CN101995454A - A detection device and method of use thereof - Google Patents

Abstract

The present invention relates to a test device comprising a test chamber containing a test element for determining whether an analyte is present in a sample, and an indicator element for indicating whether the test is activated. The invention also relates to a use method of the detection device, which comprises the following steps: collecting a liquid sample; observing the indicating element and determining whether the detection is activated; and (6) detecting. The invention has the beneficial effects that: the position change of the transfer cavity can be effectively protected, the operation is very easy when the detection is activated, and in addition, the signal can be displayed after the detection is activated, so that the detection timing and judgment are convenient.

Description

Translated fromChinese

一种检测装置及其使用方法A detection device and method of use thereof

技术领域technical field

本发明涉及一种检测装置，尤其是一种检测违禁药品的检测装置。The invention relates to a detection device, in particular to a detection device for detecting contraband drugs.

背景技术Background technique

目前，普通民众得到违禁药越来越容易，因此违禁药的使用也越来越多。为了保证工作环境的安全及体育的公平竞争，企业、单位和体育组织需要检测员工、运动员的体液例如尿，以了解员工和运动员是否使用了违禁药。因此体液样本收集检测装置用的越来越多，而且需要在普通场合由非专业人员操作。使用传统的液体样本收集检测装置，存在液体量不能准确定量而产生对检测结果有影响的情况，不能满足液体样本的精确定量或者微量操作时的要求。At present, it is easier and easier for ordinary people to obtain illegal drugs, so the use of illegal drugs is also increasing. In order to ensure the safety of the working environment and the fair competition of sports, enterprises, units and sports organizations need to test the body fluids of employees and athletes, such as urine, to know whether employees and athletes have used illegal drugs. Therefore, more and more body fluid sample collection and detection devices are used, and they need to be operated by non-professionals in common situations. Using the traditional liquid sample collection and detection device, there is a situation that the amount of liquid cannot be accurately quantified, which will affect the test results, and cannot meet the requirements of precise quantification of liquid samples or micro-operation.

美国专利US 6372515公开了一个样本收集检测装置，该装置包括一个收集尿样的尿样杯，和带有多条检测条的检测卡，检测条用来检测尿样。使用时，将检测卡插入尿样杯，让检测条与尿样接触，这样检测可以在几分钟内完成。检测完成以后，尿样杯里的尿样即被检测试剂条里的材料污染，不能完成专业人员进行的二次确认验证。U.S. Patent No. 6,372,515 discloses a sample collection and detection device, which includes a urine sample cup for collecting urine samples, and a test card with a plurality of test strips, which are used to detect urine samples. When using, insert the test card into the urine sample cup, let the test strip contact the urine sample, so that the test can be completed in a few minutes. After the test is completed, the urine sample in the urine sample cup is contaminated by the material in the test reagent strip, and the secondary confirmation verification by professionals cannot be completed.

ZL 200420107950.6公开了一个体液样本检测装置，通过设置杯身底部具有的一端开口的活塞孔，以及与杯腔相通的通孔和与插槽相通的通孔进行液体样本的转移，实现定量检测。在这篇已经公开的实用新型中，包括第一通孔和第二通孔，但该方式在试剂操作过程中容易引起活塞孔中的环形槽滞留气泡和样本，导致定量检测的误差引起结果不准确。ZL 200420107950.6 discloses a body fluid sample detection device, which realizes quantitative detection by setting a piston hole with one end open at the bottom of the cup body, a through hole communicating with the cup cavity and a through hole communicating with the slot for liquid sample transfer. In this disclosed utility model, the first through hole and the second through hole are included, but this method is likely to cause air bubbles and samples to be trapped in the annular groove in the piston hole during the reagent operation process, resulting in errors in quantitative detection and inaccurate results. precise.

ZL 200720303101.1公开了一种液体样本收集检测装置，该检测装置包括收集腔，检测腔和转移腔，转移腔通过至少两个通孔分别与收集腔和检测腔相连，其中至少一个通孔的开口两端位于转移腔的最高位置或者最低位置的两侧。该专利通过改变液体样本检测装置内部的通孔位置来解决在普通的检测装置中存在的因为液体流速过大而产生的气泡从而导致液体样本的流动拥堵和用于检测样本的量不够的问题。ZL 200720303101.1 discloses a liquid sample collection and detection device, the detection device includes a collection chamber, a detection chamber and a transfer chamber, the transfer chamber is connected to the collection chamber and the detection chamber through at least two through holes, wherein at least one through hole has two openings The ends are located on both sides of the highest position or the lowest position of the transfer chamber. This patent solves the problem of flow congestion of liquid samples and insufficient sample volume for detection in common detection devices by changing the position of the through holes inside the liquid sample detection device due to bubbles generated due to excessive liquid flow velocity.

发明内容Contents of the invention

本发明涉及一种检测装置，包括容纳分析样本中是否含有被分析物质的检测元件的检测腔，以及一个显示检测是否被激活的指示元件。这种指示元件，一方面，主要显示检测元件是否被使用过，当有液体样本存在的情况下，指示元件指示检测元件已经被使用了，说明检测已经被激活了。另外，假如在检测之前，就获得指示元件发出的检测被激活的信号，则说明检测装置被误操作过，这样的检测装置和检测元件视为被使用过，同时也视为检测被激活了，不能用于检测了。优选的，检测装置还包括还包括将液体样本转移到检测腔的转移腔。更为优选的，检测装置还包括用于收集液体样本的收集腔，转移腔连接收集腔和检测腔。对于这种带有转移腔的检测装置，尤其是依赖转移腔将液体样本从收集腔转移到检测腔的检测装置，需要通过转移腔位置的改变来实现液体样本的转移。在一个具体的实施例中，转移腔的位置改变通过一个推动部件来实现，其中，如果转移腔中的液体样本已经转移到检测腔中，我们可以通过一个显示检测被激活的指示元件获得信息，此时，液体样本同检测腔中的检测试剂条接触，激活并启动检测反应。优选的，该指示元件跟随转移腔的移动而移动，这种方式，可以比较直观得反应转移腔的位置移动，从而比较清楚的表明检测是否被激活。更为优选的，检测装置还包括一个观察窗口，用于观察指示元件，获得检测是否被激活的信号。另外，本发明还涉及一个推动部件，该推动部件可以激活转移腔到检测腔的液体流动，而且，该推动部件还包括一个在检测被激活前与推动部件连接在一起的阻挡元件。这种阻挡元件，可以阻止在检测被激活前推动部件的异常推动，比如在生产装配过程，在运输过程，在被检测者收集样本过程和其他过程中，如果没有阻挡元件的暂时“保护”作用，引起在异常推动，将使整个检测装置处于无法工作状态，这对于快速诊断检测是不利的。另外优选的，这种在检测被激活前与推动部件连为一体的阻挡元件，可以在激活检测前，从推动部件上剥落下来。The invention relates to a detection device, which includes a detection chamber containing a detection element for analyzing whether a sample contains an analyte, and an indicator element for displaying whether the detection is activated. This indicator element, on the one hand, mainly displays whether the detection element has been used. When there is a liquid sample, the indicator element indicates that the detection element has been used, indicating that the detection has been activated. In addition, if the detection activated signal from the indicating element is obtained before the detection, it indicates that the detection device has been misoperated. Such a detection device and detection element are deemed to have been used, and at the same time, the detection is activated. Cannot be used for testing. Preferably, the detection device further includes a transfer chamber for transferring the liquid sample to the detection chamber. More preferably, the detection device further includes a collection chamber for collecting liquid samples, and the transfer chamber is connected to the collection chamber and the detection chamber. For such a detection device with a transfer chamber, especially a detection device that relies on the transfer chamber to transfer the liquid sample from the collection chamber to the detection chamber, it is necessary to change the position of the transfer chamber to realize the transfer of the liquid sample. In a specific embodiment, the position change of the transfer chamber is realized by a push member, wherein, if the liquid sample in the transfer chamber has been transferred into the detection chamber, we can obtain information through an indicator element showing that the detection is activated, At this time, the liquid sample is in contact with the detection reagent strip in the detection chamber to activate and start the detection reaction. Preferably, the indicating element moves with the movement of the transfer chamber. In this way, the position of the reaction transfer chamber can be observed more intuitively, so as to clearly indicate whether the detection is activated. More preferably, the detection device further includes an observation window for observing the indicating element to obtain a signal of whether the detection is activated. In addition, the present invention also relates to a pushing part, which can activate the liquid flow from the transfer chamber to the detection chamber, and the pushing part also includes a blocking element connected with the pushing part before the detection is activated. This blocking element can prevent the abnormal pushing of the pushing part before the detection is activated, such as during the production assembly process, during the transportation process, during the collection of samples by the tested person and other processes, if there is no temporary "protection" effect of the blocking element , causing an abnormal push, will make the entire detection device in an inoperable state, which is unfavorable for rapid diagnostic detection. In addition, preferably, the blocking element, which is integrated with the pushing part before the detection is activated, can be peeled off from the pushing part before the detection is activated.

