Movatterモバイル変換


[0]ホーム

URL:


AU2002351077A1 - Oligonucleotides modified with novel alpha-l-rna analogues - Google Patents

Oligonucleotides modified with novel alpha-l-rna analogues

Info

Publication number
AU2002351077A1
AU2002351077A1AU2002351077AAU2002351077AAU2002351077A1AU 2002351077 A1AU2002351077 A1AU 2002351077A1AU 2002351077 AAU2002351077 AAU 2002351077AAU 2002351077 AAU2002351077 AAU 2002351077AAU 2002351077 A1AU2002351077 A1AU 2002351077A1
Authority
AU
Australia
Prior art keywords
novel alpha
oligonucleotides modified
rna analogues
analogues
rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002351077A
Inventor
Jesper Wengel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exiqon AS
Original Assignee
Exiqon AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exiqon ASfiledCriticalExiqon AS
Publication of AU2002351077A1publicationCriticalpatent/AU2002351077A1/en
Abandonedlegal-statusCriticalCurrent

Links

Classifications

Landscapes

AU2002351077A2001-11-052002-11-05Oligonucleotides modified with novel alpha-l-rna analoguesAbandonedAU2002351077A1 (en)

Applications Claiming Priority (5)

Application NumberPriority DateFiling DateTitle
US33744701P2001-11-052001-11-05
DKPA2001016402001-11-05
DKPA2001016402001-11-05
US60/337,4472001-11-05
PCT/IB2002/005080WO2003039523A2 (en)2001-11-052002-11-05OLIGONUCLEOTIDES MODIFIED WITH NOVEL α-L-RNA ANALOGUES

Publications (1)

Publication NumberPublication Date
AU2002351077A1true AU2002351077A1 (en)2003-05-19

Family

ID=29585604

Family Applications (1)

Application NumberTitlePriority DateFiling Date
AU2002351077AAbandonedAU2002351077A1 (en)2001-11-052002-11-05Oligonucleotides modified with novel alpha-l-rna analogues

Country Status (2)

