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Calculation of clonality (distances) based on color profiles (Saturation, Hue, and Lightness values)

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asalavaty/AutoClone

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Overview

AutoClone is a shiny app for the automatic assessment of clonalitybased on the data generated through genetic cell labelling and lineagetracing assays. The AutoClone app includes three major modes relevant tothe input data. The clonality assessment is a technique used to evaluatethe similarity of cells/fibers generated through a biological process orthrough development. This technique can also be used for lineage tracingof cells/fibers during development. There are several methods forperforming these analyses most of which rely on genetic cell labellingand coloring of the cells. One of the important aspects oflabelling-based lineage tracing and clonal analysis is thequantification and statistical evaluation of the results(i.e. converting visual colors to interpretable statistics). TheAutoClone app makes it possible for you to automatically perform thesequantifications and statistical analyses.

Author

TheAutoClone was developed byAdrian (Abbas)Salavaty

Advisor

Peter D. Currie

Shiny app

AutoClone Shiny Dashboard

How to citeAutoClone

To citeAutoClone, please cite its Zenodo DOI:

  • AutoClone: automatic analysis of genetic labelling data andclonality assessment. Abbas Salavaty and Peter D. Currie. (2021).Zenodo.DOI:10.5281/zenodo.5553555.

How to contribute

Please don’t hesitate to report any bugs/issues and request forenhancement or any other contributions. To submit a bug report orenhancement request, please use theAutoClone GitHub issuestracker.

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Calculation of clonality (distances) based on color profiles (Saturation, Hue, and Lightness values)

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