| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24946500P | 2000-11-20 | 2000-11-20 | |
| US60/249,465 | 2000-11-20 | ||
| PCT/US2001/043294WO2002040481A2 (en) | 2000-11-20 | 2001-11-20 | Adenine based inhibitors of adenylyl cyclase, pharmaceutical compositions and method of use thereof |
| Publication Number | Publication Date |
|---|---|
| AU2002239277A1true AU2002239277A1 (en) | 2002-05-27 |
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002239277AAbandonedAU2002239277A1 (en) | 2000-11-20 | 2001-11-20 | Adenine based inhibitors of adenylyl cyclase, pharmaceutical compositions and method of use thereof |
| Country | Link |
|---|---|
| US (1) | US6887880B2 (en) |
| AU (1) | AU2002239277A1 (en) |
| WO (1) | WO2002040481A2 (en) |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060252774A1 (en)* | 2002-05-02 | 2006-11-09 | Vatner Stephen F | Regulation of type 5 adenylyl cyclase for treatment of neurodegenerative and cardiac diseases |
| GEP20084393B (en) | 2003-04-24 | 2008-06-10 | Incyte Corp | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| TWI414525B (en) | 2004-03-26 | 2013-11-11 | Dainippon Sumitomo Pharma Co | 9-substituted-8-oxoadenine compound |
| JPWO2005092892A1 (en)* | 2004-03-26 | 2008-02-14 | 大日本住友製薬株式会社 | 8-Oxoadenine compounds |
| US8138172B2 (en) | 2006-07-05 | 2012-03-20 | Astrazeneca Ab | 8-oxoadenine derivatives acting as modulators of TLR7 |
| TW200831105A (en)* | 2006-12-14 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| US8067413B2 (en)* | 2007-03-19 | 2011-11-29 | Astrazeneca Ab | 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators |
| US8063051B2 (en)* | 2007-03-19 | 2011-11-22 | Astrazeneca Ab | 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7) modulators |
| AR065784A1 (en)* | 2007-03-20 | 2009-07-01 | Dainippon Sumitomo Pharma Co | DERIVATIVES OF 8-OXO ADENINE, DRUGS THAT CONTAIN THEM AND USES AS THERAPEUTIC AGENTS FOR ALLERGIC, ANTIVIRAL OR ANTIBACTERIAL DISEASES. |
| US8044056B2 (en) | 2007-03-20 | 2011-10-25 | Dainippon Sumitomo Pharma Co., Ltd. | Adenine compound |
| ES2393037T3 (en)* | 2007-05-08 | 2012-12-18 | Astrazeneca Ab | Imidazoquinolines with immunomodulatory properties |
| BRPI0813176A2 (en)* | 2007-06-15 | 2014-12-30 | Mission Pharma Co | MOLECULES AND COMPOSITIONS TO INHIBIT EDEMA AND ADENYLIL CYCLASE FACTOR |
| EP3493216A1 (en)* | 2007-11-13 | 2019-06-05 | Oridion Medical 1987 Ltd. | Medical system, apparatus and method |
| PE20091156A1 (en) | 2007-12-17 | 2009-09-03 | Astrazeneca Ab | SALTS OF (3 - {[[3- (6-AMINO-2-BUTOXY-8-OXO-7,8-DIHIDRO-9H-PURIN-9-IL) PROPYL] (3-MORFOLIN-4-ILPROPIL) AMINO] METHYL} PHENYL) METHYL ACETATE |
| CA2711769A1 (en)* | 2008-01-17 | 2009-07-23 | Dainippon Sumitomo Pharma Co. Ltd. | Method for preparing adenine compound |
| JPWO2009091031A1 (en)* | 2008-01-17 | 2011-05-26 | 大日本住友製薬株式会社 | Method for producing adenine compound |
| WO2011068233A1 (en)* | 2009-12-03 | 2011-06-09 | Dainippon Sumitomo Pharma Co., Ltd. | Imidazoquinolines which act via toll - like receptors (tlr) |
| JP5978225B2 (en) | 2010-12-16 | 2016-08-24 | 大日本住友製薬株式会社 | Imidazo [4,5-c] quinolin-1-yl derivatives useful for therapy |
| DK2651943T3 (en) | 2010-12-17 | 2017-06-06 | Sumitomo Dainippon Pharma Co Ltd | purine derivatives |
| US10893824B2 (en)* | 2010-12-20 | 2021-01-19 | Cardiac Pacemakers, Inc. | Heart failure detection with a sequential classifier |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| US9394285B2 (en) | 2013-03-15 | 2016-07-19 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| CN106414446A (en)* | 2014-03-13 | 2017-02-15 | 新加坡科技研究局 | Fused pyrimidine-based hydroxamate derivatives |
| CN108558882B (en)* | 2018-04-12 | 2020-08-04 | 河南师范大学 | Method for synthesizing chiral five-membered carbocyclic purine nucleoside through [3+2] cycloaddition based on allenoic acid ester |
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224438A (en)* | 1970-07-14 | 1980-09-23 | Boehringer Mannheim Gmbh | Adenosine-5'-carboxylic acid amides |
| US3855206A (en)* | 1973-04-11 | 1974-12-17 | Abbott Lab | Adenosine-5{40 -carbohydroxamic esters |
