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    FB2025_01,released February 20, 2025
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      FB2025_01,released February 20, 2025
      CV Term Report
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      General Information
      Term lethalID (Ontology)FBcv:0000351 (FlyBase CV)
      DefinitionA phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
      Comment
      Links to External Ontologies
      Annotations
      Records annotated with this termOR any of itsCHILD TERMS
        Results list data frommultiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
      Records annotated with this exact term (annotations to child terms are NOT included)
      Data Class Field Records
      Alleles (FBal) PHENOTYPIC_CLASS  25164
      Insertions (FBti) LETHALITY   6685
      Constructs (FBtp) PHENOTYPIC_CLASS   3905
      Constructs (FBtp) USES      2
      show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
       Full annotation statements 
      Relevant FlyBase reports
       Alleles Insertions Constructs
       lethal(all annotations which use CV term, excluding "NOT" statements)  25164   6685   3907
           lethal| abnormal dorsal/ventral axis specification| maternal effect      2       --       --
           lethal| abnormal dorsal/ventral axis specification| maternal effect| recessive      2       --       --
           lethal| adult stage     34     25      2
           lethal| adult stage| female       --      1       --
           lethal| adult stage| female| cold sensitive      2       --       --
           lethal| adult stage| heat sensitive     13       --       --
           lethal| adult stage| recessive      9      2       --
           lethal| adult stage| recessive| heat sensitive      1       --       --
           lethal| cell autonomous| recessive| somatic clone      1       --       --
           lethal| chemical conditional     11       --      9
           lethal| chemical conditional| recessive      1       --       --
           lethal| cold sensitive     81       --     39
           lethal| conditional     23       --      7
           lethal| conditional| embryonic stage      3       --      3
           lethal| conditional| pupal stage      1       --       --
           lethal| conditional| recessive     14       --       --
           lethal| dominant     26      4      9
           lethal| dominant| cold sensitive     26       --       --
           lethal| dominant| embryonic stage| maternal effect      1      1       --
           lethal| dominant| heat sensitive     43       --      5
           lethal| dominant| male      6      5       --
           lethal| dominant| male limited      2      1       --
           lethal| dominant| maternal effect     31      1      6
           lethal| dominant| maternal effect| heat sensitive      1       --       --
           lethal| dominant| non-rescuable maternal effect      1       --       --
           lethal| dominant| pupal stage| heat sensitive      1       --       --
           lethal| egg stage| maternal effect      6       --       --
           lethal| embryonic stage    117     26     47
           lethal| embryonic stage| germline clone     15      1       --
           lethal| embryonic stage| germline clone| maternal effect      8      1       --
           lethal| embryonic stage| germline clone| maternal effect| recessive     16      3       --
           lethal| embryonic stage| germline clone| neurogenic phenotype| recessive      1       --       --
           lethal| embryonic stage| germline clone| non-rescuable maternal effect      1       --       --
           lethal| embryonic stage| germline clone| non-rescuable maternal effect| recessive     31       --       --
           lethal| embryonic stage| germline clone| recessive      1      1       --
           lethal| embryonic stage| germline clone| recessive| rescuable maternal effect      8       --       --
           lethal| embryonic stage| germline clone| rescuable maternal effect      7       --       --
           lethal| embryonic stage| heat sensitive     11       --      6
           lethal| embryonic stage| homeotic| recessive      1       --       --
           lethal| embryonic stage| male| recessive      1       --       --
           lethal| embryonic stage| maternal effect     26     17       --
           lethal| embryonic stage| maternal effect| recessive     35      9       --
           lethal| embryonic stage| maternal effect| recessive| heat sensitive      1       --       --
           lethal| embryonic stage| non-rescuable maternal effect      3       --       --
           lethal| embryonic stage| non-rescuable maternal effect| recessive      8      2       --
           lethal| embryonic stage| non-rescuable maternal effect| recessive| heat sensitive      1       --       --
           lethal| embryonic stage| recessive     80     25       --
           lethal| embryonic stage| recessive| heat sensitive      1       --       --
           lethal| embryonic stage| recessive| rescuable maternal effect     14      6       --
           lethal| embryonic stage| rescuable maternal effect     22     12       --
           lethal| embryonic stage| rescuable maternal effect| cold sensitive      1       --       --
           lethal| female     91     17     44
           lethal| female limited    138      4    129
           lethal| female limited| cold sensitive      2       --      1
           lethal| female limited| maternal effect      2      2       --
