Please use this url to cite or link to this publication:http://hdl.handle.net/1854/LU-5684429

MLA

Soenen, Stefaan, et al. “Investigating the Toxic Effects of Iron Oxide Nanoparticles.”Methods in Enzymology, edited by N Duzgunes, vol. 509, Elsevier Academic Press, 2012, pp. 195–224, doi:10.1016/B978-0-12-391858-1.00011-3.

APA

Soenen, S., De Cuyper, M., De Smedt, S., & Braeckmans, K. (2012). Investigating the toxic effects of iron oxide nanoparticles.Methods in Enzymology,509, 195–224. https://doi.org/10.1016/B978-0-12-391858-1.00011-3

Chicago author-date

Soenen, Stefaan, Marcel De Cuyper, Stefaan De Smedt, and Kevin Braeckmans. 2012. “Investigating the Toxic Effects of Iron Oxide Nanoparticles.” Edited by N Duzgunes.Methods in Enzymology 509: 195–224. https://doi.org/10.1016/B978-0-12-391858-1.00011-3.

Chicago author-date (all authors)

Soenen, Stefaan, Marcel De Cuyper, Stefaan De Smedt, and Kevin Braeckmans. 2012. “Investigating the Toxic Effects of Iron Oxide Nanoparticles.” Ed by. N Duzgunes.Methods in Enzymology 509: 195–224. doi:10.1016/B978-0-12-391858-1.00011-3.

Vancouver

1.

Soenen S, De Cuyper M, De Smedt S, Braeckmans K. Investigating the toxic effects of iron oxide nanoparticles. Duzgunes N, editor. Methods in Enzymology. 2012;509:195–224.

IEEE

[1]

S. Soenen, M. De Cuyper, S. De Smedt, and K. Braeckmans, “Investigating the toxic effects of iron oxide nanoparticles,”Methods in Enzymology, vol. 509, pp. 195–224, 2012.

@article{5684429,  abstract     = {{The use of iron oxide nanoparticles (IONPs) in biomedical research is steadily increasing, leading to the rapid development of novel IONP types and an increased exposure of cultured cells to a wide variety of IONPs. Due to the large variation in incubation conditions, IONP characteristics, and cell types studied, it is still unclear whether IONPs are generally safe or should be used with caution. During the past years, several contradictory observations have been reported, which highlight the great need for a more thorough understanding of cell-IONP interactions. To improve our knowledge in this field, there is a great need for standardized protocols and toxicity assays, that would allow to directly compare the cytotoxic potential of any IONP type with previously screened particles. Here, several approaches are described that allow to rapidly but thoroughly address several parameters which are of great impact for IONP-induced toxicity. These assays focus on acute cytotoxicity, induction of reactive oxygen species, measuring the amount of cell-associated iron, assessing cell morphology, cell proliferation, cell functionality, and possible pH-induced or intracellular IONP degradation. Together, these assays may form the basis for any detailed study on IONP cytotoxicity.}},  author       = {{Soenen, Stefaan and De Cuyper, Marcel and De Smedt, Stefaan and Braeckmans, Kevin}},  editor       = {{Duzgunes, N}},  isbn         = {{9780123918581}},  issn         = {{0076-6879}},  journal      = {{Methods in Enzymology}},  keywords     = {{MAGNETIC NANOPARTICLES,TRANSFERRIN RECEPTOR,DRUG-DELIVERY,MAGNETOLIPOSOMES,FERUMOXIDES,CYTOTOXICITY,NANOTOXICITY,TRACKING,MESENCHYMAL STEM-CELLS,PARTICLES}},  language     = {{eng}},  pages        = {{195--224}},  publisher    = {{Elsevier Academic Press}},  title        = {{Investigating the toxic effects of iron oxide nanoparticles}},  url          = {{http://doi.org/10.1016/B978-0-12-391858-1.00011-3}},  volume       = {{509}},  year         = {{2012}},}

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