| US5478A (en) | | 1848-03-21 | | Cooking-stove |
| US3553452A (en) | 1969-02-17 | 1971-01-05 | Us Air Force | Time-of-flight mass spectrometer operative at elevated ion source pressures |
| CH543306A (en) | 1971-10-13 | 1973-10-31 | Hoffmann La Roche | Micropipettor |
| US3776700A (en) | 1971-12-08 | 1973-12-04 | Linbro Chem Co Inc | Serial dilution apparatus |
| US3931516A (en) | 1974-08-30 | 1976-01-06 | Nasa | Moving particle composition analyzer |
| CH583460A5 (en) | 1974-09-30 | 1976-12-31 | Balzers Patent Beteilig Ag | |
| DE2548891C3 (en) | 1975-10-31 | 1983-04-28 | Finnigan MAT GmbH, 2800 Bremen | Sample changer for mass spectrometers |
| DE2739829C2 (en) | 1977-09-03 | 1986-04-10 | Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München | Arrangement for analyzing a sample layer by bombarding it with electromagnetic radiation |
| US4139346A (en) | 1977-11-28 | 1979-02-13 | Enzo Bio Chem Incorporated | Nucleic acid and protein binding paper |
| US4218539A (en) | 1978-03-24 | 1980-08-19 | Weltman Joel K | Enzyme conjugates and method of preparation and use |
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US4461328A (en) | 1982-06-04 | 1984-07-24 | Drummond Scientific Company | Pipette device |
| DE3221681A1 (en) | 1982-06-08 | 1983-12-08 | Bayer Ag, 5090 Leverkusen | Mass spectrometer with an external sample holder |
| US5198540A (en) | 1982-10-28 | 1993-03-30 | Hubert Koster | Process for the preparation of oligonucleotides in solution |
| US5059654A (en) | 1983-02-14 | 1991-10-22 | Cuno Inc. | Affinity matrices of modified polysaccharide supports |
| US4515781A (en) | 1983-02-23 | 1985-05-07 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | 2',5'-Riboadenylate-morpholinoadenylate nucleotides |
| US4554839A (en) | 1983-10-14 | 1985-11-26 | Cetus Corporation | Multiple trough vessel for automated liquid handling apparatus |
| JPS60119067A (en) | 1983-11-30 | 1985-06-26 | Shimadzu Corp | Time-of-flight mass spectrometer |
| US4733073A (en) | 1983-12-23 | 1988-03-22 | Sri International | Method and apparatus for surface diagnostics |
| US4582789A (en) | 1984-03-21 | 1986-04-15 | Cetus Corporation | Process for labeling nucleic acids using psoralen derivatives |
| US4957858A (en) | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
| US4849077A (en) | 1984-08-06 | 1989-07-18 | Akademie Der Wissenschaften Der Ddr | Process for solid phase-sequencing of nucleic acid fragments |
| US4594506A (en) | 1984-09-10 | 1986-06-10 | Nicolet Instrument Corporation | Gas chromatograph/mass spectrometer interface |
| US4952518A (en) | 1984-10-01 | 1990-08-28 | Cetus Corporation | Automated assay machine and assay tray |
| US5118605A (en) | 1984-10-16 | 1992-06-02 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
| US4604363A (en) | 1984-10-18 | 1986-08-05 | Analytical Bio-Chemistry Laboratories Inc. | Automatic evaporator system |
| US5064754A (en) | 1984-12-14 | 1991-11-12 | Mills Randell L | Genomic sequencing method |
| US5221518A (en) | 1984-12-14 | 1993-06-22 | Mills Randell L | DNA sequencing apparatus |
| GB2177507B (en) | 1985-06-13 | 1989-02-15 | Mitsubishi Electric Corp | Laser mass spectroscopic analyzer |
| US4663944A (en) | 1985-07-12 | 1987-05-12 | Cornell Research Foundation, Inc. | Cryogenic sample stage for an ion microscope |
| US4806546A (en) | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on derivatized nylon supports |
| US4935357A (en)* | 1986-02-05 | 1990-06-19 | New England Biolabs, Inc. | Universal restriction endonuclease |
| US4826360A (en) | 1986-03-10 | 1989-05-02 | Shimizu Construction Co., Ltd. | Transfer system in a clean room |
| US5108703A (en) | 1986-03-26 | 1992-04-28 | Beckman Instruments, Inc. | Automated multi-purpose analytical chemistry processing center and laboratory work station |
