CN101569766B - Membrane oxygenator - Google Patents

Abstract

The invention relates to the technical field of medical appliance products, in particular to a membrane oxygenator which comprises a blood storage room, a temperature change room and an oxygenating room, wherein an upper connecting rack is arranged below the blood storage room; the temperature change room and the oxygenating room are fixedly connected through a lower connecting rack; the upper connecting rack and the lower connecting rack are buckled and matched with each other; and the temperature change room and the oxygenating room are communicated through a pipeline connecting device. The integral structure of the membrane oxygenator can be disassembled and can be assembled conveniently and stably. In addition, a venous blood drainage nozzle and an absorption nozzle on the blood storage room can be independently rotated at 360 degrees so as to be convenient for connecting a flexible pipe and can reduce the precharge quantity of blood. The structure of the oxygenating room can prevent the phenomenon of blood bubbles, and the pipeline connecting device adopted by the temperature change room and the oxygenating room can shorten the length of a connecting pipeline so as to ensure that a cavity space of the connecting pipeline is reduced, thus, the precharge quantity of the blood can be reduced.

Description

A kind of membrane oxygenator

Technical field:

The present invention relates to the medical device product technical field, refer in particular to a kind of membrane oxygenator.

Background technology:

ECMO is mainly used in in the operation on heart enforcement as a kind of medical skill.This technology can short-term substitute cardiopulmonary fully, to implement open heart operations.Its principle is with outside the intravital venous blood lead body, through injecting patient artery or Venous system behind the special substance artificial heart-lung bypass oxygenate, plays part cardiopulmonary vicarious function, keeps human internal organ tissue oxygenation blood and supplies.

Usually to use oxygenator in this technology.Its function is that non-oxygenated blood oxygenate is become oxygenated blood, is artificial lung again.Oxygenator generally includes two kinds of membrane oxygenator and doughnut oxygenators.Wherein, because the membrane oxygenator compatibility is good, rare blood plasma seepage, blood constituent destroys little, is fit to long-time plurality of advantages such as auxiliary and is extensively adopted.

Usually membrane oxygenator comprises: have the blood storage chamber of memory function, the temperature-changing chamber with adjusting blood heat and oxygenation chamber and constitute.

Blood storage chamber is a cavity that is used for storing blood, and it is provided with a little drain mouths of vein, some attraction mouths, blood outlet.Venous blood flows in the blood storage chamber through the drain mouth is set, and flows out through blood outlet.And attract mouth to can be used for the circulation of oxygenator inner blood, gas.

Temperature-changing chamber is used for the temperature of blood is regulated, and for example when operation, can temperature be reduced, and after operation is accomplished, blood heat is heightened again.What it adopted is water-cooling pattern, and through circulation water the blood heat of flowing through is regulated.

The function of oxygenation chamber just is that non-oxygenated blood oxygenate becomes oxygenated blood.

There is certain defective in the present membrane oxygenator:

One, for the blood storage chamber dioxy; In traditional membrane oxygenator: drain mouth in the blood storage chamber, to attract mouth be fixed structure, and it exists the interface direction not corresponding when hose connection sometimes; Just needing this moment changes around flexible pipe, makes hose connection to drain mouth or specified attraction mouth.So just produce a problem, change when flexible pipe, the flexible pipe of coiling not only forms yoke easily, and has increased the use length of flexible pipe, makes the preparatory momentum of oxygenator blood increase virtually.In addition, flexible pipe is reeled to insert corresponding interface, inconvenient in the operation.

Two, in the traditional membrane oxygenator: oxygenation chamber and temperature-changing chamber are to adopt integrative-structure, perhaps adopt molding respectively, are connected to form then.For adopting the oxygenation chamber and the temperature-changing chamber of molding mode respectively, during use, must the two be coupled together through pipeline, and there is following shortcoming in the pipeline connected mode that adopts at present:

1, the cavity space of connection pipeline is bigger, and it is more to cause being placed in the interior blood of this connection pipeline, thereby causes the priming volume of blood to increase.

2, the pipe connecting structure that adopts at present, its connection procedure is comparatively loaded down with trivial details, and is not easy to operate.

Three, present membrane oxygenator is in the oxygenate exchange process, if the fibrous membrane pipe breaks in the oxygenation chamber, then the gas in the fibrous membrane pipe will be revealed, and sneak in the blood in the fibrous membrane ligament.So just cause and form bleeding blister in the blood.For preventing that the patient from importing the blood that has gas, follow-up must the processing bleeding blister so just increases operation sequence.