本发明还涉及检测装置100的使用方法：收集液体样本；观察指示元件8并判断检测是否被激活；检测。优选的，检测装置100还包括将液体样本转移到检测腔32的转移腔22，指示元件8位于转移腔22并随着转移腔22的位置改变而改变位置。其使用方法包括：收集液体样本；推动转移腔22使液体样本从转移腔22流到检测腔32，其中指示元件8随着转移腔22的移动而移动；观察指示元件8并判断激活检测；检测。The present invention also relates to a method of using the detection device 100: collecting a liquid sample; observing the indicatingelement 8 and judging whether the detection is activated; detection. Preferably, the detection device 100 further includes atransfer chamber 22 for transferring the liquid sample to the detection chamber 32 , and the indicatingelement 8 is located in thetransfer chamber 22 and changes position as the position of thetransfer chamber 22 changes. Its use method includes: collecting liquid samples; pushing thetransfer chamber 22 to make the liquid samples flow from thetransfer chamber 22 to the detection chamber 32, wherein the indicatingelement 8 moves with the movement of thetransferring chamber 22; observing the indicatingelement 8 and judging activation detection; detecting .

本发明的有益效果是：能有效得保护转移腔的位置改变，并且在检测激活时非常容易操作，另外，在检测被激活后可以显示信号，便于进行检测计时和判断。The beneficial effects of the invention are: it can effectively protect the position change of the transfer cavity, and it is very easy to operate when the detection is activated; in addition, after the detection is activated, a signal can be displayed, which is convenient for detection timing and judgment.

附图说明Description of drawings

图1为本发明一具体实施例的立体图；Fig. 1 is the perspective view of a specific embodiment of the present invention;

图2为本发明一具体实施例的正面示意图；Fig. 2 is the front schematic diagram of a specific embodiment of the present invention;

图3为本发明一具体实施例的爆炸分解图；Figure 3 is an exploded exploded view of a specific embodiment of the present invention;

图4为本发明一具体实施例在检测前的状态示意图；Fig. 4 is a schematic diagram of a state before detection of a specific embodiment of the present invention;

图5为本发明一具体实施例在检测时和检测后的状态示意图。Fig. 5 is a schematic diagram of a state during and after detection of a specific embodiment of the present invention.

附图标记说明：检测装置(尿杯)100；杯盖1；杯身2，杯口20，杯口螺纹201，收集腔21，活塞孔(转移腔)22，活塞23，橡皮圈24，活塞孔开口25，开放环形槽26，上通孔27，下通孔28，活塞孔29；杯座3，吸水纸31，检测腔32，支撑条33，插槽34；密封圈4；测试卡(检测卡)5，检测结果显示区51，检测试剂条条52，插板53，插板开口54，不干胶窗口55，插板突起56；推动部件6，推柄60，阻挡环61、63，拿捏处62；封闭环形槽7；指示元件8。Explanation of reference signs: detection device (urine cup) 100;cup cover 1;cup body 2,cup mouth 20,cup mouth thread 201,collection chamber 21, piston hole (transfer chamber) 22, piston 23,rubber ring 24, piston Hole opening 25, openannular groove 26, upper throughhole 27, lower throughhole 28, piston hole 29;cup holder 3,absorbent paper 31, detection cavity 32,support bar 33,slot 34;sealing ring 4; test card ( Detection card) 5, detectionresult display area 51,detection reagent strip 52,insert plate 53, insert plate opening 54, self-adhesive window 55,insert plate protrusion 56; pushingpart 6,push handle 60,blocking rings 61, 63 , Knead at 62; closedannular groove 7; indicatingelement 8.

具体实施方式Detailed ways

下面对检测装置的结构或这些所使用的技术术语做进一步的说明。The structure of the detection device or the technical terms used will be further explained below.

检测表示化验或测试一种物质或材料是否存在，比如，但并不限于此，化学物质、有机化合物、无机化合物、新陈代谢产物、药物或者药物代谢物、有机组织或有机组织的代谢物、核酸、蛋白质或聚合物。另外，检测表示测试物质或材料的数量。进一步说，化验还表示免疫检测，化学检测、酶检测等。To detect means to assay or test for the presence of a substance or material such as, but not limited to, a chemical substance, an organic compound, an inorganic compound, a metabolic product, a drug or a drug metabolite, an organic tissue or a metabolite of an organic tissue, a nucleic acid, protein or polymer. Additionally, detection means the amount of a substance or material tested. Further, assay also means immunoassay, chemical assay, enzyme assay, etc.

本发明所指的样本指那些可以用来检测、化验或诊断是否存在感兴趣的被分析物质的物质。样本可以是，例如，液体样本，液体样本可以包括血液、血浆、血清、尿液、唾液和各种分泌液，还可以包括固体样本和半固体样本经过预先处理后形成的液体溶液。收集来的样本可以用于免疫检测、化学检测、酶检测等方法来检测是否存在被分析物质。The samples referred to in the present invention refer to those substances that can be used to detect, assay or diagnose the presence or absence of the analyte of interest. The sample can be, for example, a liquid sample, and the liquid sample can include blood, plasma, serum, urine, saliva and various secretions, and can also include a liquid solution formed after pretreatment of solid samples and semi-solid samples. The collected samples can be used for immunological detection, chemical detection, enzyme detection and other methods to detect the presence of the analyte.

