CN103126806A - High-wet-strength wound dressing - Google Patents

Abstract

The invention relates to a high-wet-strength wound dressing. Specifically, the wound dressing is formed by three layers of structures, outer layer material is sol fiber, middle layer material is woven fabric or knitted fabric or other nonwoven fabric, and the three layers of structures are connected together in a physical or chemical mode. The wound dressing can be used for nursing wounds of chronic ulcers such as a vein blood stasis ulcer, a stress ulcer, a diabetic foot ulcer and other chronic ulcer wounds including cave type or depressed type or the like ulcer wounds.

Description

The high wet strength wound dressing

Technical field

The present invention relates to a kind of high wet strength wound dressing.This dressing comprises three-decker: skin is moisture absorption colloidal sol fiber, and the intermediate layer is the non-woven fabrics of woven fabric or knitted fabric or another non-colloidal sol fiber preparation; Three-decker links together by physics or chemical mode.

Background technology

As everyone knows, the high wet strength wound dressing has important effect in the wound care that contains moderate or severe transudate, it not only can fully absorb the transudate in wound healing process, but also can keep moistening environment for wound, is conducive to the healing of wound.After yet this class dressing absorbs transudate, intensity can step-down.The low wound dressing of wet strength cracky and increase the weight of the degree of difficulty of wound care work in the removal process even has damaged wound dressing to remain in the possibility of wound surface, can cause the accompanying infection of wound and peripheral skin.

General wound has a large amount of transudates in agglutination, therefore the colloidal sol fiber wound dressing that needs clinically to have high-hygroscopicity absorbs transudate, to prevent bacteria breed and infection, optimal situation is can be removed by full wafer after wound dressing absorbs transudate, and can not cause wound dressing to absorb wet strength step-down after transudate and easily damaged.Take the modified cellulose wound dressing as example, this dressing can absorb the transudate of 20 times of own wts.Modal larger wound dressing (10 * 20cm) weight are generally 2 ~ 3g, after fully absorbing, and this dressing 60g or more that can weigh.For avoiding occurring the dressing breakage in the wound dressing Renewal process, the wet strength of wound dressing just there is higher requirement.

WO 2009/0287130 has done some trials in this respect.It is that the mode with acupuncture is woven in some yarns in dressing on the basis of carboxymethyl cellulose dressing (Aquacel).After the abundant moisture absorption of dressing, these sewing threads that interweave can make Aquacel become more firmly and be sturdy like this, and the full wafer that is beneficial to dressing is removed.

US Patent No. 3096228 has been announced a kind of method of fortifying fibre product wet strength.It is to introduce a kind of reagent that is named as Biformyl in cellulose fibre, Biformyl can with the group polymerizations, crosslinked such as cellulosic hydroxyl, cellulosic molecule is linked together more closely, thereby can when keeping this material high-hygroscopicity and becoming colloidality, can also keep higher wet strength.Yet this method needs higher temperature, but also need to add other chemical reagent.In addition, this kind method also can affect comfortableness and the flexibility of product.

US Patent No. 6372675B1 discloses a kind of method that strengthens the non-woven fabrics fiber wet strength, and this method comprises the random rearrangement bonding of non-cellulose fibre and strengthens wet strength with the requisite emulsion binder bonding that does not contain formaldehyde.The acrylonitrile monemer that emulsion binder comprises at least 6.7 % by weight comes bonding non-cellulose fibrid, thereby has at least 10% improvement with respect to the wet strength of the non-woven fabrics of the emulsion binder that does not contain formaldehyde and acrylonitrile monemer.

US Patent No. 2559220 discloses a kind of method of improving fiber-like product wet strength by introducing tripolycyanamide aldehyde, and tripolycyanamide aldehyde fibre technology can extensively improve the paper product such as writing paper, coated papers.On broad sense, can be used for suitable non-woven fabrics, film forming and press process, and some novel fiber-like products can be improved its wet strength and other physical characteristic greatly.

