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CN103190956A - Laser therapeutic instrument based on OCT (optical coherence tomography) imaging system - Google Patents

Laser therapeutic instrument based on OCT (optical coherence tomography) imaging system
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Publication number
CN103190956A
CN103190956ACN2013100618739ACN201310061873ACN103190956ACN 103190956 ACN103190956 ACN 103190956ACN 2013100618739 ACN2013100618739 ACN 2013100618739ACN 201310061873 ACN201310061873 ACN 201310061873ACN 103190956 ACN103190956 ACN 103190956A
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China
Prior art keywords
laser
laser therapeutic
coherence tomography
output
flashlight
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CN2013100618739A
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Chinese (zh)
Inventor
胡建明
陈方林
谭波
崔玉亭
杨盼
丁帅军
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胡建明
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Priority to CN2013100618739ApriorityCriticalpatent/CN103190956A/en
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Abstract

The invention discloses a laser therapeutic instrument based on an OCT imaging system. The laser therapeutic instrument comprises a coherence tomography imaging system and a laser therapeutic system, wherein a radiation range of a laser output optical path of the laser therapeutic system is located in a radiation range of signal light of a measurement branch of the coherence tomography imaging system; the laser therapeutic instrument adopts a structure combining the coherence tomography imaging system with the laser therapeutic system; imaging characteristics of the coherence tomography imaging system are utilized; before therapy, a therapeutic point range can be tracked, and after therapy, the therapeutic effect can be tracked and confirmed; moreover, laser is used as a therapeutic means, and the laser therapeutic instrument is particularly suitable for treating disease of subcutaneous tissues and internal organs and can be applied to all laser therapeutic instruments, so that functions are achieved; and the coherence tomography imaging system and the laser therapeutic system both adopt an optical principle, and the laser therapeutic instrument is small in size, good in usage flexibility and convenient to operate.