Summary of the invention:

Technical problem to be solved by this invention is to overcome the existing deficiency of present product exactly, provide a kind of simple in structure, stable, and the preparatory momentum of blood is little, in the easy to use and reliable membrane oxygenator.

For solving the problems of the technologies described above; The present invention has adopted following technical scheme: the present invention includes: blood storage chamber, temperature-changing chamber and oxygenation chamber; The blood storage chamber below is provided with link on, and temperature-changing chamber is fixedly connected through following link with oxygenation chamber, and last link is clasped with following link; Be communicated with through assembling pipe joint between temperature-changing chamber and the oxygenation chamber.

Described assembling pipe joint comprises: be separately positioned on interior pipe, outer tube on temperature-changing chamber and the oxygenation chamber, manage in wherein outer tube sleeve is located at, and through a thread bush interior pipe is connected with outer tube.

Pipe is arranged on the oxygenation chamber in described, and described outer tube is arranged on the temperature-changing chamber, and perhaps described interior pipe is arranged on the temperature-changing chamber, and described outer tube is arranged on the oxygenation chamber, and pipe is the conical pipe that cooperatively interacts with the outer tube socket part in described.

Described thread bush is sheathed on the interior pipe, and through the flange of molding on the interior pipe thread bush is defined on the interior pipe, and outer tube inserts between interior pipe and the thread bush, and the outer tube outer rim forms the external screw thread that is threaded with thread bush formation.

The blood storage chamber main body is a chamber that is used for storage of blood, and chamber is provided with venous blood drain mouth and the some attraction mouths that is communicated with the chamber inner chamber, described venous blood drain mouth, attracts mouth to be rotatably connected on chamber.

Rotatable on the described chamber upper end cover rotating disk is installed, described attraction mouth is arranged at rotating disk circumference side, and described cover venous blood drain mouth is arranged at center, rotating disk upper surface, and adopts rotating pin-jointed structure between itself and the rotating disk.

Described temperature-changing chamber has a blood inlet, a blood outlet, and blood is entered in the temperature-changing chamber by blood inlet, is flowed out by blood outlet; Also be provided with water circle device in the temperature-changing chamber, water inlet and outlet are arranged at the temperature-changing chamber bottom, and alternating temperature water is flowed out by outlet by in the water inlet entering temperature-changing chamber blood being cooled off or heating then.

The hollow fiber film tube that described oxygenation chamber comprises chamber and is positioned at chamber, this chamber top are provided with into the oxygen mouth, go into blood mouth, circulating exhaust mouth, and this chamber bottom is provided with outlet nozzle, blood outlet; Chamber comprises: superposed inlet plenum, the switch room that is positioned at the middle part and the discharge chamber that is positioned at the bottom; The fibrous membrane pipe is positioned at the switch room, and its two ends are formed with encapsulation part, so that gas passage and blood channel are isolated.

Described chamber is advanced the oxygen mouth and is arranged on the inlet plenum; Outlet nozzle is arranged on the discharge chamber; Going into blood mouth, circulating exhaust mouth and blood outlet is arranged in the switch room; Wherein, advancing the oxygen mouth is communicated with outlet nozzle through hollow fiber film tube; Going into blood mouth, circulating exhaust mouth and blood outlet is communicated with through the gap between hollow fiber film tube; Pass the fibrous membrane pipe by advancing the oxygen that the oxygen mouth gets into, pass oxygen oxygenate in gap and the fibrous membrane pipe between the fibrous membrane pipe by going into blood that the blood mouth gets into, and by the blood outlet outflow, the carbon dioxide of discharging behind the oxygenate is discharged by outlet nozzle.

In sum, the present invention has following advantage:

1, overall structure is detachable structure, and is easy to assembly, and structure is firm.

2, blood storage chamber upper vein blood drain mouth, attract mouth all can realize independent 360 degree rotations, be convenient to hose connectionly, and can reduce the blood priming amount.

3, the structure of oxygenation chamber can prevent the generation of bleeding blister phenomenon.

4, temperature-changing chamber can shorten the length that is connected pipeline with the assembling pipe joint that oxygenation chamber adopts, and reduces thereby order connects the cavity space of pipeline, so just can reduce the priming volume of blood.

Description of drawings:

Below in conjunction with accompanying drawing the present invention is further described:

Fig. 1 is a three-dimensional structure diagram of the present invention;

Fig. 2 is the vertical view of blood storage chamber of the present invention;

Fig. 3 is the axonometric chart of oxygenation chamber of the present invention;

Fig. 4 is the internal structure cutaway view of oxygenation chamber of the present invention;

Fig. 5 is a sketch map under the connecting device not-connected status of the present invention;

Fig. 6 is the sketch map under the connecting device connection status of the present invention.