Summary of the invention

In order to overcome above-mentioned technical problem, the invention provides a kind of high wet strength wound dressing with three-decker, high-hygroscopicity colloidal sol material is contained in the skin of this wound dressing (1) and (3), intermediate layer (2) is the adhesive-bonded fabric of woven fabric or knitted fabric or non-colloidal sol fiber, three-decker is bonded together by physics or chemical mode, forms an existing high moisture absorption and becomes colloidality that the wound dressing of certain wet strength is arranged again.The grammes per square metre of described wound dressing is 80-400g/100cm², preferred 100-300g/100cm²

The material of the skin of high wet strength wound dressing of the present invention (1) and (3) can be selected from modified cellulose fibre, modified chitosan fiber, alginate fiber or its combination or blending.Wherein, modified cellulose fibre is that carboxymethyl cellulose fiber or water-immiscible solvent spin cellulose alkylsulfonate fiber, and the substitution value of modified cellulose fibre is 0.05-0.45, preferred 0.28-0.34.Modified chitosan fiber is acylation chitosan fiber or Carboxymethyl chitosan fiber, and the substitution value of modified chitosan fiber is 0.05-0.45, preferred 0.28-0.34.Alginate fiber is calcium fiber type or calcium/sodium fiber type.

The material of the skin of high wet strength wound dressing of the present invention (1) and (3) can also be the blending thing of modified cellulose fibre, modified chitosan fiber or alginate fiber and other non-colloidal sol fiber, and wherein other non-colloidal sol fiber is selected from chitin fiber, cellulose fibre or Lyocell fiber.

The woven fabric that use in the intermediate layer of high wet strength wound dressing of the present invention (2) or knitted fabric are by yarn or the long filament preparation of cotton, hair, terylene, nylon, polypropylene, polyvinyl or viscose, and the line density of this yarn or long filament is between 100dtex-2000dtex.The adhesive-bonded fabric of the non-colloidal sol fiber that uses is by the fiber preparation of cotton, hair, terylene, nylon, polypropylene, polyvinyl or viscose, and its fibre fineness is between 1-5dtex, and length is between 15-105mm.

In addition, the antibacterial of silver for example or PHMB can also be contained in the skin of high wet strength wound dressing of the present invention (1) and (3) and intermediate layer (2).

The three-decker of high wet strength wound dressing of the present invention links together by physics or chemical mode.This mode can be the mode of acupuncture combination, can be also the mode of hot melt adhesive, can also be the sticking glutinous mode of chemistry of using chemical adhesive.Concrete mode depending on product requirement.If require dressing soft, preferably use the acupuncture mode, this mode both can link together three-decker effectively, can keep again the flexibility of dressing finished product.If wish that dressing is thin and strong, preferably use the hot melting cohesion mode, this mode is applying certain pressure with the heating of three kinds of structures when being bonded together always, can make very thin that dressing does.But the shortcoming of this mode is a little less than the adhesion of outer layer fiber and dressing integral body, easily to come off.Use the mode of chemical adhesive can improve this shortcoming.Chemical adhesive can be evenly distributed in fiber surface very much, therefore most of fiber can be bonded together.

Because the skin of the wound dressing that the present invention relates to contains the colloidal sol fiber, and the intermediate layer is to be similar to the woven fabric of gauze or more open knitted fabric or non-woven fabrics, therefore, advantage of the present invention is, when this dressing is used to nurse when containing moderate to the wound of severe transudate, outer field colloidal sol fiber can promptly absorb and pin transudate, thereby forms colloid, for wound provides a moistening environment, be conducive to the healing of wound.In addition, under the supporting role of intermediate layer adhesive-bonded fabric or other woven fabric or other knitted fabric, dressing is at outer colloidal sol fiber absorbs transudate and after forming colloidal sol, still can keep higher wet strength, make wound dressing can full wafer ground remove from wound surface, avoid the wound dressing fragment to remain in wound surface, cause further infection.The intermediate layer of wound dressing of the present invention woven fabric used or knitted fabric, can not absorb and form gel after running into transudate, therefore can keep very high intensity and toughness, the globality of support dressing well, be convenient to dressing and remove from the wound surface full wafer, particularly the many especially wounds of some transudates.

