Summary of the invention
The goal of the invention of the present invention is, it is provided that a kind of compositions substituting tobacco shred and preparation method thereof, has both adapted to inhaleThe demand of cigarette person, can play again the effect of lung heat clearing, sore-throat relieving, cough-relieving, toxin expelling, smoking cessation, and clinical efficacy is notable.
The technical scheme is that
In case of no particular description, the ratio being previously mentioned in the present invention is all part by weight.
A kind of compositions substituting tobacco shred, it includes the following component of weight ratio: cigarette filament 10～100 parts, be sprayed atPure Chinese medicine extraction concentrated solution 1 on described cigarette filament～10 parts and spice 0.5～1 part, wherein, described cigarette filament include asThe component of lower weight ratio: yunnan puer tea 30～40 parts, Flos Rosae Rugosae 20～30 parts, Thamnolia vermicularis (Ach.) Asa-hina 20～30 parts, LINGDANCAO 20～30 parts,Stigma Croci 15～25 parts, Folium Ginkgo 15～25 parts.
Described pure Chinese medicine extraction concentrated solution includes the extract of following ratio of weight and number component: Radix Rubiae 10～20 parts, gold silverSpend 20～30 parts, Flos Chrysanthemi 15～25 parts, Herba Taraxaci 20～30 parts, lavandula angustifolia 15～25 parts, Folium Nelumbinis 15～25 parts, Cacumen Platycladi 10～20 parts, Semen Oroxyli 10～20 parts, CitrusaurantiumL.Var.amara Engl. 15～25 parts, Herba Lophatheri 15～25 parts, Herba Pogostemonis 10～20 parts.
Described pure Chinese medicine extraction concentrated solution can also include the extract of following ratio of weight and number component: Radix Glehniae 10～20Part, Aloe 10～20 parts, Fructus Perillae 15～25 parts, Radix Rhodiolae 15～25 parts, Cortex Magnoliae Officinalis 15～25 parts, Fructus Fici 10～20 parts, the Radix Astragali15～25 parts, Radix Notoginseng 10～20 parts, Radix Angelicae Sinensis 10～20 parts, Radix Glycyrrhizae 15～25 parts, Flos Caryophylli 15～25 parts, Radix Platycodonis 20～30 parts, Pueraria lobotaRoot 10～20 parts, Radix Panacis Quinquefolii 20～30 parts, Bulbus Lilii 20～30 parts, Fructus Momordicae 20～30 parts, Poria 10～20 parts, Semen Sterculiae Lychnophorae 10～20 parts, pericarpium citri grandis 15～25 parts, Bulbus Fritillariae Cirrhosae 10～20 parts, Rhizoma Polygonati Odorati 15～25 parts, Semen Sinapis 15～25 parts, Rhizoma Imperatae 10～20Part, Bulbus Allii Macrostemonis 15～25 parts, Radix Ophiopogonis 10～20 parts, Rhizoma Chuanxiong 10～20 parts, Semen Coicis 15～25 parts, Semen Armeniacae Amarum 10～20 parts, Pericarpium Citri Reticulatae 15～30 parts, Lignum Aquilariae Resinatum 15～25 parts, Ganoderma 10～20 parts.