The specific embodiment:

See Fig. 1, this is the structural representation of membrane oxygenator of the present invention, the present invention includes: haveblood storage chamber 1, theoxygenation chamber 3 of memory function and have temperature-changingchamber 2 formations of regulating blood heat.Wherein, be communicated with through assembling pipe joint 4 between temperature-changingchamber 2 and theoxygenation chamber 3.

Referring to Fig. 1,2,blood storage chamber 1 main body is achamber 10 that is used for storage of blood, andchamber 10 is provided with the venousblood drain mouth 11 and someattraction mouths 12 that is communicated withchamber 1 inner chamber.Wherein, onchamber 10 upper end covers, turn a rotatingdisk 14 is installed, describedattraction mouth 12 is arranged at rotatingdisk 14 circumference sides.Venousblood drain mouth 11 is arranged at center, rotatingdisk 14 upper surface, and adopts rotating pin-jointed structure between itself and the rotating disk 14.Be provided with somedosing mouths 13 in rotatingdisk 14 upper surfaces.

Among the present invention, rotatingdisk 14 can adopt axis hole cutting ferrule mode to be installed on the upper end cover of chamber 10.In like manner, venousblood drain mouth 11 also can adopt axis hole cutting ferrule mode to be installed on the rotating disk 14.Like this,drain mouth 11, rotatingdisk 14 can be distinguished independent rotation, and can not produce mutual interference.

During use, can these interfaces be rotated to a suitable angle and hose connection.So, not only easy to use, flexible, be convenient to hose connectionly, and owing to be used to connect the interface of flexible pipe and can independently rotate by any direction, so can reduce flexible pipe use length, the blood priming amount is less.

Be provided withlink 16 on ablood outlet 15 and below the blood storage chamber 1.Blood outlet 15 is communicated withchamber 10, and the blood ofchamber 10 storages is flowed out by blood outlet 15.Last link 16 is provided with andchamber 10 belows, and its housing withchamber 10 is solidified as a whole, andlink 16 is used to connect temperature-changingchamber 2 andoxygenation chamber 3 on this.

Be communicated with through assembling pipe joint 4 between temperature-changingchamber 2 and theoxygenation chamber 3, and temperature-changingchamber 2 andoxygenation chamber 3 are fixed together throughlink 5 down.Thistime link 5 is positioned at temperature-changingchamber 2 andoxygenation chamber 3 tops, and assembling pipe joint 4 is communicated with temperature-changingchamber 2 with oxygenation chamber 3.To connect steadiness between the two in order strengthening, between temperature-changingchamber 2 andoxygenation chamber 3, also to be connected with connection strap 6, this connection strap 6 is adhesively fixed temperature-changingchamber 2 andoxygenation chamber 3.

Last link 16 can form with followinglink 5 and be clasped, and through the cooperation oflink 16,5 up and down, withblood storage chamber 1, temperature-changingchamber 2,oxygenation chamber 3, is connected to form an integral body.

Temperature-changingchamber 2 has ablood inlet 21, ablood outlet 22, and blood is entered in the temperature-changingchamber 2 byblood inlet 21, is flowed out by blood outlet 22.Also be provided with water circle device in the temperature-changingchamber 2,water inlet 23 is arranged at temperature-changingchamber 2 bottoms withoutlet 24, and alternating temperature water is flowed out byoutlet 24 by in thewater inlet 23 entering temperature-changingchambers 2 blood being cooled off or heating then.

See Fig. 3,4, the hollowfiber film tube 30 thatoxygenation chamber 3 comprises chamber and is positioned at chamber.This chamber top is provided with intooxygen mouth 36, goes intoblood mouth 34, circulating exhaust mouth 38.This chamber bottom is provided withoutlet nozzle 37, blood outlet 35.Chamber comprises: superposedinlet plenum 31, theswitch room 32 that is positioned at the middle part and thedischarge chamber 33 that is positioned at the bottom.Fibrous membrane pipe 30 is positioned atswitch room 32, and its two ends are formed withencapsulation part 301, so that gas passage and blood channel are isolated.