| FR2597260B1 (en) | 1986-04-10 | 1988-07-15 | Univ Pasteur | METHOD FOR THE AUTOMATIC DIRECT INTRODUCTION OF SAMPLES INTO A MASS SPECTROMETER, AND DEVICE FOR CARRYING OUT SAID METHOD |
| US5000921A (en) | 1986-10-24 | 1991-03-19 | Hanaway Richard W | Multiple pipette samples |
| US4877745A (en) | 1986-11-17 | 1989-10-31 | Abbott Laboratories | Apparatus and process for reagent fluid dispensing and printing |
| FR2620049B2 (en) | 1986-11-28 | 1989-11-24 | Commissariat Energie Atomique | PROCESS FOR PROCESSING, STORING AND / OR TRANSFERRING AN OBJECT INTO A HIGHLY CLEAN ATMOSPHERE, AND CONTAINER FOR CARRYING OUT SAID METHOD |
| US5175209A (en) | 1987-01-06 | 1992-12-29 | Baylor College Of Medicine | Porous wafer for segmented synthesis of biopolymers |
| US4779467A (en) | 1987-01-28 | 1988-10-25 | Rainin Instrument Co., Inc. | Liquid-end assembly for multichannel air-displacement pipette |
| US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US5149625A (en) | 1987-08-11 | 1992-09-22 | President And Fellows Of Harvard College | Multiplex analysis of DNA |
| US5403711A (en) | 1987-11-30 | 1995-04-04 | University Of Iowa Research Foundation | Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved |
| US5670381A (en) | 1988-01-29 | 1997-09-23 | Abbott Laboratories | Devices for performing ion-capture binding assays |
| US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| US5002867A (en)* | 1988-04-25 | 1991-03-26 | Macevicz Stephen C | Nucleic acid sequence determination by multiple mixed oligonucleotide probes |
| WO1989011211A2 (en)* | 1988-05-24 | 1989-11-30 | Gesellschaft Für Biotechnologische Forschung Mbh ( | Oligonucleotide bank and process for dna sequencing |
| US5174962A (en)* | 1988-06-20 | 1992-12-29 | Genomyx, Inc. | Apparatus for determining DNA sequences by mass spectrometry |
| US5003059A (en) | 1988-06-20 | 1991-03-26 | Genomyx, Inc. | Determining DNA sequences by mass spectrometry |
| GB8816982D0 (en) | 1988-07-16 | 1988-08-17 | Probus Biomedical Ltd | Bio-fluid assay apparatus |
| US4925629A (en) | 1988-07-28 | 1990-05-15 | Bioquant, Inc. | Diagnostic device |
| FR2636738B1 (en) | 1988-09-20 | 1992-12-11 | Commissariat Energie Atomique | DNA SEQUENCING PROCESS AND INSTALLATION |
| SE464595B (en) | 1988-09-29 | 1991-05-13 | Ffv Aerotech Ab | SET A PELTIER ELEMENT WITH TWO SURFACES TO DETERMINE THE ONE OR BAD SURFACE TEMPERATURE |
| US5512439A (en) | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| US5237016A (en) | 1989-01-05 | 1993-08-17 | Siska Diagnostics, Inc. | End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids |
| US4920264A (en) | 1989-01-17 | 1990-04-24 | Sri International | Method for preparing samples for mass analysis by desorption from a frozen solution |
| AU623748B2 (en) | 1989-02-01 | 1992-05-21 | Asahi Glass Company Limited | Hydrochlorofluorocarbon azeotropic or azeotropic-like mixture |
| US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5242974A (en) | 1991-11-22 | 1993-09-07 | Affymax Technologies N.V. | Polymer reversal on solid surfaces |
| GB2233654A (en) | 1989-07-07 | 1991-01-16 | Nat Res Dev | Immobilised polynucleotides |
| GB2236186B (en) | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| US5262128A (en) | 1989-10-23 | 1993-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Array-type multiple cell injector |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| CA2036946C (en) | 1990-04-06 | 2001-10-16 | Kenneth V. Deugau | Indexing linkers |
| HU218095B (en) | 1990-05-01 | 2000-05-28 | Amgen Inc. | Process for reducing transitional contaminations in amplification processes |
| US5135870A (en) | 1990-06-01 | 1992-08-04 | Arizona Board Of Regents | Laser ablation/ionizaton and mass spectrometric analysis of massive polymers |
| US5650489A (en) | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| TW221493B (en) | 1990-07-10 | 1994-03-01 | Cardiovascular Diagnostics Inc | |
