 Ranitidine | |
|---|---|
group of stereoisomers(en) | |
| Bayanai | |
| Ƙaramin ɓangare na | furans(en) datertiary amine(en) |
| Amfani | essential medicine(en) |
| Sinadaran dabara | C₁₃H₂₂N₄O₃S |
| Canonical SMILES(en) | CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C |
| Active ingredient in(en) | Wal-Zan(en) daZantac(en) |
| Pregnancy category(en) | Australian pregnancy category B1(en) daUS pregnancy category B(en) |
| Subject has role(en) | H2 antagonists(en) daanti-ulcer drug(en) |
| Stylized name(en) | raNITIdine |
Ranitidine, wanda ake sayar da shi a ƙarƙashin sunan kasuwanciZantac da sauransu, magani ne wanda ke rage yawan samar da acid na ciki.[1] An kuma fi amfani da shi don magance cututtukan cututtukan peptic, cututtukan gastroesophageal reflux, da ciwon Zollinger-Ellison.[1] Har ila yau, akwai shaidar ɗan lokaci na fa'ida ga amya.[2] Ana iya ɗauka ta baki, ta hanyar allura a cikin tsoka, ko cikin jijiya.[1]
Abubuwan da aka sani sun haɗa da ciwon kai, da zafi ko ƙonewa idan an yi musu ta hanyar allura.[1] Mummunan illa na iya haɗawa da matsalolin hanta, jinkirin bugun zuciya, ciwon huhu, da kuma yuwuwar rufe kansar ciwon ciki.[1] Hakanan yana da alaƙa da haɓakar haɗarinClostridium difficile colitis.[3] Gabaɗaya yana da lafiya a cikin ciki.[1] Ranitidine antagonist mai karɓar H2 histamine ne wanda kuma ke aiki ta hanyar toshe histamine, don haka yana rage adadin acid ɗin da ƙwayoyin ciki ke fitarwa.[1]
An gano Ranitidine a Ingila, UK a cikin shekarar 1976, kuma ya fara amfani da kasuwanci a 1981.[4] Yana cikin Jerin Mahimman Magunguna na Hukumar Lafiya ta Duniya.[5] Ana samunsa azaman magani na gama-gari.[1] Farashin 2015 a cikin ƙasashe masu tasowa ya kai dalar Amurka 0.01-0.05 kowace kwamfutar hannu.[6] A Amurka kusan $0.05 ne a kowane kashi.[1] A cikin 2017, shi ne na 48th mafi yawan magunguna a Amurka, tare da rubutattun magunguna sama da miliyan 16.[7][8]
A cikin Satumba 2019, an gano carcinogen N-nitrosodimethylamine (NDMA) a cikin samfuran ranitidine daga masana'antun da yawa, wanda ya haifar da tunowa.[9][10][11] A cikin Afrilu 2020, an janye shi daga kasuwar Amurka kuma an dakatar da shi a cikin Tarayyar Turai da Ostiraliya saboda waɗannan damuwa.[12][13][14][15]