Movatterモバイル変換

General Information

Symbol

Dmel\ND-75^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0326165

Feature type

allele

Associated gene

Dmel\ND-75

Associated Insertion(s)

Carried in Construct

P{UAS-ND-75.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-ND-75.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of an RNAi line that targetsND-75.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

ND-75

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ /EMBL /GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

autophagosome |cell non-autonomous |somatic clone |third instar larval stage, withScer\GAL4^ap.PU

(Katheder et al., 2017)

wing disc dorsal compartment |cell non-autonomous |somatic clone |third instar larval stage, withScer\GAL4^ap.PU

(Katheder et al., 2017)

Detailed Description

Statement

Reference

The expression ofND-75^{dsRNA.Scer\UAS.cUa} under the control ofScer\GAL4^ap.PU results in increased levels of autophagosomes (assessed by aAtg8a fluorescence reporter) in the dorsal compartment of third instar larval wing discs, as compared to controls.

(Katheder et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ND-75^RNAi.UAS.cUa

ND-75^{dsRNA.Scer\UAS.cUa}

ND-75^{dsRNA.UAS.cUa}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close