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CN103751869A - Fluid conveying system for peritoneal dialysis and operating method therefor - Google Patents

Fluid conveying system for peritoneal dialysis and operating method therefor
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Publication number
CN103751869A
CN103751869ACN201310727308.1ACN201310727308ACN103751869ACN 103751869 ACN103751869 ACN 103751869ACN 201310727308 ACN201310727308 ACN 201310727308ACN 103751869 ACN103751869 ACN 103751869A
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row
passage
filling
liquid
waste discharge
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CN103751869B (en
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王洪利
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Shenzhen Zhili Medical Technology Co ltd
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BEIJING SUNNY MEDICAL TECHNOLOGY Co Ltd
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Abstract

The invention discloses a fluid conveying system for a peritoneal dialysis and an operating method thereof. The fluid conveying system for the peritoneal dialysis comprises an irrigation and drainage channel for communicating with an abdominal cavity of a human body, an exhausting channel for exhausting fluid from the abdominal cavity of the human body by the irrigation and drainage channel, and a fluid supplying channel connected with a fluid-bag for accommodating the dialysis fluid. The irrigation and drainage channel, the exhausting channel and the fluid supplying channel are connected with three fluid circulations of a three-way valve one-to-one correspondingly, wherein the three fluid circulations are in non-uniform distribution, at least two corresponding channels in the three channel partners connected one-to-one correspondingly are connected in a certain condition, and the irrigation and drainage channel is provided with an irrigation and drainage pump which is a two-way pump so as to control the flowing direction in the irrigation and drainage channel. The fluid conveying system solves the technical problems that the existing fluid conveying system has the disadvantages of complex structure, high machining precision requirement and complex operation. The invention provides the fluid conveying system for the peritoneal dialysis and the operating method thereof which have the advantages of simple structure, easiness in machining and convenience in operation.

Description

Liquid conveying system and operational approach thereof for peritoneal dialysis
Technical field
The present invention relates to medical instruments field.Be specially the liquid conveying system and the operational approach thereof that are applicable to peritoneal dialysis.
Background technology
Peritoneal dialysis (Peritoneal Dialysis, english abbreviation PD) is a kind of one of more effective blood purification mode at present, is applicable to carry out after human body injury of kidney the surrogate therapeutic of renal function.Its cardinal principle is that aseptic, the apyrogenic dialysis solution preparing is poured into patient's peritoneal cavity through conduit, utilize the semipermeable membrane characteristic of peritoneum to carry out disperse, infiltration, exchange, and constantly change by abdominal dialysis liquid, reach and remove internal metabolism refuse or toxin, and correct the object of water, electrolyte, acid base imbalance.The operation principle of peritoneal dialysis treatment is to intraperitoneal perfusion dialysis solution and retains after a period of time, the waste liquid after exchange is got rid of external, by perfusion, stop, discharge three important steps and form.Peritoneal dialysis mainly contain two types, continue non-bed peritoneal dialysis (english abbreviation CAPD) and automatization's peritoneal dialysis (english abbreviation APD).CAPD is manually-operated, and change 3-5 every day, conventionally each 2000ml, and APD realizes by peritoneal dialysis machine.Peritoneal dialysis machine or be called cycler (Cycler), patient stays at home and carries out every night conventionally, and a plurality of liquid bags perfusions, the whole loop control process that stops, discharges are completed automatically by machine.APD is the peritoneal dialysis technology of a develop rapidly in recent years, and it not only can help to solve the technical problem of patient's long-term treatment, can also help the patient of many renal failures to reintegrate into society, and is society, family's creation of value.The technological core of APD is liquid supplying way, particularly patent CN1829545B, 200680012708.2 representative for current APD liquid supplying way.But in its fluid administration system design, all adopted numerous special valves or air door to carry out logical combination, to realize the break-make of each pipeline, controlled, cause its pipeline structure design complicated, requirement on machining accuracy is high, thereby cost is very high, and its operation more complicated.
Summary of the invention
The technical problem that the present invention solves is to overcome that the required precision of existing peritoneal dialysis transfusion system complex structure, processing is high, the shortcoming of complicated operation, and a kind of simple in structure, liquid conveying system for peritoneal dialysis of being easy to processing and simple operation is provided.
Liquid conveying system for peritoneal dialysis of the present invention, comprise the filling row passage for being connected with human abdominal cavity, the liquid feeding channel that the waste discharge passage of discharging for the liquid that the row's of filling passage is discharged from intraperitoneal is connected with the liquid bag for holding dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with three liquid communication mouths of three-way valve and realize the connection under a certain state between each two respective channel in passage at least between two, described filling row passage is also provided with the row's of filling pump, described filling row pump is two-way pump, to control the row's of filling passage liquid stream direction.
As preferably, between described at least two respective channel, the connection of a certain state comprises filling with between row's passage and waste discharge passage and is communicated with, fill with between row's passage and liquid feeding channel and be communicated with, between liquid feeding channel and waste discharge passage, be communicated with, or being communicated with between the row's of filling passage and waste discharge passage and three passages of liquid feeding channel.
As preferably, described three-way valve comprises valve body and spool, described spool has at least three liquid flowing channels that communicate with each other and connect, and described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.
