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BR112017008660A2 - formulação de solução de proteína estável contendo alta concentração de um anticorpo anti-vegf - Google Patents

formulação de solução de proteína estável contendo alta concentração de um anticorpo anti-vegf

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Publication number
BR112017008660A2
BR112017008660A2BR112017008660ABR112017008660ABR112017008660A2BR 112017008660 A2BR112017008660 A2BR 112017008660A2BR 112017008660 ABR112017008660 ABR 112017008660ABR 112017008660 ABR112017008660 ABR 112017008660ABR 112017008660 A2BR112017008660 A2BR 112017008660A2
Authority
BR
Brazil
Prior art keywords
high concentration
protein solution
formulation containing
containing high
vegf antibody
Prior art date
Application number
BR112017008660A
Other languages
English (en)
Inventor
Kulshreshtha Alok
Boring Charles
Zhang Huixiang
Alani Laman
Wan Li
Zeng Yuhong
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filedlitigationCriticalhttps://patents.darts-ip.com/?family=54697654&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112017008660(A2)"Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AgfiledCriticalNovartis Ag
Publication of BR112017008660A2publicationCriticalpatent/BR112017008660A2/pt

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Abstract

a presente invenção proporciona anticorpos anti-vegf formulados como composições farmacêuticas aquosas, de alta concentração, adequados para uma injeção, preferivelmente uma injeção intravítrea. as composições farmacêuticas aquosas são úteis para a liberação de uma alta concentração do ingrediente ativo de anticorpo para um paciente, sem altos níveis de agregação do anticorpo e sem um alto nível de matéria particulada subvisível. uma composição aquosa da invenção compreende um anticorpo tendo uma concentração de pelo menos 50 mg/ml. uma composição farmacêutica aquosa da invenção inclui um açúcar, um agente de tamponamento, e um tensoativo.
BR112017008660A2014-11-072015-11-06formulação de solução de proteína estável contendo alta concentração de um anticorpo anti-vegfBR112017008660A2 (pt)

Applications Claiming Priority (3)

Application NumberPriority DateFiling DateTitle
US201462076770P2014-11-072014-11-07
US201462088061P2014-12-052014-12-05
PCT/US2015/059571WO2016073915A1 (en)2014-11-072015-11-06Stable protein solution formulation containing high concentration of an anti-vegf antibody

Publications (1)

Publication NumberPublication Date
BR112017008660A2true BR112017008660A2 (pt)2017-12-26

Family

ID=54697654

Family Applications (2)

Application NumberTitlePriority DateFiling Date
BR112017008660ABR112017008660A2 (pt)2014-11-072015-11-06formulação de solução de proteína estável contendo alta concentração de um anticorpo anti-vegf
BR112017008093-1ABR112017008093A2 (pt)2014-11-072015-11-06processos para tratamento de doenças oculares

Family Applications After (1)

Application NumberTitlePriority DateFiling Date
BR112017008093-1ABR112017008093A2 (pt)2014-11-072015-11-06processos para tratamento de doenças oculares

Country Status (24)

CountryLink
US (5)US10689438B2 (pt)
EP (2)EP3215123A1 (pt)
JP (6)JP6753848B2 (pt)
KR (4)KR20170082526A (pt)
CN (3)CN107635580A (pt)
AU (6)AU2015342818B2 (pt)
BR (2)BR112017008660A2 (pt)
CA (2)CA2966646A1 (pt)
CL (2)CL2017001115A1 (pt)
CO (1)CO2017004596A2 (pt)
EA (1)EA201790989A1 (pt)
EC (1)ECSP17034829A (pt)
GT (1)GT201700096A (pt)
IL (5)IL251642B (pt)
MX (3)MX383399B (pt)
MY (2)MY193913A (pt)
NZ (1)NZ730821A (pt)
PE (1)PE20170780A1 (pt)
PH (3)PH12021550147A1 (pt)
RU (1)RU2722643C2 (pt)
SG (3)SG10201913565RA (pt)
TN (1)TN2017000128A1 (pt)
TW (4)TWI705827B (pt)
WO (2)WO2016073915A1 (pt)