           lethal| female limited| pupal stage      3       --       --
           lethal| female limited| recessive      3      1       --
           lethal| female limited| temperature conditional      2       --       --
           lethal| female| first instar larval stage| recessive      1       --       --
           lethal| female| heat sensitive     10       --      7
           lethal| female| maternal effect| heat sensitive      4       --       --
           lethal| female| maternal effect| recessive      1       --       --
           lethal| female| pupal stage      3      1      1
           lethal| female| recessive     41      4       --
           lethal| female| recessive| heat sensitive      2       --       --
           lethal| first instar larval stage     44     17     20
           lethal| first instar larval stage| germline clone      1      1       --
           lethal| first instar larval stage| germline clone| maternal effect      1       --       --
           lethal| first instar larval stage| heat sensitive      4       --      4
           lethal| first instar larval stage| male| recessive      1       --       --
           lethal| first instar larval stage| maternal effect| recessive      1       --       --
           lethal| first instar larval stage| recessive     20      3       --
           lethal| gap| heat sensitive      1       --       --
           lethal| germline clone     15       --       --
           lethal| germline clone| larval stage      3       --      2
           lethal| germline clone| larval stage| recessive      5      3       --
           lethal| germline clone| late embryonic stage      3      1       --
           lethal| germline clone| male limited      1      1       --
           lethal| germline clone| male| rescuable maternal effect      1      1       --
           lethal| germline clone| mammalian oogenesis stage      1       --       --
           lethal| germline clone| maternal effect     11      4       --
           lethal| germline clone| maternal effect| neurogenic phenotype| recessive      2       --       --
           lethal| germline clone| maternal effect| recessive     22      1       --
           lethal| germline clone| neurogenic phenotype      1       --       --
           lethal| germline clone| neurogenic phenotype| recessive      1       --       --
           lethal| germline clone| neurogenic phenotype| recessive| rescuable maternal effect      1       --       --
           lethal| germline clone| non-rescuable maternal effect      2      2       --
           lethal| germline clone| pharate adult stage      1      1       --
           lethal| germline clone| pharate adult stage| recessive      2       --       --
           lethal| germline clone| recessive      6       --       --
           lethal| germline clone| recessive| rescuable maternal effect     10      1       --
           lethal| germline clone| rescuable maternal effect      7       --       --
           lethal| heat sensitive    550       --    208
           lethal| homeotic     10       --       --
           lethal| homeotic| recessive     13       --       --
           lethal| larval stage    228     77     71
           lethal| larval stage| heat sensitive     17       --     13
           lethal| larval stage| male      2       --       --
           lethal| larval stage| maternal effect      4       --       --
           lethal| larval stage| maternal effect| recessive      2       --       --
           lethal| larval stage| partially| recessive      1       --       --
           lethal| larval stage| recessive    153     56       --
           lethal| larval stage| recessive| heat sensitive      1       --       --
           lethal| larval stage| somatic clone      2       --      2
           lethal| larval stage| temperature conditional      2       --      3
           lethal| late embryonic stage      5      5       --
           lethal| late third instar larval stage      3       --      2
           lethal| late third instar larval stage| recessive      1       --       --
           lethal| male    166     15     71
           lethal| male limited    138      5    126
           lethal| male limited| chemical conditional      2       --      2
           lethal| male limited| cold sensitive     81       --     81
           lethal| male limited| heat sensitive      2       --      3
           lethal| male limited| maternal effect      1       --      1
           lethal| male limited| recessive      1       --       --
           lethal| male limited| third instar larval stage      2       --      1
           lethal| male limited| third instar larval stage| temperature conditional      2       --      2
           lethal| male| cold sensitive      1       --       --
           lethal| male| heat sensitive     11       --      6
           lethal| male| pharate adult stage      2       --      1
           lethal| male| pupal stage      2       --       --
           lethal| male| recessive     53      2       --
           lethal| male| recessive| cold sensitive      1       --       --
           lethal| male| recessive| heat sensitive      1       --       --
           lethal| maternal effect    261     27     17
           lethal| maternal effect| cold sensitive      3       --       --
           lethal| maternal effect| heat sensitive     17       --       --
           lethal| maternal effect| non-rescuable maternal effect      1       --       --
