel 12 sealings, make dialysis solution enter the first three-way valve 4 through liquid feeding channel 2.Make two liquid flowing channels 12 of the first three-way valve 4 aim at two liquid communication mouths 13 that are connected with waste discharge passage 3 with liquid feeding channel 2 respectively makes liquid feeding channel 2 and waste discharge passage 3 be connected by the first three-way valve 4 simultaneously, another liquid flowing channel 12 sealings, as shown in left several the 4th figure in Fig. 2.Now, the row's of filling pump 6 is out of service, heat pump operation.As shown in the arrow of Fig. 6, dialysis solution is discharged through waste discharge passage 3, prevents that dialysis solution higher than body temperature from entering human body health of human body is worked the mischief.The overtemperature protection operation of small automatic peritoneal dialysis machine of the present invention is compared with the existing mode that overheated dialysis solution is drained, and can avoid the waste of expensive dialysis solution.

Small automatic peritoneal dialysis machine of the present invention only can complete above-mentioned all operations by two three-way valve, two-way filling row's pump and unidirectional heat pump, carry out the technology of the incompatible realization perfusion of different logical groups and waste discharge compares with tens valves of existing dependence, greatly simplify the structure, reduced the requirement to machining accuracy, thereby make its cost, also make easy and simple to handle reliable simultaneously.

In the present embodiment, the first three-way valve 4 is identical with the structure of the second three-way valve 5, the structure of the first three-way valve 4 of take is below described as example, the spoolrear end 11a connecting drive device of the first three-way valve 4, driving device is preferably electrohydraulicvalve actuator machine 14, as shown in Figure 7, left figure is the cross sectional representation of the first three-way valve 4, right figure is the longitudinal section of the first three-way valve 4 and the schematic diagram of electrohydraulicvalve actuator machine 14, can pass through operatingvalve drive motors 14,spool 11 is rotated to the position needing to carry out corresponding pre-flushing, to intraperitoneal perfusion dialysis solution, from operations such as abdominal cavity drained liquid or overtemperature protections.Certainly driving device also can adopt the driving device of other actuatable valve core rotations.As, can be controlled by a mechanical energy rotary apparatus, this mechanical energy rotary apparatus is designed to a knob or rotary handle, and other mechanisms that rotate by mechanical energy.

As of the present invention preferred, described filling row'spump 6 and describedheat pump 9 are peristaltic pump or membrane pump, and dialysis solution can not contacted with the inwall of pump, prevent other materials to bring in human body human body is worked the mischief.Wriggling pump structure as shown in Figure 8, left figure is the front view of peristaltic pump, right figure is the assembly structure figure of peristaltic pump, and peristaltic pump comprisespump head 15,flexible pump line 28 and thepump drive motors 16 that drivespump head 15 to rotate, and pumphead 15 is provided with a plurality of rollers that are evenly arranged 17.Pump head 15 is also provided withbearing 18, and is connected withpump drive motors 16 by bearing 18.

Well-known in this area, it is directly related that the efficiency of peritoneal dialysis and liquid rest on the intraperitoneal time, and the discharge stage can limit with regard to its persistent period, and the function that this persistent period is drainage rate.Conventionally the initial discharge process of CAPD is 200ml/min left and right, and along with patient's intra-abdominal pressure reduces, this drainage rate also decreases, and has also just directly affected whole dialysis time.Therefore,, in the design of APD, how dynamic adjustments, for the pump speed of the row of filling, seems particularly important to improve dialytic efficiency.

As of the present invention preferred, the present invention has given a solution: betweenpump head 15 andpump line 28, be designed to two kinds of contact conditions: extrusion pump tubulose state and non-extrusion pump tubulose state.Particularly, by therelated pump head 15 of pump head bearing 18, move up and down to realize the conversion of two kinds of states, wherein also comprised thatpump drive motors 16 is rotated and given kinetic energy by the gear inpump head 15.

When under extrusion pump tubulose state, duringpump head 15 rotation, theflexible pump line 28 of roller 17 extruding, the direction of the liquid runs down extruding inflexible pump line 28 is flowed, now can set by the requirement of anticipation the flow velocity of the row's of fillingpump 6, now, also can be by adopting high-precision numeric type, flow type peristaltic pump to calculate each circumfusion amount and the accumulative total groundwater increment of dialysis solution.