用本发明的装置和方法可以分析任何被分析物质。能够用本发明的装置和方法稳定检测的被分析物的例子包括(但是不仅仅包括)人绒毛膜促性腺激素(hCG)，黄体生成素(LH)，卵巢刺激素(FSH)，丙肝病毒(HCV)，乙肝病毒(HBV)，乙肝表面抗原，艾滋病病毒和任何滥用的药物。被分析物能够在任何的液体或者液化样品中检测到，例如尿液，唾液，口水，血液，血浆，或者血清。其它的被分析物的例子还有肌氨酐酸，胆红素，亚硝酸盐，蛋白质(非特异性的)，血液，白细胞，血糖，重金属和毒素，细菌成分(例如，特定类型的细菌的特殊的蛋白质和糖分，任何其它的适合侧流试验形式的被分析物都可以用本装置检测。Any analyte can be analyzed using the device and method of the present invention. Examples of analytes that can be stably detected by the devices and methods of the present invention include (but not exclusively) human chorionic gonadotropin (hCG), luteinizing hormone (LH), ovarian stimulating hormone (FSH), hepatitis C virus ( HCV), hepatitis B virus (HBV), hepatitis B surface antigen, HIV and any drug of abuse. Analytes can be detected in any liquid or liquefied sample, such as urine, saliva, saliva, blood, plasma, or serum. Other examples of analytes are creatinine, bilirubin, nitrite, proteins (non-specific), blood, leukocytes, glucose, heavy metals and toxins, bacterial components (e.g., specific Proteins and sugars, any other analyte suitable for lateral flow test format can be detected by this device.

被分析物质还可以是一些半抗原物质，这些半抗原包括毒品(如滥用药物)。“滥用药物”(DOA)是指非医学目的地使用药品(通常起麻痹神经的作用)。滥用这些药物会导致身体和精神受到损害，产生依赖性、上瘾并且/或者死亡。药物滥用的例子包括可卡因；安非他明(例如，黑美人、白色安非他命药片、右旋安非他命、右旋苯异丙胺药片、Beans)；甲基苯丙胺(crank、甲安菲他明、crystal，speed)；巴比妥酸盐(如Valium，Roche Pharmaceuticals，Nutley，New Jersey)；镇静剂(即睡觉辅助药品)；麦角酸酰二乙胺(LSD)；抑制剂(downers，goofballs，barbs，blue devils，yellow jackets，安眠酮)；三环类抗抗抑郁剂(TCA，即丙咪嗪、阿密曲替林和多虑平)；苯环己哌啶(PCP)；四氢大麻醇(THC、pot，dope，hash，weed，等。)；鸦片制剂(即吗啡、鸦片、可待因、海洛因，羟二氢可待因酮)；抗焦虑药与镇静催眠药，抗焦虑药是一类主要用于减轻焦虑、紧张、恐惧，稳定情绪，兼有催眠镇静作用的药物，包括苯二氮卓类(benzodiazepines，BZ)、非典型BZ类、融合二氮NB23C类、苯氮卓类、BZ受体的配体类、开环BZ类、二苯甲烷衍生物、哌嗪羧酸盐类、哌啶羧酸盐类、奎唑啉酮类、噻嗪及噻唑衍生物、其他杂环类、咪唑型镇静/止痛药、丙二醇衍生物-氨甲酸酯类、脂肪族化合物、蒽类衍生物等。使用该装置也可以用于检测属于医学用途但又容易服药过量的检测，如三环类抗抑郁药(丙米嗪或类似物)和乙酰氨基酚等。这些药品被人体吸收后会分解成不同的小分子物质，这些小分子物质存在于血液、尿液、唾液、汗水等体液中或部分体液存在上述小分子物质。The analytes may also be hapten substances including drugs (eg drugs of abuse). "Drugs of Abuse" (DOA) refers to the use of drugs (usually to paralyze the nerves) for non-medical purposes. Abuse of these drugs can lead to physical and mental impairment, dependence, addiction and/or death. Examples of drugs of abuse include cocaine; amphetamines (e.g., Black Beauty, White Amphetamine Tablets, Dextroamphetamine, Dextroamphetamine Tablets, Beans); methamphetamines (crank, methamphetamine, crystal, speed ); barbiturates (eg, Valium, Roche Pharmaceuticals, Nutley, New Jersey); sedatives (ie, sleep aids); lysergic acid diethylamide (LSD); depressants (downers, goofballs, barbs, blue devils, yellow jackets, methaphene); tricyclic antidepressants (TCA, i.e., imipramine, amitriptyline, and doxepin); phencyclidine (PCP); tetrahydrocannabinol (THC, pot , dope, hash, weed, etc.); opiates (ie morphine, opium, codeine, heroin, oxydihydrocodone); anxiolytics and sedative hypnotics, anxiolytics are a class of mainly used Drugs that are used to reduce anxiety, tension, fear, stabilize emotions, and have hypnotic and sedative effects, including benzodiazepines (BZ), atypical BZs, fusion diazepines NB23Cs, benzodiazepines, and BZ receptors Ligands, ring-opening BZs, diphenylmethane derivatives, piperazine carboxylates, piperidine carboxylates, quinazolones, thiazine and thiazole derivatives, other heterocycles, imidazoles Sedative/painkillers, propylene glycol derivatives-carbamates, aliphatic compounds, anthracene derivatives, etc. The device can also be used to detect drugs that are medically used but prone to overdose, such as tricyclic antidepressants (imipramine or similar) and acetaminophen. These medicines will be decomposed into different small molecular substances after being absorbed by the human body. These small molecular substances exist in blood, urine, saliva, sweat and other body fluids or some of the above-mentioned small molecular substances exist in body fluids.

检测装置Detection device

本发明涉及的检测装置100，包括容纳分析样本中是否含有被分析物质的检测元件5的检测腔32。检测装置100可以由多种不同形状和不同材料制成，例如各种规格的塑料。The detection device 100 involved in the present invention includes a detection cavity 32 for accommodating the detection element 5 for analyzing whether the sample contains the analyte. The detection device 100 can be made of many different shapes and different materials, such as plastics of various specifications.

