CN102202636A - Reservoir filling device - Google Patents
Reservoir filling deviceDownload PDFInfo
- Publication number
- CN102202636A CN102202636ACN2009801244405ACN200980124440ACN102202636ACN 102202636 ACN102202636 ACN 102202636ACN 2009801244405 ACN2009801244405 ACN 2009801244405ACN 200980124440 ACN200980124440 ACN 200980124440ACN 102202636 ACN102202636 ACN 102202636A
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- China
- Prior art keywords
- tube
- filling device
- shell
- reservoir
- positioner
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2017—Piercing means having three or more piercing ends
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2072—Venting means for internal venting
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
Abstract
Description
Technical field
The present invention relates to a kind of filling device that is used for reservoir, this reservoir will be filled from tube, this for example be for example have the rigid walls of making by glass and be provided be used for protecting inlet can be by the membranous tube of needle penetration.
Background technology
The filling device that is used for reservoir is known, and recognizes, has necessary discharging and will be cleared with the container of filling liquid, thereby reduce the filling of reservoir or the cost that recharges.
The problem that occurs when making this filling device is how to arrange discharge-channel so that do not hinder filling process or pollute filling liquid, and this filling liquid will be the medicine of some kinds usually.
US 4296786 discloses a kind of transfer device that is used for mixing the material of different vessels, and this container is respectively by the tamper sealing with the diaphragm-operated elastomeric material that can pierce through.This transfer device is formed by central body portion with from the sharp shaped material or the intubate of the outstanding a pair of alignment of the opposite side of this central body portion.This device is not provided with the discharging pin that moves independently with filling needle, and therefore has big relatively diameter according to the sharp shaped material or the intubate of the connection of this document.
Summary of the invention
Target of the present invention provides a kind of filling device, and this filling device is handled easily concerning user, makes simply and not expensive, and has eliminated the danger of fracture discharging pin during filling process.
The present invention relates to a kind of filling device, this filling device comprises:
Shell, this shell comprises:
First positioner, this first positioner is suitable for admitting the reservoir that is used for admitting liquid;
Second positioner, this second positioner is suitable for admitting the tube that comprises liquid;
The unit, this unit is connected to shell in the mode that can not discharge, and provides flow path when reservoir is admitted by first and second positioners respectively with tube;
Exhaust unit, during the emptying of tube, the path that this exhaust unit provides gas to arrive tube, and at least a portion of exhaust unit is arranged to leave the center of rotation (r of shellc) and be connected to parts.The invention is characterized in that these parts can be with respect to shell and with respect to the unit rotation that flow path is provided.
According to one embodiment of present invention, when being in their position, reservoir and tube between reservoir and tube, provide the unit of flow path to comprise the pin of end with two points.This pin can be made by the material that penetrable protection branch is clipped to the membranous any kind of the tube and the path of reservoir, and this pin can be blunt an end and be sharp in another end.
According to one embodiment of present invention, provide of the center of rotation setting of the unit of flow path along shell.
According to the abovementioned embodiments of the present invention, this unit is secured to the wall in the shell or the part of the wall in the shell in the mode that can not discharge, and this wall is suitable for making first positioner of admitting reservoir and is suitable for admitting second positioner of tube to separate.
According to one embodiment of present invention, can form circular slab, the wall of the peripheral adjacent housings of this circular slab or slidably contact with the wall of shell with respect to the parts of shell rotation.For example, circular slab can move in the track in being formed on the wall of shell.The formation of " track " prevents that circular slab is along the rotation axis r that is parallel to shellcDirection move.Alternatively, the periphery of circular slab is provided with the track that forms along this periphery, and this track is corresponding to one or more ledge of shell.
According to one embodiment of present invention, circular slab can be provided with frictional layer, this frictional layer prevents that tube from moving with respect to tube, promptly, when tube is pulled in second positioner that has assembled of filling device shell and exhaust unit when being penetrated into the inner room of tube, then frictional layer will reduce the danger of tube with respect to any displacement of rotating part.
