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Sentience, also known assapience, was a level of self-awareness equal or greater than that of ahuman.
In2273, whenLeonard McCoy argued in favor of siding with theOrgs against theMachs, whom he saw as just machines,James T. Kirk pointed out that the Machs were sentient beings. (TOScomic: "The Expansionist Syndrome")
In2368, the personnel ofDaystrom One feared that theirartificial intelligence might have become sentient. (TNG -Intelligence Gatheringcomic: "Valued Intelligence")