As preferably, the valve body of described three-way valve is the cylindric valve body with inner core, the spool of described three-way valve is the inwall that is positioned at described valve body and is close to described valve body, cylindrical spool with respect to described valve body rotation, described spool has three described liquid flowing channels that communicate with each other and connect, three described liquid flowing channels form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T shape or Y shape two arm portions is equal in length with vertical section, described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.
As preferably, when three described liquid flowing channels are when the projection of horizontal plane forms " Y ", wherein the angle between the projection of two liquid flowing channels is 60 °, and the angle between the projection of another liquid flowing channel and the projection of these two liquid flowing channels is 150 °.
As preferably, described spool is connected with the driving device that drives described Spool rotating, and described driving device is electrohydraulic valve actuator machine or mechanical energy rotary apparatus.
As preferably, described filling row pump is peristaltic pump or membrane pump.
As preferably, described filling row passage is provided with at least one for detection of the first via pressure transducer of the pressure in described filling row passage, described first via pressure transducer is between abdominal cavity and the row's of filling pump, described liquid feeding channel is provided with at least one for detection of the second road pressure transducer of the pressure in described liquid feeding channel, and described waste discharge passage is provided with at least one for detection of the Third Road pressure transducer of the pressure in described waste discharge passage.
As preferably, between described first via pressure transducer and described filling row passage, between described the second road pressure transducer and described liquid feeding channel and be equipped with barrier film device between described Third Road pressure transducer and described waste discharge passage.
As preferably, described filling row passage, liquid feeding channel and/or waste discharge passage are also provided with at least one for detection of the temperature sensor of the temperature of dialysis solution, and/or described filling row's passage, liquid feeding channel and/or waste discharge passage and be located between the temperature sensor of this passage and be provided with barrier film device.
As preferably, described filling row passage, waste discharge passage and/or liquid feeding channel are provided with at least one flow transducer and/or weight sensor and/or optical pickocff, each passage and be located at flow transducer on this passage and/or weight sensor and/or optical pickocff between be provided with barrier film device.
As preferably, described barrier film device comprises housing and the barrier film that is positioned at described housing, and the inner chamber that described barrier film surrounds described housing is partitioned into and the row's of filling passage or liquid feeding channel or waste discharge passage the first chamber being connected and the second chamber being connected with described temperature sensor or described pressure transducer.
As preferably, described barrier film is discharged in fluid by the granule without coming off or shot and the good material of biocompatibility is made, as silicone, polyurethane, BiopuretM, KratontM, PebaxtMor SantoprenetMin any material make.
As preferably, the liquid conveying system of described peritoneal dialysis also comprises control device, and described control device is connected to arrange pump according to be related to accessory drive and/or filling between the pressure of the row of filling passage, liquid feeding channel and waste discharge passage or each channel pressure with described first via pressure transducer, the second road pressure transducer, Third Road pressure transducer, driving device and filling row pump.
As preferably, described control device is also connected with described temperature sensor with according to the temperature accessory drive of dialysis solution and/or the row's of filling pump.
As preferably, the flow transducer of described control device and described filling row's passage and waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.
As preferably, described filling row passage, liquid feeding channel and waste discharge passage consist of the tube for transfusion being tightly connected with described three-way valve.
As preferably, described filling row passage, liquid feeding channel, waste discharge passage and three-way valve are integrated in a replaceable cartridge.
The present invention also provides a kind of operational approach of the liquid conveying system for peritoneal dialysis as above, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes the row's of filling passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, cut off, adjust the rotation direction of the row's of filling pump, the rotation direction of the row's of filling pump makes liquid from dialyzate bag, by liquid feeding channel and three-way valve, enter the row's of filling passage under the effect of the row's of filling pump and flows to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity;
Waste discharge pattern: regulating three-way valve makes the row's of filling passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid under the effect of filling with row's pump order by fillings arrange passage, three-way valve enters waste discharge passage outflow, thereby realization excretes Intraabdominal waste liquid.
As preferably, before fill-up mode, also have pipeline is carried out to pre-pattern of rinsing, be specially: regulating three-way valve makes liquid feeding channel be communicated with mutually with the row's of filling passage and waste discharge passage, dialysis solution flows into respectively the row's of filling passage and waste discharge passage and discharges through liquid feeding channel from dialyzate bag, realizes the pre-flushing to pipeline.
The present invention also provides another operational approach for the liquid conveying system of peritoneal dialysis, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes the row's of filling passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, cut off, adjust the rotation direction of the row's of filling pump, the rotation direction of the row's of filling pump makes dialysis solution from dialyzate bag, by liquid feeding channel and three-way valve, enter the row's of filling passage under the effect of the row's of filling pump and flows to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity;
Regulating three-way valve makes the row's of filling passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid under the effect of filling with row's pump order by fillings arrange passage, three-way valve enters waste discharge passage outflow, thereby realization excretes Intraabdominal waste liquid;
In fill-up mode, by first via pressure transducer, detect the pressure of liquid feeding channel and/or detect the row's of filling channel pressure and feed back to control device by the second road pressure transducer, described control device is controlled the action of three-way valve and the row's of filling pump.
As preferably, when the pressure of liquid feeding channel and/or the row's of filling channel pressure numerical value reach the first setting value, the liquid conveying system that control device is controlled for peritoneal dialysis enters waste discharge pattern.