Another advantage of the present invention is effectively to utilize alginate fiber, modified cellulose fibre and modified chitosan fiber performance advantage separately, is combined into various dressing with special performance.Alginate fiber can be when moistening calcium ion contributing functions, be conducive to wound healing.Modified cellulose fibre has very high hygroscopicity, can be prepared into the extra-high-speed hydroscopic dressings.Modified chitosan fiber also has hemostasis and bacteria resistance function except the moisture absorption gel-forming property is arranged.

Utilize the present invention, two skins of dressing all can be used alginate fiber, perhaps all use modified cellulose fibre, perhaps all use modified chitosan fiber.Such dressing has the performance advantage of fiber separately.

Simultaneously, the present invention can also use alginate fiber in the one side of dressing, and another side uses modified chitosan fiber.In the wound that needs calcium ion, alginate fiber is simultaneously applied thereon like this; When finding that wound has infection, modified chitosan fiber simultaneously can be applied thereon.Other application mode can the rest may be inferred.

The dressing skin can also use the blending thing of any bi-material between alginate fiber, modified chitosan fiber and modified cellulose fibre, thus the dressing comprehensive function effect that realizes.In addition, the dressing skin can also use the blending thing of these three kinds of materials of alginate fiber, modified chitosan fiber and modified cellulose fibre.

In addition, the dressing skin can also use alginate fiber or modified chitosan fiber or modified cellulose fibre this type of the colloidal sol fiber and the blending thing of other non-colloidal sol fiber, thereby improve the comprehensive function effect of dressing.Such as can improve the wet strength of dressing with the Lyocell fiber blend, can further increase hemostasis and the bacteriostasis property of dressing with unmodified chitin fiber blending.

Another advantage of high wet strength wound dressing of the present invention is that the non-colloidal sol fabric in intermediate layer can have several different choice.If require final dressing dimensional stability, woven fabric is intended using in the intermediate layer.This fabric longitude and latitude structure is obvious, and good maintenance profile ability is arranged.Its material can use any textile materials such as terylene, nylon, viscose or polyvinyl.If require dressing to have elasticity preferably, knitted fabric will be used in the intermediate layer.If wish that the intermediate layer is more thinner or with skin, better interweaving property of acupuncture is arranged, non-woven fabrics can be considered to use in the intermediate layer.

High wet strength wound dressing of the present invention can be used for nursing the more chronic ulcer wound of some transudates, as venous congestion ulcer, pressure ulcer and diabetic foot ulcers and other chronic ulcer wound, comprise the ulcer wounds such as cave type or umbilicate type.

Description of drawings

Fig. 1 is the structural representation of high-hygroscopicity wound dressing of the present invention.

Fig. 2 is the longitudinal sectional drawing of Fig. 1.

The specific embodiment

Below in conjunction with accompanying drawing, the present invention is made and further describing.

In Fig. 1 and Fig. 2, this wound dressing mainly is comprised of colloidal sol fiberupper strata 1, non-colloidal sol fabricintermediate layer 2 and colloidal sol fiberlower floor 3.

Describedupper strata 1 andlower floor 3 use a class colloidal sol fiber, and for example carboxymethyl cellulose, acylation chitosan fiber and alginates or its combination or blending has very strong one-tenth colloidality and water absorption; directly contact with wound surface; absorb transudate, keep moist environment, be convenient to the healing of wound.Be in intermediate layer 2(such as gauze betweenupper strata 1 and lower floor 3), be connected withupper strata 1 andlower floor 3 by physics or chemical mode, play the effect of supporting the levels fiber, thereby can strengthen widely its wet strength.Above-mentioned fabrics can be made different dressing models making by after cutting, pack, sterilizing, 5 * 5cm for example, 10 * 10cm.

