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Lymphoma

From Wikipedia
lymphoma
class of disease,signs den symptoms
Subclass ofhematologic cancer,lymphatic system cancer,lymphoma and pseudolymphoma,lymphoid neoplasm,disease Edit
Manner of deathnatural causes Edit
Cause of deathlymphoma Edit
Health specialtyhematology,oncology Edit
Anatomical locationlymph node Edit
Genetic associationHLA-DQB2 Edit
ICD-9-CM202.80,200.1,200.0 Edit
ICPC 2 IDB72 Edit
NCI Thesaurus IDC3208,C7065 Edit

Lymphoma be a group of blood den lymph tumors wey dey develop from lymphocytes (a type of white blood cell).[1] De name typically dey refer to just decancerous versions rada dan all such tumors.[1] Signs den symptoms fi include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, den constantly dey feel tired.[2][3] De enlarged lymph nodes usually be painless.[2] De sweats be most common at night.[2][3]

Chaw subtypes of lymphomas be known.[4] De two main categories of lymphomas be de non-Hodgkin lymphoma (NHL) (90% of cases)[5][6] den Hodgkin lymphoma (HL) (10%).[5] Lymphomas,leukemias den myelomas be a part of de broader group of tumors of de hematopoietic den lymphoid tissues.[7]

Risk factors for Hodgkin lymphoma dey include infection plus Epstein–Barr virus den a history of de disease insyd de family.[2] Risk factors for common types of non-Hodgkin lymphomas dey includeautoimmune diseases,HIV/AIDS, infection plus human T-lymphotropic virus, immunosuppressant medications, den sam pesticides.[3][8] Eating large amounts of red meat den tobacco smoking sanso fi increase de risk.[9][10][11] Diagnosis, if enlarged lymph nodes be present, usually be by lymph node biopsy.[2][3] Blood, urine, den bone marrow testing sanso fi be useful insyd de diagnosis.[3] Dem then fi do medical imaging to determine if den wer na de cancer spread.[2][3] Lymphoma most often dey spread to de lungs, liver, den brain.[2][3]

Treatment fi involve one anaa more of de following: chemotherapy, radiation therapy, proton therapy, targeted therapy, den surgery.[2][3] Insyd sam non-Hodgkin lymphomas, an increased amount of protein wey be produced by de lymphoma cells dey cause de blood make e cam be so thick wey plasmapheresis dey perform to remove de protein.[3] Watchful waiting fi be appropriate for certain types.[3] De outcome dey depend on de subtype, plus sam be curable den treatment prolonging survival insyd chaw.[5] De five-year survival rate insyd deUnited States for all Hodgkin lymphoma subtypes be 85%,[12] while dat for non-Hodgkin lymphomas be 69%.[13] Worldwide, na lymphomas develop insyd 566,000 people insyd 2012 wey e cause 305,000 deaths.[14] Dem dey make up 3–4% of all cancers, wey dey make dem as a group de seventh-most-common form.[14][15] Insyd kiddies, dem be de third-most-common cancer.[16] Dem dey occur more often insyd de developed world dan insyd de developing world.[14]

References

[edit |edit source]
  1. 12Taylor, Elizabeth J. (2000).Dorland's Illustrated medical dictionary (29th ed.). Philadelphia: Saunders. p. 1038.ISBN 0-7216-6254-4.
  2. 12345678"General Information About Adult Hodgkin Lymphoma".National Cancer Institute. 2014-04-23.Archived from the original on 5 July 2014. Retrieved20 June 2014.
  3. 12345678910"General Information About Adult Non-Hodgkin Lymphoma".National Cancer Institute. 2014-04-25.Archived from the original on 5 July 2014. Retrieved20 June 2014.
  4. Aditya Bardia (2010).Johns Hopkins Patients' Guide to Lymphoma. Jones & Bartlett Learning. p. 6.ISBN 978-1-4496-3141-3.Archived from the original on 2017-09-10.
  5. 123"The Lymphoma Guide Information for Patients and Caregivers"(PDF).Leukemia and Lymphoma Society. 2013.Archived(PDF) from the original on 14 July 2014. Retrieved20 June 2014.
  6. "Lymphoma".NCI. 2011-02-02.Archived from the original on 5 July 2014. Retrieved13 June 2014.
  7. Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, et al. (July 2009)."The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes".Blood.114 (5):937–951.doi:10.1182/blood-2009-03-209262.PMID 19357394.S2CID 3101472.
  8. Hu L, Luo D, Zhou T, Tao Y, Feng J, Mei S (December 2017). "The association between non-Hodgkin lymphoma and organophosphate pesticides exposure: A meta-analysis".Environmental Pollution.231 (Pt 1):319–328.Bibcode:2017EPoll.231..319H.doi:10.1016/j.envpol.2017.08.028.PMID 28810201.
  9. Kamper-Jørgensen M, Rostgaard K, Glaser SL, Zahm SH, Cozen W, Smedby KE, et al. (September 2013)."Cigarette smoking and risk of Hodgkin lymphoma and its subtypes: a pooled analysis from the International Lymphoma Epidemiology Consortium (InterLymph)".Annals of Oncology.24 (9):2245–2255.doi:10.1093/annonc/mdt218.PMC 3755332.PMID 23788758.
  10. Yang L, Dong J, Jiang S, Shi W, Xu X, Huang H, et al. (November 2015)."Red and Processed Meat Consumption Increases Risk for Non-Hodgkin Lymphoma: A PRISMA-Compliant Meta-Analysis of Observational Studies".Medicine.94 (45) e1729.doi:10.1097/MD.0000000000001729.PMC 4912242.PMID 26559248.
  11. Solimini AG, Lombardi AM, Palazzo C, De Giusti M (May 2016). "Meat intake and non-Hodgkin lymphoma: a meta-analysis of observational studies".Cancer Causes & Control.27 (5):595–606.doi:10.1007/s10552-016-0745-2.hdl:11573/865541.PMID 27076059.S2CID 17430078.
  12. "Hodgkin Lymphoma—SEER Stat Fact Sheets". Seer.cancer.gov.Archived from the original on 2012-10-17. Retrieved2012-08-26.
  13. "SEER Stat Fact Sheets: Non-Hodgkin Lymphoma".NCI.Archived from the original on 6 July 2014. Retrieved18 June 2014.
  14. 123World Cancer Report 2014. World Health Organization. 2014. pp. Chapter 5.13.ISBN 978-92-832-0429-9.
  15. Marcus, Robert (2013).Lymphoma: pathology, diagnosis and treatment (Second ed.). Cambridge University Press. p. 1.ISBN 978-1-107-01059-8.Archived from the original on 2015-09-06.
  16. Tepper, Joel E.; Kastan, Michael B.; Doroshow, James H.; Armitage, James O.; Niederhuber, John E. (2014). "Childhood lymphoma".Abeloff's clinical oncology (Fifth ed.). Elsevier. p. Chapter 97.ISBN 978-1-4557-2865-7.

External links

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