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| Clinical data | |
|---|---|
| Trade names | Capitrol |
| Other names | cloroxinum, kloroxin, chlorquinol, dichlorchinolinolum, halquinol(s) |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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| CAS Number | |
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| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.011.144 |
| Chemical and physical data | |
| Formula | C9H5Cl2NO |
| Molar mass | 214.05 g·mol−1 |
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Chloroxine (trade nameCapitrol;Kloroxin,Dichlorchinolinol,chlorquinol,halquinol(s));[citation needed] Latincloroxinum, dichlorchinolinolum) is anantibacterialdrug.[1] Oral formulations (under trade name such as Endiaron[2]) are used in infectious diarrhea, disorders of the intestinal microflora (e.g. after antibiotic treatment),giardiasis,inflammatory bowel disease. It is also useful fordandruff andseborrheic dermatitis.,[3] as used in shampoos (Capitrol) and dermal creams like (Valpeda, Triaderm).
Chloroxine has bacteriostatic, fungistatic, and antiprotozoal properties. It is effective againstStreptococci,Staphylococci,Candida,Candida albicans,Shigella, andTrichomonads.[citation needed]
Rarely occurs, but may cause nausea and vomiting associated with oral administration. It may also cause skin irritation.[citation needed]
The FDA lists chloroxine in Pregnancy Category C (risk cannot be ruled out) because no pregnancy studies on the medication have been performed with animals or humans. For this reason, use of chloroxine oral or topical during pregnancy or when breast-feeding is not recommended.[4]
Chloroxine was first prepared in 1888 by A. Hebebrand.[citation needed]