As preferably, control device calculates the pressure of liquid feeding channel and the pressure of the row's of the filling passage difference between the two, and when difference reaches the second setting value, the liquid conveying system that control device is controlled for peritoneal dialysis enters waste discharge pattern.
As preferably, by temperature sensor, detect liquid feeding channel or fill with the temperature of dialysis solution in row's passage and by temperature value transmission control device, when temperature value exceeds set point, control device regulating three-way valve make liquid feeding channel and waste discharge channel connection make to fill with between row's passage and liquid feeding channel simultaneously and the row's of filling passage and waste discharge passage between be not all communicated with, thereby make dialysis solution through liquid feeding channel, three-way valve and the discharge of waste discharge passage; Or when temperature value exceeds set point, the liquid conveying system that control device is controlled for peritoneal dialysis enters waste discharge pattern.
As preferably, control device calculates each perfusion and pours into the amount of the dialysis solution in human abdominal cavity and the perfusion dialysis solution cumulative amount in human abdominal cavity that pours into repeatedly according to filling with data that flow transducer on row's passage and/or weight sensor and/or optical pickocff transmit, and the data that control device transmits according to the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff can calculate amount and the cumulative amount of the waste liquid of waste discharge discharge repeatedly of the waste liquid of each waste discharge discharge.
Liquid conveying system for peritoneal dialysis of the present invention and operational approach thereof compared with prior art, have following beneficial effect:
1, the liquid conveying system for peritoneal dialysis of the present invention only by three-way valve and two-way filling row pump can complete to passage rinse in advance, to patient's intraperitoneal perfusion dialysis solution, from several operations such as the outside drained liquid in patient abdominal cavity, the valve numerous with existing dependence carries out the incompatible technology that realizes the switching of multiple operation of logical groups of break-make and compares, greatly simplify the structure and operating procedure, reduced the requirement to machining accuracy, thereby make its cost, also make easy and simple to handle reliable simultaneously.
2, simple in structure, the reliable operation of its three-way valve, and its spool drives by electrohydraulic valve actuator machine, the spinning movement that can make spool more accurately, reliable.
3, it is filled with row's pump and adopts membrane pump or peristaltic pump, and the inwall that prevents pump contacts with dialysis solution and pollutes dialysis solution.
4, its temperature sensor is all connected with passage by barrier film device with pressure transducer, can prevent that temperature sensor from directly contacting with dialysis solution with pressure transducer and polluting dialysis solution.
5, its control device can be according to the row's of filling pressure of passage, liquid feeding channel and waste discharge passage or the temperature control valve drive motors of the relation between each channel pressure or temperature sensor and the row's of filling pump, make three-way valve automatically adjust to the position needing, make the action of three-way valve timely and reliable, and control start and stop and the direction of rotation that pump is arranged in filling, avoided operator to postpone the danger that operation produces.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of liquid conveying system for peritoneal dialysis of the present invention.
Fig. 2 is three position views of the three-way valve of the liquid conveying system for peritoneal dialysis of the present invention.
Fig. 3 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while carrying out the operation of pre-irrigation channel.
Fig. 4 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while carrying out operating to patient's intraperitoneal perfusion dialysis solution.
Fig. 5 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while carrying out the operation from the outside drained liquid in patient abdominal cavity.
Fig. 6 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while stopping filling with row.
Fig. 7 is the structural representation of the three-way valve of the liquid conveying system for peritoneal dialysis of the present invention, the cross sectional representation that wherein left figure is three-way valve, the structural representation of the longitudinal section that right figure is three-way valve and electrohydraulic valve actuator machine.
Fig. 8 is the schematic diagram of the peristaltic pump of the liquid conveying system for peritoneal dialysis of the present invention.
Fig. 9 is the schematic diagram of the barrier film device of the liquid conveying system for peritoneal dialysis of the present invention.
Figure 10 is the cartridge type schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention.
Reference numeral
1-fills with row's passage, 2-liquid feeding channel, 3-waste discharge passage, 4-three-way valve, 6-fills with row's pump, 7-liquid bag, 10-valve body, 11-spool, 11a-spool rear end, 12-liquid flowing channel, 13-liquid communication mouth, 14-electrohydraulic valve actuator machine, 15-pump head, 16-pump drive motors, 17-roller, 18-bearing, 19-temperature sensor, 20-barrier film device, 21-first via pressure transducer, 22-the second road pressure transducer, 23-Third Road pressure transducer, 24-housing, 25-barrier film, 26-the first chamber, 27-the second chamber, 28-pump line, 29-the first joint, 30-the second joint, 31-control device.
The specific embodiment
The structural representation of Fig. 1 embodiment of liquid conveying system for peritoneal dialysis of the present invention.As shown in Figure 1, liquid conveying system for peritoneal dialysis of the present invention, comprise the row offilling passage 1,liquid feeding channel 2 andwaste discharge passage 3, the row's offilling passage 1 is for being connected with abdominal cavity, liquid feeding channel is for being connected with the liquid bag that holds dialysis solution, andwaste discharge passage 3 is discharged for the liquid that the row's of filling passage is discharged from intraperitoneal.Describedfilling row passage 1,liquid feeding channel 2 are connected with threeliquid communication mouths 13 of three-way valve 4 correspondingly withwaste discharge passage 3, and the realization connection under a certain state between each two respective channel in passage at least between two.Describedfilling row passage 1 is also provided with the row's offilling pump 6, and describedfilling row pump 6 is two-way pump, to control the row's of filling passage liquid stream direction.