Under non-extrusion pump tubulose state, 15 pairs of pump lines ofpump head 28 are not controlled, guarantee to start to rely on Intraabdominal pressure to realize the excretion naturally of waste liquid in discharge process, and when intra-abdominal pressure reduces and be unworthy continuing nature excretion, change again pump line into squeezed state, now also by the pressure differential between a plurality of pressure transducers, carry out the speed that dynamic adjustments is filled with row'spump 6, can shorten the time of discharge process on the one hand, guarantee the groundwater increment dischargeable capacity of next circulation, to improve dialytic efficiency, also to guarantee that on the other hand drainage rate is the tolerance interval of patient safety.After this, also will the effect of described pressure transducer be described.

Certainly, these are only preferred scheme, also can adopt other to make liquid and the discontiguous pump of pump, and can meet the operation requirements of the required perfusion of peritoneal dialysis, reservation, discharge process.

Heater 8 is preferably heating bag, and described heating bag comprises bag and be positioned at the heating plate of bag one or both sides, and described bag has and is connected logical inlet and liquid outlet with feed liquid pipeline.In order to guarantee the efficiency of heating surface and homogeneous heating, heating bag is when including heating film or realizing heating function by outside heating plate, in structure, can be designed to the composition form by a plurality of dog leg pipings, guarantee that liquid flows into fromheater 8 inlets, mode with one-way flow and the given flow velocity of maintenance, flows out fromheater 8 liquid outlets.

As preferably, described fillingrow passage 1,liquid feeding channel 2 and/orwaste discharge passage 3 are also provided with at least one for detection of thetemperature sensor 19 of the temperature of dialysis solution.In the present embodiment, described filling row'spassage 1 andliquid feeding channel 2 are equipped with a temperature sensor, andwaste discharge passage 3 can arrange also not set temperature sensor.Temperature sensor is more reliable than the temperature of human perception dialysis solution, can detect more accurately, more in time the temperature of dialysis solution, prevents that overheated or excessively cool dialysis solution from flowing into human body.Described filling row'spassage 1,liquid feeding channel 2 and/orwaste discharge passage 3 and be located between the temperature sensor of this passage and be provided with barrier film device.Can preventtemperature sensor 19 from contacting with dialysis solution and pollute dialysis solution.

Well-known in this area, in peritoneal dialysis process, the pressure measxurement of the row of filling is a very important factor with control, if particularly link pressure increase on patient's pipeline, exceeds warning and limits, and may produce serious injury to patient.As preferably, described filling row passage 1 is provided with the first via pressure transducer 21 for detection of the pressure in described filling row passage 1, described liquid feeding channel 2 is provided with the second road pressure transducer 22 for detection of the pressure in described liquid feeding channel 2, and described waste discharge passage 3 is provided with the Third Road pressure transducer 23 for detection of the pressure in described waste discharge passage 3.Described first via pressure transducer 21 is between abdominal cavity and the row's of filling pump 6, and described the second road pressure transducer 22 is between described the first three-way valve 4 and described the second three-way valve 5.By each pressure transducer, can know the pressure of each passage, scalable three-way valve or relevant pump when pressure is excessive, damage patient preventing.In the present embodiment, between described first via pressure transducer 21 and described filling row passage 1, between described the second road pressure transducer 22 and described liquid feeding channel 2 and be equipped with barrier film device 20 between described Third Road pressure transducer 23 and described waste discharge passage 3, can prevent that pressure transducer from directly contacting with liquid.

The above-mentioned three road pressure transducer main purposes of the present invention's design have following effect: the first, and real-time dynamic monitoring injection pressure and Intraabdominal pressure, guarantee patient's safety with this.The second, in the discharge process of peritoneal dialysis, utilize the variation of pressure reduction between pressure or pipeline, by current meter, calculate the output of each circulation of dialysis solution and add up output.

Described filling row's passage and/or waste discharge passage are provided with at least one flow transducer and/or weight sensor and/or optical pickocff, each passage and be located at flow transducer on this passage and/or weight sensor and/or optical pickocff between be provided with barrier film device.