Preferably, described pure Chinese medicine extraction concentrated solution can also include extracting solution A and B mixed in any proportion as follows；
Extracting solution A: include the extracting solution of following ratio of weight and number component, Radix Rubiae 10～20 parts, Flos Lonicerae 20～30 parts, tributeChrysanthemum 15～25 parts, Herba Taraxaci 20～30 parts, lavandula angustifolia 15～25 parts, Folium Nelumbinis 15～25 parts, Cacumen Platycladi 10～20 parts, Semen Oroxyli 10～20 parts, CitrusaurantiumL.Var.amara Engl. 15～25 parts, Herba Lophatheri 15～25 parts, Herba Pogostemonis 10～20 parts；
Extracting solution B: include the extract of following ratio of weight and number component, Radix Glehniae 10～20 parts, Aloe 10～20 parts, Soviet UnionSon 15～25 parts, Radix Rhodiolae 15～25 parts, Cortex Magnoliae Officinalis 15～25 parts, Fructus Fici 10～20 parts, the Radix Astragali 15～25 parts, Radix Notoginseng 10～20Part, Radix Angelicae Sinensis 10～20 parts, Radix Glycyrrhizae 15～25 parts, Flos Caryophylli 15～25 parts, Radix Platycodonis 20～30 parts, Radix Puerariae 10～20 parts, Radix Panacis Quinquefolii 20～30 parts, Bulbus Lilii 20～30 parts, Fructus Momordicae 20～30 parts, Poria 10～20 parts, Semen Sterculiae Lychnophorae 10～20 parts, pericarpium citri grandis 15～25Part, Bulbus Fritillariae Cirrhosae 10～20 parts, Rhizoma Polygonati Odorati 15～25 parts, Semen Sinapis 15～25 parts, Rhizoma Imperatae 10～20 parts, Bulbus Allii Macrostemonis 15～25 parts, wheatWinter 10～20 parts, Rhizoma Chuanxiong 10～20 parts, Semen Coicis 15～25 parts, Semen Armeniacae Amarum 10～20 parts, Pericarpium Citri Reticulatae 15～30 parts, Lignum Aquilariae Resinatum 15～25Part, Ganoderma 10～20 parts.
Further, described spice can also include the extract of mentha leave.
The preparation method of a kind of compositions substituting tobacco shred, comprises the steps:
(1) cigarette filament is prepared, by the component ethanol mix homogeneously of aforementioned cigarette filament, the moistening shape of stirring, keep roomBetween temperature 20～30 degree, sealed fermenting 3 days, dry, then with tabacco cutter, said mixture cut into about 5mm cigarette filament,Go forward side by side circulation of qi promoting fluidized drying.
(2) prepare pure Chinese medicine extraction concentrated solution, described pure Chinese medicine refinement concentrated solution is uniformly sprayed onto described first step instituteCigarette filament on, low temperature, be dried;
(3) prepare spice, described spice is sprayed onto on the cigarette filament of second step gained.
Preferably, described step (2) comprises the steps, weighs Radix Rubiae 10～20 parts, gold silver the most respectivelySpend 20～30 parts, Flos Chrysanthemi 15～25 parts, Herba Taraxaci 20～30 parts, lavandula angustifolia 15～25 parts, Folium Nelumbinis 15～25 parts, Cacumen Platycladi 10～20 parts, Semen Oroxyli 10～20 parts, CitrusaurantiumL.Var.amara Engl. 15～25 parts, Herba Lophatheri 15～25 parts, Herba Pogostemonis 10～20 parts, mix homogeneously, addIn ethanol to 50%～80%, it is heated to reflux 40min for the first time, filters；Second time is heated to reflux 20min, filters, and merges filterLiquid；It is concentrated to the pure Chinese medicine extraction concentrated solution of density 1.20～1.30.
Preferably, described step (2) also comprises the steps, weigh the most respectively Radix Glehniae 10～20 parts,Aloe 10～20 parts, Fructus Perillae 15～25 parts, Radix Rhodiolae 15～25 parts, Cortex Magnoliae Officinalis 15～25 parts, Fructus Fici 10～20 parts, the Radix Astragali 15～25 parts, Radix Notoginseng 10～20 parts, Radix Angelicae Sinensis 10～20 parts, Radix Glycyrrhizae 15～25 parts, Flos Caryophylli 15～25 parts, Radix Platycodonis 20～30 parts, Radix Puerariae 10～20 parts, Radix Panacis Quinquefolii 20～30 parts, Bulbus Lilii 20～30 parts, Fructus Momordicae 20～30 parts, Poria 10～20 parts, Semen Sterculiae Lychnophorae 10～20Part, pericarpium citri grandis 15～25 parts, Bulbus Fritillariae Cirrhosae 10～20 parts, Rhizoma Polygonati Odorati 15～25 parts, Semen Sinapis 15～25 parts, Rhizoma Imperatae 10～20 parts,Bulbus Allii Macrostemonis 15～25 parts, Radix Ophiopogonis 10～20 parts, Rhizoma Chuanxiong 10～20 parts, Semen Coicis 15～25 parts, Semen Armeniacae Amarum 10～20 parts, Pericarpium Citri Reticulatae 15～30Part, Lignum Aquilariae Resinatum 15～25 parts, Ganoderma 10～20 parts of mix homogeneously, pulverize, cross 50 mesh sieves, be placed in the extraction kettle of 1L, adds extraction altogetherTake agent ethanol, if extracting pressure 15～45Mpa, extraction temperature 30～50 DEG C, separating still pressure 10～30Mpa, separation temperature 30～60 DEG C, CO2 flow 1L～3L/min, extraction time 1.0h～3.0h.Filter, obtain extract.
