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Microalgal bioactive metabolites as promising implements in nutraceuticals and pharmaceuticals: inspiring therapy for health benefits

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Phytochemistry Reviews Aims and scope Submit manuscript

Abstract

The rapid increase in global population and shrinkage of agricultural land necessitates the use of cost-effective renewable sources as alternative to excessive resource-demanding agricultural crops. Microalgae seem to be a potential substitute as it rapidly produces large biomass that can serve as a good source of various functional ingredients that are not produced/synthesized inside the human body and high-value nonessential bioactive compounds. Microalgae-derived bioactive metabolites possess various bioactivities including antioxidant, anti-inflammatory, antimicrobial, anti-carcinogenic, anti-hypertensive, anti-lipidemic, and anti-diabetic activities, thereof rapidly elevating their demand as interesting option in pharmaceuticals, nutraceuticals and functional foods industries for developing new products. However, their utilization in these sectors has been limited. This demands more research to explore the functionality of microalgae derived functional ingredients. Therefore, in this review, we intended to furnish up-to-date knowledge on prospects of bioactive metabolites from microalgae, their bioactivities related to health, the process of microalgae cultivation and harvesting, extraction and purification of bioactive metabolites, role as dietary supplements or functional food, their commercial applications in nutritional and pharmaceutical industries and the challenges in this area of research.

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Acknowledgements

Author(s) would like to convey their sincere thanks to Science and Engineering Research Board (SERB), Federation of Indian Chambers of Commerce and Industry (FICCI), India and Mr Pawan Kumar Goel, Chemical Resources (CHERESO), Panchkula, Haryana, India.

Funding

This work has been supported by the SERB, FICCI India and Chemical Resources (CHERESO), Panchkula under Prime Minister Research Fellowship Program.

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Authors and Affiliations

  1. Department of Biochemistry, Punjab Agricultural University, Ludhiana, Punjab, 141004, India

    Manpreet Kaur

  2. Department of Processing and Food Engineering, Punjab Agricultural University, Ludhiana, Punjab, 141004, India

    Surekha Bhatia

  3. Department of Renewable Energy Engineering, Punjab Agricultural University, Ludhiana, Punjab, 141004, India

    Urmila Gupta

  4. Department of Food Science, University of Massachusetts, Amherst, MA, USA

    Eric Decker

  5. Agricultural Research Station, Agricultural University, Ummedganj, Kota, India

    Yamini Tak

  6. Research & Development, Chemical Resources (CHERESO), Panchkula, Haryana, India

    Manoj Bali

  7. Center for Safe and Improved Food & Biorefining and Advanced Materials Research Center, SRUC Barony Campus, Dumfries, Scotland, UK

    Vijai Kumar Gupta

  8. Sam Hiiginbottom University of Agriculture, Technology and Sciences, Prayagraj, Uttar Pradesh, 211007, India

    Rouf Ahmad Dar

  9. Department of Microbiology, Punjab Agricultural University, Ludhiana, Punjab, 141004, India

    Saroj Bala

Authors
  1. Manpreet Kaur
  2. Surekha Bhatia
  3. Urmila Gupta
  4. Eric Decker
  5. Yamini Tak
  6. Manoj Bali
  7. Vijai Kumar Gupta
  8. Rouf Ahmad Dar
  9. Saroj Bala

Corresponding author

Correspondence toManpreet Kaur.

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The author(s) do not have any conflict of interest.

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Kaur, M., Bhatia, S., Gupta, U.et al. Microalgal bioactive metabolites as promising implements in nutraceuticals and pharmaceuticals: inspiring therapy for health benefits.Phytochem Rev22, 903–933 (2023). https://doi.org/10.1007/s11101-022-09848-7

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