Describedbarrier film device 20 compriseshousing 24 and is positioned at thebarrier film 25 of describedhousing 24, and as shown in Figure 9, housing can be the cylindricality in the left figure of figure, can also be spherical as in right figure.The inner chamber that describedbarrier film 25 surrounds describedhousing 24 is partitioned into and the row's of fillingpassage 1 orliquid feeding channel 2 orwaste discharge passage 3 thefirst chamber 26 being connected and thesecond chamber 27 being connected with describedtemperature sensor 19 or pressure transducer.The first chamber of barrier film device has for having the second joint 30 for being connected with temperature sensor or pressure transducer with channel attached the first joint 29, the secondchambeies.Temperature sensor 19 can be determined by detecting the temperature of thebarrier film 25 directly contacting with dialysis solution the temperature of dialysis solution.Pressure transducer can change the pressure of determining liquid by air pressure or the pressure detecting in the deformation ofbarrier film 25 or thesecond chamber 27 thatbarrier film 25 deformationcause.Barrier film 25 is discharged in fluid by the granule without coming off or shot and the good material of biocompatibility is made, as is preferably by silicone, polyurethane, Biopure^tM, Kraton^tM, Pebax^tMor Santoprene^tMin any one or several materials make.

As preferably, described small automatic peritoneal dialysis machine also comprises that control device 31(as shown in figure 10), describedcontrol device 10 and described first viapressure transducer 21, the secondroad pressure transducer 22, ThirdRoad pressure transducer 23 and driving device, the row's of fillingpump 6,heat pump 9 connects with the pressure of each passage of Real-Time Monitoring and according to the row's of fillingpassage 1, relation between the pressure ofliquid feeding channel 2 andwaste discharge passage 3 or each channel pressure regulates the first three-way valve 4 in time, the second three-way valve 5, the row's of fillingpump 6 andheat pump 9, realize the state that dynamic adjustments is filled with the flow velocity of row'spump 6 and controlled in real time the first three-way valve 4 and the second three-way valve 5, wherein also comprised when patient is with respect to the position of peritoneal dialysis machine (APD) and the change in location of dialyzate bag, and have influence on while pouring into intra-abdominal pressure, consideration should regulate the necessity of flow velocity, make pressure and flow speed control in the most rational scope, thereby bring into play more fully the treatment function of peritoneal dialysis.

In the present embodiment, describedcontrol device 31 is also connected according to the temperature of dialysis solution, to control the first three-way valve 4, the second three-way valve 5, the row of fillingpump 6,heat pump 9 andheater 8 withheater 8 with described temperature sensor 19.Above scheme has realized the automatic control of the liquid conveying system of peritoneal dialysis, makes the action of the first three-way valve 4 and the second three-way valve 5 timely and reliable, has avoided operator to forget or has delayed the problem that operation produces.

The flow transducer that described control device arranges with described filling row'spassage 1 and/orliquid feeding channel 2 and/or weight sensor and/or optical pickocff are connected.

Small automatic peritoneal dialysis machine of the present invention is arranged to pipeline type, that is, described fillingrow passage 1,liquid feeding channel 2 andwaste discharge passage 3 consist of tube for transfusion, and are tightly connected with the first three-way valve 4, the second three-way valve 5 andheater 8, as shown in Figure 1.Wherein, described fillingrow passage 1,liquid feeding channel 2,waste discharge passage 3, the first three-way valve 4, the second three-way valve 5 andheater 8 are made by medical-grade plastics material.

Small automatic peritoneal dialysis machine of the present invention can also integratedly be set to a replaceable cartridge,, described fillingrow passage 1,liquid feeding channel 2,waste discharge passage 3, pump line, three-way valve are integrated in a replaceable cartridge, as shown in figure 10, during use, replaceable cartridge is matched with other devices.Described barrier film device is according to its above-mentioned design principle, also can be incorporated into or design in cartridge, the temperature of dialysis solution can be directly measured in temperature sensor bybarrier film 25, pressure transducer can be distinguished directly by the pressure inbarrier film 25 measurement fillingrow passages 1,liquid feeding channel 2,waste discharge passage 3 and mutual pressure reduction.According to pressure differential pressure, change and cartridge fixed volume, the present invention also can accurately calculate the groundwater increment of dialysis solution, output, and effectively controls the pressure in patient abdominal cavity.

