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CA913077A - Process of preparing n-substituted 14-hydroxydihydronormorphines - Google Patents

Process of preparing n-substituted 14-hydroxydihydronormorphines

Info

Publication number
CA913077A
CA913077ACA913077ACA913077DACA913077ACA 913077 ACA913077 ACA 913077ACA 913077 ACA913077 ACA 913077ACA 913077D ACA913077D ACA 913077DACA 913077 ACA913077 ACA 913077A
Authority
CA
Canada
Prior art keywords
hydroxydihydronormorphines
substituted
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA913077A
Inventor
J. Pachter Irwin
Soloway Harold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENDO LABORATORIES
Original Assignee
ENDO LABORATORIES
Publication date
Application grantedgrantedCritical
Publication of CA913077ApublicationCriticalpatent/CA913077A/en
Expiredlegal-statusCriticalCurrent

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CA913077AProcess of preparing n-substituted 14-hydroxydihydronormorphinesExpiredCA913077A (en)

Applications Claiming Priority (1)

Application NumberPriority DateFiling DateTitle
CA913077T

Publications (1)

Publication NumberPublication Date
CA913077Atrue CA913077A (en)1972-10-24

Family

ID=36420635

Family Applications (1)

Application NumberTitlePriority DateFiling Date
CA913077AExpiredCA913077A (en)Process of preparing n-substituted 14-hydroxydihydronormorphines

Country Status (1)

CountryLink
CA (1)CA913077A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4161597A (en)*1976-12-201979-07-17Research CorporationN-alkyl-14-hydroxymorphinans and derivatives
US4232028A (en)*1979-06-181980-11-04Sisa, Incorporated17-Cyclobutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α-methylmorphinan-6-one, and method of treating pain with it
WO1981000409A1 (en)*1979-08-091981-02-19Mallinckrodt IncIntermediate compounds for preparation of morphine derivatives
US4322426A (en)*1980-04-281982-03-30E. I. Du Pont De Nemours And Company17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
US4451470A (en)*1982-07-061984-05-29E. I. Du Pont De Nemours And CompanyAnalgesic, antagonist, and/or anorectic 14-fluoromorphinans
US4667037A (en)*1985-06-061987-05-19E. I. Du Pont De Nemours And CompanyDealkylation of opioid ethers
US4795813A (en)*1981-08-171989-01-03The Florida Board Of Regents On Behalf Of The Florida State UniversitySynthesis of derivatives of codeine and other 3-O-alkylmorphines
WO1991005768A1 (en)*1989-10-161991-05-02The United States Of America, Represented By The Secretary, United States Department Of CommerceTotal synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates
US5668285A (en)*1986-10-311997-09-16The United States Of America As Represented By The Department Of Health And Human ServicesTotal synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
WO2012151669A1 (en)*2011-05-062012-11-15Brock UniversityProcess for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer

Cited By (15)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US4161597A (en)*1976-12-201979-07-17Research CorporationN-alkyl-14-hydroxymorphinans and derivatives
US4232028A (en)*1979-06-181980-11-04Sisa, Incorporated17-Cyclobutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α-methylmorphinan-6-one, and method of treating pain with it
WO1981000409A1 (en)*1979-08-091981-02-19Mallinckrodt IncIntermediate compounds for preparation of morphine derivatives
US4322426A (en)*1980-04-281982-03-30E. I. Du Pont De Nemours And Company17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
US4795813A (en)*1981-08-171989-01-03The Florida Board Of Regents On Behalf Of The Florida State UniversitySynthesis of derivatives of codeine and other 3-O-alkylmorphines
US4451470A (en)*1982-07-061984-05-29E. I. Du Pont De Nemours And CompanyAnalgesic, antagonist, and/or anorectic 14-fluoromorphinans
US4667037A (en)*1985-06-061987-05-19E. I. Du Pont De Nemours And CompanyDealkylation of opioid ethers
US5668285A (en)*1986-10-311997-09-16The United States Of America As Represented By The Department Of Health And Human ServicesTotal synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
WO1991005768A1 (en)*1989-10-161991-05-02The United States Of America, Represented By The Secretary, United States Department Of CommerceTotal synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates
WO2012151669A1 (en)*2011-05-062012-11-15Brock UniversityProcess for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer
CN103619847A (en)*2011-05-062014-03-05布鲁克大学Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer
JP2014514339A (en)*2011-05-062014-06-19ブロック ユニバーシティ Process for the preparation of morphine analogues by metal-catalyzed N-demethylation / functionalization and intramolecular group transfer
US8946214B2 (en)2011-05-062015-02-03Brock UniversityProcess for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer
US9108967B2 (en)2011-05-062015-08-18Brock UniversityProcess for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer
US9533993B2 (en)2011-05-062017-01-03Brock UniversityProcess for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer

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