1. the purification process of an allergen vaccine, the allergen extracting solution is prepared into allergen vaccine after ultrafiltration purification, ultrafiltration decolouring, acid treatment, dialysis purification process.

2. purification process according to claim 1, wherein: ultrafiltration purification adopts 100KD～300KD membrane ultrafiltration; 1KD～5KD membrane ultrafiltration decolouring is adopted in the ultrafiltration decolouring; Acid treatment is a ultrafiltration decolouring back extracting solution, dropwise adds 6～8M HCl, and the pH value of regulating stock solution is 1.5～2.5; Dialysis is that the extracting solution after the acid treatment is dialysed with 1KD～5KD bag filter.

3. purification process according to claim 2, wherein: ultrafiltration purification adopts the 100KD membrane ultrafiltration; The decolouring of 3KD membrane ultrafiltration is adopted in the ultrafiltration decolouring; The pH value that stock solution is regulated in acid treatment is 2; Dialysis is that the extracting solution after the acid treatment is dialysed with the 3KD bag filter.

4. according to the arbitrary described purification process of claim 1-3, wherein the allergen extracting solution prepares as follows:

1) defat: in the allergen raw material, added acetone or ether in 1: 2～1: 10 with volume ratio, room temperature defat under magnetic agitation, repeatable operation is colourless up to supernatant, in the ventilation drying;

2) extract: the raw material after the defat with 1: 10～1: 50 (w/v) ratio with buffer, buffer can be phosphate buffer, sodium bicarbonate buffer liquid and ammonium bicarbonate buffers, concentration is 50～200mM, PH is 6～8.5, stir or mechanical agitation extraction 2～24h preferred 1: 25 of ingredient proportion at 2～8 ℃ of condition lower magnetic forces;

3) centrifugal: extract mixture at 4000～6000rpm, centrifugal 15min under 4 ℃ of conditions gets supernatant then at 6000～8000rpm, and centrifugal 30min under 4 ℃ of conditions collects supernatant, discards precipitation or precipitates and extract with same condition again;

4) clarification filtration: supernatant is by filter paper, and cardboard or other aperture 10-0.22um film adopt a step or a plurality of step to filter clarification.

5. the preparation method of an allergen vaccine, the allergen that is selected from tree pollen, showy flowers of herbaceous plants powder, fungus, animal cuticle and hair, insecticide makes allergen vaccine through defat, extraction, centrifugal, clarification filtration, ultrafiltration purification, ultrafiltration decolouring, acid treatment, dialysis, aseptic filtration, dilution packing, lyophilizing.

6. according to the preparation method of claim 5, wherein:

Defat: be selected from the allergen raw material of tree pollen, showy flowers of herbaceous plants powder, fungus, animal cuticle and hair, insecticide and added acetone or ether in 1: 2～1: 10 with volume ratio, room temperature defat under magnetic agitation, repeatable operation is colourless up to supernatant, in the ventilation drying;

Extract: the raw material after the defat with 1: 10～1: 50 (w/v) ratio with buffer, buffer can be phosphate buffer, sodium bicarbonate buffer liquid and ammonium bicarbonate buffers, concentration is 50～200mM, PH is 6～8.5, stir or mechanical agitation extraction 2～24h ingredient proportion 1: 25 at 2～8 ℃ of condition lower magnetic forces;

Centrifugal: extract mixture at 4000～6000rpm, centrifugal 15min under 4 ℃ of conditions gets supernatant then at 6000～8000rpm, and centrifugal 30min under 4 ℃ of conditions collects supernatant, discards precipitation or precipitates and extract with same condition again;

Clarification filtration: supernatant is by filter paper, and cardboard or other aperture 10-0.22um film adopt a step or a plurality of step to filter clarification;

Ultrafiltration purification: the filtrate after the clarification is again through 100KD～300KD membrane ultrafiltration, and preferred 100KD film is collected filter liquor, removes macromolecule impurity;

The ultrafiltration decolouring: the extracting solution after macromole impurity is removed in ultrafiltration is through 1KD～5KD membrane ultrafiltration decolouring, in the process of ultrafiltration, constantly add buffer, when filter liquor when being colourless, with conductivity meter test filter liquor electrical conductivity and buffering liquid phase while, be the ultrafiltration terminal point, the pigment molecular that exists in free mode in the extracting solution in allergen is constantly being removed in the ultra-filtration process, when filter liquor is colourless when consistent with buffer with electrical conductivity, illustrates that the pigment that dissociates in the allergen extracting solution removes substantially; Acid treatment: extracting solution behind 1KD～5KD membrane ultrafiltration, dropwise add 6～8M HCl, the pH value of regulating stock solution is 2～3, and the pigment that is attached on the protein is dissociated;

Dialysis: acid treatment extracting solution is later being stirred 10-30min at ambient temperature on magnetic stirring apparatus, 24-36h dialyses under 4 ℃ of conditions in the water for injection that 50-100 times of volume PH is 6-8.5, in dialysis procedure, container is put on the magnetic stirring apparatus, allows the bag filter freedom slowly rotate;

Regulate PH: dropwise drip 1M NaOH in the extracting solution after the purification dialysis and regulate PH to 6.5～7.5;

Add 1%～3% mannitol and 0.1%～1% human albumin in the extracting solution after regulating pH value;

Lyophilization obtains the allergen vaccine lyophilized powder.

7. according to the preparation method of claim 6, wherein: clarification filtration uses cardboard filter; Ultrafiltration purification adopts the 100KD film; The 3KD film is adopted in the ultrafiltration decolouring; The pH value of regulating stock solution in the acid treatment step is 2; Stirred 30 minutes in the dialysis step, dialysed 24 hours.

8. an allergen preparation is characterized in that the preparation method preparation according to claim 6 or 7.

9. the original preparation of allergic effect according to claim 8, dissolve preparation lyophilizing dry powder in proportion with buffer according to claim 6 or 7, add 0.4% phenol and 0.5%NaCl and be mixed with desensitization stock solution, the allergen vaccine stock solution of preparation can be as subcutaneous injection desensitization, Sublingual immunity desensitization and subcutaneous injection pricking method diagnosis.

10. the original preparation of allergic effect according to claim 9 is characterized in that: add 50% glycerol and be mixed with pricking method liquid, or add Al (OH) 3, tyrosine, MPL adjuvant and be mixed with and contain adjuvant allergen vaccinate.