在一个具体的实施方式中，检测装置100还包括一个显示检测是否被激活的指示元件8。这种指示元件8，一方面，主要显示检测元件5是否被使用过，当有液体样本存在的情况下，指示元件8指示检测元件5已经被使用了，说明检测已经被激活了。另外一方面，假如在检测之前，就获得指示元件8发出的检测被激活的信号，则说明检测装置100被误操作过，这样的检测装置100和检测元件5视为被使用过，同时也视为检测被激活了，不能用于检测了。所以，检测元件5已经被使用过或者检测装置100被使用过，都是可以被认为是检测被激活过。检测被激活的信号，可以是指示元件8本身，也可以是指示元件8和其他物质起反应形成的信号。这种指示元件8，包括化学指示，比如通过显示颜色的方式。在一个实施例中，可以通过化学物质的反应，比如利用硫氰酸钾和三价铁离子的反应，出现深红色的颜色反应。在另外的实施例中指示元件也可以包括采用食用色素。在另一个实施方案中，所述的指示元件8包括PH剂。在指示区域上载入带有PH剂的材料，比如PH试纸，根据液体样本的PH值不同，尿液的PH值在5-7之间，位于指示区域上的PH试纸接触样本后，由原先的黄色被浸润成草绿色，发生颜色变化，达到指示作用。另外，指示还包括物理指示，在一个实施方案中，所述的指示元件8，可以是一着色材料，该材料至少部分被一基本不透明层所覆盖，当有液体存在时，所述不透明层变得透明清楚从而使所述的着色材料能够被观察到。在另一个实施例中，指示元件8可以是一带颜色的不干胶8，这个不干胶8在检测前是不容易被看到或者隐藏的，在检测被激活以后可以比较清楚得被看到。优选的，检测装置100还包括用于收集液体样本的收集腔21，和将液体样本从收集腔21转移到检测腔32的转移腔22。指示元件8可以位于检测装置的任一位置，如收集腔21、转移腔22或者检测腔32。其中更为优选的，由于转移腔22是检测被激活的关键，所以指示元件8可以位于转移腔22上。在一个具体的实施例中，指示元件8可以位于转移腔22上，并随着转移腔22的位置改变而改变位置。具体的说，在收集液体样本之后，液体样本存在于收集腔21和转移腔22中，此时，推动转移腔22使液体样本进入检测腔32，在检测腔32中，存在着检测元件5，检测元件5的样本吸收部件可以和检测腔32的液体样本检测，从而引发检测。设置这样的指示元件8，如果液体样本已经进入检测腔32，同时也可以迅速判断检测腔32内的检测已经开始，因此，指示元件8在指示液体样本是否从转移腔22流到检测腔32的同时，也指示了检测是否被激活。较佳的，转移腔22包括带有活塞23的活塞孔，活塞23和活塞孔组成了若干环形槽。其中液体样本可以在转移腔22的开放环形槽26中暂存和转移，而指示元件位于封闭环形槽7中。当转移腔22的开放环形槽26被推动部件6向活塞23深处推动时，封闭环形槽7也向活塞23的封闭端移动，当开放环形槽26和检测腔32连通时，指示元件8发出检测被激活的信号。In a specific embodiment, the detection device 100 further includes anindicator element 8 for displaying whether the detection is activated. Thisindicator element 8, on the one hand, mainly displays whether the detection element 5 has been used. When there is a liquid sample, theindicator element 8 indicates that the detection element 5 has been used, indicating that the detection has been activated. On the other hand, if the detection activated signal from theindicator element 8 is obtained before the detection, it means that the detection device 100 has been misoperated. It is activated for detection and cannot be used for detection. Therefore, if the detection element 5 has been used or the detection device 100 has been used, it can be considered that the detection has been activated. The signal for detecting activation may be theindicator element 8 itself, or a signal formed by the reaction between theindicator element 8 and other substances. Such an indicatingelement 8 comprises a chemical indication, for example by displaying a colour. In one embodiment, the deep red color reaction may occur through the reaction of chemicals, such as using potassium thiocyanate and ferric ions. In other embodiments the indicator element may also include the use of food coloring. In another embodiment, said indicatingelement 8 comprises a pH agent. Load materials with pH agents on the indication area, such as pH test paper. According to the pH value of the liquid sample, the pH value of urine is between 5 and 7. After the pH test paper on the indication area touches the sample, the original The yellow color is infiltrated into grass green, and the color changes to achieve the indication function. In addition, indications also include physical indications. In one embodiment, saidindication element 8 may be a colored material at least partially covered by a substantially opaque layer that becomes transparent when a liquid is present. be transparent so that the coloring material can be observed. In another embodiment, the indicatingelement 8 can be a colored self-adhesive 8, the self-adhesive 8 is not easy to be seen or hidden before detection, and can be seen more clearly after the detection is activated . Preferably, the detection device 100 further includes acollection chamber 21 for collecting liquid samples, and atransfer chamber 22 for transferring the liquid samples from thecollection chamber 21 to the detection chamber 32 . The indicatingelement 8 can be located at any position of the detection device, such as thecollection chamber 21 , thetransfer chamber 22 or the detection chamber 32 . Among them, more preferably, since thetransfer chamber 22 is the key to detecting activation, the indicatingelement 8 can be located on thetransfer chamber 22 . In a specific embodiment, the indicatingelement 8 may be located on thetransfer cavity 22 and change its position as the position of thetransfer cavity 22 changes. Specifically, after the liquid sample is collected, the liquid sample exists in thecollection chamber 21 and thetransfer chamber 22. At this time, thetransfer chamber 22 is pushed to make the liquid sample enter the detection chamber 32. In the detection chamber 32, there is a detection element 5, The sample-absorbing part of the detection element 5 can detect with the liquid sample in the detection chamber 32, thereby triggering detection. Such indicatingelement 8 is set, if the liquid sample has entered the detection chamber 32, it can also be quickly judged that the detection in the detection chamber 32 has started, therefore, the indicatingelement 8 is indicating whether the liquid sample flows from thetransfer chamber 22 to the detection chamber 32. At the same time, it also indicates whether the detection is activated. Preferably, thetransfer chamber 22 includes a piston hole with a piston 23, and the piston 23 and the piston hole form several annular grooves. The liquid sample can be temporarily stored and transferred in the openannular groove 26 of thetransfer chamber 22 , while the indicating element is located in the closedannular groove 7 . When the openannular groove 26 of thetransfer chamber 22 is pushed to the depth of the piston 23 by the pushingmember 6, the closedannular groove 7 also moves to the closed end of the piston 23, and when the openannular groove 26 communicates with the detection chamber 32, the indicatingelement 8 emits a signal. Detect activated signal.

更为优选的，检测装置100还包括观察窗口54，是用于观察指示元件显示信号的窗口。这种观察窗口5421，可以位于检测装置的收集腔上，也可以位于转移腔22或者检测腔32或者其他位置。位于检测装置上的观察窗口54，可以是透明的，能较清楚得看到检测被激活时的信号。如透明的检测腔或者转移腔本身就可以作为观察窗口。优选的，观察窗口54可以是检测腔的测试板5上的一个通孔。一般来说，检测装置100是塑料制品，测试板5会设计成白色的插板53形状，在插板53上设置一个通孔54，然后通过这个通孔54可以看到位于转移腔中的指示元件8发出检测开始的信号。更为优选的，在检测未被激活前，指示元件8处于第一位置，当推动部件6推动转移腔22，使转移腔22中的液体样本流到检测腔32后，在推动完成后，指示元件8位于第二位置，这个第二位置正对着检测窗口54，也就是检测板上的通孔54，那么检测装置的操作者可以通过观察窗口55非常清楚得看到指示元件8本身并且获得检测被激活的信号。More preferably, the detection device 100 further includes an observation window 54, which is a window for observing the signal displayed by the indicating element. The observation window 5421 may be located on the collection chamber of the detection device, or may be located on thetransfer chamber 22 or the detection chamber 32 or other locations. The observation window 54 on the detection device can be transparent, so that the signal when the detection is activated can be seen more clearly. For example, a transparent detection chamber or a transfer chamber itself can be used as an observation window. Preferably, the observation window 54 may be a through hole on the test board 5 of the detection chamber. Generally speaking, the detection device 100 is a plastic product, and the test board 5 can be designed in the shape of a white plug-inboard 53, and a through hole 54 is arranged on the plug-inboard 53, and then the indicator located in the transfer chamber can be seen through this through hole 54.Element 8 signals the start of detection. More preferably, before the detection is not activated, the indicatingelement 8 is in the first position. When the pushingmember 6 pushes thetransfer chamber 22 to make the liquid sample in thetransfer chamber 22 flow to the detection chamber 32, after the pushing is completed, theindication Element 8 is positioned at the second position, and this second position is just opposite to detection window 54, just the through hole 54 on the detection plate, so the operator of the detection device can see indicatingelement 8 itself very clearly throughobservation window 55 and obtain Detect activated signal.