Further, described step (2) can also comprise the steps, the filtrate obtained by the step of both of the aforesaid is pressedMixing according to arbitrary proportion, the pure Chinese medicine being concentrated to density 1.20～1.30 refines concentrated solution.
Preferably, described step (3) includes, weighs mentha leave by ratio of weight and the number of copies, pulverizes, and takes powder and loads extraction kettle,Being 6.0～9.0MPa in extracting pressure, extraction temperature is 30 DEG C～55, under conditions of CO2 flow is 1L～3L/min, usesCO2 supercritical extraction 1.0～2.0h, collects Oleum menthae, with anhydrous sodium sulfate dehydration, filter paper, filtration, uses 95% ethanol dilution.
Preferable described step (3) includes, weighs Golden jujube by ratio of weight and the number of copies, adds 70% alcohol heating reflux 2h, mistakeFilter.
The invention also discloses the application as tobacco shred substitute of the described cigarette filament.
Further, the invention also discloses the sprinkling interpolation as tobacco shred substitute of the described pure Chinese medicine extraction concentrated solutionThe application of agent.
Further, the invention also discloses extract the answering as the spice on tobacco shred substitute of described mentha leaveWith.
The beneficial effects of the present invention is: the present invention use major ingredient yunnan puer tea be warming the stomach, blood fat reducing, anti-cancer, anticancer,The holy product fostered the spirit of nobility.Folium camelliae assamicae containing caffeine, its be a kind of xanthine alkaloid compound, be a kind of central nervous excitation agent, meetingStimulate the central nervous system of brain, extend brain clear-headed time and relieving fatigue.Tea polyphenols in tea, tannic acid, dimension are rawElement has absorption complexing to nicotine, such that it is able in purged body the content of nicotine and play the effect of smoking cessation.There is researchShowing, in tea, ingredient can also make flue gas sweet, fine and smooth soft, covers miscellaneous QI, reduces stimulation, easy firing, does not stops working.So can be as the substitute of Nicotiana tabacum L..
The present invention can also apply to the pulmonary disease that the many factors such as smoking cause, and long smoker is crossed in most smoking, clinicalExpectorant is few, expectoration is not well to show themselves in that cough, puckery and difficulty goes out, dry mouth and throat or dyspnea.Chinese medicine composition of the present invention mainly has ZhejiangBulbus Fritillariae Uninbracteatae, Bulbus Lilii, Rhizoma Imperatae, Radix Ophiopogonis, Rhizoma Phragmitis, Fructus Momordicae have the merit of removing heat-phlegm, nourishing the lung to arrest cough, Dingchuan, compatibility Semen Sterculiae Lychnophorae, woodizationButterfly, CitrusaurantiumL.Var.amara Engl., Rhizoma Polygonati Odorati, Herba Lophatheri, Rhizoma Imperatae, Bulbus Allii Macrostemonis, Cortex Magnoliae Officinalis, Folium Eriobotryae enhance clear and rich reduce phlegm, cough-relieving, the power moisturized.(volume in " Records of Tradition Chinese and Western Medicine in Combination ") expectorant is given birth to because of insufficiency of the spleen, is coagulated because of the stagnation of QI, therefore with Poria, Semen Coicis spleen invigorating eliminating dampness by diuresis, with Du ShengThe source of expectorant；Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Lignum Aquilariae Resinatum, Fructus Fici activating QI to eliminate phlegm, make gas disappear along expectorant；Again with Radix Platycodonis, Semen Armeniacae Amarum, Fructus Perillae a surname's profit lungGas, preventing phlegm from forming and stopping coughing, make lung gold a surname's fall have the right, the conjunction side of forming, clear and rich sharp with a surname and use, based on lung heat clearing, and moisten and do not hinder and reduce phlegm,Reduce phlegm and not impairment of body fluid, make lung obtain clear and rich and dry phlegm from changing, a surname's fall have the right and cough with dyspnea from flat.
