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Draft data model for GO-CAMs

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geneontology/gocam-py

GO CAM Data Model (Python)

Website

https://geneontology.github.io/gocam-py

About

Example yaml/json

id:gomodel:568b0f9600000284title:Antibacterial innate immune response in the intestine via MAPK cascade (C.elegans)taxon:NCBITaxon:6239status:productioncomments:-'Automated change 2023-03-16: RO:0002212 replaced by RO:0002630'-'Automated change 2023-03-16: RO:0002213 replaced by RO:0002629'activities:-id:gomodel:568b0f9600000284/57ec3a7e00000079enabled_by:WB:WBGene00006575molecular_function:evidence:    -term:ECO:0000314reference:PMID:15625192provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2019-09-23'provenances:[]term:GO:0035591occurs_in:evidence:    -term:ECO:0000314reference:PMID:15625192provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-06-28'term:GO:0005737part_of:evidence:    -term:ECO:0000315reference:PMID:19837372with_objects:      -WB:WBVar00241222|WB:WBVar00241223provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2021-07-08'term:GO:0140367causal_associations:  -evidence:    -term:ECO:0000315reference:PMID:15123841provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-05-31'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/57ec3a7e00000109-id:gomodel:568b0f9600000284/580685bd00000135enabled_by:WB:WBGene00011979molecular_function:evidence:    -term:ECO:0000307reference:GO_REF:0000015provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-11-12'provenances:[]term:GO:0003674occurs_in:evidence:    -term:ECO:0000307reference:GO_REF:0000015provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2021-11-29'term:GO:0110165part_of:evidence:    -term:ECO:0000270reference:PMID:17096597provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2021-07-08'term:GO:0140367-id:gomodel:568b0f9600000284/5745387b00000588enabled_by:WB:WBGene00012019molecular_function:evidence:    -term:ECO:0000314reference:PMID:17728253provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2019-09-23'provenances:[]term:GO:0004674occurs_in:evidence:    -term:ECO:0000314reference:PMID:17728253provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-07-01'term:GO:0009898part_of:evidence:    -term:ECO:0000315reference:PMID:19371715provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2016-10-19'term:GO:0140367causal_associations:  -evidence:    -term:ECO:0000315reference:PMID:19371715provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-07-02'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/568b0f9600000285-id:gomodel:568b0f9600000284/5b528b1100002286enabled_by:WB:WBGene00006599molecular_function:evidence:    -term:ECO:0000501reference:GO_REF:0000037with_objects:      -UniProtKB-KW:KW-0723provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-09-06'    -term:ECO:0000315reference:PMID:23072806provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-09-06'    -term:ECO:0000501reference:GO_REF:0000002with_objects:      -InterPro:IPR000961provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-09-06'    -term:ECO:0000318reference:PAINT_REF:24356with_objects:      -PANTHER:PTN000683254provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-09-06'provenances:[]term:GO:0004674part_of:evidence:    -term:ECO:0000315reference:PMID:22470487provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-09-06'term:GO:0002225causal_associations:  -evidence:    -term:ECO:0000316reference:PMID:19371715provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-07-01'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/5745387b00000588-id:gomodel:568b0f9600000284/57ec3a7e00000119enabled_by:WB:WBGene00004758molecular_function:evidence:    -term:ECO:0000314reference:PMID:11751572provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2019-09-23'provenances:[]term:GO:0004708occurs_in:evidence:    -term:ECO:0000318reference:PMID:21873635provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-06-28'term:GO:0005737part_of:evidence:    -term:ECO:0000315reference:PMID:12142542provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2020-10-28'term:GO:0140367causal_associations:  -evidence:    -term:ECO:0000315reference:PMID:12142542provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-05-31'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/568b0f9600000285-id:gomodel:568b0f9600000284/568b0f9600000285enabled_by:WB:WBGene00004055molecular_function:evidence:    -term:ECO:0000314reference:PMID:20369020provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2020-10-28'provenances:[]term:GO:0004707occurs_in:evidence:    -term:ECO:0000314reference:PMID:20133945provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-07-01'term:GO:0005829part_of:evidence:    -term:ECO:0000315reference:PMID:12142542provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2020-10-28'term:GO:0140367causal_associations:  -evidence:    -term:ECO:0000314reference:PMID:20369020provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-05-31'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/568b0f9600000287-id:gomodel:568b0f9600000284/57ec3a7e00000109enabled_by:WB:WBGene00003822molecular_function:evidence:    -term:ECO:0000314reference:PMID:11751572provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2019-09-23'provenances:[]term:GO:0004709occurs_in:evidence:    -term:ECO:0000314reference:PMID:15625192provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-06-28'term:GO:0005737part_of:evidence:    -term:ECO:0000315reference:PMID:12142542provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2020-10-28'term:GO:0140367causal_associations:  -evidence:    -term:ECO:0000315reference:PMID:12142542provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-05-31'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/57ec3a7e00000119-id:gomodel:568b0f9600000284/5b91dbd100000652enabled_by:WB:WBGene00006923molecular_function:evidence:    -term:ECO:0000314reference:PMID:15116070provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'provenances:[]term:GO:0017017occurs_in:evidence:    -term:ECO:0000250reference:PMID:15116070with_objects:      -UniProt:Q920R2provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-07-01'term:GO:0005737part_of:evidence:    -term:ECO:0000316reference:PMID:22554143with_objects:      -WB:WBGene00002187provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'    -term:ECO:0000315reference:PMID:22554143provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'term:GO:1900425causal_associations:  -evidence:    -term:ECO:0000315reference:PMID:22554143provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-09'predicate:RO:0002630downstream_activity:gomodel:568b0f9600000284/5b91dbd100000659  -evidence:    -term:ECO:0000315reference:PMID:15256594provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-06-20'    -term:ECO:0000315reference:PMID:22554143provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2020-10-28'predicate:RO:0002630downstream_activity:gomodel:568b0f9600000284/568b0f9600000285-id:gomodel:568b0f9600000284/5b91dbd100000659enabled_by:WB:WBGene00002187molecular_function:evidence:    -term:ECO:0000353reference:PMID:12435362with_objects:      -WB:WBGene00001599provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'    -term:ECO:0000353reference:PMID:12435362with_objects:      -WB:WBGene00001600provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'    -term:ECO:0000353reference:PMID:23437011with_objects:      -WB:WBGene00001345provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'    -term:ECO:0000353reference:PMID:23437011with_objects:      -WB:WBGene00001345provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'provenances:[]term:GO:0005515occurs_in:evidence:    -term:ECO:0000314reference:PMID:17699606provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2019-07-01'term:GO:0005737part_of:evidence:    -term:ECO:0000315reference:PMID:22554143with_objects:      -WB:WBGene00002187provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-08'term:GO:1900181-id:gomodel:568b0f9600000284/568b0f9600000287enabled_by:WB:WBGene00000223molecular_function:evidence:    -term:ECO:0000250reference:PMID:20369020provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-29'provenances:[]term:GO:0000981occurs_in:evidence:    -term:ECO:0000314reference:PMID:20369020provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-29'term:GO:0005634part_of:evidence:    -term:ECO:0000315reference:PMID:20369020provenances:      -contributor:https://orcid.org/0000-0002-1706-4196date:'2020-10-28'term:GO:0140367causal_associations:  -evidence:    -term:ECO:0000315reference:PMID:20369020provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-09-26'    -term:ECO:0000315reference:PMID:19837372provenances:      -contributor:https://orcid.org/0000-0002-3013-9906date:'2018-10-31'predicate:RO:0002629downstream_activity:gomodel:568b0f9600000284/580685bd00000135objects:-id:WB:WBGene00006599label:tpa-1 Cele-id:GO:0004674label:protein serine/threonine kinase activity-id:GO:0002225label:positive regulation of antimicrobial peptide production-id:ECO:0000501label:evidence used in automatic assertion-id:ECO:0000315label:mutant phenotype evidence used in manual assertion-id:ECO:0000318label:biological aspect of ancestor evidence used in manual assertion-id:WB:WBGene00006923label:vhp-1 Cele-id:GO:0017017label:MAP kinase tyrosine/serine/threonine phosphatase activity-id:GO:1900425label:negative regulation of defense response to bacterium-id:ECO:0000314label:direct assay evidence used in manual assertion-id:ECO:0000316label:genetic interaction evidence used in manual assertion-id:WB:WBGene00002187label:kgb-1 Cele-id:GO:0005515label:protein binding-id:GO:1900181label:negative regulation of protein localization to nucleus-id:ECO:0000353label:physical interaction evidence used in manual assertion-id:ECO:0000250label:sequence similarity evidence used in manual assertion-id:ECO:0000307label:no evidence data found used in manual assertion-id:GO:0005737label:cytoplasm-id:GO:0005829label:cytosol-id:GO:0009898label:cytoplasmic side of plasma membrane-id:WB:WBGene00000223label:atf-7 Cele-id:WB:WBGene00004055label:pmk-1 Cele-id:WB:WBGene00004758label:sek-1 Cele-id:GO:0004707label:MAP kinase activity-id:GO:0000981label:DNA-binding transcription factor activity, RNA polymerase II-specific-id:GO:0005634label:nucleus-id:GO:0016045label:detection of bacterium-id:GO:0003674label:molecular_function-id:GO:0035591label:signaling adaptor activity-id:WB:WBGene00006575label:tir-1 Cele-id:GO:0004709label:MAP kinase kinase kinase activity-id:WB:WBGene00003822label:nsy-1 Cele-id:GO:0004708label:MAP kinase kinase activity-id:WB:WBGene00012019label:dkf-2 Cele-id:GO:0140367label:antibacterial innate immune response-id:WB:WBGene00011979label:sysm-1 Cele-id:ECO:0000270label:expression pattern evidence used in manual assertion-id:GO:0110165label:cellular anatomical entity

CX2 Conversion

Additional dependencies are required for CX2 conversion. Install them with thecx2 extras:

pip install gocam-py[cx2]

Important

This will attempt to install thepygraphviz package, which requiresGraphviz (version 2.46 or later) to be installed. If you are on MacOS and you installed Graphviz with Homebrew, you may need to set the following environment variables first so thatpygraphviz can find the Graphviz installation:

export GRAPHVIZ_PREFIX=$(brew --prefix graphviz)export CFLAGS="-I${GRAPHVIZ_PREFIX}/include"export LDFLAGS="-L${GRAPHVIZ_PREFIX}/lib"

Then you can convert a GO-CAM model to CX2 with theconvert subcommand:

gocam convert -O cx2 model.yaml

See the CLI help for more information and options:

gocam convert --help

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