According to one embodiment of present invention, exhaust unit comprises the discharging pin, and this discharging pin provides the path of the inner room from the tube outside to tube.Exhaust unit (5) also can comprise drain valve (5b), and this drain valve (5b) provides the half-duplex channel of clean air in the chamber, from this chamber with clean air supply discharging pin (5a)." clean air " is considered to by user or is defined as the gas of necessary quality by the maker of device.It can be an aseptic gas, but can be the gas of poorer quality.Usually, this gas will be atmospheric air.
According to this embodiment, the discharging pin is connected to rotating part, and the flow path that is used for clean air from a side of rotating part to opposite side is provided, and drain valve can be connected to the end of opening of the discharging pin that points to away from tube.Alternatively, drain valve can be connected to the wall of shell, and the path from the outer wall of shell to the clean air of the inside of the wall of shell is provided.
The present invention also relates to a kind of combination according to the tube filling device of arbitrary claim of claim 1-11 and the tool set of the tube that comprises liquid, therefore this filling device can be disposable and be permanently connected to tube, or nonexpondable and therefore can be connected to tube and break away from from tube and be connected.
Description of drawings
Illustrate in greater detail the present invention below with reference to the accompanying drawing that two preferred embodiments of the present invention are shown,
Fig. 1 illustrates the cutaway view of filling device shell, and wherein the reservoir that will the be filled tube that is in the halfway position and comprises liquid also is in the halfway position;
Fig. 2 illustrates the cutaway view of filling device shell, and wherein drain valve is arranged to leave the discharging pin.
The specific embodiment
The embodiment of the reservoir filling device of Fig. 1 is shown as the state that liquid can not be delivered to reservoir from the tube 3 that comprises liquid that is in.The embodiment of filling device comprises: theshell 1 with cylindrical outer wall; Withseparates walls 8, this separates walls is divided into two positions with shell, is used for the primary importance of thereservoir 2 that will be filled and the second position of the tube 3 that is used for being cleared.Each position is provided by the wall ofshell 1, therefore closely cooperates for the device that will be set at the there provides, and perhaps each position is provided with guiding device, the clearly final position of definition of the device that this guiding device assurance will be set up.In the simplest form, in the described position two or one only comprise the core with the form of theseparates walls 8 that does not have outer wall.The position that comprises guiding device is called positioner.
The embodiment of filling device also comprises fillingneedle 4, and this fillingneedle 4 provides flow path so that liquid flows toreservoir 2 from tube 3.Tube 3 and reservoir are respectively arranged withbarrier film 6 and 10 in the embodiment in figure 1, and this barrier film must be filledpin 4 and penetrate so that produce flow path between twounit.Filling needle 4 is connected to separateswalls 8 in the mode that can not discharge and remains in the resting position with respect toshell 1 along the central axis ofshell 1.
Filling device also is provided with rotatingpart 7, and this rotating part forms turntable according to this embodiment, and this turntable is provided with flanging at periphery.This flanging provides the contact surface that can slide along the inner surface ofshell 1wall.Rotating part 7 can be around fillingneedle 4 rotations, and this filling needle is immobilized with respect toshell 1 according to this embodiment.
Employing prevents one or moreledge 12 that rotatingpart 7 moves towards tube and prevents that theseparates walls 8 that rotatingpart 7 moves towardsreservoir 2 from preventing that rotatingpart 7 from moving along the longitudinal direction.
Gas can pass to opposite side from a side of rotating part by dischargingpin 5, and by penetratingmember 5a andvalve member 5b constitutes, these two parts connect this discharging crown according to this embodiment.Penetratemember 5a be connected to rotatingpart 7 in the mode that can not discharge and flow path is provided so as gas by rotatingpart 7 and enter theinner room 11 of tube 3 cleaning.Penetratemember 5a and will be provided with end towards the point of tube usually so that it can pierce through the membrane layer 6 of the inlet of protection tube 3.