Using method of the present invention is as follows:
1, i.e. utilize the principle of " herbal fumigation therapy ", by the tobacco shred substitute composition of the present invention of burning, produce flue gasVia oral cavity, respiratory tract, arrival lung tissue, medicine ion is directly absorbed, and improves the bioavailability of medicine.WithTime turn avoid medicine to liver, the infringement of kidney and first pass effect.The natural pure green Chinese environmental protection of the present invention, safe and reliable,Curative effect is original, in cough-relieving, reduces phlegm, has the medical treatment that endo-medicine can not play in terms of chronic obstructive pulmonary disorders and smoking cessationHealth-care effect.
2, the present invention can pass through tea-drinking, oral can play equally cough-relieving, reduce phlegm, chronic obstructive pneumonopathy, smoking cessationEffect.
3, the present invention passes through CO2 supercritical fluid extraction component, and CO2 supercritical extraction is that a kind of collection extracts and separatesWith one, again essentially without the new technique of organic solvent.The principle of CO2 supercritical fluid extraction (SFE) separation process is profitBy the relation of the solvability of supercritical fluid Yu its density, i.e. utilize the pressure and temperature shadow to supercritical fluid solvabilityRing and carry out.CO2 in the supercritical state, is the single phase between liquids and gases, has close with liquidDensity, diffusion coefficient is 10～100 times of liquid, has preferable permeability and solvability to material.When supercritical fluid withMaterial contact to be separated so that it is selectively the composition of polarity size, boiling point height and molecular size range is extracted successivelyOut.Certainly, the extract obtained by corresponding each pressure limit is unlikely to be single, but can with control condition most preferably thanThe blending constituent of example, then the method by decompression, intensification makes supercritical fluid become common gases, is extracted material the most completeOr substantially separate out, thus reach the purpose of separating-purifying.
The outstanding advantages of CO2 supercritical extraction medium-height grass the effective elements of the medicine: 1. can be operated at approximately room temperature, anti-Controlling some destroyed or loss to heat-labile medicinal herb components, 2. extract has the fragrance that natural plants is pure, 3. extractsTaking thing active component to retain fully, color and luster is good, and purity is high, and 4. extraction yield is high, saves the energy, 5. hardly with having in extraction processMachine solvent, organic solvent-free residual in extract, nuisanceless to environment, 6. CO2 itself is inert, can be recycled, and price is justPreferably.
Medicine toxicity is tested
Select Kun Ming mice 18, be divided into 3 groups, respectively A, B, C, often organize each 6, male and female half and half, body weight 18～About 20g.Fasting 12 hours.A group mice respectively injects the concentrated solution 2ml of 1 traditional cigarette.B group mice respectively injects 1 present inventionThe concentrated solution 2ml of non-tobacco Medicated cigarette.C group each injecting normal saline 2ml.After 2 hours, A group mice is the most dead, B group mice withCompare before injection, activity freely, spirit more, and none example is dead, C group mice with inject before compared with, normally, do not have changeChange.Acute toxicity test conclusion shows: traditional cigarette is poisonous, and non-tobacco Medicated cigarette of the present invention is the most nontoxic, also has enhancing immunityPower etc. act on.
Clinical data
The smoker 80 having looked for voluntary smoking cessation at this city in 2009 8, the age between 35～70, the smoking time limit is up to 10 yearsAbove, these 80 smokers are randomly divided into 4 groups, often organize each 20 people.First group of A smoker aspirates non-tobacco Medicated cigarette of the present invention；SecondGroup B smoker aspirates tradition tobacco smoke；3rd group of C smoker's tea-drinking non-tobacco of the present invention Medicated cigarette；4th group of D is non-smoking people suctionNon-tobacco Medicated cigarette of the present invention.And they are carried out relevant projects inspection: nicotine content, pulmonary's color, lung fiber journey in urineDegreeization, chronic obstructive pulmonary disease.Result see table.
