CAR-226,086
From WikiProjectMed
Jump to navigationJump to search
Chemical compound
Pharmaceutical compound
 | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| PubChemCID | |
| ChemSpider |
|
| CompTox Dashboard(EPA) | |
| Chemical and physical data | |
| Formula | C21H29NO3 |
| Molar mass | 343.467 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
 N Y (what is this?) (verify) | |
CAR-226,086 is a potentanticholinergicdeliriant drug with a fairly long duration of action, related to thechemical warfare agent3-quinuclidinyl benzilate (QNB). It was developed under contract toEdgewood Arsenal during the 1960s as part of theUS military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.
CAR-226,086 was relatively poorly researched compared to other compounds in the series, but notably was found to have the highest central to peripheral effects ratio out of all compounds tested, even higher than that of other CNS-selective agents such asEA-3443.[1][2]
See also
References
- ^Commission on Life Sciences (1982).Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents. Vol. 1. The National Academies Press. pp. 196–199.doi:10.17226/740.ISBN 978-0-309-07759-0.PMID 25032448.
- ^Ketchum JS (2006).Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc.ISBN 978-1-4243-0080-8.
 | Thishallucinogen-related article is astub. You can help Wikipedia byexpanding it. |
Retrieved from "https://mdwiki.org/wiki/CAR-226,086"
Categories:
- Articles with short description
- Short description matches Wikidata
- Short description is different from Wikidata
- Articles with changed ChemSpider identifier
- Articles with changed InChI identifier
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without UNII source
- Drugs missing an ATC code
- Drugs with no legal status
- Drugboxes which contain changes to verified fields
- Drugboxes which contain changes to watched fields
- Centrally selective drugs
- Deliriants
- Incapacitating agents
- Muscarinic antagonists
- Phenylcyclopentylglycolate esters
- Tropanes
- All stub articles
- Hallucinogen stubs