| US5623070A (en) | 1990-07-27 | 1997-04-22 | Isis Pharmaceuticals, Inc. | Heteroatomic oligonucleoside linkages |
| DE4024545A1 (en) | 1990-08-02 | 1992-02-06 | Boehringer Mannheim Gmbh | METHOD AND DEVICE FOR DOSED DELIVERY OF A BIOCHEMICAL ANALYSIS LIQUID TO A TARGET |
| SE9002579D0 (en) | 1990-08-07 | 1990-08-07 | Pharmacia Ab | METHOD AND APPARATUS FOR CARRYING OUT BIOCHEMICAL REACTIONS |
| GB2250858B (en) | 1990-10-22 | 1994-11-30 | Kratos Analytical Ltd | Charged particle extraction arrangement |
| DE4036115C2 (en) | 1990-11-13 | 1997-12-11 | Max Planck Gesellschaft | Method and device for quantitative non-resonant photoionization of neutral particles and use of such a device |
| US5210412A (en) | 1991-01-31 | 1993-05-11 | Wayne State University | Method for analyzing an organic sample |
| WO1992013629A1 (en) | 1991-01-31 | 1992-08-20 | Wayne State University | A method for analyzing an organic sample |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| US5888819A (en) | 1991-03-05 | 1999-03-30 | Molecular Tool, Inc. | Method for determining nucleotide identity through primer extension |
| US5300774A (en) | 1991-04-25 | 1994-04-05 | Applied Biosystems, Inc. | Time-of-flight mass spectrometer with an aperture enabling tradeoff of transmission efficiency and resolution |
| US5175430A (en) | 1991-05-17 | 1992-12-29 | Meridian Instruments, Inc. | Time-compressed chromatography in mass spectrometry |
| US5578444A (en) | 1991-06-27 | 1996-11-26 | Genelabs Technologies, Inc. | Sequence-directed DNA-binding molecules compositions and methods |
| US5726014A (en) | 1991-06-27 | 1998-03-10 | Genelabs Technologies, Inc. | Screening assay for the detection of DNA-binding molecules |
| EP0823486A3 (en) | 1991-06-27 | 2004-02-11 | Genelabs Technologies, Inc. | Method for inhibiting the binding of a dna-binding protein to duplex dna |
| US5853989A (en) | 1991-08-27 | 1998-12-29 | Zeneca Limited | Method of characterisation of genomic DNA |
| US5846717A (en) | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
| GB2260811B (en) | 1991-10-23 | 1995-07-05 | Yorkshire Cancer Research Camp | Detection of malignant tumours |
| US5605662A (en) | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
| IL103674A0 (en) | 1991-11-19 | 1993-04-04 | Houston Advanced Res Center | Method and apparatus for molecule detection |
| ATE241426T1 (en) | 1991-11-22 | 2003-06-15 | Affymetrix Inc A Delaware Corp | METHOD FOR PRODUCING POLYMER ARRAYS |
| US5382793A (en) | 1992-03-06 | 1995-01-17 | Hewlett-Packard Company | Laser desorption ionization mass monitor (LDIM) |
| CH686955A5 (en) | 1992-03-16 | 1996-08-15 | Der Loepfe Ag Geb | Yarn braking device. |
| US5325021A (en) | 1992-04-09 | 1994-06-28 | Clemson University | Radio-frequency powered glow discharge device and method with high voltage interface |
| JPH05308999A (en) | 1992-05-08 | 1993-11-22 | Sumitomo Metal Ind Ltd | Method for determining hepatitis B virus pre-C mutation |
| US5247175A (en) | 1992-05-27 | 1993-09-21 | Finnigan Corporation | Method and apparatus for the deconvolution of unresolved data |
| US5440119A (en) | 1992-06-02 | 1995-08-08 | Labowsky; Michael J. | Method for eliminating noise and artifact peaks in the deconvolution of multiply charged mass spectra |
| US5710028A (en) | 1992-07-02 | 1998-01-20 | Eyal; Nurit | Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor |
| EP0596205A3 (en) | 1992-11-03 | 1996-02-21 | Hewlett Packard Co | Bench supervisor system. |
| US5503980A (en) | 1992-11-06 | 1996-04-02 | Trustees Of Boston University | Positional sequencing by hybridization |
| DE69304292T2 (en) | 1992-11-17 | 1997-01-02 | Univ New York | Tetracyclines including non-antimicrobial, chemically modified tetracyclines inhibiting excessive collagen cross-linking in diabetes |