Advancingoxygen mouth 36 is arranged on theinlet plenum 31;Outlet nozzle 37 is arranged on the discharge chamber 33.Going intoblood mouth 34, circulatingexhaust mouth 38 andblood outlet 35 is arranged in the switch room 32.Wherein, advancingoxygen mouth 36 is communicated withoutlet nozzle 37 through hollow fiber film tube 30.Go into the gap connection ofblood mouth 34, circulatingexhaust mouth 38 andblood outlet 35 through 30 of hollow fiber film tubes.Passfibrous membrane pipe 30 by advancing the oxygen thatoxygen mouth 36 gets into, by going into oxygen oxygenate in gap that blood thatblood mouth 34 gets intopasses 30 of fibrous membrane pipes and the fibrous membrane pipe, and flowed out byblood outlet 35, the carbon dioxide of discharging behind the oxygenate is byoutlet nozzle 37 discharges.

See Fig. 4, whenoxygenation chamber 3 used, at first, oxygen got in theinlet plenum 31 by advancingoxygen mouth 36, and gets in the hollow fiber film tube 30.Simultaneously, venous blood enters intoswitch room 32 by going intoblood mouth 34, and blood passes the gap and the interior oxygen oxygenate of fibrous membrane pipe of 30 of fibrous membrane pipes.Blood behind the oxygenate will flow out through blood outlet 35.And the carbon dioxide of discharging behind the oxygenate will get intodischarge chamber 33, and discharged byoutlet nozzle 37.

Afterfibrous membrane pipe 30 breaks,fibrous membrane pipe 30 interior gases will be revealed and get in the blood, because gas is little than density of blood, it will float, and the blood after the oxygenate completion has by the blood outlet that is positioned at the below 35 outflows, has so just realized that gas, blood system leave.And the gas of come-up will be discharged through circulating exhaust mouth 39, has so just effectively avoided the generation of bleeding blister phenomenon.

See Fig. 5,6, assembling pipe joint 4 comprises: be separately positioned oninterior pipe 41,outer tube 42 on temperature-changingchamber 2 and theoxygenation chamber 3, and whereininterior pipe 41blood outlets 22 as temperature-changingchamber 2, andouter tube 42 is as theblood inlet 34 of oxygenation chamber 3.Manage on 41 inouter tube 42 is sheathed on, andinterior pipe 41 is connected withouter tube 42 through a thread bush 43.Wherein, On thepipe 41, its inside formed female thread 432, and is formed with a flange 431 at an end ofthread bush 43 inthread bush 43 was sheathed on; Oninterior pipe 41, also form a flange 411,thread bush 43 is defined on theinterior pipe 41 through this flange 411 and the staggered of flange 431 formation.Outer tube 42 inserts betweeninterior pipe 41 and thethread bush 43, andouter tube 42 outer rims form the external screw thread 421 that is threaded withthread bush 43 formation.

Combine closely withouter tube 42 socket part in order to ensureinterior pipe 41, the slit can not occur cooperating.Pipesocket part 412 is mutual corresponding conical pipe with outertube socket part 422 among the present invention.When interiorpipe socket part 412 is inserted in the outertube socket part 422, just can form and combine closely like this.And if adopt cylindrical tube to cooperatively interact, closely cooperate if will form, processing precision of products must reach higher level, and this has just improved production cost, and cooperates seal also to be difficult to ensure.Simultaneously, rotary threadedcover 43 makesthread bush 43 and external screw thread 421 on theouter tube 42 form and is threaded in outertube socket parts 422 are inserted in interiorpipe socket part 412, prevents interiorly to manage 41 and separate withouter tube 42.

Pipe 41 can be arranged on theoxygenation chamber 3 in of the present invention, andouter tube 42 can be arranged on the temperature-changingchamber 2, otherwiseinterior pipe 41 is arranged on the temperature-changingchamber 2, and it also is feasible on theoxygenation chamber 3 thatouter tube 42 is arranged on.In like manner,thread bush 43 is arranged on theouter tube 42, one section external screw thread that cooperates with thread bush of molding also is feasible oninterior pipe 41, and its structure and above-mentioned similar is not being given unnecessary details here one by one.

The present invention is owing to adopt technique scheme, and the connecting pipe betweeninterior pipe 41 and theouter tube 42 just forms and closely cooperates, and the slit can not occur.In addition, because theinterior pipe 41, theouter tube 42 that are separately positioned on temperature-changingchamber 2 and theoxygenation chamber 3 adopt the socket modes, so just shortened the length that connects pipeline, thereby order connects the cavity space minimizing of pipeline, so just can reduce the priming volume of blood.

Certainly, the above is an instance of the present invention only, is not to limit practical range of the present invention, and all equivalences of doing according to the described structure of claim of the present invention, characteristic and principle change or modify, and all should be included in the claim of the present invention.