在另一个具体实施方式中，检测装置100可以包括一个推动部件6。位于检测腔32的检测元件5，不能自发进行，需要在一个动作下才能被激活，推动部件6可以起到使检测腔32的检测被激活的作用。通过推动部件6的推动或者其他动作，使液体样本进入检测腔32，激发检测液体样本中是否含有被分析物质的检测元件5的反应。检测装置100还可以包括收集液体样本的收集腔21，以及连接收集腔21和检测腔32的转移腔22。推动部件6的作用是使液体样本从转移腔流动到检测腔，并激活检测反应。推动部件6的位置，优选的，和转移腔22的配合使用的。在一个具体的实施例中，推动部件6可以位于杯盖1上，在需要推动的时候，将推动部件6从杯盖1中取出，将转移腔22的一端推动到另外一端，实现转移腔22中液体样本的转移。优选的，推动部件6和转移腔22相连，在使用时直接推动该部件6，方便操作。更为优选的，该推动部件6还包括一个阻挡元件61，62，63。该阻挡元件61，62，63是用于防止推动部件6的异常推动的。具体的说，这种阻挡元件61，62，63，在不需要液体转移的时候，阻止推动部件6的作用；在需要液体转移时，阻挡元件61，62，63可以被解除，从而推动部件6开始起作用。在一个优选的实施例中，阻挡元件61，62，63和推动部件6可以连为一体。所谓的连为一体，确切的说，在检测被激活前，阻挡元件61，62，63和推动部件6是连接在一起的，当需要激活检测的时候，阻挡元件61，62，63可以从推动部件6上剥落下来，然后推动部件6就可以发挥推动转移腔22的作用。在一个更为优选的实施例中，转移腔22为活塞孔，活塞孔22内包括活塞23，阻挡元件61，62，63包裹在活塞23外，推动部件6与活塞23的一端配合。将阻挡元件61，62，63从活塞23外去除，此时，推动部件6可以往前推动而不受阻挡元件61，62，63的限制，推动的过程可以使液体从转移腔22流动到检测腔32，从而激活检测。更为优选的，阻挡元件61，62，63还包括一个可以拿捏的突起62，利用这个拿捏处62，可以非常便捷得将阻挡元件61，63从推动部件6上剥落下来。In another specific embodiment, the detection device 100 may include a pushingmember 6 . The detection element 5 located in the detection cavity 32 cannot be activated spontaneously, and needs to be activated with one action, and the pushingmember 6 can play a role in activating the detection of the detection cavity 32 . The liquid sample enters the detection cavity 32 through the push of thepush member 6 or other actions, and the reaction of the detection element 5 that detects whether the liquid sample contains the analyte is stimulated. The detection device 100 may further include acollection chamber 21 for collecting liquid samples, and atransfer chamber 22 connecting thecollection chamber 21 and the detection chamber 32 . The function of the pushingpart 6 is to make the liquid sample flow from the transfer chamber to the detection chamber and activate the detection reaction. The position of the pushingmember 6 is preferably used in conjunction with thetransfer cavity 22 . In a specific embodiment, the pushingpart 6 can be located on thecup cover 1. When pushing is required, the pushingpart 6 is taken out from thecup cover 1, and one end of thetransfer chamber 22 is pushed to the other end to realize thetransfer chamber 22. transfer of liquid samples. Preferably, the pushingpart 6 is connected to thetransfer chamber 22, and thepart 6 is directly pushed during use, which is convenient for operation. More preferably, the pushingpart 6 further includes a blockingelement 61 , 62 , 63 . The blockingelements 61 , 62 , 63 are used to prevent abnormal pushing of the pushingmember 6 . Specifically,such blocking elements 61, 62, 63 prevent the action of the pushingmember 6 when liquid transfer is not required; start to work. In a preferred embodiment, the blockingelements 61, 62, 63 and the pushingmember 6 can be integrated into one body. The so-called connection, to be precise, before the detection is activated, the blockingelements 61, 62, 63 and the pushingpart 6 are connected together, and when the detection needs to be activated, the blockingelements 61, 62, 63 can be pushed from Thecomponent 6 is peeled off, and then the pushingcomponent 6 can play the role of pushing thetransfer cavity 22 . In a more preferred embodiment, thetransfer cavity 22 is a piston hole, and thepiston hole 22 includes the piston 23 , the blockingelements 61 , 62 , 63 are wrapped around the piston 23 , and the pushingpart 6 is matched with one end of the piston 23 . Remove the blockingelements 61, 62, 63 from the outside of the piston 23. At this time, the pushingmember 6 can be pushed forward without being restricted by the blockingelements 61, 62, 63. The process of pushing can make the liquid flow from thetransfer chamber 22 to the detection chamber 32, thereby activating detection. More preferably, the blockingelements 61 , 62 , 63 also include ahandleable protrusion 62 , and the blockingelements 61 , 63 can be easily peeled off from the pushingmember 6 by using thehandle 62 .

以上优选的，检测装置100还可以包括用于收集液体样本的收集腔21，含有测试卡5的检测腔32和将液体样本从收集腔21转移到检测腔32的转移腔22。Preferably, the detection device 100 may further include acollection chamber 21 for collecting liquid samples, a detection chamber 32 containing the test card 5 and atransfer chamber 22 for transferring the liquid sample from thecollection chamber 21 to the detection chamber 32 .

收集腔21的腔体可以采用任何形状，比如圆柱形，类似注射器形，烟囱形，或者其他可用于储存液体的任何形式。收集腔21可以由杯身2，杯口20和杯盖1组成。杯口20和杯盖1可以通过密封来保证液体在杯身2中盛放而不泄漏出来。杯口20和杯盖1的密封形式可以有多种，比如杯口20和杯盖1可以有互相配合的螺纹20，通过旋转的方式达到密封的效果。更佳的，还可以在杯盖1内设置有密封圈4，通过密封圈4和杯口20的杯沿的作用对装置起到密封作用。The cavity of thecollection cavity 21 can be in any shape, such as cylindrical, similar to a syringe, chimney, or any other form that can be used to store liquid. The collectingcavity 21 can be composed of thecup body 2 , thecup mouth 20 and thecup cover 1 . Thecup mouth 20 and thecup lid 1 can be sealed to ensure that the liquid is contained in thecup body 2 without leaking out. The sealing form of thecup mouth 20 and thecup lid 1 can be various, for example, thecup mouth 20 and thebowl lid 1 can havethreads 20 that cooperate with each other, and the sealing effect can be achieved by rotating. More preferably, a sealingring 4 can also be provided in thecup cover 1, and the device can be sealed through the function of the sealingring 4 and the edge of thecup mouth 20 .

检测腔32可以包括杯座3和测试卡5。杯座3的作用是支撑整个检测装置处于平衡状态。杯座3的底部还可以包括有吸水材料31和插槽，吸水纸31可以吸收插槽34中多余的液体，使得液体不会从杯座3中漏出来而污染环境。插槽34内可以插有检测元件5，用于检测液体样本中是否含有被分析物质。插槽34内还有支撑条33，用于支撑测试卡5上的插板突起56，使带有带测试条的测试卡5略微悬空于杯座的插槽34，这样的好处在于，在检测试剂条52吸收液体样本的过程中，检测试剂条52可以一直保持直立状态，不会因为弯曲而导致影响检测结果的目的。检测元件5可以选用横向流动的检测试纸条52，也可以是带有若干检测试剂条的插板53。各种检测元件5可以被组合一起运用到本发明中。一种形式是检测试纸，另一种形式可以是一些试剂，如与被分析物特异性结合的分子被固定在检测区。这些试剂与样品中的被分析物(如果存在)反应并将被分析物结合在该区，或者与实际区的某一个试剂结合，用于显示检测信号的标记物质与试剂区或分离的标记区。这些检测试剂条或者检测试剂都是本领域技术人员熟悉的常规测试手段。The detection chamber 32 may include acup holder 3 and a test card 5 . The function of thecup holder 3 is to support the whole detection device in a balanced state. The bottom of thecup holder 3 can also include a water-absorbingmaterial 31 and a slot, and theabsorbent paper 31 can absorb excess liquid in theslot 34, so that the liquid will not leak out of thecup holder 3 and pollute the environment. A detection element 5 can be inserted into theslot 34 for detecting whether the liquid sample contains the analyte. There is also asupport bar 33 in theslot 34, which is used to support theinsertion plate protrusion 56 on the test card 5, so that the test card 5 with the test strip is slightly suspended in theslot 34 of the cup holder. During the process of thereagent strip 52 absorbing the liquid sample, thedetection reagent strip 52 can always maintain an upright state, and will not affect the detection result due to bending. The detection element 5 can be adetection test strip 52 with lateral flow, or aninsert plate 53 with several detection reagent strips. Various detection elements 5 can be used in combination in the present invention. One form is a test strip, and the other form can be that some reagents, such as molecules that specifically bind to the analyte, are immobilized in the detection area. These reagents react with the analyte (if present) in the sample and bind the analyte in the zone, or bind to a reagent in the actual zone, the labeling substance used to show the detection signal and the reagent zone or a separate labeling zone . These detection reagent strips or detection reagents are conventional testing means familiar to those skilled in the art.