In the present invention, " three-way valve 4 " refers to have at least threeliquid communication mouths 13, and can realize following operation: threeliquid communication mouths 13 all communicate with each other, or in threeliquid communication mouths 13 any two are interconnected, anotherliquid communication mouth 13 is closed simultaneously, or threeliquid communication mouths 13 are not all communicated with mutually.Therefore, three-way valve 4 of the present invention can adopt the valve of various concrete forms and structure, as long as realize above function.
In the present invention, between described at least two respective channel, the connection of a certain state comprises filling with between row's passage and waste discharge passage and is communicated with, fill with between row's passage and liquid feeding channel and be communicated with, between liquid feeding channel and waste discharge passage, be communicated with, certainly, fill with between row's passage and waste discharge passage and three passages of liquid feeding channel and also can all be communicated with under a certain state.
In the present invention, " two-way pump " refers to that can realize inlet is switching to the pump that liquid outlet while liquid outlet is switching to inlet,, can realize the pump that flow direction can be switched at positive and negative both direction that is.
In the present invention, as preferred scheme, described three-way valve comprises valve body and spool, described spool has at least three liquid flowing channels that communicate with each other and connect, and described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.As further preferred, the valve body of three-way valve 4 is thecylindric valve body 10 with inner core, spool is the inwall that is positioned at describedvalve body 10 and can be close to describedvalve body 10,cylindrical spool 11 with respect to describedvalve body 10 rotations, as shown in Figure 7, describedspool 11 has three described liquid flowingchannels 12 that communicate with each other and connect, three liquid flowingchannels 12 form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T shape or Y shape two arm portions is equal in length with vertical section, in the present embodiment, three liquid flowingchannels 12 form "T"-shaped in the projection of horizontal plane, wherein two liquid flowingchannels 12 are arranged in same level, anotherliquid flowing channel 12 is arranged on another horizontal plane.Describedvalve body 10 is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the describedliquid communication mouth 13 of the corresponding connection of different conditions.
In other embodiment, three liquid flowing channels also can form " Y " shape (not shown) jointly, as, when three described liquid flowing channels are when the projection of horizontal plane forms " Y ", wherein the angle between the projection of two liquid flowing channels is 60 °, angle between the projection of the projection of another liquid flowing channel and these two liquid flowing channels is 150 °, between certain three liquid flowing channels, also can be other angles.
Certainly, spool also can arrange more liquid flowing channels, and liquid flowing channel can evenly arrange, and also can non-homogeneously arrange, as long as can realize several situations that communicate or disconnect between above-mentioned said three liquid communication mouths.
By above scheme, liquid conveying system for peritoneal dialysis of the present invention at least can be realized following operation: to patient's intraperitoneal perfusion dialysis solution, from the outside drained liquid in patient abdominal cavity, in addition, the liquid conveying system for peritoneal dialysis of the present invention also can be realized passage is rinsed in advance.
Fig. 3 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while carrying out the operation of pre-irrigation channel, as shown in left several the 1st figure in Fig. 3 and Fig. 2, when passage is rinsed in advance, three liquid flowingchannels 12 of three-way valve 4 are relative one by one with threeliquid communication mouths 13, three-way valve 4 is all communicated withliquid feeding channel 2, the row's of fillingpassage 1 andwaste discharge passage 3, and the now row's of fillingpump 6 forward runnings make liquid flow to the left in figure.Dialysis solution enters three-way valve 4 and flows into the row's of fillingpassage 1 andwaste discharge passage 3 by three-way valve 4 throughliquid feeding channel 2, and the flow direction of dialysis solution is as shown in the arrow in Fig. 3.Dialysis solution can stop pre-flushing operation after being full of the row's of fillingpassage 1 andwaste discharge passage 3, and this operation can be driven the air in each passage away and passage is cleaned.
Fig. 4 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while carrying out operating to patient's intraperitoneal perfusion dialysis solution, as shown in left several the 2nd figure in Fig. 4 and Fig. 2, during to patient's intraperitoneal perfusion dialysis solution, two liquid flowingchannels 12 of three-way valve 4 are aimed at twoliquid communication mouths 13 that are connected with fillingrow passage 1 withliquid feeding channel 2 respectivelyliquid feeding channel 2 and the row's of fillingpassage 1 are connected by three-way valve 4, anotherliquid flowing channel 12 is closed, the now row's of fillingpump 6 forward runnings make liquid flow to the left in figure, that is, flow into the intraperitoneal of human body.Dialysis solution enters three-way valve 4 and flows into the row's of fillingpassage 1 by three-way valve 4 throughliquid feeding channel 2, pumps into the intraperitoneal of human body through the row's of fillingpump 6, and the flow direction of dialysis solution is as shown in the arrow in Fig. 4.
