• Bouvier F, Rahier A, Camara B (2005) Biogenesis, molecular regulation and function of plant isoprenoids. Prog Lipid Res 6:357–429

  Article  Google Scholar 

• Cabrita MT, Vale C, Rauter AP (2010) Halogenated compounds from marine algae. Mar Drugs 8:2301–2317

  Article CAS PubMed Central PubMed  Google Scholar 

• Carter GT, Rinehart KL (1978) Brominated indoles fromLaurencia brongniartii. Tetrahedron Lett 19:4479–4482

  Article  Google Scholar 

• Carter-Franklin JN, Butler A (2004) Vanadium bromoperoxidase-catalyzed biosynthesis of halogenated marine natural products. J Am Chem Soc 126:15060–15066

  Article CAS PubMed  Google Scholar 

• Francisco MEY, Turnbull MM, Erikson KL (1998) Cartilagineol, the fourth lineage ofLaurencia-derived polyhalogenated chamigrane. Tetrahedron Lett 39:5289–5292

  Article CAS  Google Scholar 

• Gonzalez AG, Martin JD, Martin VS, Norte M, Perez R, Ruano JZ (1982) Non-terpenoid C-15 metabolites from the red seaweedLaurencia pinnatifida. Tetrahedron 38:1009–1014

  Article CAS  Google Scholar 

• Guella G, Chiasera G, Pietra F (1992) Conformational studies of marine polyhalogenated α-chamigranes using temperature-dependent NMR spectra. Helvet Chem Acta 75:2026–2041

  Article CAS  Google Scholar 

• Ioannou E, Nappo M, Avila C, Vagias C, Roussis V (2009) Metabolites fromAplysia fasciata. J Nat Prod 72:1716–1719

  Article CAS PubMed  Google Scholar 

• Izac RR, Poet SE, Fenical W (1982) The structure of pacifigorgiol, an ichthyotoxic sesquiterpenoid form the Pacific gorgonian coralPacifigorgia cf.adamsii. Tetrahedron Lett 23:3743–3746

  Article CAS  Google Scholar 

• Kamada T (2013)Laurencia chemistry : Structural diversity, chemotaxonomy and bioactive properties of halogenated metabolites. Doctor of Philosophy thesis. Universiti Malaysia Sabah. pp 301

• Kamada T, Vairappan CS (2012) A new bromoallene-producing chemical type of the red algaLaurencia nangii Masuda. Molecules 17:2119–2125

  Article CAS PubMed  Google Scholar 

• Manzo E, Ciavatta ML, Gavagnin M, Puliti R, Mollo E, Guo Y-W, Mattia CA, Mazzarella L, Cimino G (2005) Structure and absolute stereochemistry of novel C₁₅-halogenated acetogenins from the anaspidean molluscAplysia dactylomela. Tetrahedron 61:7456–7460

  Article CAS  Google Scholar 

• Mao S-C, Guo Y-W (2006) A laurane sesquiterpene and rearranged derivatives from the Chinese red algaeLaurencia okamurai Yamada. J Nat Prod 69:1209–1211

  Article CAS PubMed  Google Scholar 

• McPhail KL, Davies-Coleman MT, Copley RCB, Eggleston D (1999) New halogenated sesquiterpenes from South African specimen of the circumtropical sea hareAplysia dactylomela. J Nat Prod 62:1618–1623

  Article CAS  Google Scholar 

• Paul VJ, Fenical W (1980) Palisadins A, B and related monocyclofarsenol-derived sesquiterpenenoids from red marine algaeLaurencia cf.palisada. Tetrahedron Lett 21:2787–2790

  Article CAS  Google Scholar 

• Suzuki M, Kurosawa E (1978) Two new halogenated sesquiterpenes from the red algaLaurencia majuscula Harvey. Tetrahedron Lett 19:4805–4808

  Article  Google Scholar 

• Suzuki M, Vairappan CS (2005) Halogenated secondary metabolites from Japanese species of the red algal genusLaurencia (Rhodomelaceae, Ceramiales). Curr Top Phytochem 7:1–34

  CAS  Google Scholar 

• Vairappan CS, Lee TK (2005) Halogenated secondary metabolites from the sea hareAplysia dactylomela. Malays J Sci 24:17–22

  CAS  Google Scholar 

• Vairappan CS, Daitoh M, Suzuki M, Abe T, Masuda M (2001a) Antibacterial halogenated metabolites from the MalaysianLaurencia species. Phytochemistry 58:291–297

  Article CAS PubMed  Google Scholar 

• Vairappan CS, Suzuki M, Abe T, Masuda M (2001b) Halogenated metabolites with antibacterial activity from the OkinawanLaurencia species. Phytochemistry 58:517–523

  Article CAS PubMed  Google Scholar 

• Vairappan CS, Kawamoto T, Miwa H, Suzuki M (2004) Potent antibacterial activity of halogenated compounds against antibiotic resistant bacteria. Planta Med 70:1087–1090

  Article CAS PubMed  Google Scholar 

• Vairappan CS, Anangdan SP, Lee TK (2007) Additional halogenated secondary metabolites from the sea hareAplysia dactylomela. Malays J Sci 26:57–64

  CAS  Google Scholar 

• Vairappan CS, Suzuki M, Ishii T (2008) Antibacterial activity of halogenated sesquiterpenes from MalaysianLaurencia spp. Phytochemistry 69:2490–2494

  Article CAS PubMed  Google Scholar 

• Vairappan CS, Ishii T, Lee TK, Suzuki M, Zhaoqi Z (2010) Antibacterial activities of a new brominated diterpene from BorneonLaurencia spp. Mar Drugs 8:1743–1749

  Article CAS PubMed Central PubMed  Google Scholar 

• Vairappan CS, Kamada T, Lee WW, Kim EA, Jeon YJ (2013) Anti-inflammatory activity of halogenated secondary metabolites from red algae,Laurencia snackeyi in LPS-stimulated RAW 264.7 macrophages. J Appl Phycol. doi:10.1007/s1081101300236

  Google Scholar 

• Wright AD, Konig GM, Sticher O (1991) New sesquiterpenes and C₁₅ acetogenins from the marine red algaLaurencia implicata. J Nat Prod 54:1025–1033

  Article CAS  Google Scholar 

Download references