The function this is failing in ishttps://github.com/pythonnet/clr-loader/blob/master/clr_loader/__init__.py#L89

Is this really the only output you are seeing? There should at least be an exception message after this...

I have the similar issue on two Windows 11 machines (In my case it's .net8 solution but requested by pythonnet is .net9):
'python.exe' (Win32): Loaded 'C:\Python311\python.exe'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\ntdll.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\kernel32.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\KernelBase.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\ucrtbase.dll'.
'python.exe' (Win32): Loaded 'C:\Python311\vcruntime140.dll'.
'python.exe' (Win32): Loaded 'C:\Python311\python311.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\ws2_32.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\version.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\rpcrt4.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\msvcrt.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\bcrypt.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\advapi32.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\sechost.dll'.
'python.exe' (Win32): Loaded 'C:\Program Files\Avecto\Privilege Guard Client\PGHook.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\bcryptprimitives.dll'.
'python.exe' (Win32): Loaded 'C:\Python311\python3.dll'.
'python.exe' (Win32): Loaded 'C:\Python311\DLLs_bz2.pyd'.
'python.exe' (Win32): Loaded 'C:\Python311\DLLs_lzma.pyd'.
'python.exe' (Win32): Loaded 'C:\Python311\Lib\site-packages_cffi_backend.cp311-win_amd64.pyd'. Module was built without symbols.
'python.exe' (Win32): Loaded 'C:\Windows\System32\user32.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\win32u.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\gdi32.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\gdi32full.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\msvcp_win.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\imm32.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\psapi.dll'.
'python.exe' (Win32): Loaded 'C:\Windows\System32\kernel.appcore.dll'.
'python.exe' (Win32): Loaded 'C:\Program Files\dotnet\host\fxr\8.0.8\hostfxr.dll'.
You must install or update .NET to run this application.

App: C:\Python311\python.exe
Architecture: x64Framework: 'Microsoft.NETCore.App', version '9.0.0' (x64).NET location: C:\Program Files\dotnet
The following frameworks were found: 3.1.24 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 5.0.17 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 6.0.9 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 6.0.33 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 7.0.5 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 7.0.20 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 8.0.7 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 8.0.8 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 9.0.0-preview.7.24405.7 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App] 9.0.0-rc.1.24431.7 at [C:\Program Files\dotnet\shared\Microsoft.NETCore.App]
Learn more:
https://aka.ms/dotnet/app-launch-failed

To install missing framework, download:
https://aka.ms/dotnet-core-applaunch?framework=Microsoft.NETCore.App&framework_version=9.0.0&arch=x64&rid=win-x64&os=win10'python.exe' (Win32): Unloaded 'C:\Program Files\dotnet\host\fxr\8.0.8\hostfxr.dll'

Please do not use the load("coreclr") and try:
from clr_loader import get_coreclr
from pythonnet import set_runtime

rt = get_coreclr(runtime_config="runtimeconfig.json")
set_runtime(rt)

In the runtimeconfig.json replace with your framework
{
"runtimeOptions": {
"tfm": "net8.0",
"framework":
{
"name": "Microsoft.NETCore.App",
"version": "8.0.8"
}
}
}