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Application filed by Genentech IncfiledCriticalGenentech Inc
Publication of CL2008000493A1publicationCriticalpatent/CL2008000493A1/en
C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
C12N9/14—Hydrolases (3)
C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Gyroscopes (AREA)
Compression, Expansion, Code Conversion, And Decoders (AREA)
Digital Transmission Methods That Use Modulated Carrier Waves (AREA)
CL200800493A2007-02-162008-02-15 POLYPEPTIDE THAT SPECIFICALLY JOINS A PDZ DOMAIN OF PROTEIN HTRA1; POLINUCLEOTIDE THAT CODIFIES IT; METHOD OF PRODUCTION; ANTIBODY THAT JOINS HIM; AND ITS USE TO TREAT PATHOLOGIES RELATED TO THE HTRA1 PROTEIN.CL2008000493A1 (en)
POLYPEPTIDE THAT SPECIFICALLY JOINS A PDZ DOMAIN OF PROTEIN HTRA1; POLINUCLEOTIDE THAT CODIFIES IT; METHOD OF PRODUCTION; ANTIBODY THAT JOINS HIM; AND ITS USE TO TREAT PATHOLOGIES RELATED TO THE HTRA1 PROTEIN.
POLYPEPTIDE THAT SPECIFICALLY JOINS A PDZ DOMAIN OF PROTEIN HTRA1; POLINUCLEOTIDE THAT CODIFIES IT; METHOD OF PRODUCTION; ANTIBODY THAT JOINS HIM; AND ITS USE TO TREAT PATHOLOGIES RELATED TO THE HTRA1 PROTEIN.
Antibody that specifically binds to the fibroblastic activation protein (fap); polynucleotide that encodes it; vector; host cell; Method of production; pharmaceutical formulation that includes it; and its use to treat cancer.
Use of a binding protein with a dual variable domain of immunoglobulin (dvd-ig) that binds to il-1 alpha and il-1 beta to prepare a useful medication for the treatment of osteoarthritis
ANTIGEN UNION PROTEIN THAT JOINS THE HUMAN GLUCAGON RECEIVER; NUCLEIC ACID THAT CODIFIES IT; METHOD OF PRODUCTION; PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT; AND ITS USE TO TREAT OR PREVENT TYPE 2 DIABETES.
Chimeric or humanized antibody or fragment thereof that specifically bind to at least one epitope in the beta-amyloid protein; nucleic acid molecule that encodes it; composition that includes it; and its use to treat diseases associated with the formation of amyloid plaques.
Isolated antibody or antigen binding fragment thereof that specifically binds to human cd48 and blocks the interaction between human cd48 and a cd48 receptor; pharmaceutical composition that includes it; And its use.
Isolated antibody or fragment that binds to an inactive state of a her receptor; pharmaceutical composition that includes it; use of the antibody to treat cancer.
Antigen-binding protein that binds human interleukin-23 (yl-23); pharmaceutical composition comprising it; and its use to treat immune mediated inflammations
Monoclonal antibody that binds to beta amyloid peptide n3pglu or antigen binding fragment thereof; pharmaceutical composition that includes it; and its use to treat Alzheimer's disease.
PROTEIN FUSION THAT CONSISTS IN AN FC REGION OF AN IMMUNOGLOBULIN WITH A FRAGMENT OR SOLUBLE DOMAIN OF A RECEIVER FOR FGF; POLINUCLEOTIDO THAT CODIFIES AND VECTOR AND CELL THAT UNDERSTAND IT; PHARMACEUTICAL COMPOSITION INCLUDING PROTEIN FU
Monoclonal antibodies which is anti-binding protein at 43 kda tar DNA (tdp-43); polynucleotide that encodes it; pharmaceutical composition that contains it; antibody use.
Monoclonal antibody that recognizes a conformational epitope and binds to polymeric soluble amyloid peptides and oligomeric amyloid peptides; polynucleotide that encodes it; composition that includes it; and its use to treat diseases associated with amyloid proteins.