CountryLink
AU (1)AU2002351077A1 (en)
WO (1)WO2003039523A2 (en)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
USRE44779E1 (en)1997-03-072014-02-25Santaris Pharma A/SBicyclonucleoside and oligonucleotide analogues
MY164523A (en)2000-05-232017-12-29Univ Degli Studi CagliariMethods and compositions for treating hepatitis c virus
EA007867B1 (en)2000-05-262007-02-27Айденикс (Кайман) ЛимитедMethods and compositions for treating flaviviruses and pestiviruses
GB0114286D0 (en)2001-06-122001-08-01Hoffmann La RocheNucleoside Derivatives
CN101172993A (en)2002-06-282008-05-07埃迪尼克斯(开曼)有限公司2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
CA2489552A1 (en)2002-06-282004-01-08Idenix (Cayman) Limited2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
CA2506129C (en)2002-11-152015-02-17Idenix (Cayman) Limited2'-branched nucleosides and flaviviridae mutation
EP1585529A4 (en)2002-12-122008-05-28Idenix Cayman LtdProcess for the production of 2'-branched nucleosides
CA2529793C (en)*2003-06-202015-05-05Exiqon A/SProbes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same
US20050089889A1 (en)2003-06-202005-04-28Ramsing Niels B.Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same
ES2327252T3 (en)2004-08-232009-10-27F. Hoffmann-La Roche Ag 4'-AZIDO ANTIVIRAL NUCLEOSIDS.
US8071306B2 (en)2005-01-252011-12-06Merck Sharp & Dohme Corp.Methods for quantitating small RNA molecules
NZ575889A (en)2006-10-102011-09-30Medivir AbHcv nucleoside inhibitor
WO2007054100A2 (en)*2006-11-132007-05-18Santaris Pharma A/SLna nucleoside phosphoramidates
WO2009044392A2 (en)2007-10-032009-04-09Quark Pharmaceuticals, Inc.Novel sirna structures
BRPI0820738A2 (en)2007-12-142015-06-16Minitube America Inc Gender-specific separation of sperm and embryo cells
US8227431B2 (en)2008-03-172012-07-24Hetero Drugs LimitedNucleoside derivatives
KR20110128947A (en)2009-03-202011-11-30앨리오스 바이오파마 인크. Substituted Nucleoside and Nucleotide Analogs
WO2011032034A2 (en)2009-09-102011-03-17University Of IdahoNucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids
EP2616555B1 (en)2010-09-162017-11-08Gen-Probe IncorporatedCapture probes immobilizable via l-nucleotide tail
CA2810928A1 (en)2010-09-222012-03-29Alios Biopharma, Inc.Substituted nucleotide analogs
ES2701020T3 (en)2010-09-222019-02-20Alios Biopharma Inc Azido nucleosides and nucleotide analogs
DE12722942T1 (en)2011-03-312021-09-30Modernatx, Inc. RELEASE AND FORMULATION OF MANIPULATED NUCLEIC ACIDS
WO2013013068A2 (en)2011-07-192013-01-24University Of IdahoEmbodiments of a probe and method for targeting nucleic acids
PT2794627T (en)2011-12-222018-12-19Janssen Biopharma IncSubstituted nucleosides, nucleotides and analogs thereof
WO2013096680A1 (en)2011-12-222013-06-27Alios Biopharma, Inc.Substituted phosphorothioate nucleotide analogs
US9441007B2 (en)2012-03-212016-09-13Alios Biopharma, Inc.Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en)2012-03-212020-08-25Janssen Biopharma, Inc.Substituted nucleosides, nucleotides and analogs thereof
WO2013142124A1 (en)2012-03-212013-09-26Vertex Pharmaceuticals IncorporatedSolid forms of a thiophosphoramidate nucleotide prodrug
EP2827876A4 (en)2012-03-222015-10-28Alios Biopharma IncPharmaceutical combinations comprising a thionucleotide analog
US9422323B2 (en)2012-05-252016-08-23Janssen Sciences Ireland UcUracyl spirooxetane nucleosides
ES2671478T3 (en)2012-08-312018-06-06Novartis Ag 2'-ethinyl nucleoside derivatives for the treatment of viral infections
LT2935303T (en)2012-12-212021-03-25Janssen Biopharma, Inc.4'-fluoro-nucleosides, 4'-fluoro-nucleotides and analogs thereof for the treatment of hcv
WO2014100934A1 (en)2012-12-242014-07-03Merck Sharp & Dohme Corp.Glycosidase inhibitors and uses thereof
WO2014144767A1 (en)2013-03-152014-09-18Moderna Therapeutics, Inc.Ion exchange purification of mrna
EP4279610A3 (en)2013-03-152024-01-03ModernaTX, Inc.Ribonucleic acid purification
WO2014152027A1 (en)2013-03-152014-09-25Moderna Therapeutics, Inc.Manufacturing methods for production of rna transcripts
US10077439B2 (en)2013-03-152018-09-18Modernatx, Inc.Removal of DNA fragments in mRNA production process
PT3019619T (en)2013-07-112021-11-11Modernatx Inc COMPOSITIONS COMPRISING SYNTHETIC POLYNUCLEOTIDES ENCODING SYNTHETIC CRISPR AND SGARN-RELATED PROTEINS AND METHODS OF USE
WO2015051169A2 (en)2013-10-022015-04-09Moderna Therapeutics, Inc.Polynucleotide molecules and uses thereof
CN105829333A (en)2013-10-112016-08-03艾丽奥斯生物制药有限公司Substituted nucleosides, nucleotides and analogs thereof
US10286086B2 (en)2014-06-192019-05-14Modernatx, Inc.Alternative nucleic acid molecules and uses thereof
AU2015289656A1 (en)2014-07-162017-02-16Modernatx, Inc.Circular polynucleotides
CA2978085C (en)2015-03-062023-01-17Atea Pharmaceuticals, Inc..beta.-d-2'-deoxy-2'-.alpha.-fluoro-2'-.beta.-c-substituted-2-modified-n6-substituted purine nucleotides for hcv treatment
CN105085356B (en)*2015-08-262018-09-07中国科学院化学研究所Small paper mulberry alkaloid compound and its preparation method and application
CN105085357B (en)*2015-08-262018-04-13中国科学院化学研究所Small paper mulberry alkaloid compound and its preparation method and application
TWI870767B (en)2015-08-262025-01-21比利時商健生藥品公司Novel 6-6 bicyclic aromatic ring substituted nucleoside analogues for use as prmt5 inhibitors
WO2017049286A1 (en)*2015-09-172017-03-23Moderna Therapeutics, Inc.Polynucleotides containing a morpholino linker
ES2908449T3 (en)2015-09-172022-04-29Modernatx Inc Polynucleotides that contain a stabilizing tail region
JP6909799B2 (en)2016-03-102021-07-28ヤンセン ファーマシューティカ エヌ.ベー. Substituted nucleoside analogs for use as PRMT5 inhibitors
WO2017223176A1 (en)2016-06-242017-12-28Modernatx, Inc.Methods and apparatus for filtration
WO2018035380A1 (en)2016-08-172018-02-22Solstice Biologics, Ltd.Polynucleotide constructs
RS62943B1 (en)2016-09-072022-03-31Atea Pharmaceuticals Inc2'-substituted-n6-substituted purine nucleotides for rna virus treatment
CN109803971B (en)2016-10-032022-10-28詹森药业有限公司Monocyclic and bicyclic substituted carbanucleoside analogs as PRMT5 inhibitors
CA3197567A1 (en)2017-02-012018-08-09Atea Pharmaceuticals, Inc.Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus
IL268842B2 (en)2017-02-272024-09-01Janssen Pharmaceutica Nv Use of biomarkers in identifying cancer patients who will respond to treatment with a PRMT5 inhibitor
WO2019006455A1 (en)2017-06-302019-01-03Solstice Biologics, Ltd.Chiral phosphoramidite auxiliaries and methods of their use
CN107973830B (en)*2017-11-232020-06-05中国科学院成都生物研究所Total synthesis method of neooxytocin
BR112020010815A2 (en)2017-12-082020-11-10Janssen Pharmaceutica Nv spirobicyclic analogs
KR20200140865A (en)2018-04-102020-12-16아테아 파마슈티컬즈, 인크. Treatment of HCV-infected patients with cirrhosis
WO2020072991A1 (en)*2018-10-052020-04-09Ionis Pharmaceuticals, Inc.Modified oligomeric compounds and uses thereof
CN114072407A (en)2019-04-022022-02-18阿里戈斯治疗公司Compounds targeting PRMT5
TW202112375A (en)2019-06-062021-04-01比利時商健生藥品公司Methods of treating cancer using prmt5 inhibitors
WO2021030763A1 (en)*2019-08-152021-02-18Ionis Pharmaceuticals, Inc.Modified oligomeric compounds and uses thereof
CA3162717A1 (en)*2019-11-272021-06-03Alnylam Pharmaceuticals, Inc.Synthesis of 3'-rna oligonucleotides
TWI874791B (en)2020-02-182025-03-01美商基利科學股份有限公司Antiviral compounds
TWI883391B (en)2020-02-182025-05-11美商基利科學股份有限公司Antiviral compounds
CA3171648A1 (en)2020-02-182021-08-26Gilead Sciences, Inc.Antiviral compounds
US10874687B1 (en)2020-02-272020-12-29Atea Pharmaceuticals, Inc.Highly active compounds against COVID-19
CA3216162A1 (en)2021-04-162022-10-20Gilead Sciences, Inc.Methods of preparing carbanucleosides using amides
US11649260B2 (en)2021-06-182023-05-16Hongene Biotech CorporationFunctionalized N-acetylgalactosamine nucleosides
AU2022328698B2 (en)2021-08-182025-02-20Gilead Sciences, Inc.Phospholipid compounds and methods of making and using the same
EP4396193A4 (en)2021-08-302025-07-02Hongene Biotech Corp Functionalized N-acetylgalactosamine analogues
WO2023114746A1 (en)2021-12-152023-06-22Hongene Biotech CorporationFunctionalized n-acetylgalactosamine analogs
US12116382B2 (en)2022-11-282024-10-15Hongene Biotech CorporationFunctionalized N-acetylgalactosamine analogs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication numberPriority datePublication dateAssigneeTitle
FR2636633A1 (en)*1988-09-201990-03-23Centre Nat Rech Scient PROCESS FOR SYNTHESIS OF ALPHA OLIGORIBONUCLEOTIDES AND COMPOUNDS USEFUL IN THE PROCESS
US5559101A (en)*1994-10-241996-09-24Genencor International, Inc.L-ribofuranosyl nucleosides
ATE293123T1 (en)*1997-09-122005-04-15Exiqon As BI- AND TRI-CYCLIC - NUCLEOSIDE, NUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGS
CA2368135C (en)*1999-03-182010-06-08Exiqon A/SXylo-lna analogues
US7053207B2 (en)*1999-05-042006-05-30Exiqon A/SL-ribo-LNA analogues
JP2003511016A (en)*1999-10-042003-03-25エクシコン エ/エス Design of High Affinity RNase H to Replenish Oligonucleotides

