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Abstract
To review steps in evaluation of a newly discovered thyroid nodule, ultrasound characteristics and indications for fine needle aspiration, to understand cytology results and role of molecular analysis and to discuss management options and long-term follow-up based on nodule characteristics and cytology.
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References
Mazzaferri EL. Management of a solitary thyroid nodule. N Engl J Med. 1993;328(8):553–9.
Dean DS, Gharib H. Epidemiology of thyroid nodules. Best Pract Res Clin Endocrinol Metab. 2008;22(6):901–11.
Marqusee E, et al. Usefulness of ultrasonography in the management of nodular thyroid disease. Ann Intern Med. 2000;133(9):696–700.
Chen AY, Jemal A, Ward EM. Increasing incidence of differentiated thyroid cancer in the United States, 1988–2005. Cancer. 2009;115(16):3801–7.
Sipos JA. Advances in ultrasound for the diagnosis and management of thyroid cancer. Thyroid. 2009;19(12):1363–72.
Cooper DS, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2009;19(11):1167–214.
Frates MC, et al. Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. Ultrasound Q. 2006;22(4):231–8. discussion 239–40.
Moon WJ, et al. Benign and malignant thyroid nodules: US differentiation–multicenter retrospective study. Radiology. 2008;247(3):762–70.
Kamran SC, et al. Thyroid nodule size and prediction of cancer. J Clin Endocrinol Metab. 2013;98(2):564–70.
Butros R, et al. Management of infracentimetric thyroid nodules with respect to ultrasonographic features. Eur Radiol. 2007;17(5):1358–64.
Cerbone G, et al. Power Doppler improves the diagnostic accuracy of color Doppler ultrasonography in cold thyroid nodules: follow-up results. Horm Res. 1999;52(1):19–24.
Bonavita JA, et al. Pattern recognition of benign nodules at ultrasound of the thyroid: which nodules can be left alone? AJR Am J Roentgenol. 2009;193(1):207–13.
Kim BM, et al. Sonographic differentiation of thyroid nodules with eggshell calcifications. J Ultrasound Med. 2008;27(10):1425–30.
Papini E, et al. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab. 2002;87(5):1941–6.
Frates MC, et al. Can color Doppler sonography aid in the prediction of malignancy of thyroid nodules? J Ultrasound Med. 2003;22(2):127–31. quiz 132–4.
Azizi G, et al. Performance of elastography for the evaluation of thyroid nodules: a prospective study. Thyroid. 2013;23(6):734–40.
Hagag P, Strauss S, Weiss M. Role of ultrasound-guided fine-needle aspiration biopsy in evaluation of nonpalpable thyroid nodules. Thyroid. 1998;8(11):989–95.
Cibas ES, Ali SZ. The Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2009;132(5):658–65.
Alexander EK, et al. Assessment of nondiagnostic ultrasound-guided fine needle aspirations of thyroid nodules. J Clin Endocrinol Metab. 2002;87(11):4924–7.
Samir AE, et al. Ultrasound-guided percutaneous thyroid nodule core biopsy: clinical utility in patients with prior nondiagnostic fine-needle aspirate. Thyroid. 2012;22(5):461–7.
Carpi A, et al. Aspiration needle biopsy refines preoperative diagnosis of thyroid nodules defined at fine needle aspiration as microfollicular nodule. Biomed Pharmacother. 1996;50(8):325–8.
Nikiforov YE, et al. Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples. J Clin Endocrinol Metab. 2011;96(11):3390–7.
Hodak SP, Rosenthal DS, For The American Thyroid Association Clinical Affairs Committee. Information for clinicians: commercially available molecular diagnosis testing in the evaluation of thyroid nodule fine-needle aspiration specimens. Thyroid. 2013;23(2):131–4.
Alexander EK, et al. Preoperative diagnosis of benign thyroid nodules with indeterminate cytology. N Engl J Med. 2012;367(8):705–15.
Bernet V. Approach to the patient with incidental papillary microcarcinoma. J Clin Endocrinol Metab. 2010;95(8):3586–92.
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Authors and Affiliations
Mayo Clinic, Jacksonville, FL, USA
Ana Maria Chindris & Victor Bernet
- Ana Maria Chindris
Search author on:PubMed Google Scholar
- Victor Bernet
Search author on:PubMed Google Scholar
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Editors and Affiliations
Div. Endocrinology, Diabetes & Bone Disease, Mount Sinai School of Medicine Dept. Medicine, New York, New York, USA
Terry F. Davies
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Chindris, A.M., Bernet, V. (2015). Approach to the Patient with an Incidentally Discovered Thyroid Nodule. In: Davies, T. (eds) A Case-Based Guide to Clinical Endocrinology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2059-4_15
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