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TWI806150B (zh)2023-06-21
GT201700096A (es)2019-10-10
KR20240161204A (ko)2024-11-12
RU2722643C2 (ru)2020-06-02
NZ730821A (en)2019-11-29
AU2020220210B2 (en)2022-01-20
MX2021006768A (es)2021-07-15
IL280087B (en)2022-02-01
PH12021550147A1 (en)2023-01-23
IL280087A (en)2021-03-01
PE20170780A1 (es)2017-07-04
AU2018278870A1 (en)2019-01-03
AU2015342815A1 (en)2017-05-11
US20160130337A1 (en)2016-05-12
PH12017500843A1 (en)2017-10-30
EP3215122A1 (en)2017-09-13
AU2018278870B2 (en)2020-05-28
EP3215123A1 (en)2017-09-13
US12049495B2 (en)2024-07-30
US11098110B2 (en)2021-08-24
TW202146049A (zh)2021-12-16
JP2020193212A (ja)2020-12-03
AU2020220210A1 (en)2020-10-01
IL251696A0 (en)2017-06-29
MX2017005875A (es)2017-06-26
KR20230066649A (ko)2023-05-16
KR20170076781A (ko)2017-07-04
CN106999581A (zh)2017-08-01
PH12017500844A1 (en)2017-10-30
RU2020114917A3 (pt)2022-01-17
RU2017119647A (ru)2018-12-07
JP7080263B2 (ja)2022-06-03
CO2017004596A2 (es)2017-08-31
MY183807A (en)2021-03-16
MX383399B (es)2025-03-13
US20160340420A1 (en)2016-11-24
JP6667519B2 (ja)2020-03-18
SG11201702909QA (en)2017-05-30
US10689438B2 (en)2020-06-23
US20210340242A1 (en)2021-11-04
ECSP17034829A (es)2019-02-28
JP2025004075A (ja)2025-01-14
JP2017538674A (ja)2017-12-28
PH12017500844B1 (en)2021-05-05
SG10201913565RA (en)2020-02-27
WO2016073915A1 (en)2016-05-12
CL2017001115A1 (es)2018-01-26
CN107635580A (zh)2018-01-26
IL283561A (en)2021-07-29
JP2020079242A (ja)2020-05-28
CN114081951A (zh)2022-02-25
KR102588846B1 (ko)2023-10-16
IL251642B (en)2021-02-28
EA201790989A1 (ru)2017-09-29
KR102724014B1 (ko)2024-10-31
WO2016073918A1 (en)2016-05-12
AU2018274882A1 (en)2018-12-20
IL251642A0 (en)2017-06-29
CL2017001117A1 (es)2018-01-26
JP6753848B2 (ja)2020-09-09
RU2017119647A3 (pt)2019-05-29
US10035850B2 (en)2018-07-31
TN2017000128A1 (en)2018-10-19
KR20170082526A (ko)2017-07-14
TWI705827B (zh)2020-10-01
TW202103735A (zh)2021-02-01
US20180298092A1 (en)2018-10-18
US20200270336A1 (en)2020-08-27
AU2018274882B2 (en)2020-07-09
MY193913A (en)2022-11-01
IL283561B (en)2022-01-01
CA2966646A1 (en)2016-05-12
RU2020114917A (ru)2020-05-22
JP2022141923A (ja)2022-09-29
BR112017008093A2 (pt)2018-03-13
AU2020244614A1 (en)2020-11-05
CA2966758A1 (en)2016-05-12
SG11201702954XA (en)2017-05-30
TWI738632B (zh)2021-09-11
AU2020244614B2 (en)2023-06-01
AU2015342815B2 (en)2018-12-13
AU2015342818A1 (en)2017-05-11
TWI761959B (zh)2022-04-21
AU2015342818B2 (en)2019-01-03
TW201625306A (zh)2016-07-16
TW201625221A (zh)2016-07-16
MX2017005874A (es)2017-06-26
IL265497B (en)2021-06-30
IL265497A (en)2019-05-30
JP2017534638A (ja)2017-11-24
MX383808B (es)2025-03-14

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B07DTechnical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text:DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07ENotification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06UPreliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07AApplication suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07AApplication suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09BPatent application refused [chapter 9.2 patent gazette]
B12BAppeal against refusal [chapter 12.2 patent gazette]

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