Utility functions for modelling and simulation workflows within esqLABS organization

• UpdatedMar 17, 2025
• HTML

The physiologically-based whole-body model of the glucose-insulin-glucagon regulatory system

• UpdatedMar 23, 2019
• MATLAB

Implementation of inhalation model in MoBi

• UpdatedApr 14, 2023
• R

Physiologically Based Pharmacokinetic Models for Pregnant Women

• UpdatedAug 20, 2024

Create diagrams with ggplot.

• UpdatedOct 18, 2018
• R

Whole-body PBPK model of digoxin as P-gp DDI victim drug

• UpdatedSep 23, 2024
• R

Open access PBPK modelling platform

• UpdatedOct 15, 2024
• C#

Whole-body PBPK model of Vancomycin

• UpdatedOct 14, 2021
• MATLAB

A Quantitative Systems Pharmacology kidney model of diabetes associated renal hyperfiltration and the effects of SGLT inhibitors.

• UpdatedFeb 27, 2020
• R

• UpdatedJun 21, 2023

Whole-body PBPK model of voriconazole as CYP2C19 substrate and CYP3A4 perpetrator drug

• UpdatedJul 18, 2023

Physiology-based systems pharmacology model of thyroid hormones regulation in rat and human

• UpdatedJan 30, 2023
• R

• UpdatedMay 25, 2023

Code for the paper "A Combination of Machine Learning and PBPK Modeling Approach for Pharmacokinetics Prediction of Small Molecules in Humans"

• UpdatedJan 8, 2024
• Jupyter Notebook

Modeling of published clinical Itraconazole-Digoxin-DDI studies for model evaluation

• UpdatedSep 20, 2024

Whole-body PBPK model of Irinotecan (CPT-11) & SN-38 determining tumor tissue kinetics of both parent drug & active metabolite.

• UpdatedApr 8, 2021

PBPK Modeling For Therapeutic Nanoparticles Loaded With Drug

• UpdatedSep 3, 2024
• Julia

• UpdatedJul 5, 2024

Cabozantinib PBPK

• UpdatedMay 25, 2021

Whole-body PBPK model of midazolam as CYP3A4 DDI victim drug

• UpdatedJul 7, 2022
• MATLAB