转移腔22是位于收集腔21和检测腔32之间并且能将液体从一个腔转移到另一个腔的部件。转移腔22与收集腔21或者检测腔32之间可以是交界的，拥有共同的壁。转移腔22可以是一个受控制的开口，当打开开口，液体就可以顺着开口流动到另外一个腔。转移腔22也可以是一个双向的阀门，扭动阀门可以使两个腔之间的液体进行流通。转移腔22还可以是一个活塞孔，通过活塞23的位置变动将收集腔21中的液体转移到检测腔32中，这种转移腔22的优点在于液体样本单向流动，不会造成检测腔32中已经过检测的而被检测试剂污染的液体进入收集腔21，相当于说，收集腔21中的液体是不受污染的，可以用于二次测试或者鉴定。转移腔22上可以包括一些通孔，其中有上通孔27与收集腔21相连，下通孔28与检测腔32相连。更佳的，当上通孔27与收集腔21相连的时候，转移腔22和收集腔21处于液体流通状态，而转移腔22和检测腔32处于液体不流通状态。同样，当转移腔22通过下通孔28与检测腔32相通的时候，转移腔22和收集腔21处于液体不能流通状态。这样设计有利于实现收集腔21和检测腔32之间的液体转移，又不会使液体在收集腔21和检测腔32之间自由流动。转移腔22可以内置活塞23，活塞23和活塞孔22呈滑动密封配合。活塞23的前端还可以具有空槽，该空槽可以通过上通孔27与收集腔21相连通，还可以通过下通孔28与检测腔32相连通。上通孔27和下通孔28不能同时和空槽相连通。空槽的形状可以是环形，方形，也可以是其他规则或者不规则的形状。活塞23可以经由操作者的手指或者其他器具，如推动部件来改变活塞23在活塞孔22中的位置，来达到将液体转移的目的。在转移腔22中，可以由活塞23和活塞孔22以及橡皮圈24形成若干个环形槽，如供液体转移的开放环形槽26和封闭环形槽7。以开放环形槽26为例，处于最初状态的时候，开放环形槽26借助上通孔27和收集腔21相通，当收集腔21中存在液体样本的时候，液体能通过上通孔27进入开放环形槽26。推动活塞23使开放环形槽26和上通孔27处于不相连状态，而与下通孔28相通的时候，开放环形槽26中的液体样本可以通过下通孔28流入检测腔32，从而启动检测反应，对液体样本中是否存在被分析物进行检测。本发明还可以通过开放环形槽26的大小来对转移液体进行定量。Thetransfer chamber 22 is a component located between thecollection chamber 21 and the detection chamber 32 and capable of transferring liquid from one chamber to the other. Thetransfer chamber 22 may be bordered with thecollection chamber 21 or the detection chamber 32 and share a common wall. Thetransfer chamber 22 can be a controlled opening, when the opening is opened, the liquid can flow to another chamber along the opening. Thetransfer chamber 22 can also be a two-way valve, twisting the valve can make the liquid between the two chambers communicate. Thetransfer chamber 22 can also be a piston hole, and the liquid in thecollection chamber 21 is transferred to the detection chamber 32 through the position change of the piston 23. The advantage of thistransfer chamber 22 is that the liquid sample flows in one direction without causing the detection chamber 32 The liquid that has been tested and contaminated by the detection reagent enters thecollection chamber 21, which means that the liquid in thecollection chamber 21 is free from contamination and can be used for secondary testing or identification. Thetransfer chamber 22 may include some through holes, wherein an upper throughhole 27 is connected to thecollection chamber 21 , and a lower throughhole 28 is connected to the detection chamber 32 . More preferably, when the upper throughhole 27 is connected to thecollection chamber 21, thetransfer chamber 22 and thecollection chamber 21 are in a state of liquid communication, while thetransfer chamber 22 and the detection chamber 32 are in a state of liquid non-flow. Similarly, when thetransfer chamber 22 communicates with the detection chamber 32 through the lower throughhole 28 , thetransfer chamber 22 and thecollection chamber 21 are in a state where liquid cannot communicate. Such a design is beneficial to achieve liquid transfer between thecollection chamber 21 and the detection chamber 32 , and does not allow the liquid to flow freely between thecollection chamber 21 and the detection chamber 32 . Thetransfer chamber 22 may have a built-in piston 23, and the piston 23 and thepiston hole 22 are in a sliding and sealing fit. The front end of the piston 23 can also have an empty groove, which can communicate with thecollection chamber 21 through the upper throughhole 27 , and can also communicate with the detection chamber 32 through the lower throughhole 28 . The upper throughhole 27 and the lower throughhole 28 cannot communicate with the empty groove at the same time. The shape of the empty slot can be circular, square, or other regular or irregular shapes. The piston 23 can change the position of the piston 23 in thepiston hole 22 via the operator's fingers or other implements, such as pushing parts, so as to achieve the purpose of transferring the liquid. In thetransfer chamber 22, several annular grooves may be formed by the piston 23, thepiston hole 22 and therubber ring 24, such as an openannular groove 26 and a closedannular groove 7 for liquid transfer. Take the openannular groove 26 as an example. In the initial state, the openannular groove 26 communicates with thecollection chamber 21 by means of the upper throughhole 27. When there is a liquid sample in thecollection chamber 21, the liquid can enter the openannular groove 27 through the upper throughhole 27.Slot 26. Push the piston 23 so that the openannular groove 26 and the upper throughhole 27 are in a disconnected state, and when communicating with the lower throughhole 28, the liquid sample in the openannular groove 26 can flow into the detection chamber 32 through the lower throughhole 28, thereby starting the detection The reaction detects the presence of the analyte in the liquid sample. The present invention can also quantify the transferred liquid through the size of the openannular groove 26 .

