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CA2119253A1 - Medication Vehicles Made of Solid Lipid Particles (Solid Lipid Nanospheres-SLN) - Google Patents

Medication Vehicles Made of Solid Lipid Particles (Solid Lipid Nanospheres-SLN)

Info

Publication number
CA2119253A1
CA2119253A1CA 2119253CA2119253ACA2119253A1CA 2119253 A1CA2119253 A1CA 2119253A1CA 2119253CA2119253CA 2119253CA 2119253 ACA2119253 ACA 2119253ACA 2119253 A1CA2119253 A1CA 2119253A1
Authority
CA
Canada
Prior art keywords
solid lipid
sln
drug carrier
nanospheres
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2119253
Other languages
French (fr)
Other versions
CA2119253C (en
Inventor
Stefan Lucks
Rainer Muller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jagotec AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=6441225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2119253(A1)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by IndividualfiledCriticalIndividual
Publication of CA2119253A1publicationCriticalpatent/CA2119253A1/en
Application grantedgrantedCritical
Publication of CA2119253CpublicationCriticalpatent/CA2119253C/en
Anticipated expirationlegal-statusCritical
Expired - Lifetimelegal-statusCriticalCurrent

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Abstract

The invention relates to a drug carrier which comprises particles of lipid or lipid-like (lipoid) material or mixtures thereof which have a diameter of 10 nm to 10 µm and which are solid at room temperature. On account of its solid core, the drug carrier allows a controllable liberation of active substances over a longer period of time and the incorporation of hydrophilous medicinal agents into the solid core. Furthermore, the drug carrier makes a relatively quick degrading possible at which no toxic by-products are produced.
CA002119253A1991-09-181992-09-16Medication vehicles made of solid lipid particles (solid lipid nanospheres-sln)Expired - LifetimeCA2119253C (en)

Applications Claiming Priority (2)

Application NumberPriority DateFiling DateTitle
DEP4131562.61991-09-18
DE4131562ADE4131562A1 (en)1991-09-181991-09-18 SOLID LIPID PARTICLE SOLID LIPID NANOSPHERES (SLN)

Publications (2)

Publication NumberPublication Date
CA2119253A1true CA2119253A1 (en)1993-04-01
CA2119253C CA2119253C (en)1998-11-03

Family

ID=6441225

Family Applications (1)

Application NumberTitlePriority DateFiling Date
CA002119253AExpired - LifetimeCA2119253C (en)1991-09-181992-09-16Medication vehicles made of solid lipid particles (solid lipid nanospheres-sln)

Country Status (13)

CountryLink
EP (1)EP0605497B2 (en)
JP (1)JP2683575B2 (en)
KR (1)KR0141504B1 (en)
AT (1)ATE135567T1 (en)
AU (1)AU672177B2 (en)
CA (1)CA2119253C (en)
CZ (1)CZ289253B6 (en)
DE (2)DE4131562A1 (en)
DK (1)DK0605497T4 (en)
ES (1)ES2085035T5 (en)
GR (2)GR3019750T3 (en)
HU (1)HU227680B1 (en)
WO (1)WO1993005768A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US8029823B2 (en)1999-06-142011-10-04Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US8445024B2 (en)2005-10-252013-05-21Evonik Degussa GmbhPreparations containing hyperbranched polymers
US8663692B1 (en)1999-05-072014-03-04Pharmasol GmbhLipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
US8895064B2 (en)1999-06-142014-11-25Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US8911788B2 (en)2003-03-242014-12-16Capsugel France SASGalenical system for active transport, method for preparation and use
US10660858B2 (en)2011-09-072020-05-26Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition

Families Citing this family (48)