As preferably, describedheater 8 comprises to be located in described replaceable cartridge and to allow the water back that described dialysis solution passes through and be located in described replaceable cartridge for heating plate or the heating film of the dialysis solution transferring heat in described water back, and the inlet of described water back and liquid outlet are all connected with described liquid feeding channel.

The present invention also provides a kind of operational approach of small automatic peritoneal dialysis machine, at least comprises two mode of operations, is specially:

Circulating-heating pattern: regulating the second three-way valve to make the first section of liquid feeding channel is that the second three-way valve communicates with circulation canal with the section between dialyzate bag, simultaneously the second section of liquid feeding channel is between the section between the second three-way valve and the first three-way valve and the first section and be all cut off between the second section and circulation canal, open heat pump, dialysis solution flows out from dialyzate bag under the effect of heat pump, and flows into heater by rear liquid feeding channel the first section and the circulation canal of flowing into of heater heating;

Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulate the first three-way valve make to fill with row's passage with the second section of liquid feeding channel communicate, between the second section of waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, be all cut off, regulate the second three-way valve that the second section of liquid feeding channel is communicated with the first section, open the operative orientation that row's pump is filled with in the row's of filling pump setting, the operative orientation of the row's of filling pump makes dialysis solution pass through the first section of liquid feeding channel, the second three-way valve, the second section of liquid feeding channel and the first three-way valve enter the row's of filling passage and flow to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity,

Waste discharge pattern: regulate the first three-way valve to make the row's of filling passage and waste discharge channel connection, the second section of liquid feeding channel and filling are arranged between passage and are cut off between liquid feeding channel and waste discharge passage, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid enter waste discharge passage and flow out arranging passage, the first three-way valve by filling, thereby realize, Intraabdominal waste liquid is excreted.

As preferably, also comprise overtemperature protection pattern: when liquid feeding channel or while filling with the temperature range that the temperature of the dialysis solution in row's passage requires higher than perfusion, close the row's of filling pump and heater, regulate the first three-way valve, liquid feeding channel is connected with waste discharge passage, simultaneously, fill with between row's passage and liquid feeding channel and the row's of filling passage and waste discharge passage between be communicated with and be cut off, regulate the second three-way valve that the first section of liquid feeding channel is communicated with the second section, overheated dialysis solution liquid self-feeding passage, three-way valve and waste discharge passage are discharged; Or during the temperature range that the temperature of dialysis solution requires higher than perfusion in liquid feeding channel or the row's of filling passage, enter waste discharge pattern.

As preferably, before fill-up mode, also have pipeline is carried out to pre-pattern of rinsing, be specially: regulate the first three-way valve that the second section of liquid feeding channel is all communicated with the row's of filling passage and waste discharge passage, regulate the second three-way valve to make the second section of liquid feeding channel, the first section and the circulation canal logical dialysis solution of homogeneous phase that communicates is flowed through and is full of liquid feeding channel the first section from dialyzate bag under the effect of heat pump and the row's of filling pump, circulation canal, the second three-way valve, liquid feeding channel the second section, the first three-way valve, the row's of filling passage and waste discharge passage are also discharged from the row's of filling passage and waste discharge passage, the pre-flushing of realization to pipeline.

Under ideal case, liquid feeding channel, the row's of filling passage and waste discharge passage are not all communicated with mutually, and close the row's of filling pump.

The present invention also provides the operational approach of another small automatic peritoneal dialysis machine, comprises following operator scheme:

Circulating-heating pattern: regulating the second three-way valve to make the first section of liquid feeding channel is that the second three-way valve communicates with circulation canal with the section between dialyzate bag, the second section of liquid feeding channel is between the section and the first section between the second three-way valve and the first three-way valve simultaneously, and second be all cut off between section and circulation canal, open heat pump, dialysis solution flows out from dialyzate bag under the effect of heat pump, flow into heater by rear the first section and the circulation canal that flows into liquid feeding channel of heater heating, Data Control the second three-way valve that control device transmits according to the temperature sensor of the first section setting of liquid feeding channel, heat pump and heater, during the temperature of dialysis solution requires lower than perfusion in the first section of liquid feeding channel temperature range, continue heating, when in the first section of liquid feeding channel, the temperature of dialysis solution meets the temperature range of perfusion requirement, enter fill-up mode,

Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulate the first three-way valve that the row's of filling passage is communicated with the second section of liquid feeding channel, between the second section of waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, be all cut off, regulate the second three-way valve that the second section of liquid feeding channel is communicated with the first section, open the operative orientation that row's pump is filled with in the row's of filling pump setting, pass through the first section of liquid feeding channel with the contrary dialysis solution of operative orientation under fill-up mode, the second three-way valve, the second section of liquid feeding channel and the first three-way valve enter the row's of filling passage and flow to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity, first via pressure transducer detects pressure and/or second road pressure transducer detection filling row's channel pressure of liquid feeding channel and feeds back to control device simultaneously, control device is according to numerical control the first three-way valve of receiving, the second three-way valve, the action of the row's of filling pump and heat pump,

Waste discharge pattern: in the time of need to discharging the waste liquid in human abdominal cavity according to treatment requirement, control device regulates the first three-way valve to make the row's of filling passage and waste discharge channel connection, the second section of liquid feeding channel and filling are arranged between passage and are cut off between liquid feeding channel and waste discharge passage, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid enter waste discharge passage and flow out arranging passage, the first three-way valve by filling, thereby realize, Intraabdominal waste liquid is excreted.

As preferably, when the pressure of liquid feeding channel and/or the row's of filling channel pressure numerical value reach the first setting value, control device is controlled small automatic peritoneal dialysis machine and is entered waste discharge pattern.

As preferably, control device calculates the pressure of liquid feeding channel and the pressure of the row's of the filling passage difference between the two, when difference is during to the second setting value, controls small automatic peritoneal dialysis machine and enters waste discharge pattern.

As preferably, also comprise overtemperature protection pattern: when liquid feeding channel or while filling with the temperature range that the temperature of dialysis solution in row's passage requires higher than perfusion, control device cuts out the row's of filling pump and heater according to the data of temperature sensor feedback, regulate the first three-way valve that liquid feeding channel is connected with waste discharge passage and make and cut off between the row's of filling passage and liquid feeding channel and between the row's of filling passage and waste discharge passage, control device also regulates the second three-way valve that the first section of liquid feeding channel is communicated with the second section simultaneously, make overheated dialysis solution through liquid feeding channel, the second three-way valve, the first three-way valve and waste discharge passage are discharged, or during the temperature range that the temperature of dialysis solution requires higher than perfusion in liquid feeding channel or the row's of filling passage, control device is controlled small automatic peritoneal dialysis machine and is entered waste discharge pattern.

As preferably, control device calculates the amount of the dialysis solution that each perfusion used and the dialysis solution cumulative amount that repeatedly perfusion is used according to filling with data that flow transducer on row's passage and/or weight sensor and/or optical pickocff transmit, and the data that control device transmits according to the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff can calculate the amount of waste liquid and the cumulative amount of the waste liquid that repeatedly waste discharge is discharged that each waste discharge is discharged.

In the present invention, the first setting value, the second setting value and set point can be set according to those skilled in the art's basic general knowledge and patient's situation.

Above embodiment is only exemplary embodiment of the present invention, is not used in restriction the present invention, and protection scope of the present invention is defined by the claims.Those skilled in the art in essence of the present invention and protection domain, various modifications that the present invention is made or be equal to replacement and also drop in protection scope of the present invention.

Claims (27)

1. a small automatic peritoneal dialysis machine, it is characterized in that: comprise the filling row passage for being connected with human abdominal cavity, the liquid feeding channel that the waste discharge passage of discharging for the liquid that the row's of filling passage is discharged from intraperitoneal is connected with the liquid bag for holding dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with three liquid communication mouths of the first three-way valve and realize the connection under a certain state between each two respective channel in passage at least between two, described filling row passage is also provided with the row's of filling pump, described filling row pump is that two-way pump is to control the row's of filling passage liquid stream direction, described liquid feeding channel is also provided with for heating the heater of dialysis solution and described dialysis solution being pumped into the heat pump of described heater, described liquid feeding channel is also provided with the second three-way valve, described the second three-way valve is between described the first three-way valve and described heat pump, two liquid communication mouths of described the second three-way valve are all connected with described liquid feeding channel, another liquid communication mouth of described the second three-way valve is connected with circulation canal, described circulation canal is connected with described liquid feeding channel.