本发明还涉及检测装置100的使用方法：收集液体样本；观察指示元件8并判断检测是否被激活；检测。优选的，检测装置100还包括将液体样本转移到检测腔32的转移腔22，指示元件8位于转移腔22并随着转移腔22的位置改变而改变位置。其使用方法包括：收集液体样本；推动转移腔22使液体样本从转移腔22流到检测腔32，其中指示元件8随着转移腔22的移动而移动；观察指示元件8并判断检测是否被激活；检测。其中优选的，检测装置100还包括一个观测检测是否被激活的观察窗口54。更为优选的，检测装置100的使用方法包括：收集液体样本；推动转移腔22使液体样本从转移腔22流到检测腔32，其中指示元件8随着转移腔22的移动而移动；从观察窗口54观察指示元件8的位置并判断激活检测；检测。The present invention also relates to a method of using the detection device 100: collecting a liquid sample; observing the indicatingelement 8 and judging whether the detection is activated; detection. Preferably, the detection device 100 further includes atransfer chamber 22 for transferring the liquid sample to the detection chamber 32 , and the indicatingelement 8 is located in thetransfer chamber 22 and changes position as the position of thetransfer chamber 22 changes. Its use method includes: collecting liquid samples; pushing thetransfer chamber 22 to make the liquid sample flow from thetransfer chamber 22 to the detection chamber 32, wherein theindicator element 8 moves with the movement of thetransfer chamber 22; observing theindicator element 8 and judging whether the detection is activated ; detection. Preferably, the detection device 100 further includes an observation window 54 for observing whether the detection is activated. More preferably, the method of using the detection device 100 includes: collecting a liquid sample; pushing thetransfer chamber 22 to make the liquid sample flow from thetransfer chamber 22 to the detection chamber 32, wherein the indicatingelement 8 moves with the movement of thetransfer chamber 22; The window 54 observes the position of the indicatingelement 8 and judges the activation detection; detection.

下面结合具体附图对本发明的实施例子来进行详细的说明。这些具体的实施例子仅仅是在不违背本发明精神下的有限列举，并不排除本领域的一般技术人员把现有技术和本发明结合而产生的其他具体的实施方案。The implementation examples of the present invention will be described in detail below in conjunction with specific drawings. These specific implementation examples are only limited enumerations without departing from the spirit of the present invention, and do not exclude other specific implementations produced by those skilled in the art by combining the prior art with the present invention.

实施例1Example 1

如图1，图2和图3所示，这种检测装置100，包括收集腔21和检测腔32，及其能将收集腔21中液体转移到检测腔32的活塞孔(转移腔)22。收集腔21包括杯身2，杯身2顶部设有杯口20，内部具有杯腔；杯口20设有杯盖1，该杯盖1、杯口20的横截面均为圆形，杯盖1与杯口20螺纹201连接。检测腔32底部设有杯座3，杯座3上开有插槽34，插槽34内有两个支撑条33，用于支撑插板上的突起56，使带有带测试条的测试卡5略微悬空于杯座的插槽34，这样的好处在于，在检测条吸收液体样本的过程中，检测试剂条52可以一直保持直立状态，不会因为弯曲而导致影响检测结果的目的。活塞孔22通过其上壁的上通孔27与杯身相通，并且通过下壁的下通孔28与插槽34相通，杯座3正对下通孔28处有一条与插槽34相通的横槽，下通孔28通过该横槽与插槽34相通。活塞孔22内置活塞23，该活塞23与活塞孔处于滑动密封配合，且该活塞23前端具有开放环形槽26。活塞23在第一位置处，开放环形槽26藉由上通孔27与杯腔相通，但与测试板5隔离，成为可容纳杯腔中留下的液体样本的空腔，活塞23上套有橡皮圈24。在第二位置处，开放环形槽26与杯腔隔离但藉由下通孔28与插槽34相通，上通孔27和下通孔28不能同时与开放环形槽26相通。上通孔27位于活塞孔的最高位置7，开口一端位于活塞孔22和杯身2内壁的交界处，另一端落在转移腔22突起于杯身2内壁的位置上。下通孔28位于活塞孔22的最低位置8，开口一端位于活塞孔22和杯身2内壁的交界处，另一端落在活塞孔22突起与检测腔32内壁的位置上。上通孔27和下通孔28呈带状的圆弧形，开口两端与通过活塞孔22的纵轴形成的夹角均为100度。上通孔27和下通孔28不处于同一平面。在活塞23的一端，设置有一个推动部件6，包括推柄60和阻拦环61，63，其中阻拦环有两个，在两个阻拦环中间有一个拿捏处62。阻拦环61，63之间以及阻拦环63和推柄60之间的连接比较容易被剥落，剥落的方式是通过拿捏处62，将阻拦环63从推柄60上撕开。另外，在活塞23和活塞孔22以及橡皮圈24组成的封闭环形槽7上，包裹了一层绿色的不干胶8。另外在插板53上开有一小孔54，相应的，尿杯100最外面的不干胶膜51上也留有一个与之对应的窗口55。在检测没有发生之前，窗口55和小孔54中是看不到绿色的不干胶7的，在检测被激活之后，活塞23被推柄60推到了相应位置，液体样本也发生了转移，同样，绿色的不干胶8也随着活塞23的移动而发生了移动，因而在上述的小孔54和窗口55正视可见绿色的不干胶8，表示液体样本已经从转移腔22进入检测腔32，检测已经被激活。As shown in FIG. 1 , FIG. 2 and FIG. 3 , this detection device 100 includes acollection chamber 21 and a detection chamber 32 , and a piston hole (transfer chamber) 22 capable of transferring the liquid in thecollection chamber 21 to the detection chamber 32 . Thecollection chamber 21 comprises acup body 2, the top of thecup body 2 is provided with acup mouth 20, and the inside has a cup chamber; thecup mouth 20 is provided with acup cover 1, and the cross sections of thecup cover 1 and thecup mouth 20 are circular, and thecup lid 1 is connected with thecup mouth 20 threaded 201. Acup holder 3 is provided at the bottom of the detection chamber 32, and aslot 34 is provided on thecup holder 3. Two support bars 33 are arranged in theslot 34 for supporting theprotrusion 56 on the plugboard, so that a test card with a test strip 5 is slightly suspended from theslot 34 of the cup holder. The advantage of this is that thedetection reagent strip 52 can always remain upright when the test strip absorbs the liquid sample, and will not affect the detection result due to bending. Thepiston hole 22 communicates with the cup body through the upper throughhole 27 of its upper wall, and communicates with theslot 34 through the lower throughhole 28 of the lower wall. A horizontal slot through which the lower throughhole 28 communicates with theslot 34 . Thepiston hole 22 has a built-in piston 23, and the piston 23 is in a sliding and sealing fit with the piston hole, and the front end of the piston 23 has an openannular groove 26. The piston 23 is at the first position, and the openannular groove 26 communicates with the cup chamber through the upper throughhole 27, but is isolated from the test plate 5, and becomes a cavity that can accommodate the liquid sample left in the cup chamber, and the piston 23 is covered with rubber ring24. In the second position, the openannular groove 26 is isolated from the cup cavity but communicates with theslot 34 through the lower throughhole 28 , and the upper throughhole 27 and the lower throughhole 28 cannot communicate with the openannular groove 26 at the same time. The upper throughhole 27 is located at thehighest position 7 of the piston hole, one end of the opening is located at the junction of thepiston hole 22 and the inner wall of thecup body 2 , and the other end falls on the position where thetransfer cavity 22 protrudes from the inner wall of thecup body 2 . The lower throughhole 28 is located at thelowest position 8 of thepiston hole 22 , one end of the opening is located at the junction of thepiston hole 22 and the inner wall of thecup body 2 , and the other end falls on the position where thepiston hole 22 protrudes and the inner wall of the detection chamber 32 . The upper throughhole 27 and the lower throughhole 28 are in the shape of a strip-shaped arc, and the angles formed between the two ends of the opening and the longitudinal axis passing through thepiston hole 22 are both 100 degrees. The upper throughhole 27 and the lower throughhole 28 are not in the same plane. At one end of the piston 23, apusher 6 is provided, including apush handle 60 and blocking rings 61, 63, wherein there are two blocking rings, and there is apinch 62 between the two blocking rings. The connection between the blocking rings 61 and 63 and between the blockingring 63 and the push handle 60 is relatively easy to be peeled off, and the way of peeling off is to tear the blockingring 63 from the push handle 60 by holding thepinch 62 . In addition, on the closedannular groove 7 formed by the piston 23 , thepiston hole 22 and therubber ring 24 , a layer of green self-adhesive 8 is wrapped. In addition, a small hole 54 is opened on the insertingplate 53 , and correspondingly, a correspondingwindow 55 is left on the outermost self-adhesive film 51 of the urine cup 100 . Before the detection did not take place, thegreen sticker 7 could not be seen in thewindow 55 and the small hole 54. After the detection was activated, the piston 23 was pushed to the corresponding position by the push handle 60, and the liquid sample was also transferred. , the green self-adhesive 8 also moves along with the movement of the piston 23, so the green self-adhesive 8 can be seen in the front view of the above-mentioned small hole 54 andwindow 55, indicating that the liquid sample has entered the detection chamber 32 from thetransfer chamber 22 , detection has been activated.

