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Abstract
Pituitary adenomas can cause symptoms by hormonal hypersecretion. Hypersecretion of prolactin (PRL) is responsible for amenorrhea–galactorrhea in women and decreased libido in men, growth hormone (GH) for acromegaly, adrenocorticotropic hormone (ACTH) for Cushing’s disease, and thyroid-stimulating hormone (TSH) for hyperthyroidism. Tumor mass-related effects such as headaches, visual field abnormalities, and depression of hormonal secretion (hypopituitarism) may also be present.
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Further Reading
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Fleseriu M, Biller BM, Findling JW, Molitch ME, Schteingart DE, Gross C. Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing’s syndrome. J Clin Endocrinol Metab. 2012;97:2039–49.
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Authors and Affiliations
Department of Medicine, Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code BTE28, Portland, OR, 97239, USA
Maria Fleseriu M.D., F.A.C.E.
Department of Neurological Surgery, Oregon Health & Science University, 3303 SW Bond Ave, Mail Code CH8N, Portland, OR, 97239, USA
Maria Fleseriu M.D., F.A.C.E.
OHSU Northwest Pituitary Center, 3303 SW Bond Ave, Mail Code CH8N, Portland, OR, 97239, USA
Maria Fleseriu M.D., F.A.C.E.
- Maria Fleseriu M.D., F.A.C.E.
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Correspondence toMaria Fleseriu M.D., F.A.C.E..
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Div. Endocrinology, Diabetes & Bone Disease, Mount Sinai School of Medicine Dept. Medicine, New York, New York, USA
Terry F. Davies
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Fleseriu, M. (2015). Introduction. In: Davies, T. (eds) A Case-Based Guide to Clinical Endocrinology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2059-4_1
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