Projects check result table
Proved by clinical data, pure Chinese medicine non-tobacco Medicated cigarette can nicotine in purged body, remove pulmonary's dust particle,Smog dipping thing, repairs lung tissue, treats chronic obstructive pulmonary disease, and smoking cessation and quit smoking rate are up to 98%.The present invention can meet cigaretteThe people, to the physiology of traditional cigarette and psychology dual requirements, not only can aspirate but also can still have non-smoker's pulmonary disease necessarily with tea-drinkingCurative effect.
Embodiment 1
By weight weighing yunnan puer tea 30～40 parts, Flos Rosae Rugosae 20～30 parts, Thamnolia vermicularis (Ach.) Asa-hina 20～30 parts, LINGDANCAO respectively20～30 parts, Stigma Croci 15～25 parts, Folium Ginkgo 15～25 parts, use ethanol mix homogeneously, the moistening shape of stirring, keep room temperature 20～Between 30 degree, sealed fermenting 3 days, dry, then with tabacco cutter, above-mentioned article cut into the thin filament of about 5mm, circulation of qi promoting stream of going forward side by sideIt is dried.
2, by weight weighing Radix Rubiae 10～20 parts the most respectively, Flos Lonicerae 20～30 parts, Flos Chrysanthemi 15～25 parts, Herba Taraxaci 20～30 parts, lavandula angustifolia 15～25 parts, Folium Nelumbinis 15～25 parts, Cacumen Platycladi 10～20 parts, Semen Oroxyli 10～20 parts, CitrusaurantiumL.Var.amara Engl. 15～25Part, Herba Lophatheri 15～25 parts, Herba Pogostemonis 10～20 parts, mix homogeneously, join in the ethanol of 50%～80%, is heated to reflux for the first time40min, filters；Second time is heated to reflux 20min, filters, merging filtrate, standby.
3, by weight weigh the most respectively Radix Glehniae 10～20 parts, Aloe 10～20 parts, Fructus Perillae 15～25 parts, Radix Rhodiolae 15～25 parts, Cortex Magnoliae Officinalis 15～25 parts, Fructus Fici 10～20 parts, the Radix Astragali 15～25 parts, Radix Notoginseng 10～20 parts, Radix Angelicae Sinensis 10～20 parts, Radix Glycyrrhizae15～25 parts, Flos Caryophylli 15～25 parts, Radix Platycodonis 20～30 parts, Radix Puerariae 10～20 parts, Radix Panacis Quinquefolii 20～30 parts, Bulbus Lilii 20～30 parts,Fructus Momordicae 20～30 parts, Poria 10～20 parts, Semen Sterculiae Lychnophorae 10～20 parts, pericarpium citri grandis 15～25 parts, Bulbus Fritillariae Cirrhosae 10～20 parts, Rhizoma Polygonati Odorati15～25 parts, Semen Sinapis 15～25 parts, Rhizoma Imperatae 10～20 parts, Bulbus Allii Macrostemonis 15～25 parts, Radix Ophiopogonis 10～20 parts, Rhizoma Chuanxiong 10～20Part, Semen Coicis 15～25 parts, Semen Armeniacae Amarum 10～20 parts, Pericarpium Citri Reticulatae 15～30 parts, Lignum Aquilariae Resinatum 15～25 parts, Ganoderma 10～20 parts of mixing are allEven, pulverize, cross 50 mesh sieves, be placed in the extraction kettle of 1L, add coextraction agent ethanol, if extracting pressure 15～45Mpa, extraction temperatureSpend 30～50 DEG C, separating still pressure 10～30Mpa, separation temperature 30～60 DEG C, CO2 flow 1L～3L/min, extraction time1.0h～3.0h.Filter, obtain extract.
4, above-mentioned 2,3 two extracting solution are merged, be concentrated to density 1.20～1.30, standby.
5, above-mentioned concentrated solution is uniformly sprayed onto on above-mentioned 1, dries in the shade, use ZB45 cigarette making machine equipment to carry out rolling into ultralowTar finished product.