Embodiment 1

The colloidal sol fiber of upper and lower layer all uses with the carboxymethyl cellulose fiber of Lyocell fiber as the raw material preparation, and its substitution value (DS) is 0.28 ~ 0.32, and fibre fineness is 2dtex, and length is 50mm.Be prepared into modified cellulose non-woven fabrics, grammes per square metre 60gsm by combing lapping and acupuncture.Two-layer such non-woven fabrics and common cotton gauze (grammes per square metre 60gsm) are stacked, the modified cellulose non-woven fabrics outside, cotton cloth is interior, then by the acupuncture mode, treble cloths is bonded together, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this dressing is 18g/100cm²

Embodiment 2

The colloidal sol fiber of upper and lower layer all uses with the acylation chitosan of chitosan as the raw material preparation, and its substitution value (DS) is 0.28 ~ 0.34, and fibre fineness is 2dtex, and length is 50mm.Be prepared into acylation chitosan non-woven fabrics, grammes per square metre 70gsm by combing lapping and acupuncture.Two-layer such non-woven fabrics and terylene warp knitting cloth (grammes per square metre 50gsm) are stacked, the modification of chitosan non-woven fabrics outside, the dacron thread warp knitting cloth is interior, then by the acupuncture mode, treble cloths is bonded together, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this dressing is 19g/100cm²

Embodiment 3

The colloidal sol fiber of upper and lower layer all uses with the Carboxymethyl chitosan of chitosan as the raw material preparation, and its substitution value (DS) is 0.28 ~ 0.34, and fibre fineness is 2dtex, and length is 55mm.Be prepared into Carboxymethyl chitosan non-woven fabrics, grammes per square metre 65gsm by combing lapping and acupuncture.Two-layer such non-woven fabrics and nylon warp knitting cloth (grammes per square metre 60gsm) are stacked, the Carboxymethyl chitosan non-woven fabrics outside, the nylon warp knitting cloth is interior, then by the acupuncture mode, treble cloths is bonded together, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this dressing is 21g/100cm²

Embodiment 4

By combing lapping and acupuncture, M/G type alginate fiber (fineness is 1.8dtex, and length is 75mm) is prepared into non-woven fabrics, grammes per square metre 120gsm is as first outer fabric of dressing.

Using alginate fiber to prepare second when outer, the place stacks above-mentioned first outer fabric and common cotton gauze (grammes per square metre 60gsm) at lapping machine, cotton cloth is in the centre, treble cloths is simultaneously through acupuncture processing, be bonded together, then make dressing after cutting, pack, sterilizing.The hygroscopicity of this dressing is 30g/100cm²

Embodiment 5

Outer colloidal sol fiber is respectively that solvent spins cellulose alkylsulfonate fiber (60gsm) and Carboxymethyl chitosan fiber (70gsm), fibre fineness is 2dtex, length is 50mm, be prepared into non-woven fabrics by combing lapping and acupuncture, grammes per square metre 80gsm, intermediate layer fabric are terylene warp knitting cloth (50gsm).Treble cloths pressurizes by heating and links together, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 10g/100cm²

Embodiment 6

Outer colloidal sol fiber is respectively modified cellulose fibre (60gsm, fibre fineness is 2dtex, length is 50mm) and M/G type alginate fiber (120gsm, fineness is 1.8dtex, length is 75mm), is prepared into non-woven fabrics by combing lapping and acupuncture.The intermediate layer fabric is polyvinyl (50gsm).Treble cloths links together by Chemical Felter, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 21g/100cm²

Embodiment 7

Outer colloidal sol fiber is respectively acylation chitosan fiber (70gsm; fibre fineness is 2dtex, and length is 50mm) and M/G type alginate fiber (120gsm, fineness is 1.8dtex; length is 75mm), be prepared into non-woven fabrics by combing lapping and acupuncture respectively.The intermediate layer fabric is the gauze woven fabric.Treble cloths is bonded together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 25g/100cm²

Embodiment 8

Outer colloidal sol fiber be by solvent spin cellulose alkylsulfonate fiber, the Carboxymethyl chitosan fiber carries out blending and gets, fibre fineness is 2dtex, length is 50mm, is prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 80gsm.The intermediate layer fabric is the netted woven fabric of chinlon.Treble cloths is bonded together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 26g/100cm²

