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Modeling heme pathogenicity and pathway dysregulation in the context of hemolytic disorders
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hemekg/hemekg
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Assembling and modeling the knowledge around heme pathogenicity and pathway dysregulation in the context of hemolyticdisorders. The data hosted in this repo was curated byFarah Humayun in context of herMaster's Thesis. The curated documents are located in thehemekg
directory.
If you find HemeKG useful in your work, please consider citing:
[1] | Humayun, F.,et al. (2020).A computational approach for mapping heme biology in the context of hemolyticdisorders.Front. Bioeng. Biotechnol. 8:74. |
Thehemekg
python package can be installed fromPyPIwith the following code in your shell:
$ pip install hemekg
The development version can be installed fromGitHubwith:
$ git clone https://github.com/hemekg/hemekg.git$cd hemekg$ pip install -e.
To see all the commands, simply run:
$ hemekg
To get the BEL graph, use the following code:
>>>importhemekg>>>graph=hemekg.get_graph()>>>graph.summarize()
Auxiliary annotations are located in the hemekg/annotations directory.These include:
- TimePoint.
- Species.
- Concentration.
SeeA Listing of Publicly Available Content in the Biological Expression Language (BEL) on Charles Tapley Hoyt's blogfor more BEL content.
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Modeling heme pathogenicity and pathway dysregulation in the context of hemolytic disorders