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MRMCaov: R package for multi-reader multi-case analysis of variance

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brian-j-smith/MRMCaov

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Getting Started

MRMCaov is an R package for statistical comparison of diagnostictests - such as those based on medical imaging - for which ratings havebeen obtained from multiple readers and on multiple cases. Features ofthe package include the following.

  • Statistical comparisons of diagnostic tests with respect to readerperformance metrics
  • Comparisons based on the ANOVA model of Obuchowski-Rockette and theunified framework of Hillis
  • Reader performance metrics for area under receiver operatingcharacteristic curves (ROC AUCs), partial AUCs, expected utility ofROC curves, likelihood ratio of positive or negative tests,sensitivity, specificity, and user-defined metrics
  • Parametric and nonparametric estimation and plotting of ROC curves
  • Support for factorial, nested, and partially paired study designs
  • Inference for random or fixed readers and cases
  • Conversion of Obuchowski-Rockette to Roe, Metz & Hillis modelparameters and vice versa
  • DeLong, jackknife, and unbiased covariance estimation
  • Compatibility with Microsoft Windows, MacOS, and Linux

Documentation:User Guide

Installation

Enter the following at the R console to install the package.

install.packages("MRMCaov")

Citing the Software

## Text formatcitation("MRMCaov")
To cite MRMCaov in publications, please use the following two references, including the R package URL.  Smith BJ, Hillis SL, Pesce LL (2023). _MCMCaov: Multi-Reader Multi-Case Analysis of Variance_. R package version  0.3.0, <https://cran.r-project.org/package=MRMCaov>.  Smith BJ, Hillis SL (2020). "Multi-reader multi-case analysis of variance software for diagnostic performance  comparison of imaging modalities." In Samuelson F, Taylor-Phillips S (eds.), _Proceedings of SPIE 11316, Medical  Imaging 2020: Image Perception, Observer Performance, and Technology Assessment_, 113160K. doi:10.1117/12.2549075  <https://doi.org/10.1117/12.2549075>, <https://pubmed.ncbi.nlm.nih.gov/32351258>.To see these entries in BibTeX format, use 'print(<citation>, bibtex=TRUE)', 'toBibtex(.)', or set'options(citation.bibtex.max=999)'.
## Bibtex formattoBibtex(citation("MRMCaov"))
@Manual{MRMCaov-package,  author = {Brian J Smith and Stephen L Hillis and Lorenzo L Pesce},  title = {{MCMCaov}: Multi-Reader Multi-Case Analysis of Variance},  year = {2023},  note = {R package version 0.3.0},  url = {https://cran.r-project.org/package=MRMCaov},}@InProceedings{MRMCaov-SPIE2020,  author = {Brian J. Smith and Stephen L. Hillis},  title = {Multi-reader multi-case analysis of variance software for diagnostic performance comparison of imaging modalities},  booktitle = {Proceedings of SPIE 11316, Medical Imaging 2020: Image Perception, Observer Performance, and Technology Assessment},  editor = {Frank Samuelson and Sian Taylor-Phillips},  month = {16 March},  year = {2020},  pages = {113160K},  doi = {10.1117/12.2549075},  url = {https://pubmed.ncbi.nlm.nih.gov/32351258},}

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MRMCaov: R package for multi-reader multi-case analysis of variance

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