Embodiment 9

Outer colloidal sol fiber is that (fibre fineness is 2dtex by modified cellulose fibre, length is 50mm) and M/G type alginate fiber (fibre fineness is 1.8dtex, length is 75mm) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is water thorn Lyocell non-woven fabrics, grammes per square metre 40gsm.Treble cloths is bonded together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 18g/100cm²

Embodiment 10

Outer colloidal sol fiber is by modified cellulose fibre (fibre fineness 2dtex, length 50mm), (fibre fineness is 1.8dtex to M type alginate fiber, length is 75mm) and unmodified chitin fiber (fibre fineness is 2dtex, length is 50mm) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 55gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 15g/100cm²

Embodiment 11

Outer colloidal sol fiber is that (fibre fineness is 2dtex by modified cellulose fibre; length is 50mm), (fibre fineness is 1.8dtex to argentiferous M/G type alginate fiber; length is 75mm; silver content is 1.2 % by weight) and the acylation chitosan fiber (fibre fineness is 2dtex; length is 50mm) carry out blending and get; be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 21g/100cm²

Embodiment 12

Outer colloidal sol fiber is that (fibre fineness is 2dtex by modified cellulose fibre; length is 50mm), (fibre fineness is 1.8dtex to M/G type alginate fiber; length is 75mm; silver content is 1.2 % by weight) and argentiferous acylation chitosan fiber (fibre fineness is 2dtex; length is 50mm) carry out blending and get; be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 21g/100cm²

Embodiment 13

Outer colloidal sol fiber is that (fibre fineness is 2dtex by the argentiferous modified cellulose fibre; length is 50mm; silver content is 0.2 % by weight), (fibre fineness is 1.8dtex to argentiferous M/G type alginate fiber; length is 75mm; silver content is 1.2 % by weight) and the acylation chitosan fiber (fibre fineness is 2dtex; length is 50mm) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 21g/100cm²

Embodiment 14

Outer colloidal sol fiber is that (fibre fineness is 2dtex by modified cellulose fibre; length is 50mm), (fibre fineness is 1.8dtex to contain the M/G type alginate fiber of PHMB; length is 75mm; PHMB content is 1.5 % by weight) and the acylation chitosan fiber (fibre fineness is 2dtex; length is 50mm) carry out blending and get; be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 65gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 21g/100cm²

Embodiment 15

Outer colloidal sol fiber is that (fibre fineness is 2dtex by the argentiferous modified cellulose fibre; length is 50mm; silver content is 0.2 % by weight), (fibre fineness is 1.8dtex to argentiferous M/G type alginate fiber; length is 75mm; silver content is 1.2 % by weight) and the acylation chitosan fiber (fibre fineness is 2dtex; length is 50mm) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is argentiferous gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 21g/100cm²

Embodiment 16

Outer colloidal sol fiber is that (fibre fineness is 1.8dtex to M type calcium alginate fibre; length is 75mm) and the acylation chitosan fiber (fibre fineness is 2dtex; length is 50mm) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 20g/100cm²

Embodiment 17

Outer colloidal sol fiber is that (fibre fineness is 2dtex to modified cellulose fibre, length is 50mm), (fibre fineness is 1.8dtex to argentiferous M/G type alginate fiber, length is 75mm, silver content is 1.2 % by weight) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 70gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 24g/100cm²

Embodiment 18

Outer colloidal sol fiber is that (fibre fineness is 2dtex to modified cellulose fibre, length is 50mm), (fibre fineness is 1.8dtex to argentiferous M/G type alginate fiber, length is 75mm, silver content is 1.2 % by weight) and unmodified chitin fiber (fibre fineness 2dtex, 50 millimeters of length) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 60gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 18g/100cm²

Embodiment 19

Outer colloidal sol fiber is that (fibre fineness is 2dtex to modified cellulose fibre, length is 50mm), (fibre fineness is 1.8dtex to contain the M/G type alginate fiber of PHMB, length is 75mm, PHMB content is 1 % by weight) carry out blending and get, be prepared into non-woven fabrics by combing lapping and acupuncture respectively, grammes per square metre 70gsm.The intermediate layer fabric is the gauze woven fabric.Treble cloths links together by the acupuncture mode, then makes dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 24g/100cm²