Fig. 5 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while carrying out the operation from the outside drained liquid in patient abdominal cavity, as shown in left several the 3rd figure in Fig. 5 and Fig. 2, two liquid flowingchannels 12 of three-way valve 4 are aimed at twoliquid communication mouths 13 that are connected withwaste discharge passage 3 with fillingrow passage 1 respectively the row's of fillingpassage 1 andwaste discharge passage 3 are connected by three-way valve 4, and anotherliquid flowing channel 12 is closed.Fill with row'spump 6 antiports, liquid in abdominal cavity is flowed out and enter the row's of fillingpassage 1, and then enterwaste discharge passage 3 and discharge, the flow direction of liquid as shown in Figure 5.
Fig. 6 is the schematic diagram of the liquid conveying system for peritoneal dialysis of the present invention while stopping filling with row, as shown in Figure 6, the row's of fillingpump 6 is out of service, three liquid flowingchannels 12 of three-way valve 4 all seal, as shown in left several the 4th figure in Fig. 2, now the row's of fillingpassage 1,liquid feeding channel 2 andwaste discharge passage 3 are not communicated with mutually, can prevent that liquid from flowing out.
Liquid conveying system for peritoneal dialysis of the present invention only can complete above-mentioned all operations by three-way valve and two-way filling row pump, compare with existing dependence technology, greatly simplify the structure, reduced the requirement to machining accuracy, thereby make its cost, also make easy and simple to handle reliable simultaneously.
As of the present invention preferably, spoolrear end 11a connecting drive device, the spool of driving device and " Y " shape "T"-shaped projecting into of horizontal plane applicable to liquid flowing channel.Driving device is preferably electrohydraulicvalve actuator machine 14, as shown in Figure 7, left figure is the cross sectional representation of three-way valve 4, right figure is the longitudinal section of three-way valve 4 and the schematic diagram of electrohydraulicvalve actuator machine 14, can pass through operatingvalve drive motors 14, makespool 11 rotation to the position needing carrying out rinsing in advance accordingly, to intraperitoneal perfusion dialysis solution, from abdominal cavity drained liquid or make the operations such as the row of filling stops.Certainly the driving device that driving device also can adopt other actuatable valve cores rotations as, rotary handle, or other mechanisms that rotate by mechanical energy.
As of the present invention preferred, described fillingrow pump 6 is peristaltic pump or membrane pump, and dialysis solution can not contacted with the inwall of pump, prevents other materials to bring in human body human body is worked the mischief.Wriggling pump structure as shown in Figure 8, left figure is the front view of peristaltic pump, right figure is the assembly structure figure of peristaltic pump, and peristaltic pump comprisespump head 15,flexible pump line 28 and thepump drive motors 16 that drivespump head 15 to rotate, and pumphead 15 is provided with a plurality of rollers that are evenly arranged 17.Pump head 15 is also provided with pump head bearing 18, and is connected withpump drive motors 16 by bearing 18.
Well-known in this area, it is directly related that the efficiency of peritoneal dialysis and liquid rest on the intraperitoneal time, and the discharge stage can limit with regard to its persistent period, and the function that this persistent period is drainage rate.Conventionally the initial discharge process of CAPD is 200ml/min left and right, and along with patient's intra-abdominal pressure reduces, this drainage rate also decreases, and has also just directly affected whole dialysis time.Therefore,, in the design of APD, how dynamic adjustments, for the pump speed of the row of filling, seems particularly important to improve dialytic efficiency.
As of the present invention preferred, the present invention has given a solution: betweenpump head 15 andpump line 28, be designed to two kinds of contact conditions: extrusion pump tubulose state and non-extrusion pump tubulose state.Particularly, by therelated pump head 15 of pump head bearing 18, move up and down to realize the conversion of two kinds of states, wherein also comprised thatpump drive motors 16 is rotated and given kinetic energy by the gear inpump head 15.
When under extrusion pump tubulose state, duringpump head 15 rotation, theflexible pump line 28 ofroller 17 extruding, the direction of the liquid runs down extruding inflexible pump line 28 is flowed, now can set by the requirement of anticipation the flow velocity of the row's of fillingpump 6, now, also can be by adopting high-precision numeric type, flow type peristaltic pump to calculate each circumfusion amount and the accumulative total groundwater increment of dialysis solution.
Under non-extrusion pump tubulose state, 15 pairs of pump lines ofpump head 28 are not controlled, guarantee to start to rely on Intraabdominal pressure to realize the excretion naturally of waste liquid in discharge process, and when intra-abdominal pressure reduction can not continue nature excretion, change again pump line into squeezed state, now also by the pressure differential between a plurality of pressure transducers, carry out the speed that dynamic adjustments is filled with row'spump 6, can shorten the time of discharge process on the one hand, guarantee the groundwater increment dischargeable capacity of next circulation, to improve dialytic efficiency, also to guarantee that on the other hand drainage rate is the tolerance interval of patient safety.After this, also will the effect of described pressure transducer be described.
Certainly, these are only preferred scheme, also can adopt other to make liquid and the discontiguous pump of pump, and can meet the operation requirements of the required perfusion of peritoneal dialysis, reservation, discharge process.
