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| Clinical data | |
|---|---|
| Trade names | Cophylac |
| ATC code | |
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| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | 100% |
| Metabolism | liver |
| Eliminationhalf-life | 14 days |
| Excretion | Urine |
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| CAS Number | |
| PubChemCID | |
| ChemSpider |
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| UNII | |
| KEGG |
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| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.006.730 |
| Chemical and physical data | |
| Formula | C20H25NO |
| Molar mass | 295.426 g·mol−1 |
| 3D model (JSmol) | |
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Normethadone (INN,BAN; brand namesTicarda,Cophylac,Dacartil,Eucopon,Mepidon,Noramidone,Normedon, and others), also known asdesmethylmethadone orphenyldimazone, is asyntheticopioidanalgesic andantitussive agent.[citation needed]Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grams. It has an effective span of action for about 14 days, and is 12 to 20 times stronger than morphine.[2] The salts in use are the hydrobromide (free base conversion ratio 0.785), hydrochloride (0.890), methyliodide (0.675), oxalate (0.766), picrate (0.563), and the 2,6-ditertbutylnapthalindisulphonate (0.480).[3]
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