Embodiment 2
1, by weight weigh the most respectively yunnan puer tea 30～40, Flos Rosae Rugosae 20～30, Thamnolia vermicularis (Ach.) Asa-hina 20～30, LINGDANCAO 20～30, Stigma Croci 15～25, Folium Ginkgo 15～25, use ethanol mix homogeneously, the moistening shape of stirring, keep close between room temperature 20～30 degreeClose fermentation 3 days, dry, then with tabacco cutter, above-mentioned article are cut into the thin filament of about 5mm, circulation of qi promoting fluidized drying of going forward side by side.
2, by weight weigh the most respectively Radix Rubiae 10～20 parts, Flos Lonicerae 20～30 parts, Flos Chrysanthemi 15～25 parts, Herba Taraxaci 20～30 parts, lavandula angustifolia 15～25 parts, Folium Nelumbinis 15～25 parts, Cacumen Platycladi 10～20 parts, Semen Oroxyli 10～20 parts, CitrusaurantiumL.Var.amara Engl. 15～25Part, Herba Lophatheri 15～25 parts, Herba Pogostemonis 10～20 parts, mix homogeneously, join in the ethanol of 50%～80%, is heated to reflux for the first time40min, filters；Second time is heated to reflux 20min, filters, merging filtrate, standby.
3, by weight weigh the most respectively Radix Glehniae 10～20 parts, Aloe 10～20 parts, Fructus Perillae 15～25 parts, Radix Rhodiolae 15～25 parts, Cortex Magnoliae Officinalis 15～25 parts, Fructus Fici 10～20 parts, the Radix Astragali 15～25 parts, Radix Notoginseng 10～20 parts, Radix Angelicae Sinensis 10～20 parts, Radix Glycyrrhizae15～25 parts, Flos Caryophylli 15～25 parts, Radix Platycodonis 20～30 parts, Radix Puerariae 10～20 parts, Radix Panacis Quinquefolii 20～30 parts, Bulbus Lilii 20～30 parts,Fructus Momordicae 20～30 parts, Poria 10～20 parts, Semen Sterculiae Lychnophorae 10～20 parts, pericarpium citri grandis 15～25 parts, Bulbus Fritillariae Cirrhosae 10～20 parts, Rhizoma Polygonati Odorati15～25 parts, Semen Sinapis 15～25 parts, Rhizoma Imperatae 10～20 parts, Bulbus Allii Macrostemonis 15～25 parts, Radix Ophiopogonis 10～20 parts, Rhizoma Chuanxiong 10～20Part, Semen Coicis 15～25 parts, Semen Armeniacae Amarum 10～20 parts, Pericarpium Citri Reticulatae 15～30 parts, Lignum Aquilariae Resinatum 15～25 parts, Ganoderma 10～20 parts of mixing are allEven, pulverize, cross 50 mesh sieves, be placed in the extraction kettle of 1L, add coextraction agent ethanol, if extracting pressure 15～45Mpa, extraction temperatureSpend 30～50 DEG C, separating still pressure 10～30Mpa, separation temperature 30～60 DEG C, CO2 flow 1L～3L/min, extraction time1.0h～3.0h.Filter, obtain extract；
4, above-mentioned 2,3 two extracting solution are merged, be concentrated to density 1.20～1.30, standby；
5, above-mentioned concentrated solution is uniformly sprayed onto on the cigarette filament that above-mentioned steps 1 obtains；
6, weigh mentha leave by ratio of weight and the number of copies, pulverize, take powder load extraction kettle, extracting pressure be 6.0～9.0MPa, extraction temperature is 30 DEG C～55, under conditions of CO2 flow is 1L～3L/min, use CO2 supercritical extraction 1.0～2.0h, collects Oleum menthae, with anhydrous sodium sulfate dehydration, filter paper, filtration, uses 95% ethanol dilution.The cigarette filament that step 1 obtainsOn, dry in the shade, use ZB45 cigarette making machine equipment to carry out rolling into ultra-low tar finished product.
