Danuser Lab DanuserLab

We are leaders of two NIH research centers with national outreach on cancer cell imaging.Funded by NIH grants RM1GM145399 and U54CA268072

Lyda Hill Department of Bioinformatics, Green Center for Systems Biology, UT Southwestern Medical Center
Dallas, Texas
https://www.danuserlab-utsw.org/
https://www.cellularsignaltransduction.org/
https://www.metastasis-imaging.org/
@DanuserLab

Achievements

u-probeu-probePublic
Processing of raw ratiometric biosensor images (for example based on FRET) into fully corrected "ratio maps" or "activation maps" — images showing the localized activation of the biosensor.
MATLAB 7 1
u-tracku-trackPublic
Multiple-particle tracking designed to (1) track dense particle fields, (2) close gaps in particle trajectories resulting from detection failure, and (3) capture particle merging and splitting even…
MATLAB 47 21
u-track3Du-track3DPublic
Multiple particle tracking in dense 3D particle fields complemented with dynamic regions of interest and trackability inferences for the automated exploration of large volumetric sequences.
MATLAB 26 2
u-shape3Du-shape3DPublic
Detect morphological motifs, such as blebs, filopodia, and lamellipodia, from 3D images of surfaces, particularly images of cell surfaces.
MATLAB 29 6
u-signal3Du-signal3DPublic
The computational platform u-signal3D defines a shape-invariant representation of the spatial scales of molecular organization at the cell surface, enabling comparison and machine-learning of signa…
MATLAB 9 2
u-unwrap3Du-unwrap3DPublic
Transform 3D cell surfaces into different representations including topographic maps, 3D spheres, and 2D images for doing optimized quantification, data analysis and machine learning.
Jupyter Notebook 23