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Exploratory Web Apps for Analyzing Clinical Trial Data
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insightsengineering/teal
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teal is ashiny-based interactive exploration framework for analyzing data.teal applications require app developers to specify:
- Data, which can be:
- CDISC data, commonly used for clinical trial reporting
- Independent datasets, for example from a
data.frame - Related datasets, for example a set of
data.frameswith key columns to enable data joins MultiAssayExperimentobjects which areRdata structures for representing and analyzing multi-omics experiments
tealmodules:teal modulesareshinymodules built within thetealframework that specify analysis to be performed. For example, it can be a module for exploring outliers in the data, or a module for visualizing the data in line plots. Although these can be created from scratch, manytealmodules have been released and we recommend starting with modules found in the following packages:teal.modules.general: general modules for exploring relational/independent/CDISC datateal.modules.clinical: modules specific to CDISC data and clinical trial reportingteal.modules.hermes: modules for analyzingMultiAssayExperimentobjects
A lot of the functionality of theteal framework derives from the following packages:
teal.logger: standardizes logging withintealframework.teal.code: handles reproducibility of outputs.teal.data: creating and loading the data needed fortealapplications.teal.widgets:shinycomponents used withinteal.teal.slice: provides a filtering panel to allow filtering of data.teal.reporter: allowstealapplications to generate reports.teal.transform: allows the creation of reproducible transform and merge module for teal applications.
Dive deeper intoteal with our comprehensive video guide.Please click the image below to start learning:
install.packages("teal")Alternatively, you might also use the development version.
# install.packages("pak")pak::pak("insightsengineering/teal")
library(teal)app<- init(data= teal_data(iris=iris),modules=list( module(label="iris histogram",server=function(input,output,session,data) { updateSelectInput(session=session,inputId="var",choices= names(data()[["iris"]])[1:4])output$hist<- renderPlot({ req(input$var) hist(x= data()[["iris"]][[input$var]]) }) },ui=function(id) {ns<- NS(id)list( selectInput(inputId= ns("var"),label="Column name",choices=NULL), plotOutput(outputId= ns("hist")) ) } ) ))shinyApp(app$ui,app$server)
Please seeteal.gallery andTLG Catalog to see examples ofteal apps.
Please start with the"Technical Blueprint" article,"Getting Started" article, and then otherpackage vignettes for more detailed guide.
If you encounter a bug or have a feature request, please file an issue. For questions, discussions, and updates, use theteal channel in thepharmaverse slack workspace.
This package is a result of a joint efforts by many developers and stakeholders. We would like to thank everyone who contributed so far!
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Exploratory Web Apps for Analyzing Clinical Trial Data
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