Description

Laser therapeutic apparatus based on the OCT imaging system
Technical field
The present invention relates to a kind of for medical diagnosis on disease and therapeutic device, particularly a kind of laser therapeutic apparatus based on the OCT imaging system.
Background technology
Using laser action in human body and treat disease, mainly is to utilize laser to the heat effect of biological tissue, produces heat after irradiated tissue absorbs luminous energy, and the temperature of organization internal is risen, and tissue is solidified, burns, excises or vaporizes.Have following having a few: go out insufficiency of blood or not hemorrhage, can avoid cancerous cell diffusion transfer in the art; Surgical field of view is clear, operation quality height; Do not have the machinery contact in the art, thereby avoided the contact infection; Pain is light in the art, and after-operation response is little.But laser therapy can't be determined therapeutic effect as one for the treatment of means after treatment, also can't follow the tracks of the point of care scope before treatment; Particularly for subcutaneous tissue, lack effectively inspection and means of tracking especially.
In the prior art, a kind of ultrasonic therapeutic apparatus occurred, utilized hyperacoustic high-strength focused realization therapeutic purposes, be mated and be provided with Ultrasonic-B probe, had and follow the tracks of the function that detects, treats and detect therapeutic effect; But ultrasonic therapeutic apparatus has specific feature, and as be unableing to do without transmission medium such as water, thereby motility is relatively poor when using; Simultaneously, ultrasonic therapeutic apparatus treatment head adds that the Ultrasonic-B probe volume is bigger, can't enter human body and operate, and uses comparatively inconvenience, and seems helpless for the disease of some human body depths, and particularly intracorporeal organ operation can't be carried out.
Therefore, need a kind of equipment that has detection, follows the tracks of and treat, utilize laser as treatment means, can follow the tracks of definite therapeutic effect after before treatment, can following the tracks of point of care scope and treatment, be specially adapted to the disease treatment of subcutaneous tissue, intracorporeal organ, and volume is little, uses motility good, handled easily.
Summary of the invention
In view of this, purpose of the present invention provides a kind of laser therapeutic apparatus based on the OCT imaging system, utilize laser as treatment means, can follow the tracks of definite therapeutic effect after before treatment, can following the tracks of point of care scope and treatment, be specially adapted to the disease treatment of subcutaneous tissue, intracorporeal organ, and volume is little, uses motility good, handled easily.
Laser therapeutic apparatus based on the OCT imaging system of the present invention comprises coherence tomography system and laser therapeutic system, and the output laser optical path range of exposures of described laser therapeutic system is positioned at the range of exposures of the flashlight that the measurement of coherence tomography system props up.
Further, comprise that also a flashlight that the measurement of the output laser of laser therapeutic system and coherence tomography system is propped up is coupled into the output coupling mirror of same output light path, the flashlight that the output laser of described laser therapeutic system and the measurement of coherence tomography system are propped up alternately or output synchronously;
Further, the reflected light full impregnated that described output coupling mirror is all-trans to the output laser of laser therapeutic system and flashlight that the measurement of coherence tomography system is propped up and tissue reflect, this output coupling mirror is the 45 setting;
Further, the flashlight that props up of the measurement of the output laser of described laser therapeutic system and coherence tomography system is coupled into a branch of coaxial collimated beam by output coupling mirror and outputs to condenser lens behind collimating mirror collimation separately;
Further, also comprise the galvanometer for scanning, the flashlight that the measurement of the coherence tomography system that is set forth in is propped up is through collimating and be coupled into same output light path with the output laser of laser therapeutic system by output coupling mirror after vibration mirror reflected;
Further, also comprise endoscopic system, the fiber-optic transfer of the conduit of the output light path of described output coupling mirror by being positioned at endoscopic system;
Further, also comprise endoscopic system, be coupled into the interior same optical fiber of conduit of endoscopic system after the flashlight that the output laser of laser therapeutic system and the measurement of coherence tomography system are propped up focuses on respectively;
Further, also comprise endoscopic system, pass through fiber-optic transfer separately after the flashlight that the output laser of laser therapeutic system and the measurement of coherence tomography system are propped up focuses on respectively respectively, described optical fiber is positioned at the conduit of endoscopic system.
Beneficial effect of the present invention: the laser therapeutic apparatus based on the OCT imaging system of the present invention, adopt coherence tomography system and laser therapeutic system structure combining, utilize the imaging characteristics of coherence tomography system, before treatment, can diagnose, determine the point of care scope, in operation, can monitor operation process and surgical effect, can follow the tracks of definite therapeutic effect after the treatment, and utilize laser as treatment means, be specially adapted to the disease treatment of subcutaneous tissue, intracorporeal organ, and be applicable to the attainable function of all laser therapeutic apparatus; Because coherence tomography system and laser therapeutic system are optical principle, and volume is little, use motility good, handled easily.
Description of drawings
Below in conjunction with drawings and Examples the present invention is further described.
Fig. 1 is structural principle sketch map of the present invention;
Fig. 2 is second kind of structural representation of optic path of the present invention;
Fig. 3 is the third structural representation of optic path of the present invention.
The specific embodiment
Fig. 1 is structural principle sketch map of the present invention, as shown in the figure: the laser therapeutic apparatus based on the OCT imaging system of present embodiment, comprise coherence chromatographic imaging (OCT)system 2 and lasertherapeutic system 1, the output laser optical path range of exposures of described lasertherapeutic system 1 is positioned at the range of exposures of the flashlight that the measurement of coherence tomography system props up; Both light paths can be coupled and form a light path, also can export by light path separately respectively, all can realize the two range of exposures overlaid or identical purpose.
