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General Information

Symbol

Dmel\Ddrgk1^GD3098

Species

D. melanogaster

Name

FlyBase ID

FBal0204851

Feature type

allele

Associated gene

Dmel\Ddrgk1

Associated Insertion(s)

Carried in Construct

P{GD3098}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD3098}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD3098

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ /EMBL /GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage, withScer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

lethal - all die during P-stage, withScer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

some die during pupal stage, withScer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, withDcr-2^UAS.cDa,Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, withScer\GAL4^tin.CΔ4

(Neely et al., 2010)

visible, withScer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

mesonotum, withScer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

trichogen cell, withScer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Detailed Description

Statement

Reference

Adults expressingCG5862^GD3098 under the control ofScer\GAL4^elav.PLu (in the presence ofDcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

Expression under the control ofScer\GAL4^Mef2.PR results in late pupal lethality.

(Schnorrer et al., 2010)

Expression under the control ofScer\GAL4^pnr-MD237 may result in lethality, depending on the insertion line used.

Expression under the control ofScer\GAL4^pnr-MD237 results in bristle morphology defects on the notum in 20-30% of theScer\GAL4^pnr-MD237 expression domain.

Expression under the control ofScer\GAL4^pnr-MD237 results in the absence of 80-90% of theScer\GAL4^pnr-MD237-expressing area of the notum.

(Mummery-Widmer et al., 2009)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

3098

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v45155

w¹¹¹⁸; P{GD3098}v45155/TM3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

3098

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG5862^GD3098

Ddrgk1^GD3098

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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