IngThiazide metung yang kataya nung nu iti dati yang magagamit keng metung a tinduk amolecule[1] ampon pinduan adiuretic.[2]
Dening kayanib keng pinduan adiuretic ilapin deng manibatan kengbenzothiadiazine. Kalasag nala dengNa+/Cl- paramasipsip pasibayu ibat kengdistal convoluted tubule kengbatu kapamilatan ning pamanyabat kareng thiazide-mapamakiramdamNa+-Cl- symporter. Deng Thiazides maging lang sangkan keng pangawala ningpotassium ampong pangarakal ningserumuric acid. Ing balangkas pangchemica ning minunang thiazide diuretics atin yang palsingsing ing thiazide ; ing kataya magagamit ya naman kareng panulung a milulupa bisa na enaman chemically thiazides, kalupa na mo dengchlortalidone ampongmetolazone, maigpit deni mayayaus lang balumu thiazide-a diuretics, dapot keraklan ing thiazide magagamit ya mu agiang makananu.
Moreno, E (2006). Affinity-defining Domains in the Na-Cl Cotransporter. J. Biol. Chem. 281, 17266-17275.
| Antihypertensives (C02) anddiuretics (C03) | |
|---|---|
| Sympatholytic agents (kayabe la rengalpha) | kalibdtan kakayi/antiadrenergics:Clonidine •Guanfacine •Methyldopa •Moxonidine •Rilmenidine •adrenergic uptake panyagka (Rescinnamine,Reserpine) ganglion-sasabat/nicotinic antagonist (Mecamylamine,Trimethaphan) peripherally acting/antiadrenergics (Prazosin,Guanethidine,Indoramin,Doxazosin) |
| Vasodilators | Diazoxide •Hydralazine •Minoxidil •Nitroprusside •Phentolamine |
| Deng aliwang antihypertensives | serotonin antagonist (Ketanserin) •endothelin receptor antagonist (Bosentan,Ambrisentan,Sitaxsentan) |
| mababang kisaming diuretics | Thiazide (Bendroflumethiazide,Chlorothiazide,Hydrochlorothiazide) •Chlortalidone •Indapamide •Quinethazone •Mersalyl •Metolazone •Theobromine •Cicletanine |
| Matas kisaming diuretics | Loop diuretic (Bumetanide,Furosemide,Torasemide) |
| Potassium-sparing diuretics | ESC blockers (Amiloride,Triamterene) •aldosterone antagonists (Spironolactone,Eplerenone,Potassium canrenoate,Canrenone) |