Rotatingpart 7 is provided with one or morefrictional layer 9 according to this embodiment towards the sidepiece of tube 3.Frictional layer 9 is corresponding to the contact surface on the tube 3 13, and whenfrictional layer 9 contacts with contact surface, and these two unit are " locking " and move together relative to each other.
Fig. 1 also illustrates thereservoir 2 when reservoir is shifted onto in the position ofshell 1 by halfway, and in this halfway position, fillingneedle 4 is the film or thebarrier film 10 of the inlet of pierce through theprotection reservoir 2 not.Reservoir 2 according to this embodiment also is provided with example piston, and during the using and empty ofreservoir 2, liquid is pushed outreservoir 2 by this piston.When the liquid filling reservoir used from tube 3,retract piston 14, inreservoir 2, cause the pressure that reduces, and this pressure that reduces flow path that will provide by fillingneedle 4 the liquid transport that comprises in the tube in reservoir 2.Liquid will reduce the pressure of tube 3 from removing of tube 2 (this is the closed container with rigid walls), if and do not allow air or other gas enter in tube 3 the inner room, then will be necessary to guaranteepiston 14 towards the inwall tight seal ofreservoir 2 so that the pressure that reduces that can overcome the low pressure in the tube 3 can be provided.
Replace the quality that increasesreservoir piston 2, may be more easily, prevent that the pressure in the tube 3 from dropping to low pressure, and, for example, as what propose according to the present embodiment of filling device, by allowing air or other gas enter tube, can realize this target by dischargingpin 5.
Fig. 2 illustrates another embodiment according to filling device of the present invention.According to this embodiment, penetratemember 5a anddrain valve 5b is separated from one another.Drain valve 5a with gas or air from the outside ofshell 1 is delivered toclean room 11 between rotatingpart 7 and the separates walls 8.According to this embodiment, rotatingpart 7 must provide the gas-tight seal to the wall of shell 1.Penetratingmember 5a has towards the blunt end ofreservoir 2 with towards the end of the membranous point of tube 3.When tube 3 is pulled in the appropriate location, penetratesmember 5a and will penetrate barrier film 6 and be formed on the flow path that is provided for clean air/air betweenclean room 11 between rotatingpart 7 and theseparates walls 8 and tube 3 the interior clean room 11.When pressure in thereservoir 2 is reduced, gas will flow through this flow path.
Among the embodiment as Fig. 1, fillingneedle 4 is provided with the end of two points, and when tube 3 andreservoir 2 were pulled in their positions separately, the end of these two points penetrated the barrier film 6 of tube 3 and thebarrier film 10 ofreservoir 2 respectively.
Especially according to the embodiment that has the Fig. 2 that cleans atmosphere in the chamber that is necessary between rotatingpart 7 and separateswalls 8,shell 1 according to filling device of the present invention needs not be columnar or has circular contour, but it should provide between the inner surface of rotatingpart 7 andshell 1 and closely cooperates.If the inner surface of shell is not round in this position, then it can be provided with round track, and for example, this track forms in the ledge of the inner surface of the wall ofshell 1.
The liquid that comprises in the tube will be a kind of medicine usually, and this medicine advantageously can be applied to patient continuously.This medicine can for example be an insulin, and this insulin can be applied to the patient with diabetes with even reading.In this case, tube 3 can be the glass ampule that comprises the insulin of sendout.
Claims (13)
1. filling device, described filling device comprises:
Shell (1), described shell comprises:
First positioner, described first positioner are suitable for admitting the reservoir (2) that is used for admitting liquid;
Second positioner, described second positioner are suitable for admitting the tube (3) that comprises liquid;
Unit (4), described unit is connected to described shell (1) in the mode that can not discharge, and provides flow path when described reservoir (2) and described tube are admitted by described first positioner and second positioner respectively;
Exhaust unit (5,5a, 5b), and during the emptying of described tube (3), the path that described exhaust unit provides gas to arrive described tube (3), and at least a portion of described exhaust unit (5) is arranged to leave the center of rotation (r of described shellc) and be connected to parts (7), it is characterized in that these parts (7) can be with respect to described shell (1) and with respect to described unit (4) rotation that flow path is provided.