Embodiment 20

A skin of dressing is that (fibre fineness is as 2dtex for needle punched non-woven fabrics take colloidal sol modified cellulose fibre preparation, length is 50mm, non-woven fabrics grammes per square metre 75gsm), another skin is that (fibre fineness is as 2dtex for spun-laced nonwoven fabric take chitin fiber preparation, length is 50mm, non-woven fabrics grammes per square metre 60gsm), the intermediate layer fabric is the terylene warp knitting cloth.Treble cloths by the acupuncture mode link together (during acupuncture, modified cellulose fibre is upper, the terylene warp knitting cloth in, chitin fiber under), then make dressing after cutting, pack, sterilizing.The hygroscopicity of this kind wound dressing is 12g/100cm²

Embodiment 21

Any high wet strength wound dressing according to embodiment 1-20 preparation, in Chronic Moderate to (for example diabetic foot, gangrene, the decubital ulcer) of the exudative wound of severe treated, can form gel after fully absorbing transudate, for wound provides moistening environment, be conducive to the healing of chronic wounds, and remove and more in the process of change dressings, this high wet strength wound dressing can be removed by full wafer, do not have the dressing fragment and be retained in wound and the edge, avoid further infection.Patient's pain obviously alleviates, and does not produce secondary the infection, and wound healing is accelerated.

Claims (9)

1. a high wet strength wound dressing, is characterized in that described wound dressing has three-decker, and high-hygroscopicity colloidal sol material is contained in its ectomesoderm (1) and (3), and intermediate layer (2) are the adhesive-bonded fabrics of woven fabric, knitted fabric or non-colloidal sol fiber.

2. high wet strength wound dressing according to claim 1, the grammes per square metre that it is characterized in that described wound dressing is 80-400g/100cm², preferred 100-300g/100cm²

3. high wet strength wound dressing according to claim 1, is characterized in that the skin (1) of described wound dressing and the material of (3) are selected from modified cellulose fibre, modified chitosan fiber, alginate fiber or its combination or blending.

4. high wet strength wound dressing according to claim 3, it is characterized in that described modified cellulose fibre is that carboxymethyl cellulose fiber or water-immiscible solvent spin cellulose alkylsulfonate fiber, and the substitution value of modified cellulose fibre is 0.05-0.45, preferred 0.28-0.34; Described modified chitosan fiber is acylation chitosan fiber or Carboxymethyl chitosan fiber, and the substitution value of modified chitosan fiber is 0.05-0.45, preferred 0.28-0.34; Described alginate fiber is calcium fiber type or calcium/sodium fiber type.

5. high wet strength wound dressing according to claim 1, is characterized in that the skin (1) of described wound dressing and the material of (3) are the blending things of modified cellulose fibre, modified chitosan fiber or alginate fiber and other non-colloidal sol fiber.

6. high wet strength wound dressing according to claim 5, is characterized in that described non-peptization fiber is chitin fiber, cellulose fibre or Lyocell fiber.

7. high wet strength wound dressing according to claim 1, it is characterized in that described woven fabric or knitted fabric are by yarn or the long filament preparation of cotton, hair, terylene, nylon, polypropylene, polyvinyl or viscose, the line density of described yarn or long filament is between 100dtex-2000dtex, and the adhesive-bonded fabric of described non-colloidal sol fiber is by the fiber preparation of cotton, hair, terylene, nylon, polypropylene, polyvinyl or viscose, its fibre fineness is between 1-5dtex, and length is between 15-105mm.

8. high wet strength wound dressing according to claim 1 is characterized in that described skin (1) and (3) and intermediate layer (2) also contain the antibacterial of silver for example or PHMB.

9. high wet strength wound dressing according to claim 1, is characterized in that described skin (1) and (3) and intermediate layer (2) are by the sticking glutinous mode combination of acupuncture combination, hot melt adhesive and chemistry.

Images