Bioinformatics

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Bioinformatics is an interdisciplinary field that intersects with biology, computer science, mathematics and statistics. It concerns itself with the development and use of methods and software tools for collecting and analyzing biological data.

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Developer-Y /cs-video-courses

Star70k

List of Computer Science courses with video lectures.

computer-science security machine-learning bioinformatics web-development reinforcement-learning computer-vision deep-learning algorithms robotics computational-biology databases embedded-systems systems computational-physics quantum-computing computer-architecture database-systems

UpdatedOct 2, 2025

plotly /dash

Sponsor

Star24.1k

Data Apps & Dashboards for Python. No JavaScript Required.

react python productivity flask finance data-science bioinformatics jupyter web-app modeling plotly data-visualization dash rstats gui-framework charting technical-computing plotly-dash

UpdatedOct 7, 2025
Python

biopython /biopython

Star4.8k

Official git repository for Biopython (originally converted from CVS)

python bioinformatics genomics protein-structure dna protein biopython phylogenetics sequence-alignment

UpdatedOct 7, 2025
Python

danielecook /Awesome-Bioinformatics

Sponsor

Star3.7k

A curated list of awesome Bioinformatics libraries and software.

awesome bioinformatics awesome-list

UpdatedMar 21, 2025

seandavi /awesome-single-cell

Star3.5k

Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc.

python bioinformatics analysis clustering gene-expression data-visualization dimensionality-reduction awesome-list data-integration atac-seq single-cell rna-seq-data scrna-seq-data cell-cycle cell-differentiation gene-expression-profiles analysis-pipeline cell-populations rna-seq-experiments cell-clusters

UpdatedAug 26, 2025

google /deepvariant

Star3.5k

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

science machine-learning bioinformatics deep-learning genomics genome tensorflow ngs sequencing dna deep-neural-network deepvariant

UpdatedSep 10, 2025
Python

nextflow-io /nextflow

Star3.2k

A DSL for data-driven computational pipelines

docker groovy hello aws cloud bioinformatics pipeline nextflow hpc reproducible-research workflow-engine slurm pipeline-framework sge singularity reproducible-science dataflow singularity-containers

UpdatedOct 7, 2025
Groovy

sokrypton /ColabFold

Star2.5k

Making Protein folding accessible to all!

bioinformatics protein-structure structure-prediction multiple-sequence-alignment

UpdatedSep 18, 2025
Jupyter Notebook

scverse /scanpy

Star2.2k

Single-cell analysis in Python. Scales to >100M cells.

python data-science machine-learning bioinformatics transcriptomics visualize-data scanpy anndata scverse

UpdatedOct 6, 2025
Python

OpenGene /fastp

Star2.2k

An ultra-fast all-in-one FASTQ preprocessor (QC/adapters/trimming/filtering/splitting/merging...)

adapter quality bioinformatics quality-control filter ngs sequencing overlap splitting duplication umi trimming preprocessing filtering illumina fastq merging qc polyg

UpdatedSep 11, 2025
C++

lh3 /minimap2

Star2k

A versatile pairwise aligner for genomic and spliced nucleotide sequences

bioinformatics genomics sequence-alignment spliced-alignment

UpdatedOct 5, 2025
C

allenai /scispacy

Star1.9k

A full spaCy pipeline and models for scientific/biomedical documents.

nlp bioinformatics spacy biomedical custom-pipes scientific-documents

UpdatedOct 1, 2025
Python

broadinstitute /gatk

Star1.9k

Official code repository for GATK versions 4 and up

science bioinformatics spark genomics genome ngs sequencing dna gatk

UpdatedOct 7, 2025
Java

soedinglab /MMseqs2

Star1.8k

MMseqs2: ultra fast and sensitive search and clustering suite

bioinformatics taxonomy metagenomics alignment sequence-clustering profile-search sequence-search linclust mmseqs blast

UpdatedSep 25, 2025
C

bioconda /bioconda-recipes

Star1.8k

Conda recipes for the bioconda channel.

bioinformatics conda hacktoberfest package-management

UpdatedOct 7, 2025
Shell

lh3 /bwa

Star1.7k

Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment)

bioinformatics genomics sequence-alignment fm-index

UpdatedMar 22, 2025
C

galaxyproject /galaxy

Star1.6k

Data intensive science for everyone.

science workflow bioinformatics pipeline genomics workflow-engine ngs sequencing dna usegalaxy hacktoberfest

UpdatedOct 7, 2025
Python

lh3 /seqtk

Star1.5k

Toolkit for processing sequences in FASTA/Q formats

bioinformatics sequence-analysis

UpdatedJun 1, 2025
C

shenwei356 /seqkit

Star1.5k

A cross-platform and ultrafast toolkit for FASTA/Q file manipulation

golang bioinformatics cross-platform tool toolkit fasta manipulation sequence fastq

UpdatedOct 7, 2025
Go

MultiQC /MultiQC

Star1.4k

Aggregate results from bioinformatics analyses across many samples into a single report.

python bioinformatics quality-control analysis reporting pypi data-visualization bioconda multiqc vizualisation seqera

UpdatedSep 17, 2025
JavaScript

Followers: 1.8k followers
Website: github.com/topics/bioinformatics
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