           lethal| maternal effect| pupal stage      2       --       --
           lethal| maternal effect| recessive    298     21       --
           lethal| maternal effect| recessive| cold sensitive      8       --       --
           lethal| maternal effect| recessive| heat sensitive     15       --       --
           lethal| maternal effect| semidominant      1       --       --
           lethal| maternal effect| somatic clone      1      1       --
           lethal| neurogenic phenotype      9       --       --
           lethal| neurogenic phenotype| heat sensitive      2       --      2
           lethal| neurogenic phenotype| recessive     10      1       --
           lethal| neurogenic phenotype| recessive| heat sensitive      1       --       --
           lethal| neurogenic phenotype| rescuable maternal effect      2       --       --
           lethal| non-rescuable maternal effect      6      1       --
           lethal| non-rescuable maternal effect| heat sensitive      1       --       --
           lethal| non-rescuable maternal effect| recessive     18      1       --
           lethal| non-rescuable maternal effect| recessive| heat sensitive      1       --       --
           lethal| nutrition conditional     15       --     11
           lethal| P-stage     38      2     23
           lethal| P-stage| recessive     11       --       --
           lethal| parental effect      3      1      2
           lethal| partially| heat sensitive      2       --       --
           lethal| partially| pupal stage| recessive      1       --       --
           lethal| paternal effect      9       --      6
           lethal| paternal effect| recessive      2       --       --
           lethal| pharate adult stage    157     83     33
           lethal| pharate adult stage P10      2       --       --
           lethal| pharate adult stage P14      2       --      3
           lethal| pharate adult stage P15      9       --      8
           lethal| pharate adult stage P15(ii)      4       --      3
           lethal| pharate adult stage P8| heat sensitive      1       --      1
           lethal| pharate adult stage| heat sensitive      4       --      3
           lethal| pharate adult stage| recessive     17      7       --
           lethal| pharate adult stage| temperature conditional      1       --      1
           lethal| prepupal stage     69     60      1
           lethal| prepupal stage P1      1       --      1
           lethal| prepupal stage P2      2       --       --
           lethal| prepupal stage P4(ii)      1       --      1
           lethal| prepupal stage| heat sensitive      2       --      2
           lethal| prepupal stage| recessive      4      1       --
           lethal| pupal stage    486    109    311
           lethal| pupal stage P5      7       --      3
           lethal| pupal stage P5(i)      1       --      1
           lethal| pupal stage P7      2       --      1
           lethal| pupal stage| cold sensitive      3       --      2
           lethal| pupal stage| heat sensitive     16       --     15
           lethal| pupal stage| recessive     95     34       --
           lethal| pupal stage| recessive| heat sensitive      2       --       --
           lethal| pupal stage| recessive| somatic clone      2       --       --
           lethal| pupal stage| somatic clone      4       --      2
           lethal| pupal stage| temperature conditional      3       --      4
           lethal| recessive  14390   5228     17
           lethal| recessive| cold sensitive     42       --       --
           lethal| recessive| heat sensitive    161       --      2
           lethal| recessive| rescuable maternal effect     15      4       --
           lethal| recessive| rescuable maternal effect| heat sensitive      1       --       --
           lethal| recessive| second instar larval stage      9       --       --
           lethal| recessive| temperature conditional      3       --       --
           lethal| recessive| third instar larval stage      8      4       --
           lethal| recessive| third instar larval stage| heat sensitive      1       --       --
           lethal| rescuable maternal effect     92      3       --
           lethal| rescuable maternal effect| heat sensitive      1       --       --
           lethal| RU486 conditional     19       --     12
           lethal| second instar larval stage     21      6      8
           lethal| semidominant     11       --       --
           lethal| semidominant| cold sensitive      1       --       --
           lethal| semidominant| heat sensitive      1       --       --
           lethal| somatic clone     18      2      5
           lethal| somatic clone| third instar larval stage      1       --       --
           lethal| temperature conditional     20       --     13
           lethal| tetracycline conditional      3       --      2
           lethal| third instar larval stage     33      6     16
      Spanning Tree (Parents/Children)
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      increased mortality   |__increased mortality during development       |__lethal46582 rec.           |__lethal - all die before end of P-stage17451 rec.           |   |__lethal - all die before end of pupal stage(+)14950 rec.           |   |__lethal - all die during P-stage(+)2084 rec.           |__lethal - all die during immature adult stage6 rec.
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      Is aincreased mortality during development
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