In the present embodiment, comprise that also a flashlight that the measurement of the output laser of lasertherapeutic system 1 andcoherence tomography system 2 is propped up is coupled into theoutput coupling mirror 3 of same output light path, the flashlight that the output laser of described lasertherapeutic system 1 and the measurement ofcoherence tomography system 2 are propped up is output alternately; The flashlight that utilizesoutput coupling mirror 3 that the measurement of the output laser of lasertherapeutic system 1 andcoherence tomography system 2 is propped up is coupled into same light path, make that device structure of the present invention is simple, volume is little, reduce cost, and the two light path shares, make that tracking detects, treatment is more accurate, avoid occurring asynchronous and the inaccurate problem in treatment orientation; The flashlight that the output laser of laser therapeutic system and the measurement of coherence tomography system are propped up alternately output avoids the two to interfere with each other, generally control by automatic control system, control the emission of the two and close frequency, belong to general automation field, do not repeat them here.
In the present embodiment, flashlight and reflected light full impregnated that the output laser of 3 pairs of lasertherapeutic systems 1 of described output coupling mirror is all-trans and the measurement ofcoherence tomography system 2 is propped up, this output coupling mirror is the 45 setting; 45 refers to: the output laser of laser therapeutic system is 45 and is incident to output coupling mirror and total reflection, the flashlight that the measurement of coherence tomography system is propped up is 45 and is delivered to output coupling mirror and total transmissivity, and the two is gone the same way by the light path of output coupling mirror transmission and reflection.
In the present embodiment, the flashlight that the output laser of described lasertherapeutic system 1 and the measurement ofcoherence tomography system 2 are propped up is coupled into a branch of coaxial collimated beam by output coupling mirror and outputs tocondenser lens 6 behind collimating mirror collimation separately; As shown in the figure, thelaser alignment mirror 4 of the output laser of lasertherapeutic system 1 beforeoutput coupling mirror 3, the flashlight collimating mirror 5 of the flashlight that the measurement ofcoherence tomography system 2 is propped up beforeoutput coupling mirror 3.
In the present embodiment, also comprise thegalvanometer 12 for scanning, the flashlight that the measurement of the coherence tomography system that is set forth in 2 is propped up through collimation and aftergalvanometer 12 reflection and the output laser of lasertherapeutic system 1 be coupled into same output light path byoutput coupling mirror 3; Make the present invention when the treatment that is used for subcutaneous pathological tissues or beauty treatment, form sweep limits, with obtain comparatively accurately, information on a large scale; For the treatment in later stage is prepared.
When the present invention used, for treatment or the beauty treatment of subcutaneous pathological tissues, the flashlight that the output laser of described laser therapeutic system and the measurement of coherence tomography system are propped up focused on behind the line focus lens and shines lesion region or the beauty treatment zone that needs treatment; Described laser therapeutic apparatus based on the OCT imaging system can be doctor or cosmetologist's manual adjustments irradiation area, also the treatment head of therapeutic instrument can be placed on the electric platforms, by computer regulating and controlling irradiation area.
Fig. 2 is second kind of structural representation of optic path of the present invention; The difference of present embodiment and above-described embodiment only is: in the present embodiment, present embodiment comprisesendoscopic system 7, is not provided withgalvanometer 12; The fiber-optic transfer of the conduit of the output light path of describedoutput coupling mirror 3 by being positioned atendoscopic system 7; As shown in the figure, output light path inputs in the conduit ofendoscopic system 7 byoptical fiber 8; Utilize endoscope to realize detecting and treating for human internal organs, as intestinal, stomach etc.; Theendoscopic system 7 general flexible catheter formula endoscopic systems that adopt, structure and the operation of this endoscopic system and conduit thereof belong to prior art, do not repeat them here.
Fig. 3 is the third structural representation of optic path of the present invention; In the present embodiment, compriseendoscopic system 7 equally, but do not comprisegalvanometer 12 andoutput coupling mirror 3, after focusing on respectively, the flashlight that the output laser of lasertherapeutic system 1 and the measurement ofcoherence tomography system 2 are propped up is coupled into the interior same optical fiber of conduit ofendoscopic system 7, as shown in the figure, the present invention utilizes 2 * 1 fiber couplers 13 to realize above-mentioned purpose, the output laser of lasertherapeutic system 1 collimates also throughlaser alignment mirror 4 and enters 2 * 1 fiber couplers 13 byoptical fiber 10 after theline focus lens 4a focusing, and the flashlight that the measurement ofcoherence tomography system 2 is propped up enters 2 * 1 fiber couplers 13 byoptical fiber 11 after flashlight collimating mirror 5 collimations and line focus lens 5a focusing; The flashlight that the output laser of described lasertherapeutic system 1 and the measurement ofcoherence tomography system 2 are propped up alternately or is synchronously exported; Do not adopt output coupling mirror, still can realize goal of the invention.
Certainly, can also adopt the structure that has following difference with the third structure:
Can compriseendoscopic system 7 equally, after focusing on respectively, passes through the flashlight that the output laser of lasertherapeutic system 1 and the measurement ofcoherence tomography system 2 are propped up fiber-optic transfer separately respectively, the output laser that is lasertherapeutic system 1 is exported by independent optical fiber, and the flashlight that the measurement ofchromatographic imaging system 2 is propped up is by another independent optical fiber output; Two optical fiber all are positioned at the conduit ofendoscopic system 7; Adopt separately independently that optical fiber transmits, the inessential trouble that can avoid maloperation to bring, and an optical fiber breaks down therein, and still tool has certain effect.
Explanation is at last, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although with reference to preferred embodiment the present invention is had been described in detail, those of ordinary skill in the art is to be understood that, can make amendment or be equal to replacement technical scheme of the present invention, and not breaking away from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.