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DE4308282C2 (en)*1993-03-161994-12-22Beiersdorf Ag Galenic matrices preferably in the form of microspheres
US5576016A (en)*1993-05-181996-11-19Pharmos CorporationSolid fat nanoemulsions as drug delivery vehicles
DE4336407A1 (en)*1993-10-211995-04-27Rotring Int Gmbh Waterproof cosmetics
EP0826063A1 (en)*1995-04-251998-03-04Vical IncorporatedSingle-vial formulations of dna/lipid complexes
US6465016B2 (en)1996-08-222002-10-15Research Triangle PharmaceuticalsCyclosporiine particles
US7255877B2 (en)1996-08-222007-08-14Jagotec AgFenofibrate microparticles
WO1999012571A1 (en)*1997-09-051999-03-18Maruho KabushikikaishaNanocapsule preparations for treating intraarticular diseases
IT1296914B1 (en)1997-12-011999-08-03Maria Rosa Gasco PHARMACEUTICAL COMPOSITION INCLUDING MICROPARTICLES SUITABLE FOR TRANSMUCOSAL PASSAGE AND OVERCOMING THE BARRIER
US6979456B1 (en)1998-04-012005-12-27Jagotec AgAnticancer compositions
ES2216517T3 (en)1998-05-292004-10-16Skyepharma Canada Inc. COMPOSITIONS OF THERMOPROTEGED MICROCAPSULES AND PROCEDURE FOR THE TERMINAL STERILIZATION WITH STEAM.
WO2000030616A1 (en)1998-11-202000-06-02Rtp Pharma Inc.Dispersible phospholipid stabilized microparticles
DE19856432A1 (en)1998-12-082000-06-15Basf Ag Nanoparticulate core-shell systems and their use in pharmaceutical and cosmetic preparations
WO2001003652A2 (en)*1999-07-132001-01-18Pharmasol GmbhUv radiation reflecting or absorbing agents, protecting against harmful uv radiation and reinforcing the natural skin barrier
EP1322343A4 (en)*2000-09-292006-08-16Salvona LlcMulti component controlled release system for sanitary paper products
EP1269994A3 (en)2001-06-222003-02-12Pfizer Products Inc.Pharmaceutical compositions comprising drug and concentration-enhancing polymers
KR20010090030A (en)*2001-08-092001-10-18임정옥Manufacturing and synergic effect of topical anesthetic formula consisted of mixed local anesthetics
KR100452165B1 (en)*2002-01-292004-10-08주식회사 태평양Oil-in-Water type nano-emulsion comprising a lecithin and an anionic surfactant for cosmetic, dermatological, and pharmaceutical vehicles containing thereof
DE10312763A1 (en)2003-03-212004-09-30IFAC Institut für angewandte Colloidtechnologie GmbH & Co. KG Process for the preparation of an SLN dispersion
ATE476954T1 (en)2003-05-072010-08-15Kemira Pigments Oy COMPOSITIONS FOR THE TARGETED RELEASE OF FRAGRANCES AND FLAVORS
FR2864900B1 (en)*2004-01-092007-10-12Oreal AQUEOUS DISPERSION OF NANOCAPSULES WITH OILY HEART
CA2560900A1 (en)*2004-03-262005-10-06Cell Therapeutics Europe S.R.L.Nanoparticle formulations of platinum compounds
EP1674081A1 (en)2004-12-232006-06-28KTB Tumorforschungsgesellschaft mbHPreparation of lipid based nano-particles with a dual asymetric centrifuge
JP4533185B2 (en)*2005-02-242010-09-01花王株式会社 Solid lipid particle formulation
RU2409352C2 (en)*2005-05-052011-01-20САНОФИ-АВЕНТИС Ю.Эс. ЭлЭлСиStable compositions of nanoparticles
ITMI20061274A1 (en)*2006-06-302008-01-01Consiglio Nazionale Ricerche LIPID NANOPARTICELLAR VECTORS CONTAINING RELIEF AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
EP2099420B8 (en)2006-11-172017-03-15PharmaSol GmbHNanocrystals for use in topical cosmetic formulations and method of production thereof
EP1982698A1 (en)*2007-04-182008-10-22Evonik Degussa GmbHPreparations for controlled release of natural bioactive materials
EP2108361A1 (en)*2008-04-092009-10-14ROVI Cosmetics International GmbHEmulgating microparticles made of lipids for stabilising lipophilic agents for cosmetic use
EP2218447B1 (en)2008-11-042017-04-19PharmaSol GmbHCompositions containing lipid micro- or nanoparticles for the enhancement of the dermal action of solid particles
FR2950253B1 (en)2009-09-242011-09-23Ethypharm Sa LIPID NANOCAPSULES, PREPARATION METHOD AND USE AS MEDICAMENT
ES2384060B1 (en)2010-03-242013-09-23Lipotec S.A. LIPID NANOPARTICLES CAPSULES.
GB201021937D0 (en)*2010-12-242011-02-02Reckitt & Colman OverseasSkin sanitizer compositions comprising alcohol based emulsion
JP5940556B2 (en)2010-12-282016-06-29ユニリーバー・ナームローゼ・ベンノートシヤープ Method for producing emulsion
JP2014508796A (en)2011-03-242014-04-10レオ ファーマ アクティーゼルスカブ Composition comprising lipid nanoparticles and corticosteroid or vitamin D derivative
DE102011018499A1 (en)2011-04-232012-10-25Emc Microcollections Gmbh Topical nanoparticle vaccine for the immune stimulation of dendritic cells in the skin
DE102011116069A1 (en)2011-10-182013-04-18Dr. Rimpler Gmbh Lipid nanoparticle dispersion, process for its preparation and its use
ITBO20130376A1 (en)2013-07-182015-01-19Ferbi Srl METHOD FOR THE PREPARATION OF SOLID LIPID NANOPARTICLES CONTAINING ANTIBODIES IN THE FORM OF A IONIAN COUPLE, THROUGH THE COACERVATION TECHNIQUE OF FATTY ACIDS
CA3050535C (en)*2014-12-152021-11-09Richard Clark KaufmanMethods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of anti-inflammatory nutraceuticals
WO2016144376A1 (en)2015-03-102016-09-15Nanosphere Health Sciences, LlcLipid nanoparticle compositions and methods as carriers of cannabinoids in standardized precision-metered dosage forms
CZ307681B6 (en)2016-02-292019-02-13Ústav makromolekulární chemie AV ČR, v. v. i.A photoactivatable nanoparticle for photodynamic applications, the method of its preparation, a pharmaceutical composition comprising it and their use
WO2019116062A1 (en)2017-12-122019-06-20Lead Biotherapeutics Ltd.Solid lipid nanoparticle for intracellular release of active substances and method for production the same
US11504327B1 (en)2019-01-212022-11-22Eric MorrisonMethod of preparing nanoparticles by hot-melt extrusion
IT201900009258A1 (en)2019-06-172020-12-17R Bio Transfer S R L METHOD FOR THE PREPARATION OF LIPID NANOPARTICLES
IT201900013353A1 (en)2019-07-302021-01-30Univ Della Calabria Bergamot essential oil delivery system based on nanotechnologies, method of preparation of the system and its uses.
US20230000980A1 (en)2021-06-302023-01-05Novocure GmbhCompositions and methods for using alternating electric fields to disrupt lipid capsules
IT202100023570A1 (en)2021-09-132023-03-13Bioema S R L S Biotecnologia Energia Mat Ambiente METHOD FOR THE PREPARATION OF LIPID NANOPARTICLES
DE202023100649U1 (en)2023-02-102023-03-22Cineolux Gmbh Dispersion and preparation for topical use
DE102023103292A1 (en)2023-02-102024-08-14Cineolux Gmbh Dispersion and preparation for topical use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
DE3421468A1 (en)*1984-06-081985-12-19Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim LIPID NANOPELLETS AS A CARRIER SYSTEM FOR MEDICINAL PRODUCTS FOR PERORAL USE
AU645003B2 (en)*1988-11-081994-01-06Takeda Chemical Industries Ltd.Sustained release preparations
LU87410A1 (en)*1988-12-201990-07-10Cird COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING POLYMERIC OR FATTY BODY MICROSPHERES CHARGED WITH AT LEAST ONE ACTIVE PRODUCT
FR2651680B1 (en)*1989-09-141991-12-27Medgenix Group Sa NOVEL PROCESS FOR THE PREPARATION OF LIPID MICROPARTICLES.
FR2657257B1 (en)*1990-01-191994-09-02Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF DRUGS IN THE FORM OF PEARLS.