| US5436143A (en) | 1992-12-23 | 1995-07-25 | Hyman; Edward D. | Method for enzymatic synthesis of oligonucleotides |
| JPH08509857A (en) | 1993-01-07 | 1996-10-22 | シーケノム・インコーポレーテッド | DNA sequencing method by mass spectrometry |
| US6194144B1 (en) | 1993-01-07 | 2001-02-27 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| WO1994017197A1 (en) | 1993-01-25 | 1994-08-04 | Takeda Chemical Industries, Ltd. | ANTIBODY AGAINST β-AMYLOID OR DERIVATIVE THEREOF AND USE THEREOF |
| DE614989T1 (en) | 1993-02-17 | 1995-09-28 | Morphosys Proteinoptimierung | Method for in vivo selection of ligand binding proteins. |
| GB9304462D0 (en) | 1993-03-04 | 1993-04-21 | Kore Tech Ltd | Mass spectrometer |
| JPH08507926A (en) | 1993-03-19 | 1996-08-27 | シーケノム・インコーポレーテツド | DNA sequencing by mass spectrometry via exonuclease degradation |
| US6074823A (en) | 1993-03-19 | 2000-06-13 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
| FR2703052B1 (en)* | 1993-03-26 | 1995-06-02 | Pasteur Institut | New method of nucleic acid sequencing. |
| US5381008A (en) | 1993-05-11 | 1995-01-10 | Mds Health Group Ltd. | Method of plasma mass analysis with reduced space charge effects |
| JPH08501882A (en) | 1993-07-09 | 1996-02-27 | マイクロスキャン、インコーポレイテッド | Liquid dispensing device and method |
| GB9315847D0 (en) | 1993-07-30 | 1993-09-15 | Isis Innovation | Tag reagent and assay method |
| RU2041263C1 (en) | 1993-08-11 | 1995-08-09 | Геннадий Моисеевич Ершов | Method and apparatus for microdosing and dispensing of aqueous solutions onto carrier |
| US6007987A (en) | 1993-08-23 | 1999-12-28 | The Trustees Of Boston University | Positional sequencing by hybridization |
| JP3620120B2 (en) | 1995-10-27 | 2005-02-16 | 株式会社日立製作所 | Method and apparatus for mass spectrometry of solutions |
| US5439649A (en) | 1993-09-29 | 1995-08-08 | Biogenex Laboratories | Automated staining apparatus |
| WO1995009688A1 (en) | 1993-10-04 | 1995-04-13 | Hewlett-Packard Company | Sample preparation system and method |
| US6017693A (en) | 1994-03-14 | 2000-01-25 | University Of Washington | Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry |
| JP3385707B2 (en) | 1994-03-17 | 2003-03-10 | 株式会社日立製作所 | Mass spectrometer |
| US5976798A (en) | 1994-03-30 | 1999-11-02 | Mitokor | Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5498545A (en) | 1994-07-21 | 1996-03-12 | Vestal; Marvin L. | Mass spectrometer system and method for matrix-assisted laser desorption measurements |
| GB9417211D0 (en) | 1994-08-25 | 1994-10-12 | Solicitor For The Affairs Of H | Nucleotide sequencing method |
| DE4431174A1 (en) | 1994-09-01 | 1996-03-07 | Deutsches Krebsforsch | Detecting tumour specific mRNA by conversion to cDNA and amplification |
| US5985356A (en) | 1994-10-18 | 1999-11-16 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
| US6121048A (en) | 1994-10-18 | 2000-09-19 | Zaffaroni; Alejandro C. | Method of conducting a plurality of reactions |
| US5453613A (en) | 1994-10-21 | 1995-09-26 | Hewlett Packard Company | Mass spectra interpretation system including spectra extraction |
| DE4438630A1 (en) | 1994-10-28 | 1996-05-02 | Katharina Dr Pachmann | Amplification of non-characterised DNA fragments |
| US5512295A (en) | 1994-11-10 | 1996-04-30 | The Board Of Trustees Of The Leland Stanford Junior University | Synthetic liposomes for enhanced uptake and delivery |
| US5688642A (en) | 1994-12-01 | 1997-11-18 | The United States Of America As Represented By The Secretary Of The Navy | Selective attachment of nucleic acid molecules to patterned self-assembled surfaces |
| US5601982A (en) | 1995-02-07 | 1997-02-11 | Sargent; Jeannine P. | Method and apparatus for determining the sequence of polynucleotides |
| US5609907A (en) | 1995-02-09 | 1997-03-11 | The Penn State Research Foundation | Self-assembled metal colloid monolayers |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| EP0856055A1 (en) | 1995-04-11 | 1998-08-05 | Trustees Of Boston University | Streptavidin mutants |
