Perubahan struktur sel melalui nekrosis atauapoptosis.
Nekrosis (daripadaYunani purba: νέκρωσις "kematian, peringkat kematian, pembunuhan" daripada νεκρός "mati") ialah satu bentukkecederaan sel yang menyebabkankematian pramatangsel padatisu hidup melaluiautolisis.[1] Nekrosis disebabkan oleh faktor yang luaran kepada sel atau tisu, seperti jangkitan, toksin, atau trauma yang menyebabkan pencernaan tidak terkawal atur bagi komponen sel. Berlawanan pula,apoptosis ialah sebab teratur cara dan bersasar yang berlaku secara semula jadi bagi kematian sel. Sementara apoptosis kerap menyediakan kesan bermanfaat kepada organisma, nekrosis hampir selalu memudaratkan dan boleh membawa maut.[2]
^Proskuryakov, S. Y. a., Konoplyannikov, A. G. & Gabai, V. L. Necrosis: a specific form of programmed cell death? Experimental Cell Research 283, 1-16, doi:10.1016/s0014-4827(02)00027-7 (2003).
^Kasper D.L., Zaleznik D.F. (2001). Gas gangrene, antibiotic associated colitis, and other Clostridial infections. In Braunwald E., Kasper D.L. et.al (Eds). Harrisons’s principles of internal McGraw Hill, New York
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2.Kasper D.L., Zaleznik D.F. (2001). Gas gangrene, antibiotic associated colitis, and other Clostridial infections. In Braunwald E., Kasper D.L. et al. (Eds). Harrisons’s principles of internal medicine 15th ed., pp. 922–927. McGraw Hill, New York
3.Vinay K, Abul K. A., Nelson F, Jon A. (2010) Robbins & Cotran Pathologic Basis of Disease, 8th ed., pp. 12–41. Saunders Elsevier, Philadelphia
4.Craft, J. et al. Understanding Pathophysiology. 1 edn, (Mosby Elsevier, 2011).
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10.Proskuryakov, S. Y. a., Konoplyannikov, A. G. & Gabai, V. L. Necrosis: a specific form of programmed cell death? Experimental Cell Research 283, 1-16, doi:10.1016/s0014-4827(02)00027-7 (2003).
14.Eum, H.-A., Cha, Y.-N. & Lee, S.-M. Necrosis and apoptosis: Sequence of liver damage following reperfusion after 60 min ischemia in rats. Biochem. Biophys. Res. Commun. 358, 500-505, doi:10.1016/j.bbrc.2007.04.153 (2007).
15.Cooper, K. L. Skin and Wound Care. Drug Reaction, Skin Care, Skin Loss. Crit. Care Nurse 32, 52-59, doi:10.4037/ccn2012340 (2012).
16.Chotenimitkhun, R. & Rojnuckarin, P. Systemic antivenom and skin necrosis after green pit viper bites. Clinical Toxicology (15563650) 46, 122-125, doi:10.1080/15563650701266826 (2008).
17.Edinger, A. L. & Thompson, C. B. Death by design: apoptosis, necrosis and autophagy. Curr. Opin. Cell Biol. 16, 663-669, doi:10.1016/j.ceb.2004.09.011 (2004).
18.Anu, S., Ernane, D. R. & Morris, D. K. Options for nonsurgical debridment of necrotic wounds. Advances in Skin & Wound Care 14, 96-96 (2001).
19.Horobin, A. J., Shakesheff, K. M. & Pritchard, D. I. Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon the migration of human dermal fibroblasts over a fibronectin-coated surface. Wound Repair. Regen. 13, 422-433, doi:10.1111/j.1067-1927.2005.130410.x (2005).
