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Calculation of clonality (distances) based on color profiles (Saturation, Hue, and Lightness values)
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asalavaty/AutoClone
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AutoClone
is a shiny app for the automatic assessment of clonalitybased on the data generated through genetic cell labelling and lineagetracing assays. The AutoClone app includes three major modes relevant tothe input data. The clonality assessment is a technique used to evaluatethe similarity of cells/fibers generated through a biological process orthrough development. This technique can also be used for lineage tracingof cells/fibers during development. There are several methods forperforming these analyses most of which rely on genetic cell labellingand coloring of the cells. One of the important aspects oflabelling-based lineage tracing and clonal analysis is thequantification and statistical evaluation of the results(i.e. converting visual colors to interpretable statistics). TheAutoClone
app makes it possible for you to automatically perform thesequantifications and statistical analyses.
TheAutoClone
was developed byAdrian (Abbas)Salavaty
Peter D. Currie
To citeAutoClone
, please cite its Zenodo DOI:
- AutoClone: automatic analysis of genetic labelling data andclonality assessment. Abbas Salavaty and Peter D. Currie. (2021).Zenodo.DOI:10.5281/zenodo.5553555.
Please don’t hesitate to report any bugs/issues and request forenhancement or any other contributions. To submit a bug report orenhancement request, please use theAutoClone
GitHub issuestracker.
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Calculation of clonality (distances) based on color profiles (Saturation, Hue, and Lightness values)