如图4和图5所示，活塞23在第一位置时，开放环形槽26对准上通孔27。使用时，将杯盖1取下，将液体样本例如尿样加入杯腔，液体样本从上通孔27流到开放环形槽26形成的空腔。再利用拿捏处62将阻拦环61，63从活塞23上撕开，然后推动推柄60把活塞23推入活塞孔22深处，使开放环形槽26对准下通孔28。此时，液体样本从下通孔28流入杯座3的横槽上，在从横槽流入插槽34，与插在插槽34上的测试条52接触，激活检测。当开放环形槽26对准下通孔28时，封闭环形槽7相应对准了插板53上的小孔54，在尿杯的面板的窗口55和测试板的小孔54中，可以很明显得看到绿色的不干胶信号，显示检测已经激活，将检测结果显示出来。需要进一步检测时，可将杯腔中的液体样本送到实验室由专业人员进一步检测，确认检测结果。As shown in FIGS. 4 and 5 , when the piston 23 is in the first position, the openannular groove 26 is aligned with the upper throughhole 27 . When in use, thecup cover 1 is removed, and a liquid sample such as a urine sample is added to the cup cavity, and the liquid sample flows from the upper throughhole 27 to the cavity formed by the openannular groove 26 . Then use thehandle 62 to tear the blocking rings 61, 63 from the piston 23, and then push the push handle 60 to push the piston 23 into the depth of thepiston hole 22, so that the openannular groove 26 is aligned with the lower throughhole 28. At this time, the liquid sample flows into the horizontal groove of thecup holder 3 from the lower throughhole 28, flows into theslot 34 from the horizontal groove, and contacts thetest strip 52 inserted in theslot 34 to activate detection. When the openannular groove 26 was aligned with the lower throughhole 28, the closedannular groove 7 was aligned with the small hole 54 on the insertingplate 53, and in thewindow 55 of the panel of the urine cup and the small hole 54 of the test plate, it can be clearly You must see a green sticker signal, indicating that the detection has been activated, and the detection result will be displayed. When further testing is required, the liquid sample in the cup cavity can be sent to the laboratory for further testing by professionals to confirm the test results.

Claims (21)

1. a pick-up unit comprises and holds the test chamber that whether contains the detecting element of analyte in the analyzing samples, it is characterized in that, described pick-up unit also comprises an indicator elment that shows whether detection is activated.

2. pick-up unit as claimed in claim 1 is characterized in that described pick-up unit also comprises the transfer chamber of liquid sample being transferred to test chamber, and described indicator elment is positioned at transfer chamber and changes the position along with the position change of transfer chamber.

3. pick-up unit as claimed in claim 2 is characterized in that described transfer chamber comprises the piston hole that has piston, and described piston and piston hole are formed open ring groove that shifts for liquid and the closed ring groove of settling indicator elment.

4. pick-up unit as claimed in claim 1 is characterized in that, described pick-up unit comprises that also an observation detects the watch window that whether is activated.

5. pick-up unit as claimed in claim 4 is characterized in that described indicator elment can not be observed at watch window before detection is activated, can be observed at watch window after detection is activated.

6. as the described pick-up unit of one of claim 1 to 5, it is characterized in that described indicator elment comprises colored adhesive sticker.

7. as the described pick-up unit of one of claim 1 to 5, it is characterized in that described test chamber comprises test board, described test board comprises a through hole, can see indicator elment by this through hole after detection is activated.

8. pick-up unit as claimed in claim 2 is characterized in that, described pick-up unit also comprises a push mechanism that makes liquid sample flow to test chamber from transfer chamber; Whether described indicator elment moves by the position of indication transfer chamber indicates detection to be activated.

9. pick-up unit as claimed in claim 8 is characterized in that described push mechanism also comprises the barrier element that is connected as a single entity with push mechanism.

10. pick-up unit as claimed in claim 8, it is characterized in that, described transfer chamber is to comprise the piston hole that has piston, described barrier element covers the outside of piston, described push mechanism is positioned at an end of piston hole, when detection was not activated, barrier element and push mechanism were connected as a single entity; When detection was activated, barrier element separated with push mechanism.

11. pick-up unit as claimed in claim 10 is characterized in that, push mechanism is irreversible activation for the liquid flow activation of pick-up unit.

12. pick-up unit as claimed in claim 1 is characterized in that, the support component that described test chamber is also erected detecting element.

13. a method of using pick-up unit, pick-up unit comprise test chamber and indicator elment that shows whether detection is activated that holds the detecting element that whether contains analyte in the analyzing samples, it is characterized in that,

Collect liquid sample;

Observe indicator elment and judge to detect and whether be activated;

Detect.

14. method as claimed in claim 13 is characterized in that, it is characterized in that, described pick-up unit also comprises the transfer chamber of liquid sample being transferred to test chamber, and described indicator elment is positioned at transfer chamber and changes the position along with the position change of transfer chamber.

15. method as claimed in claim 14 is characterized in that,

Collect liquid sample;

Promote transfer chamber and make liquid sample flow to test chamber from transfer chamber, wherein indicator elment moves along with moving of transfer chamber;

Observe indicator elment and judge to detect and whether be activated;

Detect.

16. method as claimed in claim 14 is characterized in that, described transfer chamber comprises the piston hole that has piston, and described piston and piston hole are formed open ring groove that shifts for liquid and the closed ring groove of settling indicator elment.

17. method as claimed in claim 13 is characterized in that, described pick-up unit comprises that also an observation detects the watch window that whether is activated.

18. method as claimed in claim 17 is characterized in that,

Collect liquid sample;

Promote transfer chamber and make liquid sample flow to test chamber from transfer chamber, wherein indicator elment moves along with moving of transfer chamber;

Observe the position of indicator elment and judge whether detection is activated from watch window; Detect.

19. method as claimed in claim 17 is characterized in that, described indicator elment can not be observed at watch window before detection is activated, and can be observed at watch window after detection is activated.

20., it is characterized in that described indicator elment comprises colored adhesive sticker as the described method of one of claim 13 to 19.

21., it is characterized in that described test chamber comprises test board as the described method of one of claim 13 to 19, described test board comprises a through hole, can see indicator elment by this through hole after detecting activation.

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