Cited By (13)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
US8663692B1 (en)1999-05-072014-03-04Pharmasol GmbhLipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
US9532954B2 (en)1999-06-142017-01-03Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical compositions
USRE43799E1 (en)1999-06-142012-11-13Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US8293273B2 (en)1999-06-142012-10-23Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US8784888B2 (en)1999-06-142014-07-22Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US8895064B2 (en)1999-06-142014-11-25Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US9320716B2 (en)1999-06-142016-04-26Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical compositions
US8029823B2 (en)1999-06-142011-10-04Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US9592203B2 (en)1999-06-142017-03-14Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US9737489B2 (en)1999-06-142017-08-22Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition
US8911788B2 (en)2003-03-242014-12-16Capsugel France SASGalenical system for active transport, method for preparation and use
US8445024B2 (en)2005-10-252013-05-21Evonik Degussa GmbhPreparations containing hyperbranched polymers
US10660858B2 (en)2011-09-072020-05-26Cosmo Technologies LimitedControlled release and taste masking oral pharmaceutical composition

Also Published As

Publication numberPublication date
KR0141504B1 (en)1998-06-01
EP0605497B2 (en)1999-04-14
CZ289253B6 (en)2001-12-12
AU672177B2 (en)1996-09-26
CZ59694A3 (en)1994-07-13
AU2561592A (en)1993-04-27
ES2085035T3 (en)1996-05-16
DE59205783D1 (en)1996-04-25
DK0605497T3 (en)1996-08-05
CA2119253C (en)1998-11-03
JP2683575B2 (en)1997-12-03
HU227680B1 (en)2011-11-28
ATE135567T1 (en)1996-04-15
EP0605497B1 (en)1996-03-20
JPH06510772A (en)1994-12-01
HU9400779D0 (en)1994-06-28
WO1993005768A1 (en)1993-04-01
EP0605497A1 (en)1994-07-13
GR3019750T3 (en)1996-07-31
HUT75165A (en)1997-04-28
DK0605497T4 (en)1999-10-25
ES2085035T5 (en)1999-06-16
DE4131562A1 (en)1993-03-25
GR3030291T3 (en)1999-09-30

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