| US5770272A (en) | 1995-04-28 | 1998-06-23 | Massachusetts Institute Of Technology | Matrix-bearing targets for maldi mass spectrometry and methods of production thereof |
| US5869240A (en) | 1995-05-19 | 1999-02-09 | Perseptive Biosystems, Inc. | Methods and apparatus for sequencing polymers with a statistical certainty using mass spectrometry |
| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| US5830655A (en) | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
| GB9510699D0 (en) | 1995-05-26 | 1995-07-19 | Fisons Plc | Apparatus and method for surface analysis |
| US5654150A (en) | 1995-06-07 | 1997-08-05 | President And Fellows Of Harvard College | Method of expression cloning |
| US5589136A (en) | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
| US5872010A (en) | 1995-07-21 | 1999-02-16 | Northeastern University | Microscale fluid handling system |
| US5723320A (en) | 1995-08-29 | 1998-03-03 | Dehlinger; Peter J. | Position-addressable polynucleotide arrays |
| US5759779A (en) | 1995-08-29 | 1998-06-02 | Dehlinger; Peter J. | Polynucleotide-array assay and methods |
| US6146854A (en) | 1995-08-31 | 2000-11-14 | Sequenom, Inc. | Filtration processes, kits and devices for isolating plasmids |
| US5869242A (en) | 1995-09-18 | 1999-02-09 | Myriad Genetics, Inc. | Mass spectrometry to assess DNA sequence polymorphisms |
| US5683881A (en) | 1995-10-20 | 1997-11-04 | Biota Corp. | Method of identifying sequence in a nucleic acid target using interactive sequencing by hybridization |
| US5716825A (en) | 1995-11-01 | 1998-02-10 | Hewlett Packard Company | Integrated nucleic acid analysis system for MALDI-TOF MS |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| US6027890A (en) | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
| US5686656A (en) | 1996-02-27 | 1997-11-11 | Aviv Amirav | Method and device for the introduction of a sample into a gas chromatograph |
| US5580434A (en) | 1996-02-29 | 1996-12-03 | Hewlett-Packard Company | Interface apparatus for capillary electrophoresis to a matrix-assisted-laser-desorption-ionization mass spectrometer |
| CA2248084A1 (en) | 1996-03-04 | 1997-09-12 | Genetrace Systems, Inc. | Methods of screening nucleic acids using mass spectrometry |
| WO1997033550A2 (en) | 1996-03-15 | 1997-09-18 | Start Technology Partnership | Methods and compositions for diagnosis and treatment of pathological conditions related to abnormal dopamine receptor expression |
| DE19617011C2 (en) | 1996-04-27 | 2000-11-02 | Bruker Daltonik Gmbh | Matrix component mixture for matrix-assisted laser desorption and ionization and method for preparing a matrix component mixture |
| DE19618032C2 (en) | 1996-05-04 | 2000-04-13 | Bruker Daltonik Gmbh | Prepared Maldi sample carriers that can be stored |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| US6022688A (en) | 1996-05-13 | 2000-02-08 | Sequenom, Inc. | Method for dissociating biotin complexes |
| US6083762A (en) | 1996-05-31 | 2000-07-04 | Packard Instruments Company | Microvolume liquid handling system |
| FR2749662B1 (en) | 1996-06-11 | 1998-08-28 | Elf Aquitaine | ROBOTIZED LABORATORY OF SAMPLES ANALYSIS |
| AU3651497A (en) | 1996-07-05 | 1998-02-02 | Beckman Coulter, Inc. | Automated sample processing system |
| DE19628178C1 (en) | 1996-07-12 | 1997-09-18 | Bruker Franzen Analytik Gmbh | Loading matrix-assisted laser desorption-ionisation sample plate for mass spectrometric analysis |
| US5743960A (en) | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
| US5789395A (en) | 1996-08-30 | 1998-08-04 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds for inhibition of endogenous nitric oxide production |