| US4479942A (en)* | 1981-08-10 | 1984-10-30 | Fujisawa Pharmaceutical Co., Ltd. | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof |
| US5310731A (en)* | 1984-06-28 | 1994-05-10 | Whitby Research, Inc. | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents |
| DE19741739B4 (en)* | 1997-09-22 | 2006-04-27 | Nanogen Recognomics Gmbh | Supramolecular mating system, its production and use |
| Publication number | Publication date |
|---|---|
| WO2002040481A2 (en) | 2002-05-23 |
| US6887880B2 (en) | 2005-05-03 |
| WO2002040481A3 (en) | 2003-03-13 |
| US20020068745A1 (en) | 2002-06-06 |
| Publication | Publication Date | Title |
|---|---|---|
| AU2002239277A1 (en) | Adenine based inhibitors of adenylyl cyclase, pharmaceutical compositions and method of use thereof | |
| AU5699399A (en) | Pyridyl-bridgehead derivatives and their analogues, pharmaceutical compositions and their use as inhibitors of nicotinic cholinergic receptors | |
| IL160108A0 (en) | Pharmaceutical compositions containing beta-lapachone or derivatives or analogs thereof, and methods of using same | |
| HUP0303016A3 (en) | Xanthine phosphodiesterase v inhibitors, process for their preparation and pharmaceutical compositions containing them and their use | |
| HUP0302412A3 (en) | Betha-carboline derivatives useful as inhibitors of phosphodiesterase and pharmaceutical compositions containing the same | |
| HUP0300565A3 (en) | 8-quinolinxanthine and 8-isoquinolinxanthine derivatives as pde 5 inhibitors, their use, process for their preparation and pharmaceutical compositions containing them | |
| AU2003280188A1 (en) | Benzoxazin-3-ones and derivatives thereof as inhibitors of pi3k | |
| AU2002363236A1 (en) | Compounds, pharmaceutical compositions and methods of use therefor | |
| HUP0302485A3 (en) | Arylmethylamine derivatives for use as tryptase inhibitors and pharmaceutical compositions containing them | |
| HUP0402454A3 (en) | Substituted quinazoline derivatives as inhibitors of aurora kinases, process for their preparation and pharmaceutical compositions containing them | |
| NO331093B1 (en) | Somatostatin analogues, method of preparation, pharmaceutical composition and use. | |
| HUP0301683A3 (en) | Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral indopeptidase, their intermediates, process for their preparation, pharmaceutical compositions containing them and their use | |
| IL163755A (en) | 1,2,3-substituted indolizine derivatives, inhibitors of fgfs, method for making same and pharmaceutical compositions containing same | |
| PL352293A1 (en) | Derivatives of purine, method of making same and pharmaceutical compositions containing these derivatives | |
| PL375373A1 (en) | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | |
| AU2003269421A8 (en) | Hiv-integrase inhibitors, pharmaceutical compositions, and methods for their use | |
| PL356911A1 (en) | Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same | |
| AU2002216346A1 (en) | Cabergoline pharmaceutical compositions and methods of use thereof | |
| AU2003247444A1 (en) | Composition and method for cessation of nicotine cravings | |
| AU2003251695A1 (en) | Novel thiophene derivatives, preparation method thereof and pharmaceutical compositions containing same | |
| HUP0400317A3 (en) | Beta-carboline derivatives, process for their preparation, their use and pharmaceutical compositions containing them | |
| PL352280A1 (en) | Derivatives of naphthyridine, method of making same, use of same and pharmaceutical compositions containing these derivatives | |
| HUP0202988A3 (en) | Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-one derivatives and their use as lipase inhibitors, process for their preparation and pharmaceutical compositions containing them | |
| AU2001247196A1 (en) | Methods and compositions for detection of disease | |
| AU2001252711A1 (en) | Aqueous-prodrug compound comprising moiety of paclitxel or derivatives thereof, method of preparing same and pharmaceutical composition comprising same |