As preferably, described fillingrow passage 1,liquid feeding channel 2 and/orwaste discharge passage 3 are also provided with at least one for detection of thetemperature sensor 19 of the temperature of dialysis solution.In the present embodiment, describedliquid feeding channel 2 and the row's of fillingpassage 1 are equipped with thetemperature sensor 19 for detection of the temperature of dialysis solution.Waste discharge passage 3 also can arrange not set temperaturesensor.Temperature sensor 19 is more reliable than the temperature of human perception dialysis solution, can detect more accurately, more in time the temperature of dialysis solution, prevents that the dialysis solution that is unsuitable for body temperature from flowing into human body.Described temperature sensor and be provided with between the passage of this temperature sensor and be provided withbarrier film device 20, can prevent thattemperature sensor 19 from contacting with dialysis solution and polluting dialysis solution.Certainly, filling with row's passage also can set temperature sensor, and the row's of filling passage is also provided with barrier film device with being located between the temperature sensor of the row's of filling passage.
Well-known in this area, in peritoneal dialysis process, the pressure measxurement of the row of filling is a very important factor with control, if particularly link pressure increase on patient's pipeline, exceeds warning and limits, and may produce serious injury to patient.As preferably, described fillingrow passage 1 is provided with at least one for detection of the first viapressure transducer 21 of the pressure in described fillingrow passage 1, described first viapressure transducer 21 is between abdominal cavity and the row's of fillingpump 6, describedliquid feeding channel 2 is provided with at least one for detection of the secondroad pressure transducer 22 of the pressure in describedliquid feeding channel 2, and describedwaste discharge passage 3 is provided with at least one for detection of the described ThirdRoad pressure transducer 23 for the pressure in waste discharge road.Between described first viapressure transducer 21 and described fillingrow passage 1, between described the secondroad pressure transducer 22 and describedliquid feeding channel 2 and be equipped withbarrier film device 20 between described ThirdRoad pressure transducer 23 and describedwaste discharge passage 3, can prevent that pressure transducer from directly contacting with liquid.
Described fillingrow passage 1,waste discharge passage 3 and/orliquid feeding channel 2 are provided with at least one flow transducer and/or weight sensor and/or optical pickocff.That is, the row's of fillingpassage 1 andwaste discharge passage 3 are equipped with a flow transducer and/or weight sensor and/or optical pickocff, andliquid feeding channel 2 can arrange the sensor, also can not arrange.
Describedbarrier film device 20 compriseshousing 24 and is positioned at thebarrier film 25 of describedhousing 24, and as shown in Figure 9, housing can be the cylindricality in the left figure of figure, can also be spherical as in right figure.The inner chamber that describedbarrier film 25 surrounds describedhousing 24 is partitioned into and the row's of fillingpassage 1 orliquid feeding channel 2 orwaste discharge passage 3 thefirst chamber 26 being connected and thesecond chamber 27 being connected with describedtemperature sensor 19 or pressure transducer.The first chamber of barrier film device has for having the second joint 30 for being connected with temperature sensor or pressure transducer with channel attached the first joint 29, the secondchambeies.Temperature sensor 19 can be determined by detecting the temperature of thebarrier film 25 directly contacting with dialysis solution the temperature of dialysis solution.Pressure transducer can change the pressure of determining liquid by air pressure or the pressure detecting in the deformation ofbarrier film 25 or thesecond chamber 27 thatbarrier film 25 deformation cause.
As preferably,barrier film 25 is biocompatible, and for example, by welding, clamping, gluing, laser or hot melt,barrier film 25 is easily sealed in the liquid conveying system for peritoneal dialysis.In addition,barrier film 25 should be by without the granule that come off or shot is discharged in fluid and the good material of biocompatibility is made, as for example by silicone, polyurethane, BiopuretM, KratontM, PebaxtMor SantoprenetMin any one or several materials make.This particle release is due to mechanical stress or because self moving of causing of material itself causes.In addition,barrier film 25 must be soft and resilient, correctly to realize valve and/or pumping function.
In addition, for the liquid conveying system of peritoneal dialysis, also comprise one or several flow-sensint unit (not shown), the location optimization of flow-sensint unit is entrance or the outlet near the row's of filling pump.The type of flow-sensint unit can be selected as required.For example, can be mechanical, for example turbine flowmeter, can be quality formula, calorifics effusion meter for example, can also be electronics or magnetic.
As preferably, the described liquid conveying system for peritoneal dialysis also comprisescontrol device 31, as shown in figure 10, describedcontrol device 31 is connected with the pressure of each passage of Real-Time Monitoring and adjusts in time valve electrohydraulicvalve actuator machine 14 and the row's of fillingpump 6 according to the pressure of the row of fillingpassage 1,liquid feeding channel 2 andwaste discharge passage 3 or the relation between each channel pressure with described first viapressure transducer 21, the secondroad pressure transducer 22, ThirdRoad pressure transducer 23, electrohydraulicvalve actuator machine 14 and the row's of filling pump 6.In the present embodiment, described control device is also connected to arrangepump 6 according to the temperature controlvalve drive motors 14 of dialysis solution and filling with described temperature sensor 19.Above scheme has realized the automatic control of the liquid conveying system of peritoneal dialysis, makes the action of three-way valve 4 timely and reliable, has avoided operator to forget or has delayed the problem that operation produces.