2. small automatic peritoneal dialysis machine according to claim 1, it is characterized in that: between described at least two respective channel, the connection of a certain state comprises filling with between row's passage and waste discharge passage and is communicated with, fill with between row's passage and liquid feeding channel and be communicated with, between liquid feeding channel and waste discharge passage, be communicated with, or being communicated with between the row's of filling passage and waste discharge passage and three passages of liquid feeding channel.

3. small automatic peritoneal dialysis machine according to claim 1 and 2, it is characterized in that: described the first three-way valve and the second three-way valve include valve body and spool, described spool has at least three liquid flowing channels that communicate with each other and connect, and described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.

4. small automatic peritoneal dialysis machine according to claim 3, it is characterized in that: the valve body of described the first three-way valve and the second three-way valve is the cylindric valve body with inner core, described the first three-way valve and the second three-way valve spool be the inwall that is positioned at described valve body and is close to described valve body, cylindrical spool with respect to described valve body rotation, described spool has three described liquid flowing channels that communicate with each other and connect, three described liquid flowing channels form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T shape or Y shape two arm portions is equal in length with vertical section, described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.

5. small automatic peritoneal dialysis machine according to claim 4, it is characterized in that: described spool is connected with the driving device that drives described Spool rotating, when three described liquid flowing channels are when the projection of horizontal plane forms " Y ", wherein the angle between the projection of two liquid flowing channels is 60 °, and the angle between the projection of another liquid flowing channel and the projection of these two liquid flowing channels is 150 °.

6. according to the small automatic peritoneal dialysis machine described in claim 4 or 5, it is characterized in that: described spool is connected with the driving device that drives described Spool rotating.

7. according to the small automatic peritoneal dialysis machine described in any one in claim 1,2,4 or 5, it is characterized in that: described filling row's pump and/or described heat pump are peristaltic pump or membrane pump.

8. small automatic peritoneal dialysis machine according to claim 6, it is characterized in that: described filling row passage is provided with at least one for detection of the first via pressure transducer of the pressure in described filling row passage, described first via pressure transducer is between abdominal cavity and the row's of filling pump, described liquid feeding channel is provided with at least one for detection of the second road pressure transducer of the pressure in described liquid feeding channel, and described waste discharge passage is provided with at least one for detection of the Third Road pressure transducer of the pressure in described waste discharge passage.

9. small automatic peritoneal dialysis machine according to claim 8, is characterized in that: between described first via pressure transducer and described filling row passage, between described the second road pressure transducer and described liquid feeding channel and be equipped with barrier film device between described Third Road pressure transducer and described waste discharge passage.

10. small automatic peritoneal dialysis machine according to claim 9, it is characterized in that: described filling row passage, liquid feeding channel and/or waste discharge passage are also provided with at least one for detection of the temperature sensor of the temperature of dialysis solution, and/or described filling row's passage, liquid feeding channel and/or waste discharge passage and be located between the temperature sensor of this passage and be provided with barrier film device.

11. small automatic peritoneal dialysis machines according to claim 10, it is characterized in that: described filling row's passage and/or waste discharge passage are provided with at least one flow transducer and/or weight sensor and/or optical pickocff, each passage and be located at flow transducer on this passage and/or weight sensor and/or optical pickocff between be provided with barrier film device.

12. according to the small automatic peritoneal dialysis machine described in any one in claim 9-11, it is characterized in that: described barrier film device comprises housing and the barrier film that is positioned at described housing, and the inner chamber that described barrier film surrounds described housing is partitioned into and the row's of filling passage or liquid feeding channel or waste discharge passage the first chamber being connected and the second chamber being connected with described temperature sensor or described pressure transducer.

13. small automatic peritoneal dialysis machines according to claim 12, is characterized in that: described barrier film is discharged in fluid by the granule without coming off or shot and the good material of biocompatibility is made, as silicone, polyurethane, Biopure^tM, Kraton^tM, Pebax^tMor Santoprene^tMin any material make.

Small automatic peritoneal dialysis machine in 14. according to Claim 8-11 described in any one, it is characterized in that: the liquid conveying system of described peritoneal dialysis also comprises control device, the driving device of described control device and described first via pressure transducer, the second road pressure transducer, Third Road pressure transducer, the first three-way valve, the second three-way valve, the row's of filling pump and heat pump are connected with according to the pressure of the row of filling passage, liquid feeding channel and waste discharge passage or driving device, the row's of filling pump and heat pump that the relation between each channel pressure is controlled the first three-way valve and the second three-way valve.

