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A Monte Carlo-type simulation of the evolution of a multigene family was performed. The model was designed to study the selective forces which may control the size of a multigene family. As expected, we find that direct selection on the size of the multigene family can control its size. More important, we find that selection acting upon the family as a single functional unit, in conjunction with homologous but unequal crossing over, can also control the size of a multigene family.
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Mathematics Department, Cal Poly State University, 93407, San Luis Obispo, CA, USA
J. M. Hood
Division of Biology, California Institute of Technology, 91125, Pasadena, CA, USA
H. V. Huang & L. Hood
- J. M. Hood
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Hood, J.M., Huang, H.V. & Hood, L. A computer simulation of evolutionary forces controlling the size of a multigene family.J Mol Evol15, 181–196 (1980). https://doi.org/10.1007/BF01732947
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