2. according to the filling device of claim 1, wherein, when described tube is set according to described second positioner, provide the described unit (4) of the described flow path between described reservoir (2) and the described tube to comprise the pin of end with two points.
3. according to the filling device of claim 1 or 2, wherein, provide the described unit (4) of described flow path along the center of rotation setting of described shell (1).
4. according to the filling device of claim 3, wherein, described unit (4) is secured to the wall (7) in the described shell (1) or the part of the wall in the described shell in the mode that can not discharge, and described wall (7) makes described first positioner that is suitable for admitting described reservoir (2) and is suitable for admitting described second positioner of described tube (3) to separate.
5. according to the filling device of aforementioned arbitrary claim, wherein, can form circular slab with respect to the described parts (7) of described shell (1) rotation, the periphery of described circular slab is close to the wall of described shell (1) or slidably contacts with the wall of described shell (1).
6. according to the filling device of claim 5, wherein, move in the track of described circular slab in the wall that is formed on described shell (1).
7. according to the filling device of claim 5, wherein, the periphery of described circular slab (7) is provided with the track that forms along described periphery, and described track is corresponding to one or more ledge of described shell (1).
8. according to the filling device of each claim among the claim 5-7, wherein, described circular slab (7) is provided with frictional layer (9), and described frictional layer (9) prevents that described tube (3) is mobile with respect to described circular slab (7).
9. according to the filling device of aforementioned arbitrary claim, wherein, described exhaust unit (5) comprises discharging pin (5a), and described discharging pin provides the path from described tube (3) outside to the inner room of described tube (3) during use.
10. according to the filling device of claim 9, wherein, described exhaust unit (5) comprises drain valve (5b), and described drain valve is provided to the half-duplex channel of the clean air in the chamber, supplies described discharging pin (5a) from this chamber with clean air.
11. filling device according to claim 10, wherein, described discharging pin (5a) is connected to described rotating part (7), provide the flow path that is used for clean air, and described drain valve (5b) is connected to the end of opening of the described discharging pin (5a) that points to away from described tube (3) from a side of described rotating part to opposite side.
12. filling device according to claim 10, wherein, discharging pin (5a) is connected to described rotating part (7), the flow path that is used for clean air from a side of described rotating part to opposite side is provided, and described drain valve (5b) is connected to the wall of described shell (1), provides from the wall outside of described shell to the path of the clean air of the inside of the wall of described shell (1).
13. in conjunction with according to the filling device of each claim among the claim 1-11 with comprise the tool set of the tube (3) of liquid, therefore described filling device can be disposable and be permanently connected to described tube (3), or nonexpondable and therefore can be connected to described tube (3) and break away from from described tube (3) and be connected.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5758008P | 2008-05-30 | 2008-05-30 | |
| DKPA200800737 | 2008-05-30 | ||
| DKPA200800737 | 2008-05-30 | ||
| US61/057,580 | 2008-05-30 | ||
| PCT/EP2009/056533WO2009144272A1 (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102202636Atrue CN102202636A (en) | 2011-09-28 |
Family
ID=40194608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009801244405APendingCN102202636A (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110168294A1 (en) |
| EP (1) | EP2303220A1 (en) |
| CN (1) | CN102202636A (en) |
| MX (1) | MX2010013084A (en) |
| WO (1) | WO2009144272A1 (en) |
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| CN113226566A (en)* | 2018-11-26 | 2021-08-06 | 分配技术有限公司 | System and method for dispensing a mixture of a liquid and an additive and cartridge for use therein |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2009144272A1 (en) | 2009-12-03 |
| US20110168294A1 (en) | 2011-07-14 |
| EP2303220A1 (en) | 2011-04-06 |
| MX2010013084A (en) | 2010-12-20 |
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