15. small automatic peritoneal dialysis machines according to claim 14, is characterized in that: described control device is also connected according to the temperature of dialysis solution, to control the first three-way valve and/or the second three-way valve and/or the row's of filling pump and/or heat pump and/or heater with heater with described temperature sensor.

16. small automatic peritoneal dialysis machines according to claim 15, is characterized in that: the flow transducer of described control device and described filling row's passage and/or waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.

17. according to the small automatic peritoneal dialysis machine described in any one or claim 16 or 17 in any one or claim 8-12 in claim 1,2,4 or 5, it is characterized in that: described filling row passage, liquid feeding channel and waste discharge passage consist of the tube for transfusion being tightly connected with described the first three-way valve, the second three-way valve and heater.

18. according to the small automatic peritoneal dialysis machine described in any one or claim 16 or 17 in any one or claim 8-12 in claim 1,2,4 or 5, it is characterized in that: described filling row passage, liquid feeding channel, waste discharge passage, pump line and three-way valve are integrated in a replaceable cartridge.

19. small automatic peritoneal dialysis machines according to claim 18, it is characterized in that: described heater comprises to be located in described replaceable cartridge and to allow the water back that described dialysis solution passes through and be located in described replaceable cartridge for heating plate or the heating film of the dialysis solution transferring heat in described water back, and the inlet of described water back and liquid outlet are all connected with described liquid feeding channel.

The operational approach of the small automatic peritoneal dialysis machine in 20. claim 1-19 described in any one, is characterized in that, comprises following operator scheme:

Circulating-heating pattern: regulating the second three-way valve to make the first section of liquid feeding channel is that the second three-way valve communicates with circulation canal with the section between dialyzate bag, simultaneously the second section of liquid feeding channel is between the section between the second three-way valve and the first three-way valve and the first section and be all cut off between the second section and circulation canal, open heat pump, dialysis solution flows out from dialyzate bag under the effect of heat pump, and flows into heater by rear liquid feeding channel the first section and the circulation canal of flowing into of heater heating;

Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulate the first three-way valve that the row's of filling passage is communicated with the second section of liquid feeding channel, between the second section of waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, be all cut off, regulate the second three-way valve that the second section of liquid feeding channel is communicated with the first section, open the operative orientation that row's pump is filled with in the row's of filling pump setting, the operative orientation of the row's of filling pump makes dialysis solution pass through the first section of liquid feeding channel, the second three-way valve, the second section of liquid feeding channel and the first three-way valve enter the row's of filling passage and flow to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity,

Waste discharge pattern: regulate the first three-way valve to make the row's of filling passage and waste discharge channel connection, the second section of liquid feeding channel and filling are arranged between passage and are cut off between liquid feeding channel and waste discharge passage, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid enter waste discharge passage and flow out arranging passage, the first three-way valve by filling, thereby realize, Intraabdominal waste liquid is excreted.

21. operational approach according to claim 20, it is characterized in that, also comprise overtemperature protection pattern: when liquid feeding channel or while filling with the temperature range that the temperature of dialysis solution in row's passage requires higher than perfusion, close the row's of filling pump and heater, regulate the first three-way valve that liquid feeding channel is connected with waste discharge passage, simultaneously, fill with between row's passage and liquid feeding channel and the row's of filling passage and waste discharge passage between be communicated with and be cut off, regulate the second three-way valve that the first section of liquid feeding channel is communicated with the second section, make overheated dialysis solution liquid self-feeding passage, three-way valve and waste discharge passage are discharged, or during the temperature range that the temperature of dialysis solution requires higher than perfusion in liquid feeding channel or the row's of filling passage, enter waste discharge pattern.

22. operational approach according to claim 20, it is characterized in that, before fill-up mode, also have pipeline is carried out to pre-pattern of rinsing, be specially: regulate the first three-way valve that the second section of liquid feeding channel is all communicated with the row's of filling passage and waste discharge passage, regulate the second three-way valve to make the second section of liquid feeding channel, the first section communicates, dialysis solution is flowed through and is full of liquid feeding channel the first section from dialyzate bag under the effect of heat pump and the row's of filling pump, circulation canal, the second three-way valve, liquid feeding channel the second section, the first three-way valve, the row's of filling passage and waste discharge passage are also discharged from the row's of filling passage and waste discharge passage, the pre-flushing of realization to pipeline.

