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CA2474701A1 - Preparation of biodegradeable microparticles containing a biologically active agent - Google Patents

Preparation of biodegradeable microparticles containing a biologically active agentDownload PDF

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Publication number
CA2474701A1
CA2474701A1CA002474701ACA2474701ACA2474701A1CA 2474701 A1CA2474701 A1CA 2474701A1CA 002474701 ACA002474701 ACA 002474701ACA 2474701 ACA2474701 ACA 2474701ACA 2474701 A1CA2474701 A1CA 2474701A1
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Canada
Prior art keywords
active agent
biologically active
biodegradeable
preparation
microparticles containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
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CA002474701A
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French (fr)
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CA2474701C (en
Inventor
J. Michael Ramstack
Paul F. Herbert
Jan Strobel
Thomas J. Atkins
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Alkermes Inc
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Individual
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First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=27387578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2474701(A1)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by IndividualfiledCriticalIndividual
Publication of CA2474701A1publicationCriticalpatent/CA2474701A1/en
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Publication of CA2474701CpublicationCriticalpatent/CA2474701C/en
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Abstract

A process for preparing biodegradable microparticles comprising a biodegradable polymeric binder and a biologically active agent. A first phase, comprising the active agent and the polymer, and a second phase are pumped through a static mixer into a quench liquid to form microparticles containing the active agent. Preferably, a blend of at least two substantially non-toxic solvents, free of halogenated hydrocarbons, is used to dissolve or disperse the agent and dissolve the polymer.
CA002474701A1993-11-191994-11-18Preparation of biodegradeable microparticles containing a biologically active agentExpired - LifetimeCA2474701C (en)

Applications Claiming Priority (7)

Application NumberPriority DateFiling DateTitle
US15440993A1993-11-191993-11-19
US29878794A1994-08-311994-08-31
US33880594A1994-11-101994-11-10
US08/154,4091994-11-10
US08/298,7871994-11-10
US08/338,8051994-11-10
CA002176716ACA2176716C (en)1993-11-191994-11-18Preparation of biodegradable microparticles containing a biologically active agent

Related Parent Applications (1)

Application NumberTitlePriority DateFiling Date
CA002176716ADivisionCA2176716C (en)1993-11-191994-11-18Preparation of biodegradable microparticles containing a biologically active agent

Publications (2)

Publication NumberPublication Date
CA2474701A1true CA2474701A1 (en)1995-05-26
CA2474701C CA2474701C (en)2009-01-27

Family

ID=27387578

Family Applications (2)

Application NumberTitlePriority DateFiling Date
CA002176716AExpired - LifetimeCA2176716C (en)1993-11-191994-11-18Preparation of biodegradable microparticles containing a biologically active agent
CA002474701AExpired - LifetimeCA2474701C (en)1993-11-191994-11-18Preparation of biodegradeable microparticles containing a biologically active agent

Family Applications Before (1)

Application NumberTitlePriority DateFiling Date
CA002176716AExpired - LifetimeCA2176716C (en)1993-11-191994-11-18Preparation of biodegradable microparticles containing a biologically active agent

Country Status (11)

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US (1)US5654008A (en)
EP (5)EP0998917A1 (en)
JP (3)JPH09505308A (en)
AT (1)ATE212830T1 (en)
AU (2)AU684324B2 (en)
CA (2)CA2176716C (en)
DE (1)DE69429820T3 (en)
DK (1)DK0729353T4 (en)
ES (1)ES2172574T5 (en)
PT (1)PT729353E (en)
WO (1)WO1995013799A1 (en)

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US5654008A (en)1997-08-05
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