Following are my preferred settings for Google Chrome desktop (Updated for version 127.0.6533.88):

• User Profile: No change
• Sync and Google Services: Disable all

• Google Password Manager: Settings - Disable all
• Payment methods: Disable all
• Addresses and more: Disable

• Delete browsing data: No change
• Third-party cookies: Blocked in incognito mode
• Send a Do Not Track request: Enabled
• Ad privacy
  • Ad topics: Disable
  • Site-suggested ads: Disable
  • Ad measurement: Disable
• Security
  • Safe Browsing: Standard protection
  • Always use secure connections: Enabled
  • Use secure DNS: Disabled
• Site Settings
  • Pop-ups and redirects: Don't allow

No change

• Theme: Classic
• Mode: Dark
• Show home button: Your site url
• Show boomarks bar: Disable
• Side panel position: Show on right
• Tab hover preview card: No change (tab preview, tab memory enabled)
• Use system title bar and borders: Disable
• Font size: No change (Medium)
• Customize fonts: No change
• Page zoom: No change (100%)

Search engine: Your Favorite Search Engine

Google Chrome is your default browser

Open a specific page or set of pages: Your site url

• Continue running background apps: Enabled
• Use graphics acceleration where available

• uBlock Origin Lite
• Bitwarden Password Manager
• Raindrop.io bookmark manager
• Dark Reader (Dark Mode content,https://darkreader.org/)