Embodiment 4
1, by weight weighing yunnan puer tea 40 parts, Flos Rosae Rugosae 25 parts, Thamnolia vermicularis (Ach.) Asa-hina 25 parts, LINGDANCAO 20 parts, safranine respectivelySpend 20 parts, Folium Ginkgo 15 parts, use ethanol mix homogeneously, the moistening shape of stirring, keep sealed fermenting 3 days between room temperature 20～30 degree,Dry, then with tabacco cutter, above-mentioned article are cut into the thin filament of about 5mm, circulation of qi promoting fluidized drying of going forward side by side.
2, by weight weigh the most respectively 15 parts of Radix Rubiae, Flos Lonicerae 25 parts, Flos Chrysanthemi 20 parts, Herba Taraxaci 20 parts, lavandula angustifolia 15 parts,15 parts of Folium Nelumbinis, Cacumen Platycladi 20 parts, Semen Oroxyli 15 parts, CitrusaurantiumL.Var.amara Engl. 15 parts, Herba Lophatheri 15 parts, Herba Pogostemonis 15 parts, mix homogeneously, joinIn the ethanol of 60%, it is heated to reflux 40min for the first time, filters；Second time is heated to reflux 20min, filters, merging filtrate, standby.
3, by weight weighing Radix Glehniae 15 parts, Aloe 15 parts, Fructus Perillae 20 parts, Radix Rhodiolae 15 parts, Cortex Magnoliae Officinalis 15 parts, nothing respectivelyFlowers and fruits 10 parts, the Radix Astragali 20 parts, Radix Notoginseng 15 parts, Radix Angelicae Sinensis 15 parts, 15 parts of Radix Glycyrrhizae, Flos Caryophylli 15 parts, Radix Platycodonis 20 parts, Radix Puerariae 10 parts, the WestJoin 30 parts, Bulbus Lilii 20 parts, Fructus Momordicae 20 parts, 15 parts of Poria, Semen Sterculiae Lychnophorae 15 parts, pericarpium citri grandis 20 parts, Bulbus Fritillariae Cirrhosae 20 parts, Rhizoma Polygonati Odorati 15Part, Semen Sinapis 15 parts, Rhizoma Imperatae 20 parts, Bulbus Allii Macrostemonis 15 parts, Radix Ophiopogonis 15 parts, Rhizoma Chuanxiong 15 parts, Semen Coicis 15 parts, 15 parts of Semen Armeniacae Amarum, Pericarpium Citri Reticulatae155 parts, Lignum Aquilariae Resinatum 155 parts, 15 parts of mix homogeneously of Ganoderma, pulverize, cross 50 mesh sieves, be placed in the extraction kettle of 1L, add coextraction agentEthanol, if extracting pressure 25Mpa, extraction temperature 45 DEG C, separating still pressure 15Mpa, separation temperature 50 DEG C, CO2 flow 2L/min,Extraction time 1.5h.Filter, obtain extract；
4, above-mentioned 2,3 two extracting solution are merged, be concentrated to density 1.25, standby；
5, above-mentioned concentrated solution is uniformly sprayed onto on the cigarette filament that above-mentioned steps 1 obtains；
6, weigh mentha leave 0.6kg, pulverize, take powder and load extraction kettle.Being 8.5MPa in extracting pressure, extraction temperature is40 DEG C, under conditions of CO2 flow is 2L/min, use CO2 supercritical extraction 1.5h, collect Oleum menthae, take off with anhydrous sodium sulfateWater, filter paper, filtration, take in right amount, use 95% ethanol dilution, spray on the cigarette filament that step 1 obtains.
7, weighing Golden jujube by ratio of weight and the number of copies, add 70% alcohol heating reflux 2h, filter, filtrate is sprayed onto step 1 and obtainsOn the cigarette filament obtained, dry in the shade, use ZB45 cigarette making machine equipment to carry out rolling into ultra-low tar finished product.
The present invention can summarize with other the concrete form without prejudice to the spirit or essential characteristics of the present invention.Therefore, nothingOpinion is from the point of view of which point, and the embodiment above of the present invention all can only be considered the description of the invention and can not limit thisBright, claims indicate the scope of the present invention, therefore, in the implication suitable with claims of the present invention and scopeAny change, is all considered as being included within the scope of the present invention.