| US5885841A (en) | 1996-09-11 | 1999-03-23 | Eli Lilly And Company | System and methods for qualitatively and quantitatively comparing complex admixtures using single ion chromatograms derived from spectroscopic analysis of such admixtures |
| US5965363A (en) | 1996-09-19 | 1999-10-12 | Genetrace Systems Inc. | Methods of preparing nucleic acids for mass spectrometric analysis |
| US5777324A (en) | 1996-09-19 | 1998-07-07 | Sequenom, Inc. | Method and apparatus for maldi analysis |
| US5864137A (en) | 1996-10-01 | 1999-01-26 | Genetrace Systems, Inc. | Mass spectrometer |
| US5885775A (en) | 1996-10-04 | 1999-03-23 | Perseptive Biosystems, Inc. | Methods for determining sequences information in polynucleotides using mass spectrometry |
| US6140053A (en) | 1996-11-06 | 2000-10-31 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
| US6024925A (en) | 1997-01-23 | 2000-02-15 | Sequenom, Inc. | Systems and methods for preparing low volume analyte array elements |
| US5900481A (en) | 1996-11-06 | 1999-05-04 | Sequenom, Inc. | Bead linkers for immobilizing nucleic acids to solid supports |
| US6133436A (en) | 1996-11-06 | 2000-10-17 | Sequenom, Inc. | Beads bound to a solid support and to nucleic acids |
| US5854486A (en) | 1996-12-27 | 1998-12-29 | R. T. Hodgson | Method and apparatus for MALDI mass spectrometry |
| US5812272A (en) | 1997-01-30 | 1998-09-22 | Hewlett-Packard Company | Apparatus and method with tiled light source array for integrated assay sensing |
| US6287844B1 (en) | 1997-02-06 | 2001-09-11 | The Trustees Of Boston University | Compositions and methods for controlling genetically engineered organisms |
| US5888778A (en)* | 1997-06-16 | 1999-03-30 | Exact Laboratories, Inc. | High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers |
| US5975492A (en) | 1997-07-14 | 1999-11-02 | Brenes; Arthur | Bellows driver slot valve |
| US6006171A (en) | 1997-07-28 | 1999-12-21 | Vines; Caroline J. | Dynamic maintenance management system |
| US6207370B1 (en) | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
| EP1015632A1 (en)* | 1997-09-15 | 2000-07-05 | Brax Group Limited | Characterising nucleic acid by mass spectrometry |
| US6090558A (en) | 1997-09-19 | 2000-07-18 | Genetrace Systems, Inc. | DNA typing by mass spectrometry with polymorphic DNA repeat markers |
| US5928952A (en) | 1997-11-05 | 1999-07-27 | Zymark Corporation | Scheduled system and method for processing chemical products |
| DE19754978C2 (en) | 1997-12-11 | 2000-07-13 | Bruker Daltonik Gmbh | Sample holder for MALDI mass spectrometry along with the process for producing the plates and applying the samples |
| US6268131B1 (en) | 1997-12-15 | 2001-07-31 | Sequenom, Inc. | Mass spectrometric methods for sequencing nucleic acids |
| DE19803309C1 (en) | 1998-01-29 | 1999-10-07 | Bruker Daltonik Gmbh | Position coordinate determination method for ion peak of mass spectrum |
| US5969350A (en) | 1998-03-17 | 1999-10-19 | Comstock, Inc. | Maldi/LDI time-of-flight mass spectrometer |
| US6284497B1 (en) | 1998-04-09 | 2001-09-04 | Trustees Of Boston University | Nucleic acid arrays and methods of synthesis |
| US6104028A (en) | 1998-05-29 | 2000-08-15 | Genetrace Systems Inc. | Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry |
| US6132685A (en) | 1998-08-10 | 2000-10-17 | Caliper Technologies Corporation | High throughput microfluidic systems and methods |
| US6147344A (en) | 1998-10-15 | 2000-11-14 | Neogenesis, Inc | Method for identifying compounds in a chemical mixture |
| US6270835B1 (en) | 1999-10-07 | 2001-08-07 | Microcoating Technologies, Inc. | Formation of this film capacitors |
| US6225061B1 (en) | 1999-03-10 | 2001-05-01 | Sequenom, Inc. | Systems and methods for performing reactions in an unsealed environment |
| US6232076B1 (en)* | 2000-02-04 | 2001-05-15 | Genaissance Pharmaceuticals, Inc. | Stabilizer of dye sequencing products |