Also Published As

Publication numberPublication date
WO2003039523A2 (en)2003-05-15
WO2003039523A3 (en)2003-12-04

Similar Documents

PublicationPublication DateTitle
AU2002351077A1 (en)Oligonucleotides modified with novel alpha-l-rna analogues
GB0128526D0 (en)Nucleotide analogues
AU2002358463A1 (en)Oligonucleotide analogues comprising intercalator pseudonucleotides
AU2002313565A1 (en)Putter-heads
AU2002319532A1 (en)Feeding-bottles
AU2002330025A1 (en)Atlastin
AU2002313943A1 (en)Electromobile
AU2002330790A1 (en)Ferro-sticker
AU2002226571A1 (en)Biligands
AU2001100406A4 (en)DriverSMS
AU2002313073A1 (en)Phytocystatin
AU2002257925A1 (en)Numberplates
AU2002333362A1 (en)Flat structure
AU2001100532A4 (en)FonePark
AU2001100522A4 (en)e-Trans
AU2002100746A4 (en)Adrail
AU2001100214A4 (en)Dolly-trolley
AU2002302458A1 (en)Paint-can with bruswiper
AU2002235828A1 (en)Transom-mullion structure
AU2002258273A1 (en)Drain-outlet structure
AU2002246370A1 (en)Flat unit structure
AUPR383801A0 (en)Increased superannuation
AU2002305440A1 (en)Piperazinyl-isatins
AU2002312925A1 (en)5-ethyl-imidazotriazinones
AU2002256542A1 (en)Motor-vehicle-tank-sender-unit

Legal Events

DateCodeTitleDescription
MK6Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase

[8]ページ先頭

©2009-2025 Movatter.jp