The operational approach of the small automatic peritoneal dialysis machine described in 23. claim 16, is characterized in that, comprises following operator scheme:

Circulating-heating pattern: regulating the second three-way valve to make the first section of liquid feeding channel is that the second three-way valve communicates with circulation canal with the section between dialyzate bag, the second section of liquid feeding channel is between the section and the first section between the second three-way valve and the first three-way valve simultaneously, and second be all cut off between section and circulation canal, open heat pump, dialysis solution flows out from dialyzate bag under the effect of heat pump, flow into heater by rear the first section and the circulation canal that flows into liquid feeding channel of heater heating, Data Control the second three-way valve that control device transmits according to the temperature sensor of the first section setting of liquid feeding channel, heat pump and heater, during the temperature of dialysis solution requires lower than perfusion in the first section of liquid feeding channel temperature range, continue heating, when in the first section of liquid feeding channel, the temperature of dialysis solution meets the temperature range of perfusion requirement, enter fill-up mode,

Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulate the first three-way valve that the row's of filling passage is communicated with the second section of liquid feeding channel, between the second section of waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, be all cut off, regulate the second three-way valve that the second section of liquid feeding channel is communicated with the first section, open the operative orientation that row's pump is filled with in the row's of filling pump setting, the operative orientation of the row's of filling pump makes dialysis solution pass through the first section of liquid feeding channel, the second three-way valve, the second section of liquid feeding channel and the first three-way valve enter the row's of filling passage and flow to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity, first via pressure transducer detects pressure and/or second road pressure transducer detection filling row's channel pressure of liquid feeding channel and feeds back to control device simultaneously, control device is according to numerical control the first three-way valve of receiving, the second three-way valve, the action of the row's of filling pump and heat pump,

Waste discharge pattern: in the time of need to discharging the waste liquid in human abdominal cavity according to treatment requirement, control device regulates the first three-way valve to make the row's of filling passage and waste discharge channel connection, the second section of liquid feeding channel and filling are arranged between passage and are cut off between liquid feeding channel and waste discharge passage, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid enter waste discharge passage and flow out arranging passage, the first three-way valve by filling, thereby realize, Intraabdominal waste liquid is excreted.

24. operational approach according to claim 23, is characterized in that, when the pressure of liquid feeding channel and/or the row's of filling channel pressure numerical value reach the first setting value, control device is controlled small automatic peritoneal dialysis machine and entered waste discharge pattern.

25. operational approach according to claim 23, it is characterized in that, control device calculates the pressure of liquid feeding channel and the pressure of the row's of the filling passage difference between the two, and when difference reaches the second setting value, control device is controlled small automatic peritoneal dialysis machine and entered waste discharge pattern.

26. according to the method described in any one in claim 23-25, it is characterized in that, also comprise overtemperature protection pattern: when liquid feeding channel or while filling with the temperature range that the temperature of dialysis solution in row's passage requires higher than perfusion, control device cuts out the row's of filling pump and heater according to the data of temperature sensor feedback, regulate the first three-way valve that liquid feeding channel is connected with waste discharge passage and make and cut off between the row's of filling passage and liquid feeding channel and between the row's of filling passage and waste discharge passage, regulate the second three-way valve that the first section of liquid feeding channel is communicated with the second section, close heater simultaneously, make overheated dialysis solution through liquid feeding channel, the second three-way valve, the first three-way valve and waste discharge passage are discharged, or during the temperature range that the temperature of dialysis solution requires higher than perfusion in liquid feeding channel or the row's of filling passage, control device is controlled small automatic peritoneal dialysis machine and is entered waste discharge pattern.

27. according to the method described in any one in claim 23-25, it is characterized in that, control device calculates each perfusion and pours into the amount of the dialysis solution in human abdominal cavity and repeatedly pour into the dialysis solution cumulative amount in human abdominal cavity according to filling with data that flow transducer on row's passage and/or weight sensor and/or optical pickocff transmit, and the data that control device transmits according to the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff can calculate the amount of the waste liquid that each waste discharge discharges and the cumulative amount of the waste liquid of waste discharge discharge repeatedly.

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