Claims (8)

CN2013100618739A2013-02-272013-02-27Laser therapeutic instrument based on OCT (optical coherence tomography) imaging systemPendingCN103190956A (en)

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Cited By (7)

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CN104095604A (en)*2013-12-242014-10-15北京华科创智健康科技股份有限公司Endoscopic OCT (optical coherence tomography) probe with operating distance being capable of automatically and continuously adjusted
CN105769127A (en)*2016-05-052016-07-20中国科学院苏州生物医学工程技术研究所Diagnosis and treatment equipment based on confocal technology and control method thereof
CN110812704A (en)*2019-10-312020-02-21中国医学科学院生物医学工程研究所Optical fiber adapter and OCT imaging system for in-vivo tissue photodynamic therapy
CN111437517A (en)*2020-04-072020-07-24中山大学Laser treatment system
CN111437518A (en)*2020-04-072020-07-24中山大学Laser treatment device
CN113520322A (en)*2021-07-162021-10-22福州大学 A colorectal cancer diagnosis and treatment instrument integrating OCT real-time imaging and femtosecond laser
CN113520296A (en)*2021-07-162021-10-22福州大学 An optical imaging device for disease diagnosis and treatment and its working method

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CN1875242A (en)*2003-10-272006-12-06通用医疗公司 Method and apparatus for optical imaging using frequency domain interferometry
CN101032390A (en)*2007-03-292007-09-12浙江大学Endoscopic imaging system in bulk optics biopsy spectral coverage OCT
CN201101518Y (en)*2007-07-032008-08-20浙江大学Common channel type endoscopic optical coherent chromatography imaging system
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Cited By (9)

* Cited by examiner, † Cited by third party
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CN104095604A (en)*2013-12-242014-10-15北京华科创智健康科技股份有限公司Endoscopic OCT (optical coherence tomography) probe with operating distance being capable of automatically and continuously adjusted
CN104095604B (en)*2013-12-242015-12-02北京华科创智健康科技股份有限公司The endoscopic OCT probe that operating distance Automatic continuous regulates
CN105769127A (en)*2016-05-052016-07-20中国科学院苏州生物医学工程技术研究所Diagnosis and treatment equipment based on confocal technology and control method thereof
CN105769127B (en)*2016-05-052019-03-29中国科学院苏州生物医学工程技术研究所A kind of diagnostic equipment and its control method burnt based on copolymerization
CN110812704A (en)*2019-10-312020-02-21中国医学科学院生物医学工程研究所Optical fiber adapter and OCT imaging system for in-vivo tissue photodynamic therapy
CN111437517A (en)*2020-04-072020-07-24中山大学Laser treatment system
CN111437518A (en)*2020-04-072020-07-24中山大学Laser treatment device
CN113520322A (en)*2021-07-162021-10-22福州大学 A colorectal cancer diagnosis and treatment instrument integrating OCT real-time imaging and femtosecond laser
CN113520296A (en)*2021-07-162021-10-22福州大学 An optical imaging device for disease diagnosis and treatment and its working method

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Application publication date:20130710


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