The present invention designs San road pressure transducer and control device has following effect: the first, real-time dynamic monitoring injection pressure and Intraabdominal pressure and between the pressure differential liquid stream that prevents from pouring into abdominal cavity cause intraperitoneal to produce too high pressure to guarantee patient's safety.Second, as previously mentioned, can utilize above-mentioned three road pressure transducers independently pressure value variation or the variation of the pressure difference value between it, realize the turned on or off that dynamic adjustments is filled with the flow velocity of row'spump 6 and controlled in real time three-way valve 4, wherein also comprised when patient is with respect to the position of peritoneal dialysis machine (APD) and the change in location of dialyzate bag, and cause pouring into intraperitoneal liquid, miscarried while giving birth to too high pressure by regulating flow velocity to carry out feedback control.The 3rd, in the discharge process of peritoneal dialysis, can utilize the variation of pressure reduction between pipeline inner pressure numerical value and pipeline, set up the mathematical model of a dynamic correlation with output, to guarantee that perfusion intraperitoneal liquid stream is all the time in a safe pressure threshold range, or guarantee that the Intraabdominal accumulative total of perfusion fluid flow is all the time in a safe traffic threshold range.
As preferably, the flow transducer of described control device and described filling row passage, liquid feeding channel and/or waste discharge channel setting and/or weight sensor and/or optical pickocff are connected.
Liquid conveying system for peritoneal dialysis of the present invention can be arranged to pipeline type,, described fillingrow passage 1,liquid feeding channel 2 andwaste discharge passage 3 consist of the tube for transfusion being tightly connected with described three-way valve, and be tightly connected with three-way valve 4, the row's of fillingpump 6, temperature sensor and pressure transducer, as shown in Figure 1.Wherein, described fillingrow passage 1,liquid feeding channel 2,waste discharge passage 3 and three-way valve 4 are made by medical-grade plastics material.
Liquid conveying system for peritoneal dialysis of the present invention can also integratedly be set to a replaceable cartridge,, described fillingrow passage 1,liquid feeding channel 2,waste discharge passage 3, pump line, three-way valve are integrated in a replaceable cartridge, as shown in figure 10, during use, replaceable cartridge is matched with other devices.Described barrier film device is according to its above-mentioned design principle, also can be incorporated into or design in cartridge, the temperature of dialysis solution can be directly measured in temperature sensor bybarrier film 25, pressure transducer can be distinguished directly by the pressure inbarrier film 25 measurement fillingrow passages 1,liquid feeding channel 2,waste discharge passage 3 and mutual pressure reduction.According to pressure differential pressure, change and cartridge fixed volume, the present invention also can accurately calculate the groundwater increment of dialysis solution, output, and effectively controls the pressure in patient abdominal cavity.
The present invention also provides a kind of operational approach of the liquid conveying system for peritoneal dialysis, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes the row's of filling passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, cut off, adjust the rotation direction of the row's of filling pump, the rotation direction of the row's of filling pump makes liquid from dialyzate bag, by liquid feeding channel and three-way valve, enter the row's of filling passage under the effect of the row's of filling pump and flows to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity;
Waste discharge pattern: regulating three-way valve makes the row's of filling passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid under the effect of filling with row's pump order by fillings arrange passage, three-way valve enters waste discharge passage outflow, thereby realization excretes Intraabdominal waste liquid.
As preferably, before fill-up mode, also have pipeline is carried out to pre-pattern of rinsing, be specially: close the row's of filling pump, regulating three-way valve makes liquid feeding channel be communicated with mutually with the row's of filling passage and waste discharge passage, dialysis solution flows into respectively the row's of filling passage and waste discharge passage and discharges through liquid feeding channel from dialyzate bag, realizes the pre-flushing to pipeline.
The present invention also provides the operational approach of the another kind of liquid conveying system for peritoneal dialysis, in this kind of peritoneal dialysis treatment device, has control device, and control device at least can be controlled the action of three-way valve and the row's of filling pump, comprises following operator scheme:
Fill-up mode: be communicated with the row's of filling passage and human abdominal cavity, regulating three-way valve makes the row's of filling passage communicate with liquid feeding channel, between waste discharge passage and liquid feeding channel and between waste discharge passage and the row's of filling passage, cut off, adjust the rotation direction of the row's of filling pump, the rotation direction of the row's of filling pump makes dialysis solution from dialyzate bag, by liquid feeding channel and three-way valve, enter the row's of filling passage under the effect of the row's of filling pump and flows to the abdominal cavity of human body, thereby realize, dialysis solution is injected in human abdominal cavity;
Waste discharge pattern: regulating three-way valve makes the row's of filling passage and waste discharge channel connection, liquid feeding channel and filling are arranged between passage and between liquid feeding channel and waste discharge passage and are all cut off, make the rotation direction of the row's of filling pump contrary with the operative orientation under fill-up mode, make Intraabdominal liquid under the effect of filling with row's pump order by fillings arrange passage, three-way valve enters waste discharge passage outflow, thereby realization excretes Intraabdominal waste liquid;
In fill-up mode, can detect the pressure of liquid feeding channel and/or detect the row's of filling channel pressure and feed back to control device by the second road pressure transducer by first via pressure transducer, when pressure value reaches the first setting value, the liquid conveying system that control device is controlled for peritoneal dialysis enters waste discharge pattern.