Claims (8)

1. membrane oxygenator; It comprises: blood storage chamber (1), temperature-changing chamber (2) and oxygenation chamber (3); It is characterized in that: blood storage chamber (1) below is provided with link on (16); Temperature-changing chamber (2) is fixedly connected through following link (5) with oxygenation chamber (3), and last link (16) is clasped with following link (5); Be communicated with through assembling pipe joint (4) between temperature-changing chamber (2) and the oxygenation chamber (3); Said assembling pipe joint (4) comprising: be separately positioned on interior pipe (41), outer tube (42) on temperature-changing chamber (2) and the oxygenation chamber (3), its middle external tube (42) is sheathed on the interior pipe (41), and through a thread bush (43) interior pipe (41) is connected with outer tube (42).

2. a kind of membrane oxygenator according to claim 1; It is characterized in that: pipe (41) is arranged on the oxygenation chamber (3) in described; Described outer tube (42) is arranged on the temperature-changing chamber (2); Pipe (41) is arranged on the temperature-changing chamber (2) in perhaps described, and described outer tube (42) is arranged on the oxygenation chamber (3), and pipe (41) is the conical pipe that cooperatively interacts with outer tube (42) socket part in described.

3. a kind of membrane oxygenator according to claim 2; It is characterized in that: described thread bush (43) is sheathed on the interior pipe (41); And the flange (411) of going up molding through interior pipe (41) is defined in thread bush (43) on the interior pipe (41); Manage between (41) and the thread bush (43) in outer tube (42) inserts, and outer tube (42) outer rim forms the external screw thread (421) that is threaded with thread bush (43) formation.

4. according to any described a kind of membrane oxygenator among the claim 1-3; It is characterized in that: blood storage chamber (1) main body is a chamber (10) that is used for storage of blood; And chamber (10) is provided with venous blood drain mouth (11) and the some attraction mouths (12) that is communicated with chamber (10) inner chamber, and described venous blood drain mouth (11), attraction mouth (12) are rotatably connected on the chamber (10).

5. a kind of membrane oxygenator according to claim 4; It is characterized in that: be rotatablely equipped with a rotating disk (14) on described chamber (10) upper end cover; Described attraction mouth (12) is arranged at rotating disk (14) circumference side; Described venous blood drain mouth (11) is arranged at rotating disk (14) center, upper surface, and adopts rotating pin-jointed structure between itself and the rotating disk (14).

6. a kind of membrane oxygenator according to claim 5 is characterized in that: described temperature-changing chamber (2) has a blood inlet (21), a blood outlet (22), and blood is entered in the temperature-changing chamber (2) by blood inlet (21), is flowed out by blood outlet (22); Temperature-changing chamber also is provided with water circle device in (2), and water inlet (23) is arranged at temperature-changing chamber (2) bottom with outlet (24), and alternating temperature water is flowed out by outlet (24) by in water inlet (23) the entering temperature-changing chamber (2) blood being cooled off or heating then.

7. a kind of membrane oxygenator according to claim 4; It is characterized in that: the hollow fiber film tube (30) that described oxygenation chamber (3) comprises a chamber and is positioned at the chamber of this oxygenation chamber; The chamber top of this oxygenation chamber is provided with into oxygen mouth (36), goes into blood mouth (34), circulating exhaust mouth (38), and the chamber bottom of this oxygenation chamber is provided with outlet nozzle (37), blood outlet (35); The chamber of oxygenation chamber comprises: superposed inlet plenum (31), the switch room (32) that is positioned at the middle part and the discharge chamber (33) that is positioned at the bottom; Fibrous membrane pipe (30) is positioned at switch room (32), and its two ends are formed with encapsulation part (101), so that gas passage and blood channel are isolated.

8. a kind of membrane oxygenator according to claim 7 is characterized in that: describedly advance oxygen mouth (36) and be arranged on the inlet plenum (31); Outlet nozzle (37) is arranged on the discharge chamber (33); Going into blood mouth (34), circulating exhaust mouth (38) and blood outlet (35) is arranged in the switch room (32); Wherein, advancing oxygen mouth (36) is communicated with outlet nozzle (37) through hollow fiber film tube (30); Going into blood mouth (34), circulating exhaust mouth (38) and blood outlet (35) is communicated with through the gap between hollow fiber film tube (30); Oxygen by advancing oxygen mouth (36) entering passes fibrous membrane pipe (30); Pass gap and the interior oxygen oxygenate of fibrous membrane pipe between fibrous membrane pipe (30) by the blood of going into blood mouth (34) entering; And by blood outlet (35) outflow, the carbon dioxide of discharging behind the oxygenate is discharged by outlet nozzle (37).

Images