Or in fill-up mode, by first via pressure transducer, detect the pressure of liquid feeding channel and pressure value is sent to control device, by the second road pressure transducer, detect the pressure of the row's of filling passage and pressure value is sent to control device, control device calculates the pressure of liquid feeding channel and the pressure of the row's of the filling passage difference between the two, when difference reaches the second setting value, the liquid conveying system that control device control device is controlled for peritoneal dialysis enters waste discharge pattern.
In addition, by temperature sensor, detect liquid feeding channel or fill with the temperature of dialysis solution in row's passage and by temperature value transmission control device, when temperature value exceeds set point, control device regulating three-way valve make liquid feeding channel and waste discharge channel connection make to fill with between row's passage and liquid feeding channel simultaneously and the row's of filling passage and waste discharge passage between be not all communicated with, thereby make dialysis solution through liquid feeding channel, three-way valve and the discharge of waste discharge passage; Or when temperature value exceeds set point, the liquid conveying system that control device is controlled for peritoneal dialysis enters waste discharge pattern.
As preferably, the data that control device can transmit according to the flow transducer on the row's of filling passage and/or weight sensor and/or optical pickocff calculate amount and the dialysis solution cumulative amount of dialysis perfusion repeatedly of the dialysis solution of each dialysis perfusion.Also can the amount of the dialysis solution of each perfusion be set by control device is set, when groundwater increment reaches the numerical value of setting, control device stops perfusion, and according to the standby that need to maintain a period of time of medical treatment.Stand-by time is control device regulating three-way valve and the row's of filling pump later, makes the whole liquid conveying system for peritoneal dialysis forward waste discharge pattern to from fill-up mode.
Control device calculates each perfusion and pours into the amount of the dialysis solution in human abdominal cavity and the perfusion dialysis solution cumulative amount in human abdominal cavity that pours into repeatedly according to filling with data that flow transducer on row's passage and/or weight sensor and/or optical pickocff transmit, and the data that control device transmits according to the flow transducer on waste discharge passage and/or weight sensor and/or optical pickocff can calculate amount and the cumulative amount of the waste liquid of waste discharge discharge repeatedly of the waste liquid of each waste discharge discharge.Certainly, the data that control device also can transmit according to the flow transducer on liquid feeding channel and/or weight sensor and/or optical pickocff calculate the amount of the dialysis solution that each perfusion supplies and the dialysis solution cumulative amount that repeatedly perfusion is supplied.
Under ideal case, liquid feeding channel, the row's of filling passage and waste discharge passage are not all communicated with mutually, and close the row's of filling pump.
In the present invention, the setting of the first setting value, the second setting value and stand-by time can be set according to those skilled in the art's basic general knowledge and patient's situation, and setting value also can according to circumstances regulate accordingly.
Above embodiment is only exemplary embodiment of the present invention, is not used in restriction the present invention, and protection scope of the present invention is defined by the claims.Those skilled in the art in essence of the present invention and protection domain, various modifications that the present invention is made or be equal to replacement and also drop in protection scope of the present invention.

Claims (25)

1. the liquid conveying system for peritoneal dialysis, it is characterized in that: comprise the filling row passage for being connected with human abdominal cavity, the liquid feeding channel that the waste discharge passage of discharging for the liquid that the row's of filling passage is discharged from intraperitoneal is connected with the liquid bag for holding dialysis solution, described filling row passage, waste discharge passage and liquid feeding channel are connected correspondingly with three liquid communication mouths of three-way valve and realize the connection under a certain state between each two respective channel in passage at least between two, described filling row passage is also provided with the row's of filling pump, described filling row pump is two-way pump, to control the row's of filling passage liquid stream direction.
4. the liquid conveying system for peritoneal dialysis according to claim 3, it is characterized in that: the valve body of described three-way valve is the cylindric valve body with inner core, the spool of described three-way valve is the inwall that is positioned at described valve body and is close to described valve body, cylindrical spool with respect to described valve body rotation, described spool has three described liquid flowing channels that communicate with each other and connect, three described liquid flowing channels form "T"-shaped or " Y " shape in the projection of horizontal plane, and the length of T shape or Y shape two arm portions is equal in length with vertical section, described valve body is provided with in three liquid flowing channels between two with described liquid flowing channel each two liquid flowing channels at the described liquid communication mouth of the corresponding connection of different conditions.
24. according to the method described in any one in claim 21-23, it is characterized in that, by temperature sensor, detect liquid feeding channel or fill with the temperature of dialysis solution in row's passage and by temperature value transmission control device, when temperature value exceeds set point, control device regulating three-way valve make liquid feeding channel and waste discharge channel connection make to fill with between row's passage and liquid feeding channel simultaneously and the row's of filling passage and waste discharge passage between be not all communicated with, thereby make dialysis solution through liquid feeding channel, three-way valve and the discharge of waste discharge passage; Or when temperature value exceeds set point, the liquid conveying system that control device is controlled for peritoneal dialysis enters waste discharge pattern.
CN201310727308.1A2013-05-062013-12-25For liquid conveying system and the operational approach thereof of peritoneal dialysisActiveCN103751869B (en)

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CN104721920A (en)*2015-03-262015-06-24江苏阳普医疗科技有限公司Multi-speed regulation device of infusion pump and speed regulation method thereof
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CN103751871B (en)2016-06-29
CN103751870A (en)2014-04-30

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